1.Present and future of oculoplasty.
Journal of the Korean Medical Association 2017;60(9):739-745
		                        		
		                        			
		                        			Ophthalmic plastic and reconstructive surgery combines the precision of ophthalmic microsurgery with plastic and reconstructive surgical principles, allowing for subspecialized care of the eyelid, orbital, and lacrimal system. A foundation in ophthalmology allows the oculoplastic surgeon's knowledge and skills to safely and successfully protect the globe while achieving good functional and aesthetic results. Oculoplasty emerged following World War II, in which a high rate of ophthalmic and oculoplastic trauma occurred. Following this, more structured and specialized studies dedicated to clinical and surgical management led to the development of a highly specific and rapidly growing sub-specialty dedicated to eyelid, lacrimal, and orbital care. Stem cell treatments in oculoplasty has been spanned a wide array of subfields, ranging from reconstruction of the eyelid to the generation of artificial lacrimal glands and oncological therapeutics. Tissue engineering represents the future of regenerative and reconstructive medicine, with significant potential applications in ophthalmic plastic surgery. Difficulty remains in disease modeling for various disorders, owing to genetic and functional variation across patients as well as the complexity of several diseases. Progressive advances in the understanding of the immunopathogenesis of diseases such as thyroid eye disease and lacrimal gland carcinoma continue to spur clinical trials utilizing targeted therapies to enhance treatment outcomes. Continued investigation of the molecular mechanisms of disease will expand potential treatments. In the future, public awareness and interest in the field of oculoplasty will further grow, and personalized and optimized treatment will become a cornerstone of modern medicine.
		                        		
		                        		
		                        		
		                        			Eye Diseases
		                        			;
		                        		
		                        			Eyelids
		                        			;
		                        		
		                        			Graves Ophthalmopathy
		                        			;
		                        		
		                        			History, Modern 1601-
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Lacrimal Apparatus
		                        			;
		                        		
		                        			Microsurgery
		                        			;
		                        		
		                        			Ophthalmology
		                        			;
		                        		
		                        			Orbit
		                        			;
		                        		
		                        			Plastics
		                        			;
		                        		
		                        			Stem Cells
		                        			;
		                        		
		                        			Surgery, Plastic
		                        			;
		                        		
		                        			Thyroid Gland
		                        			;
		                        		
		                        			Tissue Engineering
		                        			;
		                        		
		                        			World War II
		                        			
		                        		
		                        	
2.Hereditary vitreous degeneration muddy: report of ten cases.
Zhixin SHEN ; Enfang GAO ; Wenqing WENG ; Weiling LUO
Journal of Zhejiang University. Medical sciences 2016;45(6):636-640
		                        		
		                        			
		                        			Hereditary vitreous degeneration muddy is rare in clinic. Here we report ten cases (thirteen eyes) of hereditary vitreous degeneration muddy from two families. All patients presented with vitreous opacity, and the textures appeared tough and tensile. Two cases had concurrent detachment of rhegmatogenous retina. HE staining showed red changeableness, and methyl violet staining appeared purple. All patients received vitrectomy with traditional Chinese medicine treatment, and got satisfactory efficacy.
		                        		
		                        		
		                        		
		                        			Eye Diseases, Hereditary
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			pathology
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			therapy
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Medicine, Chinese Traditional
		                        			;
		                        		
		                        			Retinal Detachment
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Vitrectomy
		                        			;
		                        		
		                        			Vitreous Body
		                        			;
		                        		
		                        			pathology
		                        			;
		                        		
		                        			surgery
		                        			
		                        		
		                        	
3.Effects of Systemic Administration of Dexmedetomidine on Intraocular Pressure and Ocular Perfusion Pressure during Laparoscopic Surgery in a Steep Trendelenburg Position: Prospective, Randomized, Double-Blinded Study.
Jin JOO ; Hyunjung KOH ; Kusang LEE ; Jaemin LEE
Journal of Korean Medical Science 2016;31(6):989-996
		                        		
