1.Effect of ultraviolet photofunctionalization of dental titanium implants on osseointegration.
Christian MEHL ; Matthias KERN ; Friederike NEUMANN ; Telse BÄHR ; Jörg WILTFANG ; Volker GASSLING
Journal of Zhejiang University. Science. B 2018;19(7):525-534
		                        		
		                        			OBJECTIVE:
		                        			The aim of the current study was to evaluate the effect of ultraviolet (UV) photofunctionalization of dental titanium implants with exposure to the oral cavity on osseointegration in an animal model.
		                        		
		                        			METHODS:
		                        			Forty-eight titanium implants (Camlog Conelog 4.3 mmx9.0 mm) were placed epicrestally into the edentulous jaws of three minipigs and implant stability was assessed by measuring the implant stability quotient (ISQ). Prior to implantation half of the implants were photofunctionalized with intense UV-light. After three months, the implants were exposed and ISQ was measured again. After six months of implant exposure, the minipigs were sacrificed and the harvested specimens were analyzed using histomorphometric, light, and fluorescence microscopy.
		                        		
		                        			MAIN RESULTS:
		                        			Forty-two of 48 implants osseointegrated. The overall mean bone-implant contact area (BIC) was (64±22)%. No significant differences were found in BIC or ISQ value (multivariate analysis of variance (MANOVA), P>0.05) between implants with and without exposure to UV photofunctionalization.
		                        		
		                        			CONCLUSIONS
		                        			No significant effects were observed on osseointegration of dental titanium implants nine months after exposure of UV photofunctionalization.
		                        		
		                        		
		                        		
		                        			Animals
		                        			;
		                        		
		                        			Dental Implantation, Endosseous
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Dental Implants
		                        			;
		                        		
		                        			Equipment Failure Analysis
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Hydrophobic and Hydrophilic Interactions
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Models, Animal
		                        			;
		                        		
		                        			Osseointegration
		                        			;
		                        		
		                        			Surface Properties
		                        			;
		                        		
		                        			Swine
		                        			;
		                        		
		                        			Swine, Miniature
		                        			;
		                        		
		                        			Titanium
		                        			;
		                        		
		                        			Ultraviolet Rays
		                        			
		                        		
		                        	
2.Fracture and migration of implantable venous access port catheters: Cause analysis and management of 4 cases.
Shu-ping XIAO ; Bin XIONG ; Jun CHU ; Xiao-fang LI ; Qi YAO ; Chuan-sheng ZHENG
Journal of Huazhong University of Science and Technology (Medical Sciences) 2015;35(5):763-765
		                        		
		                        			
		                        			This study aimed to investigate the causes and managements of the fractures and migrations of the implantable venous access port catheter (IVAPC). The fracture or migration of IVAPC occurred in 4 patients who were treated between May 2012 and January 2014 in Union Hospital, Wuhan, China. The port catheter leakage was found in 2 cases during drug infusion. Catheters that dislodged to the superior vena cava and right atrium were confirmed by port angiogram. The two dislodged catheters were successfully retrieved by interventional procedures. Catheter fracture occurred in two cases during port removal. One catheter was eventually removed from the subclavian vein through right clavicle osteotomy and subclavian venotomy, and the other removed by external jugular venotomy. Flushing the port in high pressure and injury of the totally implantable venous access port (TIVP) during implantation are usually responsible for catheter displacement. Interventional retrieval procedure can be used if the catheter dislodges to the vena cava and right atrium. Catheter fracture may occur during removal if clipping syndrome occurs or the catheter is sutured very tight during implantation.
		                        		
