1.Friendship in the nursing workplace: A concept analysis
Philippine Journal of Nursing 2023;93(2):74-77
Friendships are essential to human function and survival and are one of the many influences affecting health, well-being, and
happiness in both personal and professional life. This concept analysis aims to clarify the meaning of friendship among
professional nurses by presenting the attributes, antecedents, and consequences of friendship and discussing surrogate terms
and model cases.
Friends
2.IL-17-Producing Cells in Tumor Immunity: Friends or Foes?
Da Sol KUEN ; Byung Seok KIM ; Yeonseok CHUNG
Immune Network 2020;20(1):6-
IL-17 is produced by RAR-related orphan receptor gamma t (RORγt)-expressing cells including Th17 cells, subsets of γδT cells and innate lymphoid cells (ILCs). The biological significance of IL-17-producing cells is well-studied in contexts of inflammation, autoimmunity and host defense against infection. While most of available studies in tumor immunity mainly focused on the role of T-bet-expressing cells, including cytotoxic CD8⁺ T cells and NK cells, and their exhaustion status, the role of IL-17-producing cells remains poorly understood. While IL-17-producing T-cells were shown to be anti-tumorigenic in adoptive T-cell therapy settings, mice deficient in type 17 genes suggest a protumorigenic potential of IL-17-producing cells. This review discusses the features of IL-17-producing cells, of both lymphocytic and myeloid origins, as well as their suggested pro- and/or anti-tumorigenic functions in an organ-dependent context. Potential therapeutic approaches targeting these cells in the tumor microenvironment will also be discussed.
Animals
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Autoimmunity
;
Child
;
Child, Orphaned
;
Friends
;
Humans
;
Inflammation
;
Interleukin-17
;
Killer Cells, Natural
;
Lymphocytes
;
Mice
;
T-Lymphocytes
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Th17 Cells
;
Tumor Microenvironment
3.A systematic review of barriers and motivators to physical activity in elderly adults in Iran and worldwide
Soudabeh YARMOHAMMADI ; Hossein MOZAFAR SAADATI ; Mohtasham GHAFFARI ; Ali RAMEZANKHANI
Epidemiology and Health 2019;41(1):2019049-
OBJECTIVES: This study was conducted to identify and characterize the barriers and motivations to physical activity (PA) for elderly adults in Iran and other countries.METHODS: We searched 6 databases (PubMed, Embase, Scopus, Web of Science, Magiran, and the Scientific Information Database) from 2000 to the November 2017, using “aged 60 and over,” “physical activity” or “exercise,” and “motivator” and “barrier” as keywords. Two reviewers independently performed the search, screening, and quality assessment of the studies.RESULTS: In total, 34 papers were finally included in the study. The most important barriers, based on the frequency of factors, included physical problems, having no companions, and physical barriers to walking. The motivators included improving one's physical condition, being social, and suitability of the physical environment.CONCLUSIONS: Important motivators and barriers to PA were more closely related to intrapersonal factors than to the interpersonal and environmental domains. The barriers and motivators to PA in the elderly were not markedly different between Iran and other countries. Therefore, a general strategy could be designed to improve PA in the elderly.
Adult
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Aged
;
Aging
;
Architectural Accessibility
;
Friends
;
Humans
;
Iran
;
Mass Screening
;
Motivation
;
Motor Activity
;
Walking
4.Individual and regional factors associated with suicidal ideation among Korean elderly: a multilevel analysis of the Korea Community Health Survey
Sang Hee JEONG ; Byung Chul CHUN
Epidemiology and Health 2019;41(1):2019022-
OBJECTIVES: This study aimed to identify the individual and regional characteristics that influence suicidal ideation among the Korean elderly population.METHODS: Using data collected from the 2013 Korea Community Health Survey, a multilevel analysis was performed to establish an understanding of individual behavioral patterns and regional influences on suicidal ideation.RESULTS: Among the 77,407 individuals sampled, 11,236 (14.5%) elderly people over 60 years of age experienced suicidal ideation. Among individual factors, age, frequency of communication with friends, religious activity, social activity, leisure activity, trust in neighbors, subjective stress level, depressive symptoms, and subjective health status were significantly associated with suicidal ideation. The results showed that the lower the regional deprivation level, the higher the suicidal ideation odds ratio. In terms of regional size, the most significant effects were found in rural areas.CONCLUSIONS: This study suggested that suicidal ideation in the elderly is associated with community factors, such as the regional deprivation index, as well as personal factors.