		                        			
		                        			Increased intraocular pressure (IOP) during surgery is a risk factor for postoperative ophthalmological complications. We assessed the efficacy of systemically infused dexmedetomidine in preventing the increase in IOP caused by a steep Trendelenburg position, and evaluated the influence of underlying hypertension on IOP during surgery. Sixty patients undergoing laparoscopic surgery in a steep Trendelenburg position were included. Patients in the dexmedetomidine group received a 1.0 µg/kg IV loading dose of dexmedetomidine before anesthesia, followed by an infusion of 0.5 µg/kg/hr throughout the operation. Patients in the saline group were infused with the same volume of normal saline. IOP and ocular perfusion pressure (OPP) were measured 16 times pre- and intraoperatively. In the saline group, IOP increased in the steep Trendelenburg position, and was 11.3 mmHg higher at the end of the time at the position compared with the baseline value (before anesthetic induction). This increase in IOP was attenuated in the dexmedetomidine group, for which IOP was only 4.2 mmHg higher (P < 0.001 vs. the saline group). The steep Trendelenburg position was associated with a decrease in OPP; the degree of decrease was comparable for both groups. In intragroup comparisons between patients with underlying hypertension and normotensive patients, the values of IOP at every time point were comparable. Dexmedetomidine infusion attenuated the increase in IOP during laparoscopic surgery in a steep Trendelenburg position, without further decreasing the OPP. Systemic hypertension did not seem to be associated with any additional increase in IOP during surgery. (Registration at the Clinical Research Information Service of Korea National Institute of Health ID: KCT0001482)
		                        		
		                        		
		                        		
		                        			Aged
		                        			;
		                        		
		                        			Dexmedetomidine/administration & dosage/*pharmacology
		                        			;
		                        		
		                        			Double-Blind Method
		                        			;
		                        		
		                        			Eye Diseases/surgery
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Head-Down Tilt
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Hypnotics and Sedatives/administration & dosage/pharmacology
		                        			;
		                        		
		                        			Intraocular Pressure/*drug effects
		                        			;
		                        		
		                        			Intraoperative Complications/drug therapy/prevention & control
		                        			;
		                        		
		                        			Laparoscopy
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Prospective Studies
		                        			;
		                        		
		                        			Risk Factors
		                        			;
		                        		
		                        			Tonometry, Ocular
		                        			;
		                        		
		                        			Treatment Outcome
		                        			
		                        		
		                        	
4.Long-term Surgical Outcomes of the Multi-purpose Conical Porous Synthetic Orbital Implant.
Min Ji KANG ; Su Kyung JUNG ; Won Kyung CHO ; Ji Sun PAIK ; Suk Woo YANG
Korean Journal of Ophthalmology 2015;29(5):294-300
		                        		
		                        			
		                        			PURPOSE: We present clinical results of the use of the multipurpose conical porous synthetic orbital implant (MCOI) in surgical procedures of evisceration, enucleation, and secondary enucleation in ophthalmology patients. METHODS: A retrospective review was performed of 59 eyes in which conical implants were used, including 36 cases of eviscerations, 11 enucleations, and 9 secondary enucleations. In all of the cases, the follow-up period was greater than six months between 2004 and 2013. The results focus on documenting surgical findings, as well as postoperative complications among patients. RESULTS: Superior sulcus deformities were found in six eyes (10.2% of conical implant patients), and two eyes received additional surgical interventions to correct the deformities (3.4%). Blepharoptosis was found in four eyes (6.8%), two of which received upper eyelid blepharoplasty (3.4%). Fornix shortening was reported in only one eye (1.7%). Forty-one eyes had a satisfactory cosmetic appearance after the final prosthetic fitting of conical implants (69.5%). The most frequent postoperative complication was orbital implant exposure, which seemed to occur when the preoperative status of the conjunctiva, Tenon's capsule, and sclera preservation were poor in the eyes of the patients. CONCLUSIONS: There was a lower incidence of blepharoptosis and fornix shortening with the MCOI in comparison to spherical implants, while the incidence of orbital implant exposure was similar with the MCOI in comparison to other types of orbital implants. In addition, the MCOI may have advantages with respect to postoperative cosmetic outcomes.
		                        		
		                        		
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Eye Diseases/*surgery
		                        			;
		                        		
		                        			*Eye Enucleation
		                        			;
		                        		
		                        			*Eye Evisceration
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Follow-Up Studies
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Incidence
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			*Orbital Implants
		                        			;
		                        		
		                        			Postoperative Complications/*epidemiology
		                        			;
		                        		
		                        			Prosthesis Implantation/*methods
		                        			;
		                        		
		                        			Republic of Korea/epidemiology
		                        			;
		                        		
		                        			Retrospective Studies
		                        			;
		                        		
		                        			Time Factors
		                        			;
		                        		
		                        			Treatment Outcome
		                        			
		                        		
		                        	
5.Successful Treatment of Infectious Scleritis by Pseudomonas aeruginosa with Autologous Perichondrium Graft of Conchal Cartilage.
Woong Sun YOO ; Che Ron KIM ; Byung Jae KIM ; Seong Ki AHN ; Seong Wook SEO ; Ji Myong YOO ; Seong Jae KIM
Yonsei Medical Journal 2015;56(6):1738-1741
		                        		
