1.The Impact of Self-Compassion on Enhancing the Professional Quality of Life for Healthcare Workers
Journal of Korean Medical Science 2025;40(14):e141-
		                        		
		                        			
		                        			 Emphasizing the importance of psychological experiences in professional roles, this study explored the relationship between self-compassion and professional quality of life (ProQOL) among healthcare workers (HCWs). Sociodemographic characteristics, depressive symptoms, self-compassion, and ProQOL were assessed by conducting an online survey with 371 HCWs on coronavirus disease 2019 dedicated teams. Our findings indicate that self-compassion contributes to a better ProQOL, enhancing compassion satisfaction while reducing burnout and secondary traumatic stress, even when controlling depressive symptoms. These results have important implications fostering self-compassion interventions for a better ProQOL in HCWs. 
		                        		
		                        		
		                        		
		                        	
2.Effects of a thermoelectric element tourniquet on venipuncture pain and stress relief in Korea: a randomized controlled trial
Tae Jung LEE ; Jihoo HER ; Myung-Haeng HUR
Journal of Korean Biological Nursing Science 2025;27(2):179-190
		                        		
		                        			 Purpose:
		                        			This study developed a thermoelectric element (TEE) tourniquet integrating a tourniquet with a temperature control device capable of delivering heat or cold therapy. A randomized controlled trial was conducted to evaluate the effects of the TEE tourniquet on pain, stress, and satisfaction during venipuncture. 
		                        		
		                        			Methods:
		                        			In total, 118 hospitalized adults were randomly assigned to heat therapy (40~45°C), cold therapy (0~10°C), thermal grill illusion therapy (alternating heat and cold), or the control group. The TEE tourniquet was applied 10 cm above the puncture site. A temperature intervention began 5 seconds before cannulation and was maintained during the procedure, typically lasting 10 to 30 seconds. The control group received the TEE tourniquet without temperature activation. Outcomes included perceived pain and stress (numerical rating scale), observed pain (Wong-Baker FACES), SpO2, stress index, and participant satisfaction. 
		                        		
		                        			Results:
		                        			Significant differences were found among groups in perceived pain (F = 4.82, p = .003), observed pain (F = 5.50, p = .001), and perceived stress (F = 4.72, p = .004). The heat therapy group reported significantly lower pain and stress than the control group. No significant differences were found in SpO₂, the stress index, or satisfaction. 
		                        		
		                        			Conclusion
		                        			Heat therapy via the TEE tourniquet significantly reduced venipuncture-related pain and stress. Given its short application time and usability, this device may serve as a clinically useful nursing intervention to improve comfort during invasive procedures.  
		                        		
		                        		
		                        		
		                        	
3.Minocycline Susceptibility of Carbapenem-Resistant Acinetobacter baumannii Blood Isolates from a Single Center in Korea: Role of tetB in Resistance
Taeeun KIM ; Eun Hee JEON ; Yoon-Kyoung HONG ; Jiwon JUNG ; Min Jae KIM ; Heungsup SUNG ; Mi-Na KIM ; Sung-Han KIM ; Sang-Ho CHOI ; Sang-Oh LEE ; Yang Soo KIM ; Yong Pil CHONG
Infection and Chemotherapy 2025;57(1):111-118
		                        		
		                        			 Background:
		                        			Carbapenem-resistant Acinetobacter baumannii (CRAB) represents a devastating and growing global threat, calling for new antibiotic treatments. In Korea, the challenge of treating CRAB is compounded by high nosocomial acquisition rates and limited availability of novel antibiotics. Minocycline, a semisynthetic tetracycline derivative, has been proposed as a therapeutic option for CRAB infections. Nonsusceptibility to minocycline may occur through the efflux pump, TetB. The prevalence of tetB in A. baumannii has increased, along with higher minocycline minimum inhibitory concentrations (MICs). We aimed to evaluate minocycline susceptibility rates in clinical strains of CRAB, and the association between tetB carriage and minocycline susceptibility across different genotypes. 
		                        		
