1.Periorbital Lipogranuloma after Facial Autologous Fat Injection and Its Treatment Outcomes.
Korean Journal of Ophthalmology 2016;30(1):10-16
		                        		
		                        			
		                        			PURPOSE: To investigate periorbital lipogranuloma cases that developed after autologous fat injection and to determine various treatment outcomes from these cases. METHODS: This retrospective study involved 27 patients who presented with periocular mass (final diagnosis of lipogranuloma) and had history of facial autologous fat injection. The collected data included information on patient sex, age, clinical presentation, number and site of fat injections, interval between injections, duration from injection to symptom onset, fat harvesting site, use of cryopreservation, and treatment outcome. RESULTS: The most common presenting symptom was palpable mass (92.6%), followed by blepharoptosis and eyelid edema. The mean time from injection to symptom onset was 13.6 +/- 29.2 months (range, 2 to 153 months). Patients were managed by intralesional triamcinolone injection (six patients) and surgical excision (three patients); 18 patients were followed without treatment. Among the six patients who underwent intralesional triamcinolone injection, five showed complete resolution, and one showed partial resolution. Among the 18 patients who were followed without management, three showed spontaneous resolution over a 5-month follow-up period. CONCLUSIONS: Lipogranuloma can develop in the eyelid after autologous fat injection into the face. Both surgical excision and intralesional triamcinolone injection yield relatively good outcomes. Simple observation can be a good option because spontaneous resolution can occur in a subset of patients.
		                        		
		                        		
		                        		
		                        			Adipose Tissue/*transplantation
		                        			;
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Autografts
		                        			;
		                        		
		                        			Cosmetic Techniques/*adverse effects
		                        			;
		                        		
		                        			Eyelid Diseases/diagnostic imaging/*etiology/therapy
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Granuloma, Foreign-Body/diagnostic imaging/*etiology/therapy
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Injections
		                        			;
		                        		
		                        			Magnetic Resonance Imaging
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Orbital Diseases/diagnostic imaging/*etiology/therapy
		                        			;
		                        		
		                        			Retrospective Studies
		                        			;
		                        		
		                        			Rhytidoplasty/*adverse effects
		                        			;
		                        		
		                        			Young Adult
		                        			
		                        		
		                        	
2.Orbital Sarcoidosis Presenting as Diffuse Swelling of the Lower Eyelid.
Korean Journal of Ophthalmology 2013;27(1):52-54
		                        		
		                        			
		                        			The author reports a case of orbital Sarcoidosis in a 70-year-old female that initially presented as diffuse swelling of the lower eyelid. The patient complained of painless swelling of the left lower lid without palpable mass, and a computerized tomography (CT) scan of the orbit was unremarkable. A serum angiotensin converting enzyme level was elevated, and hilar lymphadenopathy was noted on the chest CT. The patient underwent surgical debulking for histologic confirmation, which led to a final diagnosis of sarcoidosis involving the orbital fat. Unexplained chronic eyelid swelling without a mass should be considered a possible ophthalmic manifestation of orbital sarcoidosis.
		                        		
		                        		
		                        		
		                        			Aged
		                        			;
		                        		
		                        			Biopsy
		                        			;
		                        		
		                        			Diagnosis, Differential
		                        			;
		                        		
		                        			Edema/diagnosis/*etiology
		                        			;
		                        		
		                        			Eyelid Diseases/diagnosis/*etiology
		                        			;
		                        		
		                        			Eyelids/*pathology
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Orbital Diseases/*complications/diagnosis
		                        			;
		                        		
		                        			Sarcoidosis/*complications/diagnosis
		                        			;
		                        		
		                        			Tomography, X-Ray Computed
		                        			
		                        		
		                        	
3.Nasal NK/T cell lymphoma with outstanding performance of ocular symptoms.
Lei LIU ; Yulin ZHAO ; Jia WANG ; Fei MA
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2012;26(17):786-788
		                        		
		                        			OBJECTIVE:
		                        			To investigate the clinical features and misdiagnosis of nasal NK/T cell lymphoma with outstanding performance in ocular symptoms.
		                        		
		                        			METHOD:
		                        			Clinical data of 11 patients who had nasal NK/T cell lymphoma with the outstanding performances in ocular symptoms during 2009 to 2011 were retrospectively analyzed.
		                        		
		                        			RESULT:
		                        			The rate of misdiagnosis in the first diagnosis and first pathological diagnosis were 72.7% and 27.3% respectively. Nasal NK/T cell lymphoma with obvious ocular symptoms developed quickly and had almost special imaging findings.
		                        		
