[Objective] To analyze the influencing factors of repeat blood donor lapsing using a zero-inflated poisson regression model (ZIP). [Methods] The blood donation behavior of 12 498 whole blood donors from 2020 was tracked until December 31, 2023. The factors influencing the frequency of blood donations in a given year was analyzed using ZIP, and donors with 0 blood donation in that year were considered to have lapsed. The changes in relevant influencing factors associated with each blood donation were measured and modeled for analysis. [Results] The zero-inflated part of ZIP showed that the risk of lapsing of male blood donors was 2.24 times that of female blood donors (OR 95% CI:1.864-2.696, P<0.001); the risk of lapsing of the 35-44 age group and over 45 age group was respectively 40% (OR 95% CI:0.455-0.790, P<0.001) and 61%(OR 95% CI:0.268-0.578, P<0.001) lower than that of the under 25 age group; the risk of lapsing for those who have donated blood twice and ≥3 times was respectively 50% (OR 95% CI:0.405-0.609, P<0.001) and 81% (OR 95% CI:0.154-0.225, P<0.001) lower than that of first-time donors; the risk of lapsing of those with junior high or high school education was 1.2 times that of those with a college degree or higher (OR 95% CI:1.033-1.384, P<0.05); the risk of lapsing for the divorced group was 2.02 times that of the married group (OR 95% CI:1.445-2.820, P<0.001); the risk of lapsing for those with an income (Yuan) of 10 000 to 50 000, 50 000 to 100 000 and more than 100 000 was respectively 0.67 (OR 95% CI:0.552-0.818, P<0.001), 0.72 (OR 95% CI:0.591-0.884, P=0.002) and 0.67 (OR 95% CI:0.535-0.834, P<0.001) times that of those with an income (Yuan) of less than 10 000. The results of the Poisson part are consistent with the results of the zero-inflated part in terms of age and education level. [Conclusion] Blood donor lapsing is overall related to factors such as gender, age, donation frequency, education, marital status and family income. It's essential to care for those blood donors prone to lapse to retain more regular blood donors.

[Objective] To explore the characteristics of lifestyle behaviors and mental health status among blood donors in Guangzhou, and to investigate the correlation between donation frequency and these factors. [Methods] A cross-sectional study was conducted among 13 042 whole blood donors from 17 street blood donation sites of Guangzhou Blood Center from May to August 2020. Descriptive analysis was used to describe the characteristics of lifestyle behaviors and mental health status among blood donors in Guangzhou. Ordinal multinomial logistic regression model was used to analyze the correlation between donation frequency and these factors. [Results] It was found that some of 13 042 blood donors had unhealthy habits, such as 6.8% (698/10 214，2 828 missing values) had severe tobacco dependence, 30.6% (3 997/13 042) had low exercise levels, 38.8%（5 056/13 042）had poor sleep quality, and 2.2% (271/12 159，883 missing values) had alcohol dependence. In addition, 2.8% (364/13 042) and 1.3% (172/13 042) of the donors may have moderate to severe depression and anxiety symptoms, respectively. The results of the ordinal multinomial logistic regression model showed that exercise level was significantly negatively correlated with the degree of depression and anxiety among blood donors. With the decrease in exercise level, the possibility of depression and anxiety among donors increased significantly. BMI, household income, education level, marital status, donation frequency, alcohol consumption and smoking had no significant correlation with the mental health status of donors. [Conclusion] Improving the exercise habits of blood donors may help enhance their mental health level. It is recommended that blood station staff strengthen the content of exercise when providing health education to blood donors to maintain a healthy lifestyle. It also suggests that there may be a certain degree of under-diagnosis of mental health problems in the process of health consultation before blood donation, and conducting more comprehensive and effective mental health assessments for blood donors is recommended.

【Objective】 To compare the effects of 3 rehydration methods before blood donation on the prevention of on-site and delayed blood donation-related vasovagal response (VVR) . 【Methods】 From January to June 2021, 6 250 whole blood donors in 6 fixed blood donation sites signed informed consent and were divided into 198 clusters according to donor sites and dates, then they were randomly assigned to receive either oral rehydration salts (ORS), sugar water, or water group, and each drank 500 mL of ORS, sugar water or water within 20 minutes before blood donation. The researchers recorded the actual intervention accepted on site, and recorded the immediate VVR and related information. At rest after blood donation, donors submitted an electronic questionnaire containing socio-demographic information. At 48 hours after blood donation, the researchers called back every donor to record delayed VVR and related information. Logistic regression based on intention to treat (ITT) was used to analyze the difference of the incidence of VVR among the three groups, and the average treatment effect on treated (ATT) was calculated. PASS 2021was used to estimate the sample size and R (4.2.0) for statistical analysis. 【Results】 The cumulative incidence of blood donation-related VVR was 2.67% (2.29%-3.11%) among street whole blood donors under the 3 rehydration methods, in which, the incidence of immediate and delayed VVR was 1.02% (0.79%-1.31%) and 1.65% (1.36%-2.01%) respectively. ITT analysis found that ORS were more effective than water in reducing the incidence of delayed VVR【OR=0.59,95% CI[0.37,0.94]】.There was no significant difference in the incidence of immediate VVR between any two groups (P > 0.05), and there was no significant difference in the incidence of delayed VVR in the sugar water group compared with the water group (P > 0.05). There was a difference of -0.013 (【95% CI[-0.022, -0.004]】or -0.008【95% CI[-0.017, -0.000]】in the incidence of delayed VVR in the ORS group compared with water group or sugar water group, the difference was significant (P<0.05). The cumulative VVR of the three groups showed similar results to the delayed VVR. 【Conclusion】 Drinking ORS before blood donation is the most effective rehydration method to prevent delayed VVR. The next step is to establish the predictive model of delayed VVR to screen the susceptible population and provide them with ORS before blood donation, while other population can choose any liquid they like, thus achieving personalized blood donation-related VVR prevention and control.

