1.Prevention and treatment of postoperative complications of esophageal cancer.
Chinese Journal of Gastrointestinal Surgery 2023;26(4):330-333
		                        		
		                        			
		                        			Surgery is the primary treatment for esophageal cancer, but the postoperative complication rate remains high. Therefore, it is important to prevent and manage postoperative complications to improve prognosis. Common perioperative complications of esophageal cancer include anastomotic leakage, gastrointestinal tracheal fistula, chylothorax, and recurrent laryngeal nerve injury. Respiratory and circulatory system complications, such as pulmonary infection, are also quite common. These surgery-related complications are independent risk factors for cardiopulmonary complications. Complications, such as long-term anastomotic stenosis, gastroesophageal reflux, and malnutrition are also common after esophageal cancer surgery. By effectively reducing postoperative complications, the morbidity and mortality of patients can be reduced, and their quality of life can be improved.
		                        		
		                        		
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Quality of Life
		                        			;
		                        		
		                        			Postoperative Complications/prevention & control*
		                        			;
		                        		
		                        			Anastomotic Leak/etiology*
		                        			;
		                        		
		                        			Esophageal Neoplasms/surgery*
		                        			;
		                        		
		                        			Prognosis
		                        			;
		                        		
		                        			Esophagectomy/adverse effects*
		                        			;
		                        		
		                        			Digestive System Fistula/surgery*
		                        			;
		                        		
		                        			Retrospective Studies
		                        			
		                        		
		                        	
2.Dong's extraordinary point needling technique combined with medication for postoperative complications of anal fistula: a randomized controlled trial.
Yan FU ; Yue XU ; Hai-Xia WU ; Shan-Shan WANG
Chinese Acupuncture & Moxibustion 2023;43(8):916-920
		                        		
		                        			OBJECTIVE:
		                        			To observe the effect of Dong's extraordinary point needling technique on postoperative complications of anal fistula.
		                        		
		                        			METHODS:
		                        			A total of 241 patients undergoing anal fistula surgery were randomly divided into an observation group (121 cases, 3 cases dropped off) and a control group (120 cases, 2 cases dropped off). The patients in the control group were treated with intramuscular injection of compound diclofenac sodium injection and oral administration of tamsulosin hydrochloride sustained release capsules. In addition to the treatment in the control group, the patients in the observation group were treated with Daoma needling technique at the "Sanqi points" (Qimen point, Qijiao point, and Qizheng point) combined with Dongqi needling technique at "Sanhuang points" (sub-Tianhuang point, Dihuang point, Renhuang point), with each session lasting 30 min. The treatment in the two groups both started on the first day after surgery, and was given once daily for 14 consecutive days. Visual analog scale (VAS) score was compared between the two groups on postoperative day 1, 7, and 14; bladder residual urine volume, spontaneous voiding volume, and urinary catheterization frequency were assessed after treatment on postoperative day 1; and anorectal dynamic indexes (anal canal resting pressure, rectal resting pressure, maximum squeeze pressure of the anal canal, and minimum rectal sensory threshold) were evaluated before surgery and on postoperative day 4. Clinical efficacy was assessed in both groups one month after surgery.
		                        		
		                        			RESULTS:
		                        			On postoperative day 7 and 14, the VAS scores of both groups were lower than those on postoperative day 1 (P<0.05), and the VAS scores in the observation group were lower than those in the control group (P<0.05). The bladder residual urine volume and urinary catheterization frequency in the observation group were lower than those in the control group (P<0.05), while the spontaneous voiding volume was higher than that in the control group (P<0.05). On postoperative day 4, the anal canal resting pressure, maximum squeeze pressure of the anal canal, and the minimum rectal sensory threshold were lower than preoperative values (P<0.05), while the rectal resting pressure was higher than preoperative value (P<0.05) in both groups. The anal canal resting pressure, maximum squeeze pressure of the anal canal, and minimum rectal sensory threshold were lower than those in the control group, and the rectal resting pressure was higher than that in the control group (P<0.05). The effective rate was 93.2% (110/118) in the observation group, which was higher than 84.7% (100/118) in the control group (P<0.05).
		                        		