		                        			
		                        			Infectious scleritis by Pseudomonas aeruginosa is a well-known vision-threatening disease. In particular, scleral trauma following pterygium surgery may increase the risk of sclera inflammation. Surgical debridement and repair is necessary in patients who do not respond to medical treatments, such as topical and intravenous antibiotics. We reports herein the effectiveness of an autologous perichondrium conchal cartilage graft for infectious scleritis caused by Pseudomonas aeruginosa. This procedure was performed on four eyes of four patients with infectious scleritis who had previously undergone pterygium surgery at Gyeongsang National University Hospital (GNUH), Jinju, Korea from December 2011 to May 2012. Pseudomonas aeruginosa was identified in cultures of necrotic scleral lesion before surgery. The conchal cartilage perichondrium graft was transplanted, and a conjunctival flap was created on the scleral lesion. The autologous perichondrium conchal cartilage graft was successful and visual outcome was stable in all patients, with no reports of graft failure or infection recurrence. In conclusion, autologous perichondrium conchal cartilage graft may be effective in surgical management of Pseudomonal infectious scleritis when non-surgical medical treatment is ineffective. Further studies in larger, diverse populations are warranted to establish the effectiveness of the procedure.
		                        		
		                        		
		                        		
		                        			Anti-Bacterial Agents/therapeutic use
		                        			;
		                        		
		                        			Autografts
		                        			;
		                        		
		                        			Cartilage/surgery
		                        			;
		                        		
		                        			Communicable Diseases
		                        			;
		                        		
		                        			Debridement
		                        			;
		                        		
		                        			Eye Infections, Bacterial/etiology/*therapy
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Ophthalmologic Surgical Procedures
		                        			;
		                        		
		                        			Postoperative Complications
		                        			;
		                        		
		                        			Pseudomonas Infections/microbiology/*therapy
		                        			;
		                        		
		                        			Pseudomonas aeruginosa/*isolation & purification
		                        			;
		                        		
		                        			Pterygium/surgery
		                        			;
		                        		
		                        			Republic of Korea
		                        			;
		                        		
		                        			Sclera/*surgery/transplantation
		                        			;
		                        		
		                        			Scleritis/microbiology/*therapy
		                        			;
		                        		
		                        			Surgical Wound Infection/microbiology/*therapy
		                        			;
		                        		
		                        			Transplantation, Autologous
		                        			;
		                        		
		                        			Treatment Outcome
		                        			
		                        		
		                        	
6.Case Reports of Lacrimal Sac Tumors Discovered in Patients with Persistent Epiphora Following Dacryocystorhinostomy.
Ka Hyun LEE ; Sun Hyup HAN ; Jin Sook YOON
Korean Journal of Ophthalmology 2015;29(1):66-67
		                        		
		                        			
		                        			No abstract available.
		                        		
		                        		
		                        		
		                        			Aged
		                        			;
		                        		
		                        			Biopsy
		                        			;
		                        		
		                        			Carcinoma, Squamous Cell/diagnosis/*etiology
		                        			;
		                        		
		                        			Dacryocystorhinostomy/*adverse effects
		                        			;
		                        		
		                        			Eye Neoplasms/diagnosis/*etiology
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Lacrimal Apparatus/pathology/*surgery
		                        			;
		                        		
		                        			Lacrimal Apparatus Diseases/diagnosis/*etiology
		                        			;
		                        		
		                        			*Postoperative Complications
		                        			;
		                        		
		                        			Tomography, X-Ray Computed
		                        			
		                        		
		                        	
7.Orbital Dirofilariasis.
Se Hyun CHOI ; Namju KIM ; Jin Ho PAIK ; Jaeeun CHO ; Jong Yil CHAI
Korean Journal of Ophthalmology 2014;28(6):495-496
		                        		
		                        			
		                        			No abstract available.
		                        		
