Purpose: This study aimed to examine current global practices in regenerative therapy (RT) for erectile dysfunction (ED) and to establish expert recommendations for its use, addressing the current lack of solid evidence and standardized guidelines. Materials and Methods: A 39-question survey was developed by senior Global Andrology Forum (GAF) experts to comprehensively cover clinical aspects of RT. This was distributed globally via a secure online Google Form to ED specialists through the GAF website, international professional societies, and social media, the responses were analyzed and presented for frequencies as percentages. Consensus on expert recommendations for RT use was achieved using the Delphi method. Results: Out of 479 respondents from 62 countries, a third reported using RT for ED. The most popular treatment was low-intensity shock wave therapy (54.6%), followed by platelet-rich plasma (24.5%) and their combination (14.7%), with stem cell therapy being the least used (3.7%). The primary indication for RT was the refractory or adverse effects of PDE5 inhibitors, with the best effectiveness reported in middle-aged and mild-to-moderate ED patients. Respondents were confident about its overall safety, with a significant number expressing interest in RT’s future use, despite pending guidelines support. Conclusions This inaugural global survey reveals a growing use of RT in ED treatment, showcasing its diverse clinical applications and potential for future widespread adoption. However, the lack of comprehensive evidence and clear guidelines requires further research to standardize RT practices in ED treatment.

Purpose: This study aimed to examine current global practices in regenerative therapy (RT) for erectile dysfunction (ED) and to establish expert recommendations for its use, addressing the current lack of solid evidence and standardized guidelines. Materials and Methods: A 39-question survey was developed by senior Global Andrology Forum (GAF) experts to comprehensively cover clinical aspects of RT. This was distributed globally via a secure online Google Form to ED specialists through the GAF website, international professional societies, and social media, the responses were analyzed and presented for frequencies as percentages. Consensus on expert recommendations for RT use was achieved using the Delphi method. Results: Out of 479 respondents from 62 countries, a third reported using RT for ED. The most popular treatment was low-intensity shock wave therapy (54.6%), followed by platelet-rich plasma (24.5%) and their combination (14.7%), with stem cell therapy being the least used (3.7%). The primary indication for RT was the refractory or adverse effects of PDE5 inhibitors, with the best effectiveness reported in middle-aged and mild-to-moderate ED patients. Respondents were confident about its overall safety, with a significant number expressing interest in RT’s future use, despite pending guidelines support. Conclusions This inaugural global survey reveals a growing use of RT in ED treatment, showcasing its diverse clinical applications and potential for future widespread adoption. However, the lack of comprehensive evidence and clear guidelines requires further research to standardize RT practices in ED treatment.

Purpose: This study aimed to examine current global practices in regenerative therapy (RT) for erectile dysfunction (ED) and to establish expert recommendations for its use, addressing the current lack of solid evidence and standardized guidelines. Materials and Methods: A 39-question survey was developed by senior Global Andrology Forum (GAF) experts to comprehensively cover clinical aspects of RT. This was distributed globally via a secure online Google Form to ED specialists through the GAF website, international professional societies, and social media, the responses were analyzed and presented for frequencies as percentages. Consensus on expert recommendations for RT use was achieved using the Delphi method. Results: Out of 479 respondents from 62 countries, a third reported using RT for ED. The most popular treatment was low-intensity shock wave therapy (54.6%), followed by platelet-rich plasma (24.5%) and their combination (14.7%), with stem cell therapy being the least used (3.7%). The primary indication for RT was the refractory or adverse effects of PDE5 inhibitors, with the best effectiveness reported in middle-aged and mild-to-moderate ED patients. Respondents were confident about its overall safety, with a significant number expressing interest in RT’s future use, despite pending guidelines support. Conclusions This inaugural global survey reveals a growing use of RT in ED treatment, showcasing its diverse clinical applications and potential for future widespread adoption. However, the lack of comprehensive evidence and clear guidelines requires further research to standardize RT practices in ED treatment.

Purpose: This study aimed to examine current global practices in regenerative therapy (RT) for erectile dysfunction (ED) and to establish expert recommendations for its use, addressing the current lack of solid evidence and standardized guidelines. Materials and Methods: A 39-question survey was developed by senior Global Andrology Forum (GAF) experts to comprehensively cover clinical aspects of RT. This was distributed globally via a secure online Google Form to ED specialists through the GAF website, international professional societies, and social media, the responses were analyzed and presented for frequencies as percentages. Consensus on expert recommendations for RT use was achieved using the Delphi method. Results: Out of 479 respondents from 62 countries, a third reported using RT for ED. The most popular treatment was low-intensity shock wave therapy (54.6%), followed by platelet-rich plasma (24.5%) and their combination (14.7%), with stem cell therapy being the least used (3.7%). The primary indication for RT was the refractory or adverse effects of PDE5 inhibitors, with the best effectiveness reported in middle-aged and mild-to-moderate ED patients. Respondents were confident about its overall safety, with a significant number expressing interest in RT’s future use, despite pending guidelines support. Conclusions This inaugural global survey reveals a growing use of RT in ED treatment, showcasing its diverse clinical applications and potential for future widespread adoption. However, the lack of comprehensive evidence and clear guidelines requires further research to standardize RT practices in ED treatment.