		                        			CONCLUSION
		                        			Dong's extraordinary point needling technique could reduce postoperative pain, alleviate urinary retention, and improve defecation in patients undergoing anal fistula surgery.
		                        		
		                        		
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Rectum
		                        			;
		                        		
		                        			Rectal Fistula/surgery*
		                        			;
		                        		
		                        			Anal Canal/surgery*
		                        			;
		                        		
		                        			Treatment Outcome
		                        			;
		                        		
		                        			Anus Diseases
		                        			;
		                        		
		                        			Postoperative Complications/etiology*
		                        			;
		                        		
		                        			Acupuncture Points
		                        			
		                        		
		                        	
3.Effect of muscle relaxants on the prognosis of neonates with congenital esophageal atresia-tracheoesophageal fistula after surgery.
Wen-Wen HE ; Jing-Wen WENG ; Shi-Xiao DONG ; Fei JIN ; Hai-Lan WU ; Ming-Yan HEI
Chinese Journal of Contemporary Pediatrics 2021;23(7):735-738
		                        		
		                        			OBJECTIVE:
		                        			To summarize the experience in the application of muscle relaxants in the perioperative period in neonates with congenital esophageal atresia-tracheoesophageal fistula (EA-TEF).
		                        		
		                        			METHODS:
		                        			A retrospective analysis was performed on the medical data of 58 previously untreated neonates with EA-TEF who were treated in the Neonatal Center of Beijing Children's Hospital, Capital Medical University from 2017 to 2019. The incidence rate of anastomotic leak was compared between the neonates receiving muscle relaxants for different durations after surgery (≤ 5 days and > 5 days). The correlation between the duration of postoperative use of muscle relaxants and the duration of mechanical ventilation was evaluated.
		                        		
		                        			RESULTS:
		                        			Among the 58 neonates with EA-TEF, 44 underwent surgery, among whom 35 with type III EA-TEF underwent thoracoscopic surgery. Among these 35 neonates, 30 (86%) received muscle relaxants after surgery, with a median duration of 4.75 days, and 6 (18%) experienced anastomotic leak. There was no significant difference in the incidence rate of anastomosis leak between the ≤ 5 days and > 5 days groups (
		                        		
		                        			CONCLUSIONS
		                        			Prolonged use of muscle relaxants after surgery cannot significantly reduce the incidence of anastomotic leak, but can prolong the duration of invasive mechanical ventilation in neonates with EA-TEF. Therefore, prolonged use of muscle relaxants is not recommended after surgery.
		                        		
		                        		
		                        		
		                        			Child
		                        			;
		                        		
		                        			Esophageal Atresia/surgery*
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Infant, Newborn
		                        			;
		                        		
		                        			Muscles
		                        			;
		                        		
		                        			Postoperative Complications/etiology*
		                        			;
		                        		
		                        			Prognosis
		                        			;
		                        		
		                        			Retrospective Studies
		                        			;
		                        		
		                        			Tracheoesophageal Fistula/surgery*
		                        			;
		                        		
		                        			Treatment Outcome
		                        			
		                        		
		                        	
4.Omentum Transplantation in Thorax to Cover Bronchial Stump as Treatment of Bronchopleural Fistula After Pulmonary Resection: Report of 6 Cases' Experience.
Xiaozun YANG ; Xiaojun YANG ; Tianpeng XIE ; Bin HU ; Qiang LI
Chinese Journal of Lung Cancer 2018;21(3):235-238
		                        		
		                        			BACKGROUND:
		                        			Bronchial pleural fistula (BPF) is a common complication after thoracic surgery for lung resection. Clinical treatment is complex and the effect is poor. The treatment of BPF after lung resection has plagued thoracic surgeons. We reviewed retrospectively the clinical and follow-up data of 6 patients in our hospital who underwent the omentum transplantation in thorax to cover bronchial stump as treatment of BPF after pulmonary resection to analyze why BPF occurs and describe this treatment method. We intend to discuss and evaluate the feasibility, safety and small sample success rate ofthis treatment method.
		                        		