【Objective】 To investigate the prevalence of depression in blood donors and analyze the related factors, so as to develop a rapid depression screening model for blood donors. 【Methods】 A total of 13 015 street whole blood donors in Guangzhou Blood Center during May to August, 2020 filled in an anonymous e-questionnaire, including social demography information and the Patient Health Questionnaire-9 before donation. The cut-off value for detecting depression was 10. Logistic regression by SPSS 26.0 was used to analyze depression related factors. 2-level decision tree with 30/10 as the minimum number of cases in parent/child node, 10-fold cross validation was used to cut items of PHQ-9 to form the depression screening model. 【Results】 364 out of 13 015 (2.80%) street whole blood donors reported a score ≥ 10. Donors with 18-29 years old (P <0.05), unmarried (P<0.05), less than 50 000 RMB household income per year (P< 0.05) were more prone to depression. 81.96% donors in "<10 scores" group, while 3.85%donors in "≥ 10 scores" group were in two terminal nodes formed by Item-6, 2 and 4 of PHQ-9. After verification by the 10 fold crossover method, the estimated misclassification risk of the model was 1.7%. 【Conclusion】 The screening prevalence of depression based on PHQ-9 in Guangzhou blood donors was 2.8%(95% CI: 2.52%-3.09%) . Donation frequency was not related to depression. A rapid and efficient depression screening model for blood donors based on item-6, 2 and 4 of PHQ-9 was developed.

Objective Analyze the characteristics of delayed apheresis platelet donors due to health consultation or ex-amination,and the influencing factors of recall in Guangzhou,and to provide evidence for recruitment strategy.Methods 5 960 delayed apheresis platelet donors from January fisrt,2022 to June 30th,2022 were collected in Guangzhou Blood Center and fol-lowed up to August31th,2023.Logistic regression analysis was used to analyze the influence of sex,age,times of blood donation and length of blood donation on recall.Results Among the 5 960 delayed platelet donors,164(2.75%)were permanently un-suitable for blood donation.The most common reason was allergy.Among the 5 796(97.25%)delayed blood donors,the most common reason was abnormal blood routine.Analysis of factors associated with delayed donor recall found that male donors were more likely than female donors[OR =1.16,95%CI(1.01,1.34)],blood donors aged 26-35[OR =1.65,95%CI(1.41,1.92)],36-45[OR=1.90,95%CI(1.55,2.31)]or 46-60[OR =2.63,95%CI(1.96,3.53)]compared with those aged 18-25,blood donors who were blocked forless than 14 days[OR =4.22,95%CI(2.73,6.52)]orfor 15-89 days[OR =5.24,95%CI(3.42,8.03)]compared with those who were blocked for more than or equal to 90 days,the recall rate of repeat donors was higher than that of first-time donors[OR=6.78,95%CI(5.62,8.19)].Conclusion In order to improve the recall rate of apheresis platelet donors,we should pay more attention to the education of young donors and first-time donors,also consider a voluntary recall by text message or phone after a donor has been prevented from donating blood.

【Objective】 To analyze the related factors affecting first-time platelet donors to become regular donors in Guangzhou in 2018, so as to provide reference for the retention of platelet donors. 【Methods】 The data of 4 361 first-time platelet donors in Guangzhou in 2018, including age, gender, initial donation unit, time for the primary and secondary donation were collected. The relevant factors affecting first-time blood donors to become regular donors were analyzed by Logistic regression analysis. 【Results】 Among the influencing factors, first-time donors returned in the first month were more likely to become regular donors (5.569 times that of those did not return)(OR 95% CI: 4.748~6.533, P<0.05). First-time donors who aged 45~60, and initially donated 2 units were more likely to become regular donors than those aged 18~24(1.857 times) (OR 95% CI: 1.413~2.441, P<0.05), and those initially donated only one unit (1.695 time) (OR 95% CI: 1.486~1.933, P<0.05). 【Conclusion】 The returning in the first month, age and initial donation units predict long-term commitment for first-time donors. Encouraging first-time platelet donors to return within 1 month is more likely to convert them into regular blood donors.

