2.Effects of Systemic Administration of Dexmedetomidine on Intraocular Pressure and Ocular Perfusion Pressure during Laparoscopic Surgery in a Steep Trendelenburg Position: Prospective, Randomized, Double-Blinded Study.
Jin JOO ; Hyunjung KOH ; Kusang LEE ; Jaemin LEE
Journal of Korean Medical Science 2016;31(6):989-996
Increased intraocular pressure (IOP) during surgery is a risk factor for postoperative ophthalmological complications. We assessed the efficacy of systemically infused dexmedetomidine in preventing the increase in IOP caused by a steep Trendelenburg position, and evaluated the influence of underlying hypertension on IOP during surgery. Sixty patients undergoing laparoscopic surgery in a steep Trendelenburg position were included. Patients in the dexmedetomidine group received a 1.0 µg/kg IV loading dose of dexmedetomidine before anesthesia, followed by an infusion of 0.5 µg/kg/hr throughout the operation. Patients in the saline group were infused with the same volume of normal saline. IOP and ocular perfusion pressure (OPP) were measured 16 times pre- and intraoperatively. In the saline group, IOP increased in the steep Trendelenburg position, and was 11.3 mmHg higher at the end of the time at the position compared with the baseline value (before anesthetic induction). This increase in IOP was attenuated in the dexmedetomidine group, for which IOP was only 4.2 mmHg higher (P < 0.001 vs. the saline group). The steep Trendelenburg position was associated with a decrease in OPP; the degree of decrease was comparable for both groups. In intragroup comparisons between patients with underlying hypertension and normotensive patients, the values of IOP at every time point were comparable. Dexmedetomidine infusion attenuated the increase in IOP during laparoscopic surgery in a steep Trendelenburg position, without further decreasing the OPP. Systemic hypertension did not seem to be associated with any additional increase in IOP during surgery. (Registration at the Clinical Research Information Service of Korea National Institute of Health ID: KCT0001482)
Aged
;
Dexmedetomidine/administration & dosage/*pharmacology
;
Double-Blind Method
;
Eye Diseases/surgery
;
Female
;
Head-Down Tilt
;
Humans
;
Hypnotics and Sedatives/administration & dosage/pharmacology
;
Intraocular Pressure/*drug effects
;
Intraoperative Complications/drug therapy/prevention & control
;
Laparoscopy
;
Male
;
Middle Aged
;
Prospective Studies
;
Risk Factors
;
Tonometry, Ocular
;
Treatment Outcome
3.Ocular Manifestations of Acquired Immunodeficiency Syndrome.
Young Shin KIM ; Hae Jung SUN ; Tae Hyong KIM ; Kui Dong KANG ; Sung Jin LEE
Korean Journal of Ophthalmology 2015;29(4):241-248
PURPOSE: To investigate the patterns and risk factors of the ocular manifestations of acquired immunodeficiency syndrome (AIDS) and their correlation with CD4+ count in the era of highly active antiretroviral therapy (HAART). METHODS: This retrospective study examined 127 AIDS patients who presented to Soonchunhyang University Hospital. Data were collected from patient interviews, clinical examinations, and laboratory investigations. Ophthalmologic examinations included the best-corrected visual acuity, intraocular pressure, anterior segment and adnexal examination, and dilated fundus examination. RESULTS: Of the 127 patients with AIDS, 118 were on HAART and 9 were not. The mean CD4+ count was 266.7 +/- 209.1 cells/microL. There were ocular manifestations in 61 patients (48.0%). The incidence of anterior segment manifestations was higher than posterior segment manifestations at 28.3% and 19.7%, respectively. The mean CD4+ count was significantly (p < 0.05) lower in the patients with posterior versus anterior segment ocular manifestations. The most common ocular manifestation was retinal microvasculopathy (15.0%), followed by keratoconjunctivitis sicca (14.2%), conjunctival microvasculopathy (9.4%), cytomegalovirus retinitis (3.1%), herpes zoster ophthalmicus (2.4%), and blepharitis (1.6%). Retinal microvasculopathy and cytomegalovirus retinitis were common in patients with CD4+ counts <200 cells/microL, while keratoconjunctivitis sicca and conjunctival microvasculopathy were common in patients with CD4+ counts of 200 to 499 cells/microL. There was a significant (p < 0.05) association between ocular manifestation and CD4+ count or age. CONCLUSIONS: The introduction of HAART has changed the landscape of ocular presentations in patients with AIDS. In this study, anterior segment and external ocular manifestations occurred more frequently than posterior segment manifestations. Also, the mean CD4+ count was significantly lower in patients with posterior segment ocular manifestations versus anterior segment ocular manifestations. We found that CD4+ count and age >35 years were independent risk factors for developing ocular manifestations.