		                        			Materials and Methods:
		                        			Representative CRAB blood isolates were collected from Asan Medical Center, Seoul.Minocycline susceptibility was assessed using the Clinical and Laboratory Standards Institute (CLSI) breakpoint (≤4 mg/L) and the proposed pharmacokinetics (PK)/pharmacodynamics (PD) breakpoint (≤1 mg/L). Tigecycline was used as a comparator, and its susceptibility breakpoint for Enterobacterales defined by EUCAST was applied (≤0.5 mg/L).The presence of tetB was detected by PCR, and multilocus sequence typing (MLST) was performed using seven housekeeping genes. 
		                        		
		                        			Results:
		                        			Of the 160 CRAB blood isolates, 83.8% were susceptible to minocycline by the CLSI criteria, and 50.6% were PK-PD susceptible by the PK-PD criteria. The minocycline minimum inhibitory concentration (MIC)50 /MIC90 was 1/8 mg/L. tetB was present in 49% of isolates and was associated with a higher minocycline MIC (MIC50/90 2/8 mg/L vs. 1/2 mg/L). No clear correlation was observed between tetB positivity and tigecycline MIC. Nine MLSTs were identified, with significant differences in tetB carriage rates between the major sequence types. Notably, ST191, associated with non-tetB carriage and greater susceptibility to minocycline, declined over the study period (P=0.004), while ST451, associated with tetB carriage, increased. 
		                        		
		                        			Conclusion
		                        			tetB was present in 49% of CRAB isolates and was associated with higher MICs and non-susceptibility by both CLSI and PK-PD criteria. However, absence of tetB was not a reliable predictor of minocycline PK-PD susceptibility. Additionally, shifts over time towards genotypes with reduced minocycline susceptibility were observed. Further research is needed to correlate these findings with clinical outcomes and identify additional resistance mechanisms. 
		                        		
		                        		
		                        		
		                        	
4.Additional Screw Added to the Femoral Neck System Could Enhance the Stability of Pauwel Type III Femoral Neck Fractures:a Finite Element Analysis
Yonghan CHA ; Sunghoon PARK ; Chang-Ho JUNG ; Jin-Woo KIM ; Jun-Il YOO ; Jung-Taek KIM ; Yongho JEON ; Kyeong Jin HAN
Clinics in Orthopedic Surgery 2025;17(2):204-215
		                        		
		                        			 Background:
		                        			This study explores effective fixation methods for Pauwel type III femoral neck fractures by evaluating the biomechanical benefits of adding a screw to the Femoral Neck System (FNS). 
		                        		
		                        			Methods:
		                        			Computed tomography (CT) scans of an 82-year-old female patient with an intertrochanteric fracture were used to establish a finite element femur model with heterogeneous material properties. Finite element models of Pauwel type III fractures were created with and without an additional screw. The central and inferior trajectories of the FNS bolt were examined separately and combined with an additional screw for virtual fixation. Walking and stair-climbing loads were applied. 
		                        		
		                        			Results:
		                        			With the addition of a screw, both peak maximum and minimum principal strains consistently stayed comparable or decreased in models with both central and inferior bolt trajectories, while the volume of elements with principal strain exceeding 1% decreased by more than half. The peak von Mises stress observed in the implants ranged from 215.7 to 359.3 MPa, remaining below the titanium alloy's yield strength of 800 MPa. For normal walking, the addition of a screw to the central bolt trajectory model decreased the fracture gap by 50.6% and reduced sliding distance by 8.6%. For the inferior bolt trajectory, the gap was reduced by 57.9% and sliding distance by 25.0%.Under stair-climbing conditions, these improvements were also evident; the central trajectory model saw a halved fracture gap and a 7.9% decrease in sliding distance, while the inferior trajectory model experienced a 55.7% gap reduction and a 27.2% decrease in sliding distance. The additional screw increased the area ratio of the fracture site experiencing interfragmentary compression 34%–39%, while the additional screw alleviated peak interfragmentary compression by 12%–18% under both normal walking and stair-climbing conditions. 
		                        		
		                        			Conclusions
		                        			The addition of a screw reduced the fracture gap, sliding distance, and peak interfragmentary compression, while increasing the area ratio of interfragmentary compression under both walking and stair-climbing loads, regardless of the FNS bolt trajectory, suggesting a better mechanical environment for fracture healing. 
		                        		