		                        			METHODS:
		                        			During August 2016 to February 2018, six patients in our hospital underwent remedial open thoracotomy and omentum transplantation in pleura space to cover bronchial stump as treatment of bronchopleural fistula after pulmonary resection. Four patients had undergone a prior pneumonectomy and two patients had undergone a prior lobectomy (the residual lungs were resected with the main bronchus cut by endoscopic stapler during the reoperation). The bronchial stumps were sutured by 4-0 string with needle and covered by omentums, which were transplanted in pleura space from the cardiophrenic angle. Postoperatively, the pleura space was irrigated and drained. Summarize the clinical effect and technique learning points.
		                        		
		                        			RESULTS:
		                        			The patients were all males, aged 61 to 73 years (median age: 66). BPF occurred from postoperative day 10 to 45 (median postoperative day 25). The reoperation was finished in 80 mins-150 mins (median 110 mins). Total blood loss was 200 mL-1,000 mL (median 450 mL). These patients were discharged on postoperative day 12-17 (median 14 days), and there was no more complications associated with bronchopleural fistula. All six patients' bronchial stumps were well closed (100%) and have recovered well during the follow-up period, which lasted 1 month-18 months.
		                        		
		                        			CONCLUSIONS
		                        			Remedial operation should be performed as soon as possible when BPF after pulmonary resection diagnosed. Excellent prognoses can be achieved by omentum which is easy to get transplanted in thorax to cover bronchial stump as treatment in patients with BPF after pulmonary resection those who can tolerate reoperation.
		                        		
		                        		
		                        		
		                        			Aged
		                        			;
		                        		
		                        			Bronchi
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Bronchial Fistula
		                        			;
		                        		
		                        			etiology
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Lung
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Lung Neoplasms
		                        			;
		                        		
		                        			complications
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Omentum
		                        			;
		                        		
		                        			transplantation
		                        			;
		                        		
		                        			Pleura
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Pleural Diseases
		                        			;
		                        		
		                        			etiology
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Pneumonectomy
		                        			;
		                        		
		                        			adverse effects
		                        			;
		                        		
		                        			Postoperative Complications
		                        			;
		                        		
		                        			etiology
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Retrospective Studies
		                        			;
		                        		
		                        			Thoracotomy
		                        			
		                        		
		                        	
5.Diagnosis and treatment of duodenal injury and fistula.
Kunmei GONG ; Shikui GUO ; Kunhua WANG
Chinese Journal of Gastrointestinal Surgery 2017;20(3):266-269
		                        		
		                        			
		                        			Duodenal injury is a serious abdominal organ injury. Duodenal fistula is one of the most serious complications in gastrointestinal surgery, which is concerned for its critical status, difficulty in treatment and high mortality. Thoracic and abdominal compound closed injury and a small part of open injury are common causes of duodenal injury. Iatrogenic or traumatic injury, malnutrition, cancer, tuberculosis, Crohn's disease etc. are common causes of duodenal fistula, however, there has been still lacking of ideal diagnosis and treatment by now. The primary treatment strategy of duodenal fistula is to determine the cause of disease and its key point is prevention, including perioperative parenteral and enteral nutrition support, improvement of hypoproteinemia actively, avoidance of stump ischemia by excessive separate duodenum intraoperatively, performance of appropriate duodenum stump suture to ensure the stump blood supply, and avoidance of postoperative input loop obstruction, postoperative stump bleeding or hematoma etc. Once duodenal fistula occurs, a simple and reasonable operation can be selected and performed after fluid prohibition, parenteral and enteral nutrition, acid suppression, enzyme inhibition, anti-infective treatment and maintaining water salt electrolyte and acid-base balance. Double tube method, duodenal decompression and peritoneal drainage can reduce duodenal fistula-related complications, and then reduce the mortality, which can save the lives of patients.
		                        		