Acquired Immunodeficiency Syndrome/*complications
;
Adult
;
Aged
;
Eye Diseases/diagnosis/epidemiology/*etiology
;
Female
;
Humans
;
Incidence
;
Male
;
Middle Aged
;
Republic of Korea/epidemiology
;
Retrospective Studies
;
Risk Factors
;
Visual Acuity
;
Young Adult
4.Successful Treatment of Infectious Scleritis by Pseudomonas aeruginosa with Autologous Perichondrium Graft of Conchal Cartilage.
Woong Sun YOO ; Che Ron KIM ; Byung Jae KIM ; Seong Ki AHN ; Seong Wook SEO ; Ji Myong YOO ; Seong Jae KIM
Yonsei Medical Journal 2015;56(6):1738-1741
Infectious scleritis by Pseudomonas aeruginosa is a well-known vision-threatening disease. In particular, scleral trauma following pterygium surgery may increase the risk of sclera inflammation. Surgical debridement and repair is necessary in patients who do not respond to medical treatments, such as topical and intravenous antibiotics. We reports herein the effectiveness of an autologous perichondrium conchal cartilage graft for infectious scleritis caused by Pseudomonas aeruginosa. This procedure was performed on four eyes of four patients with infectious scleritis who had previously undergone pterygium surgery at Gyeongsang National University Hospital (GNUH), Jinju, Korea from December 2011 to May 2012. Pseudomonas aeruginosa was identified in cultures of necrotic scleral lesion before surgery. The conchal cartilage perichondrium graft was transplanted, and a conjunctival flap was created on the scleral lesion. The autologous perichondrium conchal cartilage graft was successful and visual outcome was stable in all patients, with no reports of graft failure or infection recurrence. In conclusion, autologous perichondrium conchal cartilage graft may be effective in surgical management of Pseudomonal infectious scleritis when non-surgical medical treatment is ineffective. Further studies in larger, diverse populations are warranted to establish the effectiveness of the procedure.
Anti-Bacterial Agents/therapeutic use
;
Autografts
;
Cartilage/surgery
;
Communicable Diseases
;
Debridement
;
Eye Infections, Bacterial/etiology/*therapy
;
Female
;
Humans
;
Ophthalmologic Surgical Procedures
;
Postoperative Complications
;
Pseudomonas Infections/microbiology/*therapy
;
Pseudomonas aeruginosa/*isolation & purification
;
Pterygium/surgery
;
Republic of Korea
;
Sclera/*surgery/transplantation
;
Scleritis/microbiology/*therapy
;
Surgical Wound Infection/microbiology/*therapy
;
Transplantation, Autologous
;
Treatment Outcome
5.Long-term Surgical Outcomes of the Multi-purpose Conical Porous Synthetic Orbital Implant.
Min Ji KANG ; Su Kyung JUNG ; Won Kyung CHO ; Ji Sun PAIK ; Suk Woo YANG
Korean Journal of Ophthalmology 2015;29(5):294-300
PURPOSE: We present clinical results of the use of the multipurpose conical porous synthetic orbital implant (MCOI) in surgical procedures of evisceration, enucleation, and secondary enucleation in ophthalmology patients. METHODS: A retrospective review was performed of 59 eyes in which conical implants were used, including 36 cases of eviscerations, 11 enucleations, and 9 secondary enucleations. In all of the cases, the follow-up period was greater than six months between 2004 and 2013. The results focus on documenting surgical findings, as well as postoperative complications among patients. RESULTS: Superior sulcus deformities were found in six eyes (10.2% of conical implant patients), and two eyes received additional surgical interventions to correct the deformities (3.4%). Blepharoptosis was found in four eyes (6.8%), two of which received upper eyelid blepharoplasty (3.4%). Fornix shortening was reported in only one eye (1.7%). Forty-one eyes had a satisfactory cosmetic appearance after the final prosthetic fitting of conical implants (69.5%). The most frequent postoperative complication was orbital implant exposure, which seemed to occur when the preoperative status of the conjunctiva, Tenon's capsule, and sclera preservation were poor in the eyes of the patients. CONCLUSIONS: There was a lower incidence of blepharoptosis and fornix shortening with the MCOI in comparison to spherical implants, while the incidence of orbital implant exposure was similar with the MCOI in comparison to other types of orbital implants. In addition, the MCOI may have advantages with respect to postoperative cosmetic outcomes.