		                        		
		                        		
		                        	
5.The Impact of Hospital Volume and Region on Mortality, Medical Costs, and Length of Hospital Stay in Elderly Patients Following Hip Fracture:A Nationwide Claims Database Analysis
Seung Hoon KIM ; Suk-Yong JANG ; Yonghan CHA ; Hajun JANG ; Bo-Yeon KIM ; Hyo-Jung LEE ; Gui-Ok KIM
Clinics in Orthopedic Surgery 2025;17(1):80-90
		                        		
		                        			 Background:
		                        			The purpose of our study was to analyze the effects of hospital volume and region on in-hospital and long-term mortality, direct medical costs (DMCs), and length of hospital stay (LOS) in elderly patients following hip fracture, utilizing nationwide claims data. 
		                        		
		                        			Methods:
		                        			This retrospective nationwide study sourced its subjects from the Korean National Health Insurance Review and Assessment Service database spanning from January 2011 to December 2018. A generalized estimating equation model with a Poisson distribution and logarithmic link function was used to estimate adjusted odds ratios (aORs) and 95% CIs to assess the association of hospital volume with in-hospital and 1-year mortality, DMCs, and LOS . 
		                        		
		                        			Results:
		                        			A total of 172,144 patients were included. Comparing the risk of in-hospital death between high-volume and low-volume hospitals, the risk of in-hospital death was 1.2 times higher at low-volume hospitals (aOR, 1.20; 95% CI, 1.07–1.33; p = 0.002).Additionally, the risk of death at 1 year was 1.05 times higher at low-volume hospitals (aOR, 1.05; 95% CI, 1.01–1.09; p = 0.008) compared to high-volume hospitals. DMCs were 0.84 times lower at low-volume hospitals for in-hospital period (aOR, 0.84; 95% CI, 0.84–0.85; p < 0.001) and 0.87 times lower for 1 year (aOR, 0.87; 95% CI, 0.86–0.88; p < 0.001) compared to high-volume hospitals. In-hospital LOS was 1.21 times longer at low-volume hospitals (aOR, 1.21; 95% CI, 1.20–1.22; p < 0.001) than at high-volume hospitals. In addition, the risk of in-hospital death was 1.22 times higher (aOR, 1.22; 95% CI, 1.12–1.33; p < 0.001) and the risk of 1-year death was 1.07 times higher (aOR, 1.07; 95% CI, 1.04–1.10; p < 0.001) at rural hospitals compared to urban hospitals. 
		                        		
		                        			Conclusions
		                        			Clinicians should focus on improving clinical outcomes for hip fracture patients in low-volume and rural hospital settings, with a specific emphasis on reducing mortality rates. 
		                        		
		                        		
		                        		
		                        	
6.Voice Profile Analysis of Post-COVID-19 Patients in South Korea: Gender and Diagnosis Duration
Jung Ho CHOI ; Ji Hye PARK ; Ah Ra JUNG
Journal of the Korean Society of Laryngology Phoniatrics and Logopedics 2025;36(1):19-25
		                        		
		                        			 Background and Objectives:
		                        			This study is the first to report on voice changes by gender and duration of infection in Korean post-COVID-19 patients. It analyzes the prevalence of voice-related symptoms, gender differences in acoustic parameters, and temporal recovery patterns of voice function.Materials and Method In this study, 85 patients with COVID-19 were recruited, voice-related symptoms were surveyed, and voice recordings of all participants were collected and analyzed by acoustic speech analysis. 
		                        		
		                        			Results:
		                        			The average age of 85 COVID-19 confirmed patients was 31 (range: 26.0–45.5) years old, and there were 35 males and 50 females. Voice analysis using the GRBAS scale and acoustic parameters was conducted among male and female patients. Results revealed varying distributions of GRBAS scores among males and females, with males exhibiting lower fundamental frequency (F0) but higher jitter and shimmer compared to females. When compared to normal adult voice values, female patients demonstrated a significant reduction in fundamental frequency, while male patients exhibited a significant increase in speaking fundamental frequency (SFF) alongside elevated jitter and shimmer. Additionally, analysis of voice parameters over time since COVID-19 diagnosis showed no significant differences among males, whereas females exhibited a significant increase in SFF after 90 days, approaching normal values. 
		                        		