		                        		
		                        		
		                        			Angiography
		                        			;
		                        		
		                        			Catheters, Indwelling
		                        			;
		                        		
		                        			Central Venous Catheters
		                        			;
		                        		
		                        			Child
		                        			;
		                        		
		                        			Child, Preschool
		                        			;
		                        		
		                        			Device Removal
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Equipment Failure
		                        			;
		                        		
		                        			Equipment Failure Analysis
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Heart Atria
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Osteotomy
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Suture Techniques
		                        			;
		                        		
		                        			Vena Cava, Superior
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Young Adult
		                        			
		                        		
		                        	
3.Surgeon Custom-Made Iliac Branch Device to Salvage Hypogastric Artery during Endovascular Aneurysm Repair.
Young Eun PARK ; Jae Hoon LEE ; Woo Sung YUN ; Ki Hyuk PARK
Journal of Korean Medical Science 2014;29(12):1678-1683
		                        		
		                        			
		                        			Endovascular salvage of the hypogastric artery using iliac branch device (IBD) during endovascular aortic aneurysm repair (EVAR), offers less invasive alternative solution to surgery to prevent pelvic ischemia. We have performed the first Korean surgeon custom-made IBD for this purpose to overcome the limitation of unavailability of the devices in Korea. Four patients with abdominal aortic aneurysm with bilateral common iliac artery aneurysm (CIAA) were treated using custom-made IBDs from October 2013 to December 2013. IBD was created in back table before EVAR operation using TFLE Zenith iliac limb stent graft (Cook Inc.). Three V12 (Atrium, Inc.) one Viabahn (Gore, Inc.) were used for bridging between IBD and target hypogastric artery. With this modification of IBD procedure, exteriorize the guide wire without snare device is possible which offers another benefit in terms of reducing medical costs comparing to commercial IBD. All operations were successful without any device related complications or postoperative endoleaks. During the mean follow up of 3 months, all IBD were patent without clinical complications. Surgeon custom made IBD is feasible and useful to preserve pelvic perfusion especially in the situation of limited commercial IBD availability in many countries. Long-term follow-up is needed to evaluate stent graft patency and IBD-related complications.
		                        		
		                        		
		                        		
		                        			Aged
		                        			;
		                        		
		                        			Aortic Aneurysm, Abdominal/*surgery
		                        			;
		                        		
		                        			*Blood Vessel Prosthesis
		                        			;
		                        		
		                        			Endovascular Procedures/*instrumentation
		                        			;
		                        		
		                        			Equipment Design
		                        			;
		                        		
		                        			Equipment Failure Analysis
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Iliac Aneurysm/*surgery
		                        			;
		                        		
		                        			Iliac Artery/*surgery
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Salvage Therapy/*instrumentation/methods
		                        			;
		                        		
		                        			*Stents
		                        			
		                        		
		                        	
4.Disconnection of the Rubber Tip of Arrow-Trerotola Percutaneous Thrombolytic Device.
Han Myun KIM ; Hyo Cheol KIM ; Sungmin WOO ; Kyu Ri SON ; Hwan Jun JAE
Korean Journal of Radiology 2014;15(2):254-257
		                        		
		                        			
		                        			A rubber tip disconnection of Arrow-Trerotola percutaneous thrombolytic device (PTD) may occur occasionally. We experienced 5 cases of a rubber tip disconnection among 453 mechanical thrombectomy sessions with the use of PTD. We present a report about these five cases and suggest possible causes for the occurrences.
		                        		
		                        		
		                        		
		                        			Aged
		                        			;
		                        		
		                        			Catheter Obstruction/*etiology
		                        			;
		                        		
		                        			Equipment Failure Analysis/*methods
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Renal Dialysis/*instrumentation
		                        			;
		                        		
		                        			Rubber
		                        			;
		                        		
		                        			Thrombectomy/*instrumentation
		                        			;
		                        		
		                        			Treatment Outcome
		                        			
		                        		
		                        	
5.Computer-aided design and custom-made guide in corrective osteotomy for complex femoral deformity.
Wei CHAI ; Meng XU ; Guo-qiang ZHANG ; Li-hai ZHANG ; Wen-long GOU ; Ming NI ; Ji-ying CHEN
Journal of Huazhong University of Science and Technology (Medical Sciences) 2013;33(3):398-405
		                        		