Adult
;
Eye Diseases/*surgery
;
*Eye Enucleation
;
*Eye Evisceration
;
Female
;
Follow-Up Studies
;
Humans
;
Incidence
;
Male
;
Middle Aged
;
*Orbital Implants
;
Postoperative Complications/*epidemiology
;
Prosthesis Implantation/*methods
;
Republic of Korea/epidemiology
;
Retrospective Studies
;
Time Factors
;
Treatment Outcome
6.Case Reports of Lacrimal Sac Tumors Discovered in Patients with Persistent Epiphora Following Dacryocystorhinostomy.
Ka Hyun LEE ; Sun Hyup HAN ; Jin Sook YOON
Korean Journal of Ophthalmology 2015;29(1):66-67
No abstract available.
Aged
;
Biopsy
;
Carcinoma, Squamous Cell/diagnosis/*etiology
;
Dacryocystorhinostomy/*adverse effects
;
Eye Neoplasms/diagnosis/*etiology
;
Female
;
Humans
;
Lacrimal Apparatus/pathology/*surgery
;
Lacrimal Apparatus Diseases/diagnosis/*etiology
;
*Postoperative Complications
;
Tomography, X-Ray Computed
7.Clinical features of ocular symptom in patients with allergic rhinitis.
Juan MENG ; Yafeng LIU ; Hongting ZHANG ; Xuelian YI ; Shixi LIU
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2014;28(17):1321-1325
OBJECTIVE:
To investigate the clinical characteristics of ocular symptoms in patients with allergic rhinitis (AR) and the impact of the ocular symptoms on patients' quality of life.
METHOD:
AR patients' history and clinical data were collected and analyzed. One hundred cases were extracted from adult patients with and without ocular symptoms in each group and their quality of life were evaluated using rhino-conjunctivitis quality of life questionnaire (RQLQ).
RESULT:
Totally 1119 cases were collected and 859 cases had ocular symptoms. Of the patients with ocular symptoms, 582 cases were mild, 234 cases were moderate, 43 cases were severe. Eye itching was the most common symptom, followed by tears, hyperemia and swelling. Patients with ocular symptoms had longer disease history than non ocular symptom group (P < 0.05). There was a positive correlation between ocular and nasal symptoms (P < 0.01); patients with ocular symptoms had more severe nasal symptoms than patients without ocular problems; while patients with moderate to severe AR had more severe ocular symptoms than mild AR patients (P < 0.01). Female patients had higher incidence (P < 0.05) and ocular symptoms score (P < 0.05) than male. Children less than 10 years old had a relative lower incidence and score of ocular symptoms. While the incidence and score had an increasing trend for patients older than fifty. There was no difference regarding the type and number of allergen in the patients with and without ocular symptom. Moreover, patients with ocular symptoms had higher scores in the domains of non-nose/eye symptoms, practical problems, ocular symptoms, emotional function and total score in RQLQ than patients without ocular symptom.
CONCLUSION
It was common for the AR patients to have ocular symptoms, and ocular symptoms had obvious influence on the patients' quality of life. So controlling of the ocular symptoms should not be ignored during the diagnosis and treatment of AR.
Adolescent
;
Adult
;
Allergens
;
Child
;
Eye Diseases
;
etiology
;
Female
;
Humans
;
Male
;
Quality of Life
;
Rhinitis, Allergic
;
complications
;
Rhinitis, Allergic, Perennial
;
complications
;
Surveys and Questionnaires
8.17 cases of mucosal antral cyst with main symptoms of eye pain.
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2014;28(2):93-94
OBJECTIVE:
To draw the attention to mucosal antral cyst, thus reduce the probability of missed diagnosis and missed treatment by retrospectively analyzing 17 cases of eye pain patients with no obvious nasal symptoms in our department from January 2003 to September 2011.
METHOD:
All patients were performed ophthalmologic examination including eye position, eyesight, refraction, visual field, intraocular pressure and fundus examination, and the results showed that all of them had no eye disease. After excluding the deviation of nasal septum, concha bullosa and Haller gas room, CT scanning of paranasal sinus showed the maxillary sinus cyst. The patients were operated by nasal endoscope through joint path of middle meatus or inferior meatus and given antibiotics after operation. The nasal cavity packing was removed 24 hours postoperatively and the patients were discharged from hospital a week later. All the patients continued using intranasal corticosteroids and were followed up for half a year to observe whether the eye pain disappeared or recurred, when various processing was given to the surgical cavity with the help of nasal endoscope.