		                        			Conclusion
		                        			This study emphasizes the significant impact of COVID-19 on voice production, with notable sex-specific differences and recovery patterns. These findings provide a foundation for developing targeted rehabilitation strategies to improve vocal outcomes in post-COVID-19 patients. 
		                        		
		                        		
		                        		
		                        	
7.Effects of a thermoelectric element tourniquet on venipuncture pain and stress relief in Korea: a randomized controlled trial
Tae Jung LEE ; Jihoo HER ; Myung-Haeng HUR
Journal of Korean Biological Nursing Science 2025;27(2):179-190
		                        		
		                        			 Purpose:
		                        			This study developed a thermoelectric element (TEE) tourniquet integrating a tourniquet with a temperature control device capable of delivering heat or cold therapy. A randomized controlled trial was conducted to evaluate the effects of the TEE tourniquet on pain, stress, and satisfaction during venipuncture. 
		                        		
		                        			Methods:
		                        			In total, 118 hospitalized adults were randomly assigned to heat therapy (40~45°C), cold therapy (0~10°C), thermal grill illusion therapy (alternating heat and cold), or the control group. The TEE tourniquet was applied 10 cm above the puncture site. A temperature intervention began 5 seconds before cannulation and was maintained during the procedure, typically lasting 10 to 30 seconds. The control group received the TEE tourniquet without temperature activation. Outcomes included perceived pain and stress (numerical rating scale), observed pain (Wong-Baker FACES), SpO2, stress index, and participant satisfaction. 
		                        		
		                        			Results:
		                        			Significant differences were found among groups in perceived pain (F = 4.82, p = .003), observed pain (F = 5.50, p = .001), and perceived stress (F = 4.72, p = .004). The heat therapy group reported significantly lower pain and stress than the control group. No significant differences were found in SpO₂, the stress index, or satisfaction. 
		                        		
		                        			Conclusion
		                        			Heat therapy via the TEE tourniquet significantly reduced venipuncture-related pain and stress. Given its short application time and usability, this device may serve as a clinically useful nursing intervention to improve comfort during invasive procedures.  
		                        		
		                        		
		                        		
		                        	
8.The Impact of Self-Compassion on Enhancing the Professional Quality of Life for Healthcare Workers
Journal of Korean Medical Science 2025;40(14):e141-
		                        		
		                        			
		                        			 Emphasizing the importance of psychological experiences in professional roles, this study explored the relationship between self-compassion and professional quality of life (ProQOL) among healthcare workers (HCWs). Sociodemographic characteristics, depressive symptoms, self-compassion, and ProQOL were assessed by conducting an online survey with 371 HCWs on coronavirus disease 2019 dedicated teams. Our findings indicate that self-compassion contributes to a better ProQOL, enhancing compassion satisfaction while reducing burnout and secondary traumatic stress, even when controlling depressive symptoms. These results have important implications fostering self-compassion interventions for a better ProQOL in HCWs. 
		                        		
		                        		
		                        		
		                        	
9.Additional Screw Added to the Femoral Neck System Could Enhance the Stability of Pauwel Type III Femoral Neck Fractures:a Finite Element Analysis
Yonghan CHA ; Sunghoon PARK ; Chang-Ho JUNG ; Jin-Woo KIM ; Jun-Il YOO ; Jung-Taek KIM ; Yongho JEON ; Kyeong Jin HAN
Clinics in Orthopedic Surgery 2025;17(2):204-215
		                        		
		                        			 Background:
		                        			This study explores effective fixation methods for Pauwel type III femoral neck fractures by evaluating the biomechanical benefits of adding a screw to the Femoral Neck System (FNS). 
		                        		
		                        			Methods:
		                        			Computed tomography (CT) scans of an 82-year-old female patient with an intertrochanteric fracture were used to establish a finite element femur model with heterogeneous material properties. Finite element models of Pauwel type III fractures were created with and without an additional screw. The central and inferior trajectories of the FNS bolt were examined separately and combined with an additional screw for virtual fixation. Walking and stair-climbing loads were applied. 
		                        		