		                        		
		                        		
		                        			Aged
		                        			;
		                        		
		                        			Animals
		                        			;
		                        		
		                        			Diagnosis, Differential
		                        			;
		                        		
		                        			Dirofilaria immitis/*isolation & purification
		                        			;
		                        		
		                        			Dirofilariasis/*diagnosis/parasitology/surgery
		                        			;
		                        		
		                        			Eye Infections, Parasitic/*diagnosis/parasitology/surgery
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Ophthalmologic Surgical Procedures
		                        			;
		                        		
		                        			Orbital Diseases/*diagnosis/parasitology/surgery
		                        			
		                        		
		                        	
8.Primary orbital hydatid cyst: computed tomography and magnetic resonance imaging findings.
Pelin Seher ÖZTEKIN ; Behice Kaniye YILMAZ ; Fatma Dilek GOKHARMAN ; Pınar Nergis KOŞAR
Singapore medical journal 2014;55(11):e184-6
		                        		
		                        			
		                        			Orbital hydatid cyst is a rare form of hydatidosis, comprising less than 1% of all hydatid cysts reported. The first choice of treatment for orbital hydatid cyst is surgery. Preoperative diagnosis is important, so as to avoid rupture of the cyst and prevent the spread of the parasitic disease. Herein, we present the computed tomography and magnetic resonance imaging findings of a case of primary orbital hydatid cyst.
		                        		
		                        		
		                        		
		                        			Animals
		                        			;
		                        		
		                        			Echinococcosis
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			parasitology
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Echinococcus granulosus
		                        			;
		                        		
		                        			isolation & purification
		                        			;
		                        		
		                        			Eye Infections, Parasitic
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			parasitology
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Magnetic Resonance Imaging
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Multimodal Imaging
		                        			;
		                        		
		                        			Orbital Diseases
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			parasitology
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Tomography, X-Ray Computed
		                        			;
		                        		
		                        			methods
		                        			
		                        		
		                        	
9.Vitreomacular traction syndrome.
Lei SHAO ; Wenbin WEI ;
Chinese Medical Journal 2014;127(8):1566-1571
OBJECTIVEThis study aimed to review the available literature on vitreomacular traction (VMT) syndrome and propose the future study prospect in this field.
DATA SOURCESThe data used in this review were mainly obtained from articles listed in Medline and Pubmed (1970-2013). The search terms were "vitreomacular traction", "optical coherence tomography", "vitrectomy", and "ocriplasmin".
STUDY SELECTIONArticles regarding the pathophysiology, diagnosis, and treatments of VMT were selected and reviewed.
RESULTSVMT syndrome is a persistent attachment of vitreous to the macula in eyes with an incomplete posterior vitreous detachment and considered to be an uncommon status which correlated with some other macular disorders. Optical coherence tomography (OCT) can support a new way to examine and classify VMT. Nonoperative and operative intervenes on this disease have been developed recently, especially the intravitreal medical therapy.
CONCLUSIONSVMT syndrome may be associated with various disorders in the macular region, depending in part on the size and strength of the residual vitreomacular adhesion. Regular OCT monitoring is recommended to detect it. Patients with asymptomatic VMT should be observed for at least 2-3 months; nonoperative treatment with ocriplasmin should be considered when disorders persist; surgery is recommended if VMT-related disease is significant.
Eye Diseases ; diagnosis ; epidemiology ; surgery ; Humans ; Retinal Diseases ; diagnosis ; epidemiology ; surgery ; Risk Factors ; Tomography, Optical Coherence ; Vitreous Detachment ; diagnosis ; epidemiology ; surgery
10.Ocular complications following surgery of chronic suppurative otitis media.
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2014;29(8):726-732
		                        		
		                        			OBJECTIVE:
		                        			To investigate the rarely reported ocular complications following surgery of chronic suppurative otitis media (CSOM) and explore the possible mechanisms.
		                        		
		                        			METHOD:
		                        			The clinical data of 4,012 cases of CSOM treated with surgery were analyzed retrospectively, including age, sex, operation time, surgical approach, time of ocular symptoms presentation, duration of ocular symptoms, treatment and prognosis.
		                        		
		                        			RESULT:
		                        			Among the 4,012 cases, 109 patients (2.72%) developed ocular complication, of which 68.81% (75/109) suffered from blurred vision, 24.77% (27/109) presented only erythema on eyelids or mild periorbital edema, 4.59% (5/109) had erythema on eyelids with periorbital edema, and 1.83% (2/109) complained of periorbital ecchymosis and edema. All of these complications recovered themselves without any sequela.
		                        		
		                        			CONCLUSION
		                        			Ocular complications following surgery of CSOM are rarely reported. Pre-auricular incision and fascia harvesting, turbulence of venous and lymphatic drainage and preseptal cellulitis might be the risk factors. Blurred vision might be associated with eye injury during surgery and the use of anticholinergic agent.
		                        		
		                        		
		                        		
		                        			Chronic Disease
		                        			;
		                        		
		                        			Eye Diseases
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Otitis Media, Suppurative
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Postoperative Complications
		                        			;
		                        		
		                        			Retrospective Studies
		                        			;
		                        		
		                        			Risk Factors
		                        			
		                        		
		                        	
            
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