		                        		
		                        		
		                        			Abdominal Injuries
		                        			;
		                        		
		                        			complications
		                        			;
		                        		
		                        			Anti-Infective Agents
		                        			;
		                        		
		                        			therapeutic use
		                        			;
		                        		
		                        			Decompression, Surgical
		                        			;
		                        		
		                        			Digestive System Surgical Procedures
		                        			;
		                        		
		                        			adverse effects
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Drainage
		                        			;
		                        		
		                        			Duodenal Diseases
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			etiology
		                        			;
		                        		
		                        			prevention & control
		                        			;
		                        		
		                        			therapy
		                        			;
		                        		
		                        			Duodenum
		                        			;
		                        		
		                        			blood supply
		                        			;
		                        		
		                        			injuries
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Enteral Nutrition
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Hypoproteinemia
		                        			;
		                        		
		                        			therapy
		                        			;
		                        		
		                        			Intestinal Fistula
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			etiology
		                        			;
		                        		
		                        			prevention & control
		                        			;
		                        		
		                        			therapy
		                        			;
		                        		
		                        			Ischemia
		                        			;
		                        		
		                        			prevention & control
		                        			;
		                        		
		                        			Nutritional Support
		                        			;
		                        		
		                        			Parenteral Nutrition
		                        			;
		                        		
		                        			Postoperative Complications
		                        			;
		                        		
		                        			prevention & control
		                        			;
		                        		
		                        			therapy
		                        			;
		                        		
		                        			Suture Techniques
		                        			;
		                        		
		                        			Thoracic Injuries
		                        			;
		                        		
		                        			complications
		                        			
		                        		
		                        	
6.Comparison of complications following open, laparoscopic and robotic gastrectomy.
Xin LAN ; Hongqing XI ; Kecheng ZHANG ; Jianxin CUI ; Mingsen LI ; Lin CHEN
Chinese Journal of Gastrointestinal Surgery 2017;20(2):184-189
OBJECTIVETo compare clinically relevant postoperative complications after open, laparoscopic, and robotic gastrectomy for gastric cancer.
METHODSClinical data of patients with gastric cancer who underwent gastrectomy between January 1, 2014 and October 1, 2016 at Chinese People's Liberation Army General Hospital were analyzed retrospectively. All the patients were diagnosed by upper endoscopy and confirmed by biopsy without distant metastasis. They were confirmed with R0 resection by postoperative pathology. Patients with incomplete data were excluded. The complications among open group, laparoscopic group and robotic group were compared. The continuous variables were analyzed by one-way ANOVA, and categorical variables were analyzed by χtest or Fisher exact test.
RESULTSA total of 1 791 patients (1 320 males and 471 females) were included in the study, aged from 17 to 98 (59.0±11.6) years, comprising 922 open, 673 laparoscopic and 196 robotic gastrectomies. There were no significant differences among three groups in baseline data (gender, age, BMI, comorbidity, radiochemotherapy) and some of operative or postoperative data (blood transfusion, number of lymph node dissection, combined organ resection, resection site, N stage, postoperative hospital stay). The blood loss in laparoscopic and robotic groups was significantly lower than that in open group[(185.7±139.6) ml and (194.0±187.6) ml vs. (348.2±408.5) ml, F=59.924, P=0.000]. The postoperative complication occurred in 197 of 1 791(11.0%) patients. The Clavien-Dindo II(, III(a, III(b, IIII(a, and IIIII( complications were 5.5%, 4.0%, 1.2%, 0.1%, and 0.2% respectively. The anastomotic leakage (2.4%), intestinal obstruction(1.3%) and pulmonary infection(1.2%) were the three most common complications, followed by wound infection(0.8%), cardiovascular disease(0.7%), anastomotic bleeding (0.7%), delayed gastric emptying (0.6%), duodenal stump fistula(0.5%), intraperitoneal hemorrhage (0.5%), pancreatic fistula (0.3%), intra-abdominal infection(0.2%), chylous leakage (0.1%) and other complications(1.7%). There were no significant differences among three groups as the complication rates of open, laparoscopic and robotic gastrectomy were 10.6%(98/922), 10.8%(73/673) and 13.3%(26/196) respectively (χ=1.173, P=0.566). But anastomotic leakage occurred more common after laparoscopic and robotic gastrectomy compared to open gastrectomy [3.1%(21/673) and 5.1%(10/196) vs. 1.3%(12/922), χ=12.345, P=0.002]. The rate of cardiocerebral vascular diseases was higher in open group[1.3%(12/922) vs. 0.1%(1/673) and 0, χ=8.786, P=0.012]. And the rate of anastomotic bleeding was higher in robotic group [2.0%(4/196) vs. open 0.4%(4/922) and laparoscopic 0.6%(4/673), χ=6.365, P=0.041]. In view of Clavien-Dindo classification, III(a complications occurred more common in laparoscopic group [5.5%(37/673) vs. open 3.3%(30/922) and robotic 2.6%(5/196), χ=6.308, P=0.043] and III(b complications occurred more common in robotic group [3.1%(6/196) vs. open 1.1%(10/922) and laparoscopic 0.7%(5/673), χ=7.167, P=0.028].
CONCLUSIONSMorbidities of postoperative complications are comparable among open, laparoscopic and robotic gastrectomy for gastric cancer. However, in consideration of the high difficulty of anastomosis, the minimally invasive surgery should be performed by more experienced surgeons.
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Anastomotic Leak ; epidemiology ; etiology ; Blood Loss, Surgical ; statistics & numerical data ; Cerebrovascular Disorders ; epidemiology ; etiology ; Chylous Ascites ; epidemiology ; etiology ; Comorbidity ; Comparative Effectiveness Research ; Duodenal Diseases ; epidemiology ; etiology ; Female ; Gastrectomy ; adverse effects ; methods ; Gastrointestinal Hemorrhage ; epidemiology ; etiology ; Gastroparesis ; epidemiology ; etiology ; Gastroscopy ; Hemoperitoneum ; epidemiology ; etiology ; Humans ; Intestinal Fistula ; epidemiology ; etiology ; Intraabdominal Infections ; epidemiology ; etiology ; Laparoscopy ; adverse effects ; Length of Stay ; Lymph Node Excision ; Male ; Middle Aged ; Postoperative Complications ; epidemiology ; etiology ; Postoperative Hemorrhage ; epidemiology ; etiology ; Postoperative Period ; Respiratory Tract Infections ; epidemiology ; etiology ; Retrospective Studies ; Risk Assessment ; Robotic Surgical Procedures ; adverse effects ; Stomach Neoplasms ; surgery ; Surgical Wound Infection ; epidemiology ; etiology
7.Value of endoscopy application in the management of complications after radical gastrectomy for gastric cancer.
Chinese Journal of Gastrointestinal Surgery 2017;20(2):160-165
		                        		