Purpose: This study aimed to examine current global practices in regenerative therapy (RT) for erectile dysfunction (ED) and to establish expert recommendations for its use, addressing the current lack of solid evidence and standardized guidelines. Materials and Methods: A 39-question survey was developed by senior Global Andrology Forum (GAF) experts to comprehensively cover clinical aspects of RT. This was distributed globally via a secure online Google Form to ED specialists through the GAF website, international professional societies, and social media, the responses were analyzed and presented for frequencies as percentages. Consensus on expert recommendations for RT use was achieved using the Delphi method. Results: Out of 479 respondents from 62 countries, a third reported using RT for ED. The most popular treatment was low-intensity shock wave therapy (54.6%), followed by platelet-rich plasma (24.5%) and their combination (14.7%), with stem cell therapy being the least used (3.7%). The primary indication for RT was the refractory or adverse effects of PDE5 inhibitors, with the best effectiveness reported in middle-aged and mild-to-moderate ED patients. Respondents were confident about its overall safety, with a significant number expressing interest in RT’s future use, despite pending guidelines support. Conclusions This inaugural global survey reveals a growing use of RT in ED treatment, showcasing its diverse clinical applications and potential for future widespread adoption. However, the lack of comprehensive evidence and clear guidelines requires further research to standardize RT practices in ED treatment.

Vertebral artery dissection (VAD) is a rare but serious safety concern associated with spinal manipulative therapy. This report highlights the occurrence of such condition in a 35-year-old male without predisposing risk factors. The patient has had dizziness and occipital pain of new onset following chirotherapy for the neck spines. On admission, magnetic resonance angiography depicted a dissecting dilatation at the intracranial portion of the right vertebral artery. He was placed on antithrombotic therapy and fluid supplementation. His presenting symptoms completely remitted without recurrence. Follow-up images 4 months later showed resolution of the arterial dissection without progression to rupture. The study with featured images facilitates the physicians better understand VAD in those with neurologic complaints following chiropractic manipulation of the cervical vertebra.

Chiropractic care, known for its non-invasive and hands-on approach to healthcare, can occasionally lead to adverse reactions. This case report details an unusual occurrence of intracranial hypotension (IH) in a 30-year-old female who received chiropractic care for neck pain. The patient experienced a throbbing positional headache five days after mobilization and adjustment of the cervical spine. Upon admission, lumbar puncture performed in the lateral position revealed an opening pressure of 55 mm H2O. Magnetic resonance imaging showed subdural fluid collection and diffuse pachymeningeal enhancement in the cerebral hemispheres. Radioisotope cisternography revealed dural leakage at the upper cervical level. Following unsuccessful supportive measures, the patient underwent treatment with an epidural blood patch. After the treatment, her postural headaches completely subsided without recurrence. This report underscores that IH syndrome is a rare yet clinically significant complication that may be associated with manipulation of the upper spine.

Vertebral artery dissection (VAD) is a rare but serious safety concern associated with spinal manipulative therapy. This report highlights the occurrence of such condition in a 35-year-old male without predisposing risk factors. The patient has had dizziness and occipital pain of new onset following chirotherapy for the neck spines. On admission, magnetic resonance angiography depicted a dissecting dilatation at the intracranial portion of the right vertebral artery. He was placed on antithrombotic therapy and fluid supplementation. His presenting symptoms completely remitted without recurrence. Follow-up images 4 months later showed resolution of the arterial dissection without progression to rupture. The study with featured images facilitates the physicians better understand VAD in those with neurologic complaints following chiropractic manipulation of the cervical vertebra.

Chiropractic care, known for its non-invasive and hands-on approach to healthcare, can occasionally lead to adverse reactions. This case report details an unusual occurrence of intracranial hypotension (IH) in a 30-year-old female who received chiropractic care for neck pain. The patient experienced a throbbing positional headache five days after mobilization and adjustment of the cervical spine. Upon admission, lumbar puncture performed in the lateral position revealed an opening pressure of 55 mm H2O. Magnetic resonance imaging showed subdural fluid collection and diffuse pachymeningeal enhancement in the cerebral hemispheres. Radioisotope cisternography revealed dural leakage at the upper cervical level. Following unsuccessful supportive measures, the patient underwent treatment with an epidural blood patch. After the treatment, her postural headaches completely subsided without recurrence. This report underscores that IH syndrome is a rare yet clinically significant complication that may be associated with manipulation of the upper spine.

Vertebral artery dissection (VAD) is a rare but serious safety concern associated with spinal manipulative therapy. This report highlights the occurrence of such condition in a 35-year-old male without predisposing risk factors. The patient has had dizziness and occipital pain of new onset following chirotherapy for the neck spines. On admission, magnetic resonance angiography depicted a dissecting dilatation at the intracranial portion of the right vertebral artery. He was placed on antithrombotic therapy and fluid supplementation. His presenting symptoms completely remitted without recurrence. Follow-up images 4 months later showed resolution of the arterial dissection without progression to rupture. The study with featured images facilitates the physicians better understand VAD in those with neurologic complaints following chiropractic manipulation of the cervical vertebra.