		                        			CONCLUSION
		                        			Nasal NK/T cell lymphoma with outstanding performance of ocular symptoms can be easily misdiagnosed. Comprehensive consideration of the clinical features, imaging findings and pathological examination do help to make accurate diagnosis early.
		                        		
		                        		
		                        		
		                        			Adolescent
		                        			;
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Aged
		                        			;
		                        		
		                        			Aged, 80 and over
		                        			;
		                        		
		                        			Child
		                        			;
		                        		
		                        			Child, Preschool
		                        			;
		                        		
		                        			Diagnostic Errors
		                        			;
		                        		
		                        			Exophthalmos
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			etiology
		                        			;
		                        		
		                        			Eyelid Diseases
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			etiology
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Lymphoma, Extranodal NK-T-Cell
		                        			;
		                        		
		                        			complications
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			Lymphoma, Non-Hodgkin
		                        			;
		                        		
		                        			complications
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Nose Neoplasms
		                        			;
		                        		
		                        			complications
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			Retrospective Studies
		                        			;
		                        		
		                        			Young Adult
		                        			
		                        		
		                        	
4.Eyelid swelling and lucency in the skull radiograph.
Annals of the Academy of Medicine, Singapore 2009;38(10):928-928
		                        		
		                        		
		                        		
		                        			Child
		                        			;
		                        		
		                        			Edema
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			etiology
		                        			;
		                        		
		                        			Emphysema
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			etiology
		                        			;
		                        		
		                        			Ethmoid Bone
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			injuries
		                        			;
		                        		
		                        			Eyelid Diseases
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			etiology
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Orbit
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			Orbital Diseases
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			pathology
		                        			;
		                        		
		                        			Radiography
		                        			;
		                        		
		                        			Skull
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			pathology
		                        			;
		                        		
		                        			Skull Fractures
		                        			;
		                        		
		                        			complications
		                        			;
		                        		
		                        			diagnostic imaging
		                        			
		                        		
		                        	
5.Upper Eyelid Retraction After Periorbital Trauma.
Korean Journal of Ophthalmology 2008;22(4):255-258
		                        		
		                        			
		                        			We report four unusual cases of upper eyelid retraction following periorbital trauma. Four previously healthy patients were evaluated for unilateral upper eyelid retraction following periorbital trauma. A 31-year-old man (Case 1) and a 24-year-old man (Case 2) presented with left upper eyelid retraction which developed after blow-out fractures, a 44-year-old woman (Case 3) presented with left upper eyelid retraction secondary to a periorbital contusion that occurred one week prior, and a 56-year-old man (Case 4) presented with left upper eyelid retraction that developed 1 month after a lower canalicular laceration was sustained during a traffic accident. The authors performed a thyroid function test and orbital computed tomography (CT) in all cases. Thyroid function was normal in all patients, CT showed an adhesion of the superior rectus muscle and superior oblique muscle in the first case and diffuse thickening of the superior rectus muscle and levator complex in the third case. CT showed no specific findings in the second or fourth cases. Upper eyelid retraction due to superior complex adhesion can be considered one of the complications of periorbital trauma.
		                        		
		                        		
		                        		
		                        			Accidents, Traffic
		                        			;
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Eye Injuries/*complications/surgery
		                        			;
		                        		
		                        			Eyelid Diseases/*etiology/radiography
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Lacerations/complications/surgery
		                        			;
		                        		
		                        			Lacrimal Apparatus/*injuries
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Oculomotor Muscles
		                        			;
		                        		
		                        			Orbital Fractures/*complications/surgery
		                        			;
		                        		
		                        			Tomography, X-Ray Computed
		                        			
		                        		
		                        	
6.Diagnosis and management of lipogranuloma of the eyelids from nasal endoscopic surgery.
Yunkai GUO ; Anquan PENG ; Dan XIE ; Youzhong LI ; Jihao REN ; Manyi XIAO ; Songqing FAN ; Xinming YANG ; Weijing WU ; Dinghua XIE
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2007;21(8):340-343
		                        		
		                        			OBJECTIVE:
		                        			To enhance the safety of nasal endoscopic surgery and decrease its complications of eyes.
		                        		
		                        			METHOD:
		                        			Three patients of chronic rhinosinusitis and nasal polyposis with lipogranulomas of the eyelids after nasal endoscopic surgery and nasal packing of petrolatum gauze were reported and analyzed, and their treatment results were presented during the last 2 years.
		                        		