		                        			
		                        			Endoscopy plays an important role in the diagnosis and treatment of postoperative complications of gastric cancer. Endoscopic intervention can avoid the second operation and has attracted wide attention. Early gastric anastomotic bleeding after gastrectomy is the most common. With the development of technology, emergency endoscopy and endoscopic hemostasis provide a new treatment approach. According to the specific circumstances, endoscopists can choose metal clamp to stop bleeding, electrocoagulation hemostasis, local injection of epinephrine or sclerotherapy agents, and spraying specific hemostatic agents. Anastomotic fistula is a serious postoperative complication. In addition to endoscopically placing the small intestine nutrition tube for early enteral nutrition support treatment, endoscopic treatment, including stent, metal clip, OTSC, and Over-stitch suture system, can be chosen to close fistula. For anastomotic obstruction or stricture, endoscopic balloon or probe expansion and stent placement can be chosen. For esophageal anastomotic intractable obstruction after gastroesophageal surgery, radial incision of obstruction by the hook knife or IT knife, a new method named ERI, is a good choice. Bile leakage caused by bile duct injury can be treated by placing the stent or nasal bile duct. In addition, endoscopic methods are widely used as follows: abdominal abscess can be treated by the direct intervention under endoscopy; adhesive ileus can be treated by placing the catheter under the guidance of endoscopy to attract pressure; alkaline reflux gastritis can be rapidly diagnosed by endoscopy; gastric outlet obstruction mainly caused by cancer recurrence can be relieved by metal stent placement and the combination of endoscopy and X-ray can increase success rate; pyloric dysfunction and spasm caused by the vagus nerve injury during proximal gastrectomy can be treated by endoscopic pyloromyotomy, a new method named G-POEM, and the short-term outcomes are significant. Endoscopic submucosal dissection (ESD) allows complete resection of residual gastric precancerous lesions, however it should be performed by the experienced endoscopists.
		                        		