【Objective】 To apply the spatial distribution analysis based on ArcGIS software, which has been applied widely in other fields, so as to analyze the intended locations for whole blood donation. 【Methods】 After a random stratified sampling was conducted among blood donors in the 17 donation sites during August 1st, 2021- July 30th, 2022, their intended blood donation locations were collected by an e-questionnaire. Addresses of donors′ intended donation locations were derived for GCJ-02 coordinates form and transformed by pandas module of Python to WGS84 coordinates, which further loaded to ArcGIS Arcmap module using Grouping Analysis for 17 median centers. The addresses of 17 blood donation sites in Guangzhou Blood Center were transformed to WGS84 coordinates and loaded to ArcGIS Arcmap module using the same methods for 3 ring buffer analysis. The criterion for judging whether the two were " matched" was whether the intended blood donation sites were covered by or adjacent to the 3 ring buffer zone of the existing blood donation sites. 【Results】 Of the 17 potential sites obtained from the spatial distribution analysis of 40 523 valid addresses of donors, 8 sites were covered or adjacent to the buffer of the existing donation sites, while the other 9 sites were far away from the existing donation sites. 【Conclusion】 By analyzing the spatial distribution of donors′ intended donation addresses, we can find out the service needs of donors for donating blood conveniently, which can provide basis for further blood donation service optimization.

【Objective】 To further determine the relationship between blood donor role cognition and blood donation behavior, then prepare of blood donor role identity scale(BDRIS). 【Methods】 The preparation of the scale was divided into five stages. It includes literature retrieval, expert interview, construction of the basic framework of the scale, scale test and statistical index test. The study focused on items selection, dimensions identification, measurement reliability, content and structural validity. 【Results】 The blood donor role identity scale consisted of 35 items. Exploratory factor analysis divided the items into six common factors, including role identity, role expectation, current situation of blood collection and supply, role conflict, external reward and blood donation experience. The α of scale was 0.840. 【Conclusion】 The reliability and validity of the scale meet the basic measurement requirements, and the framework of the blood donor role scale is basically formed. It can be used as one of the means to explore the ways and mechanisms of the role identity of blood donors in blood donation behavior.

【Objective】 To analyze the researches on blood donation service during 2001 to 2020, explore the development of blood donation service in China and discover the hot spots and weaknesses in current research, aimed to provide reference for future research. 【Methods】 The research team, institutions and hotspots of related literature from China National Knowledge Infrastructure (CNKI) were analyzed using CiteSpace. 【Results】 After analyzing the selected 969 relevant literature, it is concluded that there is few communication between the core author teams. The inter-agency research network is not mature enough, and the cooperation and communication between institutions need to be further strengthened. The high-frequency keywords were volunteer donors, satisfaction, blood donation response and humanized service. Quality control in the blood donation service process, maintenance and recruitment of regular blood donors, and the establishment and improvement of voluntary blood donation teams were research hot spots. 【Conclusion】 China has made fruitful achievements in the research of blood donation service after 20 years of development. The key point of future research is to strengthen the cooperation between different research teams, integrate the first-line practice of blood collection and supply, as well as explore the individualized and localized theory of blood donation service.

【Objective】 To obtain HTLV prevalence data among blood donors in mainland China through meta-analyze, and provide reference for relevant policies. 【Methods】 The literature concerning HTLV prevalence among blood donors in mainland China before April 15, 2021 in CNKI, Wanfang and Pubmed was searched. According to the inclusion criteria and exclusion criteria, relative literature within recent 10 years was screened and then analyzed by meta-analysis using R3.3. 【Results】 A total of 69 articles were included, covering 22 provincial administrative regions, with a total sample size of 7 435 501 cases. 535 cases were HTLV positive, of which 491 centred on three coastal provinces as Fujian, Guangdong and Zhejiang, and 44 scattered in 11 other provincial administrative regions. The pooled prevalence of HTLV in blood donors in Fujian, Guangdong and Zhejiang provinces were 3.25/10 000(95%CI 1.91/10 000~4.58/10 000), 0.13/10 000(95%CI 0.09/10 000~0.17/10 000) and 0.33/10 000(95%CI 0.06/10 000~0.61/10 000), respectively. Subgroup analysis showed that the pooled prevalence of HTLV in Fujian blood donors decreased since December 2015. 【Conclusion】 Blood donors in mainland China present low HTLV prevalence, mainly distributed in three coastal provinces as Fujian, Guangdong and Zhejiang. The sample size tested increased greatly since HTLV screening for blood donors was popularized nationwide in blood stations in December 2015, the infection rate of HTLV in Fujian, however, did not increase as expected.