		                        			
		                        			Preoperative planning of corrective osteotomy with traditional radiography has limitations in regards to determining the ideal osteotomy location and orientation in three-dimensional femoral deformities. Though a successful operation can be planned preoperatively, intraoperative contingencies might adhere to the procedural plan in the performance of operation. To efficiently perform a planned procedure, proposed is a design to implement three-dimensional reconstruction photography, based on computer-tomography (CT) scan. A custom-made guide was designed to navigate the osteotomy as planned, and additionally, a personalized intramedullary nail was used for fixation after osteotomy. Three-dimensional (3D) photography of deformed femur was established based on the CT dataset and transferred into 3D photography processing software for further planning. Osteotomy planes were designed and adjusted at deformity sites to correct the 3D deformities. The methodology of a custom-made osteotomy guide was introduced in femoral corrective osteotomy, for the first time, to navigate the operation as planned. After the virtual osteotomy and reduction of bone segments, the parameters of a custom-made intramedullary nail were measured for manufacturing. Findings Virtual operation in computer shows complete correction of the 3D deformity. The osteotomy guide, obtained by rapid-prototyping techniques, navigates mimicking surgery on rapid-prototyping model of the involved femur as planned. Internal fixation was achieved using the custom-made intramedullary nail. Interpretation three-dimensional visualization introduces an advantage in preoperative planning for corrective osteotomy of 3D femoral deformity, and the custom-made osteotomy guide is crucial to realize such a deliberate plan during the actual procedures. The internal fixator, such as an intramedullary nail, can be modified or personalized for fixation in unique cases.
		                        		
		                        		
		                        		
		                        			Computer-Aided Design
		                        			;
		                        		
		                        			Equipment Failure Analysis
		                        			;
		                        		
		                        			Femur
		                        			;
		                        		
		                        			abnormalities
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Fiducial Markers
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Imaging, Three-Dimensional
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Osteotomy
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Reconstructive Surgical Procedures
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Surgery, Computer-Assisted
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Tomography, X-Ray Computed
		                        			;
		                        		
		                        			methods
		                        			
		                        		
		                        	
6.Quantitative comparison of calcium hydroxide removal by EndoActivator, ultrasonic and ProTaper file agitation techniques: an in vitro study.
Huda Yasir KHALEEL ; Ahmed Jawad AL-ASHAW ; Yan YANG ; Ai-hui PANG ; Jing-zhi MA
Journal of Huazhong University of Science and Technology (Medical Sciences) 2013;33(1):142-145
		                        		
		                        			
		                        			Calcium hydroxide (CH) dressing residues can compromise endodontic sealing. This study aimed to evaluate the amount of remaining CH in root canals after mechanical removal by four groups of irrigation techniques including needle irrigation only, ProTaper file, EndoActivator, and ultrasonic file. Fifteen extracted single-rooted teeth were collected and used for all four groups. The samples were firstly prepared by ProTaper rotary instruments, and then sectioned longitudinally through the long axis of the root canals, followed by final reassembling by wires. CH was kept in the canals for 7 days setting. The removal procedure began with 5 mL of 2.5% sodium hypochlorite (NaOCl) followed by 1 mL of 17% ethylenediaminetetraacetic acid and a final irrigation with 5 mL of 2.5% NaOCl solution for all groups. No additional agitation of the irrigant was performed in group 1, while agitation for 20 s between irrigants was done with F2 ProTaper rotary file in group 2, EndoActivator with tip size 25/.04 in group 3 and by an ultrasonic file 25/.02 in group 4. The total activation time was 60 s. The roots were then disassembled and captured by digital camera. The ratio of CH coated surface area to the surface area of the whole canal as well as each third of the canal was calculated. The data were statistically analyzed by one-way ANOVA using post hoc Tukey test. Results showed that none of the four techniques could remove all CH. No significant difference was found between EndoActivator and ultrasonic techniques. However, they both removed significantly more CH than ProTaper and needle irrigation (P=0.0001). In conclusion, the sonic and ultrasonic agitation techniques were more effective in removing intracanal medicaments than the ProTaper rotary file and needle irrigation in all thirds of the canal.
		                        		