		                        		
		                        		
		                        			Anastomosis, Surgical
		                        			;
		                        		
		                        			adverse effects
		                        			;
		                        		
		                        			Bile Ducts
		                        			;
		                        		
		                        			injuries
		                        			;
		                        		
		                        			Constriction, Pathologic
		                        			;
		                        		
		                        			etiology
		                        			;
		                        		
		                        			therapy
		                        			;
		                        		
		                        			Digestive System Fistula
		                        			;
		                        		
		                        			etiology
		                        			;
		                        		
		                        			therapy
		                        			;
		                        		
		                        			Duodenogastric Reflux
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			etiology
		                        			;
		                        		
		                        			Endoscopy, Gastrointestinal
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Enteral Nutrition
		                        			;
		                        		
		                        			instrumentation
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Gastrectomy
		                        			;
		                        		
		                        			adverse effects
		                        			;
		                        		
		                        			Gastric Outlet Obstruction
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Gastritis
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			Gastrointestinal Hemorrhage
		                        			;
		                        		
		                        			etiology
		                        			;
		                        		
		                        			therapy
		                        			;
		                        		
		                        			Hemostasis, Endoscopic
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Hemostatics
		                        			;
		                        		
		                        			administration & dosage
		                        			;
		                        		
		                        			therapeutic use
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Neoplasm Recurrence, Local
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Postoperative Complications
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			therapy
		                        			;
		                        		
		                        			Precancerous Conditions
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Pylorus
		                        			;
		                        		
		                        			innervation
		                        			;
		                        		
		                        			physiopathology
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Stents
		                        			;
		                        		
		                        			Stomach Neoplasms
		                        			;
		                        		
		                        			complications
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Treatment Outcome
		                        			;
		                        		
		                        			Vagus Nerve Injuries
		                        			;
		                        		
		                        			etiology
		                        			;
		                        		
		                        			surgery
		                        			
		                        		
		                        	