		                        			RESULT:
		                        			The medial orbital wall injury occurred in all three patients during endoscopic sinus surgery. The patients developed an ipsilateral periocular swelling, eyelid hematoma and palpebral conjunctival edema during 2 to 3 hours after surgery. Nasal packs petrolatum gauze were removed 10-24 hours after surgery. The patients were discharged from hospital when periorbital swelling and eyelid ecchymoma disappeared, and nasal cavity obstruction was improved 6 to 8 days after surgery. The swelling and nodular mass of ipsilateral eyelids (one in left upper eyelid and two in right lower eyelid) were found 12-15 days after surgery, and their eye movement and eyesight were normal. Antibiotic and corticosteroid were administered for 3 4 weeks with only improvement in eyelid swelling. These masses of eyelids were completely excised through palpebral margin 1-6 months after surgery. The histopathological examination of the surgical specimens showed lipogranuloma. No recurrence and symptom of the eyes had been observed during 4-18 months follow up.
		                        		
		                        			CONCLUSION
		                        			The lipogranuloma of the eyelid is a rare and late complication after nasal endoscopic surgery and nasal packing with vaspetrolatum gauze. The medial orbital wall injury and bleeding during surgery, and vaseline of nasal packing permeated into the eyelid are the direct causes of this complication. The application of petrolatum gauze should be avoided when the medial orbital wall trauma is identified. The complete excision of granulomas is a best effective therapy.
		                        		
		                        		
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Endoscopy
		                        			;
		                        		
		                        			adverse effects
		                        			;
		                        		
		                        			Eyelid Diseases
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			etiology
		                        			;
		                        		
		                        			therapy
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Granuloma
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			etiology
		                        			;
		                        		
		                        			therapy
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Postoperative Complications
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			therapy
		                        			
		                        		
		                        	
7.A Case of Scar Sarcoidosis of The Eyelid.
Korean Journal of Ophthalmology 2006;20(4):238-240
		                        		
		                        			
		                        			PURPOSE: We report the case of a patient with scar sarcoidosis that developed along a previous eyelid scar. There was no evidence of ocular or systemic sarcoidosis. METHODS: A 29-year-old man presented with a mass on his right eyelid that had been present for two month. On ocular examination an erythematous, firm, and non-tender mass was diffusely palpable along the upper and lower eyelid scar. We performed an incisional biopsy of the lower lid mass. RESULTS: Histopathologic examination of the mass revealed numerous, noncaseating granulomas with multi-nucleated giant cells. The giant cells contained asteroid bodies and calcium oxalate crystals characteristic of sarcoidosis, although the patient had no other evidence of systemic sarcoidosis. The mass in the upper lid disappeared after intralesional triamcinolone injections. CONCLUSIONS: This case represents a rare occurrence of sarcoidosis that arose in an old eyelid scar. Scar sarcoidosis should be considered in the differential diagnosis of an unusual mass in a scar.
		                        		
		                        		
		                        		
		                        			Triamcinolone/administration & dosage
		                        			;
		                        		
		                        			Sarcoidosis/drug therapy/etiology/*pathology
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Injections, Intralesional
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Glucocorticoids/administration & dosage
		                        			;
		                        		
		                        			Follow-Up Studies
		                        			;
		                        		
		                        			Eyelids/injuries
		                        			;
		                        		
		                        			Eyelid Diseases/drug therapy/etiology/*pathology
		                        			;
		                        		
		                        			Eye Injuries/complications
		                        			;
		                        		
		                        			Diagnosis, Differential
		                        			;
		                        		
		                        			Cicatrix/complications/*pathology
		                        			;
		                        		
		                        			Biopsy
		                        			;
		                        		
		                        			Adult
		                        			
		                        		
		                        	
8.Two surgical methods to modify upper eyelid retraction with thyroid associated-ophthalmopathy.
Chinese Journal of Plastic Surgery 2006;22(5):358-361
OBJECTIVETo evaluate the treatment effect of the two surgical methods for upper eyelid retraction with thyroid associated-ophthalmopathy.
METHODSTwenty-two patients (32 eyes) with inactive thyroid associated-ophthalmopathy were divided into 2 groups (11 for each group) randomly. 11 patients (18 eyes) in the group A were treated by central tenotomy of levator aponeurosis. Another 11 patients (14 eyes) in the group B were treated by lengthening of Mullers' muscle combined with levator muscle. The treatment effect was investigated in 6-month follow-up study.
RESULTSAll of the patients were improved with the two surgical methods, which there was very significant difference before and after the treatments (P < 0.01), but not between the two surgical methods (P > 0.05) by statistical analysis. There was recurrent retracting in 4 patients (6 eyes) of group A and in 1 patient (1 eye) of group B, which there was significant difference between the two groups (P < 0.05) by Chi-square test. None of the patients was overcorrected.
CONCLUSIONSThe two methods are both effective and safe in correcting upper eyelid retraction. The rate of recurrent retracting is lower in lengthening of Mullers' muscle combined with levator muscle than that in central tenotomy of levator aponeurosis.
Blepharoplasty ; methods ; Eyelid Diseases ; etiology ; surgery ; Female ; Graves Ophthalmopathy ; surgery ; Humans ; Male ; Oculomotor Muscles ; surgery
9.Inadvertent Ocular Perforation during Lid Anesthesia for Hordeolum Removal.
Jun Heon KIM ; Sun Mo YANG ; Hyo Myung KIM ; Jaeryung OH
Korean Journal of Ophthalmology 2006;20(3):199-200
		                        		
