No abstract available.
Anti-Infective Agents/therapeutic use ; Anti-Inflammatory Agents/therapeutic use ; *Color ; Dysuria/drug therapy ; Erythrocytes/cytology ; Humans ; Male ; Middle Aged ; Prostate-Specific Antigen/blood ; Prostatic Neoplasms/surgery ; *Urinalysis ; Urological Agents/therapeutic use

No abstract available.
Adult ; Air ; Anti-Inflammatory Agents/therapeutic use ; Antibodies, Monoclonal/*therapeutic use ; Antirheumatic Agents/therapeutic use ; Body Fluids ; Crohn Disease/diagnosis/drug therapy/*urine ; Cystitis ; Dysuria/drug therapy/*etiology ; Feces ; Humans ; Male ; *Urinalysis

We describe a 56-year-old man who developed an acute liver injury after taking alfuzosin for 1 month to control his newly diagnosed benign prostatic hypertrophy (BPH). There was no history of alcohol consumption or the taking herbal or traditional remedies. Viral causes, autoimmune hepatitis, and biliary tree obstruction were excluded. Other rare causes of hepatitis such as hemochromatosis, primary biliary cirrhosis and Wilson's disease were also absent in this patient. His liver test results began to improve after discontinuing the alfuzosin. Two weeks later, alfuzosin was administered again because the patient complained of dysuria. After 10 days of alfuzosin reuse, his liver test results worsened. Five months later after the complete discontinuation of the drug, his liver test results had returned to normal. This clinical sequence suggests that alfuzosin caused his acute liver injury.
Acute Disease ; Adrenergic alpha-Antagonists/*adverse effects ; Dysuria/pathology ; Humans ; Liver Diseases/*chemically induced/pathology ; Liver Function Tests ; Male ; Middle Aged ; Prostatic Hyperplasia/drug therapy ; Quinazolines/*adverse effects

Hemangiopericytoma is a relatively uncommon vascular tumor. It was first described by Stout and Murray in 1942. Here, we report a case of a primary prostatic hemangiopericytoma, which has been reported approximately <10 cases. This may be the first case of a prostatic hemangiopericytoma in Korea. A 35-year-old male patient presented with an episode of dysuria and perineal discomfort over the past 3 months. The radiological and histological features indicated a malignant hemangiopericytoma. Systemic chemotherapy was selected as the primary treatment. After 5 cycles of chemotherapy, the size of masses of the prostate and lung decreased. Four months after then, the patient died from hemoptysis.
Adult ; Drug Therapy ; Dysuria ; Hemangiopericytoma* ; Hemoptysis ; Humans ; Korea ; Lung ; Male ; Prostate

Hemangiopericytoma is a relatively uncommon vascular tumor. It was first described by Stout and Murray in 1942. Here, we report a case of a primary prostatic hemangiopericytoma, which has been reported approximately <10 cases. This may be the first case of a prostatic hemangiopericytoma in Korea. A 35-year-old male patient presented with an episode of dysuria and perineal discomfort over the past 3 months. The radiological and histological features indicated a malignant hemangiopericytoma. Systemic chemotherapy was selected as the primary treatment. After 5 cycles of chemotherapy, the size of masses of the prostate and lung decreased. Four months after then, the patient died from hemoptysis.
Adult ; Drug Therapy ; Dysuria ; Hemangiopericytoma* ; Hemoptysis ; Humans ; Korea ; Lung ; Male ; Prostate

We report three cases of cystinuria, presenting with urinary stones. A 2-year-old girl presented with urinary difficulty, hematuria, dysuria of sudden onset, and her 7-month-old younger brother also was presented with urinary difficulty, irritability on urination & stone passage. Other 6-month-old boy was admitted due to sudden onset anuria. They had radioopague renal & ureter stones and stone analysis revealed mixed cystine stones. The diagnosis of cystinuria was confirmed metabolic studies and stone analysis. Lrinary amino acid analysis showed excessive excretion of dibasic amino acids(cystine, ornithine, lysine, arginine). And they all had hypercalciuria and hyperuricosuria. They were treated with combination of percutaneous lithotripsy for large obstructing senes a nd an oral drug therapy with sodium bicarbonate for rendering the urine more alkaline, and alpha-mercaptopropionylglycine(ThiolaR). This form of treatment was sucessful in our three cases with elimination of recurrent nephrolithiasis, but in one patient, nephrotic syndrome possibly caused by ThiolaR was developed. The nephrotic syndrome was recovered spontaneously after cessation of Thiola. A review of literatures was also attempted briefly.
Anuria ; Child, Preschool ; Cystine ; Cystinuria* ; Diagnosis ; Drug Therapy ; Dysuria ; Female ; Hematuria ; Humans ; Hypercalciuria ; Infant ; Lithotripsy ; Lysine ; Male ; Nephrolithiasis ; Nephrotic Syndrome ; Ornithine ; Siblings ; Sodium Bicarbonate ; Tiopronin ; Ureter ; Urinary Calculi ; Urination

