Objective:To investigate the treatment of congenital skin defects in neonates.Methods:11 newborns with congenital skin defects were admitted to our department, including 10 males and 1 female. After admission, various life indexes and skin defects were evaluated. Newborns were nursed in a constant temperature incubator, with individualized fluid replenishment, anti-shock, anti-infection and nutritional support to strengthen nursing and maintain the function of each organ. All skin defect wounds were cleaned and disinfected with 0.01% Benzalkonium chloride solution, and treated with wet dressing. The growth of new epithelium was observed.Results:One of the 11 cases was complicated with septicaemia, and 3 cases were examined histopathologically. After dressing change, all the 11 newborns were cured, and the wound healed from 7 to 29 days, with an average of 21.3 days. 2 years later, 10 patients were followed up. The wound healed well, without obvious scar formation, functional activities were not affected, and some areas had mild pigmentation.Conclusions:For newborns with congenital skin defects, maintaining the function of organs as soon as possible, changing local dressing and strengthening nursing care can promote wound healing and skin structure and function recovery.

With the development of social economy and the progress of medical technology, more and more women begin to accept vaginal contraction due to the harmony of sexual life. Now, surgical procedures for vaginal contraction includes resection of posterior vaginal mucosa, contraction without injury of vaginal mucosa, and contraction with embedded vaginal thread. This review aims to summurize the anatomic structure of vagina and the mechanism of vaginal relaxation, as well as the basic operative methods and development of vaginal contraction. The related literature on vaginal contraction at home and abroad was summarized. Different surgical methods have their own advantages and disadvantages.

Objective To analyze the clinical efficacy of negative pressure wound therapy(NPWT)combined with pig decellularized dermal matrix(ADM)on the repair of limb deep burn wound.Methods From March 21,2015 to January 18,2016,102 patients with limb deep burn wounds in the Affiliated Hospital of Binzhou Medical College were selected,and randomly divided into conventional group and observation group,with 51 cases in cach group.The conventional group was treated with ADM dressing alone,and NPWT+ADM was used in the experimental group.The therapeutic effect was compared between the two groups.Results The drainage fluid volume after treatment for 21d in the observation group was(18.65 ±1.23)mL,which was significantly less than that in the conventional group[(48.36 ±3.12)mL,t=63.265,P=0.000].The wound healing rates of the observation group after treatment for 7d(t=153.829,P=0.000),14d(t=53.786,P=0.000),21d(t=70.763,P=0.000)were significantly higher than those of the conventional group.The wound healing time of the observation group[(18.86 ±1.52)d]was significantly shorter than the conventional group [(28.32 ±1.76)d,t=29.050,P=0.000].Conclusion For patients with limb deep burn wounds,NPWT combined with ADM treatment has remarkable effect,can obviously improve the clinical symptoms,promote disease recovery,it is worthy of popularizing.