		                        		
		                        		
		                        			Calcium Hydroxide
		                        			;
		                        		
		                        			isolation & purification
		                        			;
		                        		
		                        			Dental Instruments
		                        			;
		                        		
		                        			Dental Pulp Cavity
		                        			;
		                        		
		                        			chemistry
		                        			;
		                        		
		                        			Equipment Design
		                        			;
		                        		
		                        			Equipment Failure Analysis
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			In Vitro Techniques
		                        			;
		                        		
		                        			Root Canal Irrigants
		                        			;
		                        		
		                        			isolation & purification
		                        			;
		                        		
		                        			Root Canal Preparation
		                        			;
		                        		
		                        			instrumentation
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Sonication
		                        			;
		                        		
		                        			instrumentation
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Therapeutic Irrigation
		                        			;
		                        		
		                        			instrumentation
		                        			
		                        		
		                        	
7.Multiple coatings can improve the bond durability of one-step self-etching adhesive to primary dentin.
Lin MA ; Jian-feng ZHOU ; Quan JING ; Ji-zhi ZHAO ; Kuo WAN
Chinese Medical Sciences Journal 2012;27(2):106-111
OBJECTIVETo investigate whether multiple coatings can improve the bond durability of one-step self-etching adhesive to primary dentin.
METHODSTwelve caries-free human primary molars were randomly divided into 2 groups. In group 1, each tooth was hemisected into 2 halves. One half was assigned to the control subgroup 1, which was bonded with a commercially available one-step self-etching adhesive according to the manufacturer's instructions; the other half was assigned to experimental subgroup 1, in which the adhesive was applied three times before light curing. In group 2, one split half tooth was bonded with a commercially available one-step self-etching adhesive according to the manufacturer's instructions; for the other half, three layers of adhesive were applied with each successive layer of light curing. Specimens were stored in 0.9% NaCl containing 0.02% sodium azide at 37℃ for 18 months and then were subjected to microtensile bond strength test and the fracture mode analysis.
RESULTSWhen the adhesive was applied three times before light curing, the bond strength of the experimental subgroup 1 was significantly higher than that of the control subgroup 1 (47.46∓13.91 vs. 38.12∓11.21 MPa, P<0.05). When using the technique of applying multiple layers of adhesive with each successive layer of light curing, no difference was observed in bond strength between the control subgroup and the experimental subgroup (39.40±8.87 vs. 40.87±9.33 MPa, P>0.05).
CONCLUSIONMultiple coatings can improve the bond durability of one-step self-etching adhesive to primary dentin when using the technique of light-curing after applying 3 layers of adhesive.
Acid Etching, Dental ; methods ; Adhesiveness ; Child ; Coated Materials, Biocompatible ; chemical synthesis ; chemistry ; pharmacology ; Dental Cements ; chemical synthesis ; chemistry ; pharmacology ; Dental Prosthesis ; Dental Restoration Failure ; Dentin ; chemistry ; drug effects ; Dentin-Bonding Agents ; pharmacology ; Electroplating ; methods ; Equipment Failure Analysis ; Humans ; Materials Testing ; Tensile Strength ; drug effects
8.Three-dimensional finite element analysis of bone stress distribution around the hip joint prosthesis with stepped stem.
Ruichang TAN ; Hongsong FAN ; Fang WU ; Jiyong CHEN ; Jiaoming LUO ; Xindong ZHANG
Journal of Biomedical Engineering 2011;28(4):732-736
		                        		