RESULT:
Among the 17 cases, 14 cases of eye pain disappeared after the operation, and the remaining 3 patients got symptomatic relief without recurrence during the follow-up period.
CONCLUSION
Mucosal antral cyst can cause eye pain. After excluding eye disease, once we diagnosed patients for mucosal antral cyst and the routine application of corticosteroids treatment was proved to be invalid, we should take operation treatment as early as possible, regardless of the size and location of the cysts.
Adolescent
;
Adult
;
Cysts
;
complications
;
diagnosis
;
Eye Pain
;
diagnosis
;
etiology
;
Female
;
Humans
;
Male
;
Maxillary Sinus
;
Middle Aged
;
Mucous Membrane
;
Paranasal Sinus Diseases
;
complications
;
diagnosis
;
Retrospective Studies
;
Young Adult
9.Ocular complications following surgery of chronic suppurative otitis media.
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2014;29(8):726-732
OBJECTIVE:
To investigate the rarely reported ocular complications following surgery of chronic suppurative otitis media (CSOM) and explore the possible mechanisms.
METHOD:
The clinical data of 4,012 cases of CSOM treated with surgery were analyzed retrospectively, including age, sex, operation time, surgical approach, time of ocular symptoms presentation, duration of ocular symptoms, treatment and prognosis.
RESULT:
Among the 4,012 cases, 109 patients (2.72%) developed ocular complication, of which 68.81% (75/109) suffered from blurred vision, 24.77% (27/109) presented only erythema on eyelids or mild periorbital edema, 4.59% (5/109) had erythema on eyelids with periorbital edema, and 1.83% (2/109) complained of periorbital ecchymosis and edema. All of these complications recovered themselves without any sequela.
CONCLUSION
Ocular complications following surgery of CSOM are rarely reported. Pre-auricular incision and fascia harvesting, turbulence of venous and lymphatic drainage and preseptal cellulitis might be the risk factors. Blurred vision might be associated with eye injury during surgery and the use of anticholinergic agent.
Chronic Disease
;
Eye Diseases
;
Humans
;
Otitis Media, Suppurative
;
surgery
;
Postoperative Complications
;
Retrospective Studies
;
Risk Factors
10.Relationship of Hypertropia and Excyclotorsion in Superior Oblique Palsy.
Jung Jin LEE ; Ko I CHUN ; Seung Hee BAEK ; Ungsoo Samuel KIM
Korean Journal of Ophthalmology 2013;27(1):39-43
PURPOSE: To evaluate the correlation between hypertropia and excyclotorsion in acquired superior oblique palsy (SOP). METHODS: Thirty-one patients with acquired unilateral SOP were recruited for this study. The torsional angle of each patient was assessed via one objective method (fundus photography) and two subjective methods (double Maddox rod test and major amblyoscope). The patient population was divided into two groups (concordance group, n = 19 and discordance group, n = 12) according to the correspondence between the hypertropic eye (paralytic eye) and the more extorted eye (non-fixating eye), which was evaluated by fundus photography. RESULTS: The mean value of objective torsion was 5.09degrees +/- 3.84degrees. The subjective excyclotorsion degrees were 5.18degrees +/- 4.11degrees and 3.65degrees +/- 1.93degrees as measured by double Maddox rod test and major amblyoscope, respectively. Hypertropia and the excyclotorsional angle did not differ significantly between the groups (p = 0.257). Although no correlation was found in the discordance group, the concordance group showed a significant and positive correlation between hypertropia and excyclotorsion (p = 0.011). CONCLUSIONS: Torsional deviation was not related to hypertropia. However, in the concordance patients in whom the hypertropic eye showed excyclotorsion, a significant positive correlation was found between hypertropia and excyclotorsion.
Adolescent
;
Adult
;
Aged
;
Child
;
Diagnostic Techniques, Ophthalmological
;
Eye Movements
;
Female
;
Follow-Up Studies
;
Humans
;
Male
;
Middle Aged
;
Oculomotor Muscles/*physiopathology
;
Ophthalmologic Surgical Procedures/*methods
;
Ophthalmoplegia/*etiology/physiopathology/surgery
;
Retrospective Studies
;
Strabismus/*etiology/physiopathology/surgery
;
Treatment Outcome
;
Trochlear Nerve Diseases/*complications/physiopathology/surgery
;
Young Adult

Result Analysis
Print
Save
E-mail