		                        			Results:
		                        			With the addition of a screw, both peak maximum and minimum principal strains consistently stayed comparable or decreased in models with both central and inferior bolt trajectories, while the volume of elements with principal strain exceeding 1% decreased by more than half. The peak von Mises stress observed in the implants ranged from 215.7 to 359.3 MPa, remaining below the titanium alloy's yield strength of 800 MPa. For normal walking, the addition of a screw to the central bolt trajectory model decreased the fracture gap by 50.6% and reduced sliding distance by 8.6%. For the inferior bolt trajectory, the gap was reduced by 57.9% and sliding distance by 25.0%.Under stair-climbing conditions, these improvements were also evident; the central trajectory model saw a halved fracture gap and a 7.9% decrease in sliding distance, while the inferior trajectory model experienced a 55.7% gap reduction and a 27.2% decrease in sliding distance. The additional screw increased the area ratio of the fracture site experiencing interfragmentary compression 34%–39%, while the additional screw alleviated peak interfragmentary compression by 12%–18% under both normal walking and stair-climbing conditions. 
		                        		
		                        			Conclusions
		                        			The addition of a screw reduced the fracture gap, sliding distance, and peak interfragmentary compression, while increasing the area ratio of interfragmentary compression under both walking and stair-climbing loads, regardless of the FNS bolt trajectory, suggesting a better mechanical environment for fracture healing. 
		                        		
		                        		
		                        		
		                        	
10.The Impact of Hospital Volume and Region on Mortality, Medical Costs, and Length of Hospital Stay in Elderly Patients Following Hip Fracture:A Nationwide Claims Database Analysis
Seung Hoon KIM ; Suk-Yong JANG ; Yonghan CHA ; Hajun JANG ; Bo-Yeon KIM ; Hyo-Jung LEE ; Gui-Ok KIM
Clinics in Orthopedic Surgery 2025;17(1):80-90
		                        		
		                        			 Background:
		                        			The purpose of our study was to analyze the effects of hospital volume and region on in-hospital and long-term mortality, direct medical costs (DMCs), and length of hospital stay (LOS) in elderly patients following hip fracture, utilizing nationwide claims data. 
		                        		
		                        			Methods:
		                        			This retrospective nationwide study sourced its subjects from the Korean National Health Insurance Review and Assessment Service database spanning from January 2011 to December 2018. A generalized estimating equation model with a Poisson distribution and logarithmic link function was used to estimate adjusted odds ratios (aORs) and 95% CIs to assess the association of hospital volume with in-hospital and 1-year mortality, DMCs, and LOS . 
		                        		
		                        			Results:
		                        			A total of 172,144 patients were included. Comparing the risk of in-hospital death between high-volume and low-volume hospitals, the risk of in-hospital death was 1.2 times higher at low-volume hospitals (aOR, 1.20; 95% CI, 1.07–1.33; p = 0.002).Additionally, the risk of death at 1 year was 1.05 times higher at low-volume hospitals (aOR, 1.05; 95% CI, 1.01–1.09; p = 0.008) compared to high-volume hospitals. DMCs were 0.84 times lower at low-volume hospitals for in-hospital period (aOR, 0.84; 95% CI, 0.84–0.85; p < 0.001) and 0.87 times lower for 1 year (aOR, 0.87; 95% CI, 0.86–0.88; p < 0.001) compared to high-volume hospitals. In-hospital LOS was 1.21 times longer at low-volume hospitals (aOR, 1.21; 95% CI, 1.20–1.22; p < 0.001) than at high-volume hospitals. In addition, the risk of in-hospital death was 1.22 times higher (aOR, 1.22; 95% CI, 1.12–1.33; p < 0.001) and the risk of 1-year death was 1.07 times higher (aOR, 1.07; 95% CI, 1.04–1.10; p < 0.001) at rural hospitals compared to urban hospitals. 
		                        		
		                        			Conclusions
		                        			Clinicians should focus on improving clinical outcomes for hip fracture patients in low-volume and rural hospital settings, with a specific emphasis on reducing mortality rates. 
		                        		
		                        		
		                        		
		                        	
            
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