8.Efficacy of over-the-scope clip for gastrointestinal fistula.
Gefei WANG ; Zhiming WANG ; Xiuwen WU ; Yanqing DIAO ; Yunzhao ZHAO ; Jianan REN ; Jieshou LI
Chinese Journal of Gastrointestinal Surgery 2017;20(1):79-83
OBJECTIVETo explore the efficacy of over-the-scope clip (OTSC) in the treatment of gastrointestinal fistula.
METHODSClinical data of 12 gastrointestinal fistula patients, including 3 internal fistula and 9 external fistula treated with OTSC in our institute from March 2015 to May 2016 were retrospectively analyzed. OTSC was performed when pus was drained thoroughly and intra-abdominal infection around gastrointestinal fistula was controlled, and each patient received one clip to close fistula.
RESULTSThere were 6 female and 6 male patients with mean age of (50.1±12.6) years. The successful rate of endoscopic closure was 100% without complications including bleeding and intestinal obstruction during and after OTSC treatment. According to comprehensive evaluation, including drainage without digestive juices, no recurrence of intra-abdominal infection, no overflow of contrast medium during digestive tract radiography, and CT examination without intra-abdominal abscess, clinical gastrointestinal fistula closure was 91.7%(11/12). There was no recurrence of gastrointestinal fistula during 3 months of follow-up in 11 patients. In the remaining 1 case, the gastric fistula after laparoscopic sleeve gastrectomy recurred one week after OTSC treatment because of intra-abdominal infection surrounding fistula, and was cured by surgery finally.
CONCLUSIONThe endoscopic closure treatment of OTSC for gastrointestinal fistula is successful and effective, and control of intra-abdominal infection around fistula with adequate drainage is the key point.
Adult ; Digestive System Fistula ; complications ; drug therapy ; surgery ; Drainage ; Endoscopy, Gastrointestinal ; instrumentation ; methods ; Female ; Humans ; Intraabdominal Infections ; etiology ; therapy ; Male ; Middle Aged ; Recurrence ; Retrospective Studies ; Suppuration ; therapy ; Surgical Fixation Devices
9.Clinical research of delta-shaped anastomosis technology in laparoscopic distal gastrectomy and digestive tract reconstruction.
Bo GAO ; Qingxing HUANG ; Jianhong DONG
Chinese Journal of Gastrointestinal Surgery 2017;20(1):73-78
OBJECTIVETo evaluate the feasibility and safety of the delta-shaped anastomosis in laparoscopic distal gastrectomy and digestive tract reconstruction.
METHODSClinical data of 34 gastric cancer patients undergoing laparoscopic distal gastrectomy with the delta-shaped anastomosis for digestive tract reconstruction (delta-shaped group) and 83 gastric cancer patients undergoing laparoscopic distal gastrectomy with Billroth I( for digestive tract reconstruction (Billroth group) by same surgeon team from July 2013 to July 2015 at the Department of Digestive Surgery, Affiliated Tumor Hospital of Shanxi Medical University were retrospectively analyzed. Data of two groups were compared.
RESULTAge, gender, tumor stage were not significantly different between the two groups(all P>0.05). Operation time of the first 15 cases in delta-shaped group was longer than that in Billroth group [(254.7±35.4) min vs. (177.8±33.0) min, t=11.190, P=0.000], while after above 15 cases, the operation time of delta-shaped group was significantly shorter than that of Billroth group [(142.1±14.6) min vs. (177.8±33.0) min, t=-4.109, P=0.001]. Delta-shaped group had less blood loss during operation [(87.1±36.7) ml vs. (194.0±55.1) ml, t=-10.268, P=0.000], and shorter length of incision [(4.1±0.4) cm vs. (6.1±1.0) cm, t=-10.331, P=0.000] than Billroth group. Compared with Billroth group, delta-shaped group presented faster postoperative bowel function return [(2.8±0.6) d vs. (3.3±0.5) d, t=-3.755, P=0.000], earlier liquid food intake [(7.4±1.5) d vs. (8.1±1.7) d, t=-4.135, P=0.000], earlier ambulation [(4.0±1.6) d vs. (6.8±1.4) d, t=-7.197, P=0.000] and shorter postoperative hospital stay [(12.6±1.9) d vs.(13.6±2.0) d, t=-20.149, P=0.000]. Morbidity of postoperative complication was 5.9%(2/34) in delta-shaped group, including anastomotic fistula in 1 case and incision infection in 1 case, and 6.0%(5/83) in Billroth group, including anastomotic fistula, incision infection, anastomotic stricture and dumping syndrome, without significant difference(P>0.05). Difference value of total protein and albumin between pre-operation and post-operation, and average decreased value of total protein, albumin, body weight between pre-operation and postoperative 6-month were not significantly different between two groups(all P>0.05). As for patients with BMI > 25 kg/m, compared to Billroth group, delta-shaped group presented less blood loss during operation [(94.1±36.7) ml vs. (203.0±55.1) ml, t=-10.268, P=0.000], lower injective dosage of postoperative analgesics [(1.9±1.1) ampule vs.(3.3±2.0) ampule, t=-2.188, P=0.032], faster intestinal recovery [(2.9±0.7) d vs. (3.2±0.9) d, t=-3.755, P=0.009], shorter hospital stay [(10.5±1.2) d vs. (11.7±1.5) d, t=-2.026, P=0.004], and lower morbidity of postoperative complication [7.1%(1/14) vs. 13.6%(3/22), χ=4.066, P=0.031].