Age Factors
;
Aged
;
Depression
;
Diagnostic Self Evaluation
;
Friends
;
Health Surveys
;
Humans
;
Korea
;
Leisure Activities
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Multilevel Analysis
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Odds Ratio
;
Socioeconomic Factors
;
Suicidal Ideation
5.AI, big data, and robots for the evolution of biotechnology
Genomics & Informatics 2019;17(4):44-
Artificial intelligence (AI), big data, and ubiquitous robotic companions —the three most notable technologies of the 4th Industrial Revolution—are receiving renewed attention each day. Technologies that can be experienced in daily life, such as autonomous navigation, real-time translators, and voice recognition services, are already being commercialized in the field of information technology. In the biosciences field in Korea, such technologies have become known to the local public with the introduction of the AI doctor Watson in large number of hospitals. Additionally, AlphaFold, a technology resembling the AI AlphaGo for the game Go, has surpassed the limit on protein folding predictions—the most challenging problems in the field of protein biology. This report discusses the significance of AI technology and big data on the bioscience field. The introduction of automated robots in this field is not just only for the purpose of convenience but a prerequisite for the real sense of AI and the consequent accumulation of basic scientific knowledge.
Artificial Intelligence
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Biology
;
Biotechnology
;
Friends
;
Humans
;
Korea
;
Protein Folding
;
Voice
6.Effects of Sleep Pattern, Stress, Menstrual Attitude, and Behavior That Reduces Exposure to Endocrine Disrupting Chemicals on Premenstrual Syndrome in Adolescents
Hye Jin KIM ; So Young CHOI ; Haeyoung MIN
Korean Journal of Women Health Nursing 2019;25(4):423-433
PURPOSE: The study aimed to examine the effects of sleep pattern, stress, and attitude towards menstruation, and behavior that causes a reduction in exposure to endocrine disrupting chemicals (EDCs) in the course of premenstrual syndrome (PMS) in female adolescents.METHOD: In total, 200 girls attending middle school in K city were recruited via convenience sampling between December 11 and 31, 2018, and 192 subjects were selected for the analysis. Data were analyzed using descriptive statistics, an independent t-test, ANOVA, Pearson's correlation coefficient, and multiple regression.RESULTS: Overall, 9 (4.7%), 152 (79.2%), and 31 (16.1%) students had morning-, intermediate-, and evening-type sleep pattern, respectively. The mean scores for school-related stress were highest. Scores for stress regarding relationships with friends were the lowest. The mean score for attitudes toward menstruation was 72.33 out of 147. The mean score for behavior that led to a reduction in EDCs exposure was 56.57 out of 85. The mean scores for PMS severity were 25.30 and 38.39 out of 60. Analysis of factors affecting PMS revealed that severity of menstrual pain (β=.28), use of analgesics during menstruation (β=.17), family history of PMS (β=−.16), stress (β=.19), and behavior that reduces EDCs exposure (β=−.17) exerted significant effects on PMS. The explanatory power of these variables was 37%.CONCLUSION: The findings propose the necessity of a health intervention program including educational information, which can reduce PMS in adolescents, induce the behaviors which can decrease exposure to EDCs, and activities for managing the stress levels.
Adolescent
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Analgesics
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Dysmenorrhea
;
Endocrine Disruptors
;
Female
;
Friends
;
Humans
;
Menstruation
;
Methods
;
Premenstrual Syndrome
7.Nuclear Theranostics in Asia: In vivo Companion Diagnostics
Nuclear Medicine and Molecular Imaging 2019;53(1):1-6
No abstract available.
Asia
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Friends
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Humans
;
Theranostic Nanomedicine
8.Interpersonal violence epidemiology and mortality by violence victim-perpetrator relationships
Shinyung CHOU ; Sung Wook SONG ; Woo Jeong KIM ; Youngjoon KANG ; Hyun Soo PARK ; Kyeong Won KANG ; Chang Bae PARK ; Jeong Ho KANG ; Ji Hwan BU ; Sung Kgun LEE ; Seo Young KO
Journal of the Korean Society of Emergency Medicine 2019;30(2):120-131
OBJECTIVE: The aim of this study was to investigate the interpersonal violence (IPV) epidemiology and mortality according to the violence victim-perpetrator relationships. METHODS: A retrospective cross-sectional study was done using the comprehensive data of the emergency department (ED)-based Jeju Injury Surveillance System from all EDs in Jeju Island. The demographic characteristics of the victims, the types of perpetrators (spouse, family members, acquaintance, and stranger), injury characteristics and clinical outcomes from the injury were collected. The IPV epidemiology was reported by descriptive statistics. Multivariate Poisson regression was used to analyze the association between the mortality and violence victim-perpetrator relationships. RESULTS: Among the 23,508 violent injury patients enrolled from January 1, 2008, and December 31 of 2016, 19,879 (84.6%) were analyzed; 16 (0.08%) died at the ED. The types of perpetrators were the spouse (10.1%), family members (3.9%), acquaintances (43.4%), and strangers (42.7%). The mortality of the violence victims was increased significantly by the spouse (incidence rate ratio [IRR], 6.336; P=0.043) or family members (IRR, 11.089; P=0.016) compared to strangers. On the other hand, there was no difference between the acquaintances and strangers. CONCLUSION: The epidemiology and mortality of IPV were associated with the violence victim-perpetrator relationships. Therefore, it is necessary to develop and apply prevention programs considering these differences, particularly for intimidate/ family violence because of its high fatality.