		                        			
		                        			Based on the CT data, a medical treatment FE model of hip joint prosthesis with stepped stem was rebuilt according the anatomy of the hip joint. Under the loads of 1.5 times standard body weight (70kg), the mechanical behavior of the treatment model was calculated, and the influence of step structure and distribution for stepped stem on femur stress and stability of total hip replacement were analyzed by three-dimensional finite element analysis (3D-FEA). The results show that the step structure changs the bone stress transmission on the interface of stepped stem and femur, and benefits to reduce stress-shielding in the femur. For the same distribution of step, the reduction of stress-shielding for raised stepped stem is better than that for concave stepped stem. The raised stepped stem of which the steps is distributed one of third part of the stem is of the best effect of reduction of stress shielding in all of the analysis models, and is a beneficial mechanical design to relieves osteoporosis or osteopenia of femur caused by stress-shielding and improve the reliability of it in clinic.
		                        		
		                        		
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Arthroplasty, Replacement, Hip
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Biomechanical Phenomena
		                        			;
		                        		
		                        			Computer Simulation
		                        			;
		                        		
		                        			Equipment Failure Analysis
		                        			;
		                        		
		                        			Finite Element Analysis
		                        			;
		                        		
		                        			Hip Prosthesis
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Imaging, Three-Dimensional
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Models, Biological
		                        			;
		                        		
		                        			Prosthesis Design
		                        			;
		                        		
		                        			Stress, Mechanical
		                        			;
		                        		
		                        			Tomography, Spiral Computed
		                        			;
		                        		
		                        			Weight-Bearing
		                        			;
		                        		
		                        			physiology
		                        			
		                        		
		                        	
9.Case study of detecting and maintenance of AB 7300PCR.
Wei WANG ; Hongbiao YANG ; Jixiang LIU
Chinese Journal of Medical Instrumentation 2010;34(3):232-233
		                        		
		                        			
		                        			The AB 7300 Real-time PCR Systems in our hospital have been detected malfunction for three times in a short term. The detection indicated the major reason for the malfunction attributed to the fuse of the solder of the COVER at the same position with the serial number 4344490 D1. This article explicitly introduces how to detect and maintain this equipment. It serves as a good reference for colleagues. Meanwhile the author raises five issues for further exploration and discussion.
		                        		
		                        		
		                        		
		                        			Equipment Failure Analysis
		                        			;
		                        		
		                        			Maintenance
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Polymerase Chain Reaction
		                        			;
		                        		
		                        			instrumentation
		                        			;
		                        		
		                        			methods
		                        			
		                        		
		                        	
10.Review of the design of artificial knee joint simulation test.
Feng LI ; Yuanchao LI ; Chengtao WANG
Journal of Biomedical Engineering 2010;27(2):448-452
		                        		
		                        			
		                        			Artificial knee joint simulation test is an important form in the research and evaluation of prosthetic material and design. Natural knee joint could not be tested by conventional instruments because of complex motion and load in movement. Simulation test designed for artificial knee is needed. At present, two kinds of simulation, namely simplification method and complete simulation, are widely used. Complete simulation can be used for simultaneous evaluation of material and design of prosthesis, whereas simplification method is only useful in evaluating the material of prosthesis. In international standards, there are already two protocols for artificial knee joint experiment, namely load control and displacement control. This paper also reviews the evaluation criteria and measurement standards for artificial knee joint simulation test, and then envisages the researches in future.
		                        		
		                        		
		                        		
		                        			Arthroplasty, Replacement, Knee
		                        			;
		                        		
		                        			instrumentation
		                        			;
		                        		
		                        			Computer Simulation
		                        			;
		                        		
		                        			Computer-Aided Design
		                        			;
		                        		
		                        			Equipment Failure Analysis
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Knee Prosthesis
		                        			;
		                        		
		                        			Prosthesis Design
		                        			;
		                        		
		                        			methods
		                        			
		                        		
		                        	
            
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