		                        			
		                        			PURPOSE: Ocular perforation during lid anesthesia is rarely reported. We describe here a case of inadvertent corneal perforation and traumatic cataract that occurred during lid anesthesia in a procedure for hordeolum removal. METHODS: A 33-year-old woman presented with a sudden visual loss of her left eye. She had undergone hordeolum removal the day before at a local clinic. On ophthalmologic examination, the cornea was perforated and the lens cortex was extruded into the anterior chamber. After cataract removal and IOL implantation, antibiotics were injected into the vitreous. RESULTS: Her final visual acuity of the left eye was 20/20. Postoperative specular microscopic examination revealed a normal-range endothelial cell count, coefficient of variation, and hexagonality despite the intracameral lidocaine injection. CONCLUSIONS: Anesthetic injection of an infected lid should be done with great caution. Although there are possibilities of corneal endothelial toxicity and endophthalmitis in case of intracameral lidocaine injection through the infected lid, yet proper management may save the patient's vision without complications.
		                        		
		                        		
		                        		
		                        			Lidocaine/administration & dosage
		                        			;
		                        		
		                        			Lens Implantation, Intraocular
		                        			;
		                        		
		                        			Lens Capsule, Crystalline/injuries
		                        			;
		                        		
		                        			Injections/adverse effects
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Hordeolum/*surgery
		                        			;
		                        		
		                        			Follow-Up Studies
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Eyelids
		                        			;
		                        		
		                        			Eyelid Diseases/*surgery
		                        			;
		                        		
		                        			Eye Injuries, Penetrating/diagnosis/*etiology/surgery
		                        			;
		                        		
		                        			Diagnosis, Differential
		                        			;
		                        		
		                        			Cornea/injuries
		                        			;
		                        		
		                        			Cataract Extraction
		                        			;
		                        		
		                        			Anesthetics, Local/administration & dosage
		                        			;
		                        		
		                        			Anesthesia, Local/*adverse effects
		                        			;
		                        		
		                        			Adult
		                        			
		                        		
		                        	
10.Correction of Superior Sulcus Deformity and Enophthalmos with Porous High-density Polyethylene Sheet in Anophthalmic Patients.
Byeung Hun CHOI ; Sang Hyeok LEE ; Wha Sun CHUNG
Korean Journal of Ophthalmology 2005;19(3):168-173
		                        		
		                        			
		                        			PURPOSE: Superior sulcus deformity is the main cosmetic problem in anophthalmic patients. Many methods of correcting enophthalmos have been reported, especially in patients with orbital wall fracture. The purpose of this study is to review the long term results of effectiveness in superior sulcus deformity correction by subperiosteal Medpor (R) sheet implantation in anophthalmic patients. METHODS: Subperiosteal Medpor (R) sheets were used in 11 eyes of 11 anophthalmic patients. To estimate the effectiveness, photographs were taken and exophthalmometric value with their own prosthesis using Hertel exophthalmometer was measured in all patients before and after surgery. RESULTS: The overall cosmetic results in superior sulcus deformity were 'excellent' in 3 (27.3%), 'good' in 6 (54.5%), 'fair' in 2 (18.2%). The overall results in enophthalmos were 'excellent' in 3 (27.2%), 'markedly improved' in 4 (36.4%), 'slightly improved' in 4 (36.4%). Most patients had a marked increase in orbital volume, except two patients. They received irradiation treatment in early childhood so showed unsatisfactory results in both superior sulcus deformity and enophthalmos. CONCLUSIONS: Subperiosteal Medpor (R) sheet implantation is considered to be a reliable and safe procedure without serious complication and with an excellent cosmetic results.
		                        		
		                        		
		                        		
		                        			*Surgical Mesh
		                        			;
		                        		
		                        			Surgery, Plastic
		                        			;
		                        		
		                        			Retrospective Studies
		                        			;
		                        		
		                        			*Polyethylene
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Eyelid Diseases/*etiology/*surgery
		                        			;
		                        		
		                        			Enophthalmos/*etiology/*surgery
		                        			;
		                        		
		                        			Child
		                        			;
		                        		
		                        			Anophthalmos/*complications
		                        			;
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Adolescent
		                        			
		                        		
		                        	
            
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