Cross-Sectional Studies
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Domestic Violence
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Emergency Service, Hospital
;
Epidemiology
;
Friends
;
Hand
;
Humans
;
Interpersonal Relations
;
Mortality
;
Retrospective Studies
;
Spouses
;
Violence
9.Factors Influencing Intention of Sexual Abstinence Among Female College Students Based on the Theory of Planned Behavior
Journal of the Korean Society of Maternal and Child Health 2019;23(2):115-125
PURPOSE: This study aimed to identify the factors that impact the intention of sexual abstinence among female college students. The approach was based on Ajzen's theory of planned behavior and the parent-adolescent communication of contextual factors. METHODS: A total of 189 female university students in the first to fourth grades at two universities in Honam region participated in the study. The collected data were analyzed using hierarchical stepwise multiple regression using SPSS 21.0. RESULTS: The major factor that influences the intention of sexual abstinence among female college students was attitudes toward sexual behavior (β=0.53, p<0.001). Other factors, in descending order of their impact, were subjective norms toward friends (β=0.25, p<0.001), experience of sexual intercourse (β=−0.19, p<0.001), and subjective norms toward parents (β=0.09, p=0.040). Taken together, the aforementioned factors explained 81.1 % of the total variance. CONCLUSION: Female college students' intention to abstain from sexual behaviors requires education promoting moderate and conservative positions. The participants' subjective norms concerning sexual behaviors as perceived by friends and parents were also important. The results of this study provide meaningful implications for education of parents, sexual education of female college students, and sexual counseling programs.
Coitus
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Counseling
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Education
;
Female
;
Friends
;
Humans
;
Intention
;
Parents
;
Sexual Abstinence
;
Sexual Behavior
10.Antibacterial effects of sodium tripolyphosphate against Porphyromonas species associated with periodontitis of companion animals
Jae Hyung LEE ; Ji Hoi MOON ; Jae In RYU ; Sang Wook KANG ; Kyu Hwan KWACK ; Jin Yong LEE
Journal of Veterinary Science 2019;20(4):e33-
Porphyromonas species are closely associated with companion animal periodontitis which is one of the most common diseases in dogs and cats and leads to serious systemic diseases if left untreated. In this study, we evaluated the antimicrobial effects and mode of action of sodium tripolyphosphate (polyP3, Na5P3O10), a food additive with proven safety, using three pathogenic Porphyromonas species. The minimum inhibitory concentrations (MICs) of polyP3 against Porphyromonas gulae, Porphyromonas cansulci, and Porphyromonas cangingivalis were between 500 and 750 mg/L. PolyP3 significantly decreased viable planktonic cells as well as bacterial biofilm formation, even at sub-MIC concentrations. PolyP3 caused bacterial membrane disruption and this effect was most prominent in P. cangingivalis, which was demonstrated by measuring the amount of nucleotide leakage from the cells. To further investigate the mode of action of polyP3, high-throughput whole-transcriptome sequencing was performed using P. gulae. Approximately 30% of the total genes of P. gulae were differentially expressed by polyP3 (> 4-fold, adjusted p value < 0.01). PolyP3 influenced the expression of the P. gulae genes related to the biosynthesis of thiamine, ubiquinone, and peptidoglycan. Collectively, polyP3 has excellent antibacterial effects against pathogenic Porphyromonas species and can be a promising agent to control oral pathogenic bacteria in companion animals.
Animals
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Bacteria
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Biofilms
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Cats
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Dogs
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Food Additives
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Friends
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Humans
;
Membranes
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Microbial Sensitivity Tests
;
Peptidoglycan
;
Periodontitis
;
Pets
;
Plankton
;
Porphyromonas
;
Sodium
;
Thiamine
;
Ubiquinone


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