CONCLUSIONIn laparoscopic distal gastrectomy and digestive tract reconstruction, the delta-shaped anastomosis is safe and feasible, especially suitable for obese patients.
Anastomosis, Surgical ; adverse effects ; methods ; Blood Loss, Surgical ; statistics & numerical data ; Comparative Effectiveness Research ; Constriction, Pathologic ; epidemiology ; etiology ; Defecation ; Digestive System Fistula ; epidemiology ; etiology ; Drinking ; Dumping Syndrome ; epidemiology ; etiology ; Female ; Gastrectomy ; adverse effects ; methods ; Gastroenterostomy ; adverse effects ; methods ; Humans ; Laparoscopy ; adverse effects ; methods ; Length of Stay ; Male ; Operative Time ; Postoperative Complications ; epidemiology ; Postoperative Period ; Recovery of Function ; Retrospective Studies ; Stomach Neoplasms ; surgery ; Surgical Wound ; Surgical Wound Infection ; epidemiology ; Treatment Outcome
10.Efficacy comparison of robotic and laparoscopic radical surgery in the treatment of middle-low rectal cancer.
Hairong ZHANG ; Weitang YUAN ; Quanbo ZHOU ; Xiaoming GU ; Fuqi WANG
Chinese Journal of Gastrointestinal Surgery 2017;20(5):540-544
OBJECTIVETo compare the clinical efficacy of robotic and laparoscopic radical surgery in the treatment of middle-low rectal cancers.
METHODSFrom January 2015 to March 2016, intra-operative and postoperative follow-up data of 30 patients with middle-low rectal cancers who underwent robotic radical resection(robot group) and 32 patients with middle-low rectal cancers who underwent laparoscopic radical resection (laparoscopy group)n in our department were retrospectively collected. The distance from cancer to anal margin was less than 10 cm in both two groups and advanced rectal cancers were confirmed by preoperative colonoscopy biopsy. Associated data were compared between two groups.
RESULTSThere were 13 males and 17 females in robot group with age of 27 to 85 (mean 59.7) years, disease course of 3 to 12 (mean 6.2) months and clinical stage T2-3N0-1. There were 16 males and 16 females in laparoscopic group with age of 32 to 79 (mean 60.3) years, disease course of 2 to 10(mean 5.9) months and clinical stage T2-3N0-1. The baseline data of two groups were not significantly different (all P>0.05). All the patients in two groups completed operations successfully without conversion to open operation. Compared with laparoscopic group, the blood loss was less [(100.3±43.7) ml vs. (150.3±68.2) ml, t=3.413, P=0.001], the first flatus time [(49.3±12.4) h vs. (58.6±12.5) h, t=2.838, P=0.006] and urinary catheter removal time [(3.0±0.7) d vs. (4.8±0.9) d, t=5.491, P=0.000] were shorter, while the operation time [(217.3±57.8) min vs. (187.9±23.1) min, t=2.772, P=0.009] was longer in robot group. No cancer tissue was observed in resection margin of two groups. Number of harvested lymph node per case (15.2±7.4 vs. 13.9±4.9, t=-0.764, P=0.448), distance from anal margin to tumor distal edge [(7±3) cm vs. (6.5±3) cm, t=-1.952, P=0.056] and postoperative hospital stay [(13.6±1.3) d vs. (13.8±1.8) d, t=0.925, P=0.359] were not significantly different between two groups. No serious complications occurred in two groups during intra-operative and postoperative period. During following up of 3 to 12 (average 8.7) months, 1 case of anastomotic fistula occurred in each group and was cured by conservative treatment without significant difference [3.3%(1/30) vs. 3.1%(1/32), P=1.000]. No sexual dysfunction was found in either groups. Two cases in laparoscopic group presented relapse and metastasis, but no recurrence and metastasis was observed in robot group. There was no death in two groups.
CONCLUSIONRobotic radical surgery in the treatment of middle-low rectal cancers is safe and effective with the advantages of less trauma, less bleeding, rapid recovery of intestinal function and urinary function.
Adult ; Aged ; Blood Loss, Surgical ; Comparative Effectiveness Research ; Defecation ; Digestive System Surgical Procedures ; adverse effects ; methods ; Female ; Fistula ; etiology ; surgery ; Humans ; Laparoscopy ; adverse effects ; Length of Stay ; Lymph Node Excision ; Male ; Middle Aged ; Neoplasm Metastasis ; Neoplasm Recurrence, Local ; Operative Time ; Postoperative Period ; Recovery of Function ; Rectal Neoplasms ; surgery ; Retrospective Studies ; Robotic Surgical Procedures ; adverse effects ; Treatment Outcome ; Urination
            
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