We retrospectively reviewed eleven patients with advanced bladder carcinoma (T3b-4) who were treated with methotrexate, vinblastine, doxorubicin and cisplatin (M-VAC) chemotherapy alone. 1. The mean age and the cycle were 64 years ( 50-75) and 4.7 cycles ( 1-II) respectively. 2. In primary lesions, four (36.4 per cent) showed partial response, six (54.5 per cent) minor response and one (9.1 per cent) clinically stable, and therefore response rate was 36.4 per cent. There was no case of complete remission. In extravesical lesions, progression was seen in a case of liver metastasis and no remarkable changes was seen in bone metastatic case. 3. Maximal effect of clinical response was observed after completion of 3-4 cycles in cases of partial remission. 4. There were marked improvement of clinical symptoms such as loss of hematuria and dysuria during 1 or 2 cycles of chemotherapy. Even though there was no case of complete remission in our cases, 3-4 cycles of M-VAC monotherapy may be considered as a kind of treatment of the advanced transitional cell carcinoma or bladder in selected cases.
Carcinoma, Transitional Cell* ; Cisplatin ; Doxorubicin ; Drug Therapy ; Dysuria ; Hematuria ; Humans ; Liver ; Methotrexate ; Neoplasm Metastasis ; Retrospective Studies ; Urinary Bladder* ; Vinblastine

A clinical observation was made on 127 patients with bladder tumor, admitted to the Department of Urology, Chonnam University Medical School Hospital during the period from January, 1979 to December, 1984. The following results were obtained: 1. There were 127 patients with bladder tumor, being 5.4 percent of a total of 2,360 in-patients during the period. 2. Of the patients with bladder tumor, 106 were males and 21 females with a ratio of 5 to 1 Ages were ranged from 6 months to 84 years with a mean age of 51.9 years and 81.1 percent of the patients being over 50 years of age. 3. The most common symptom was gross hematuria in 94.5 percent of the patients and frequency in 15.7 percent painful urination in 12.6 percent and dysuria in 10.2 percent were observed in order. Seventy four percent of the patients came with 1 year of their first trouble and only 3.1 percent delayed more than 5 years. 4. Of 124 patient, 40 (32.3 percent) had tumors in the posterior wall of the bladder and 83 (66.9 percent) had single tumor when first seen. 5. Of 114 patients on which an IVP was performed, 78 (68.4 percent) revealed normal upper urinary tracts and 85 (74.6 percent) showed filling defects in the bladder. 6. The most common of the associated diseases were hypertension in 11 cases and benign prostatic hyperplasia in 10. Concurrent transitional cell carcinoma in the renal pelvis and/or ureter or urethra were found in 11 patients (8.7 percent) of 127 patients with bladder tumor. Different malignancies developed in other organs except the bladder were associated in 10 patients (7.9 percent) of 127 patients with bladder tumor all their lives. 7. Pathologic examination of specimens from 111 cases revealed transitional cell carcinoma in 102 (91.9 percent). Classified according to the grade and stage, the most common was grade II found in 49 cases (44.2 percent) and stage A observed in 49 cases (44.2 percent). 8. A total of 155 operations, including 39 subsequent operations for recurrences was performed on 116 patients. They were 55 TUR, 36 open resection, 43 partial cystectomy, 20 total cystectomy with ileal conduit and 1 suprapubic cystostomy. 9. There were 47 recurrences in 35 (41.7 percent) of 84 patients initially operated and followed up. Of these recurrences, 24 (51.1 percent) occurred within 1 year of followup. Tumor recurrences were observed in 31 (81.6 percent) of 38 patients treated by surgery only, but in 16 (32.0%) of 50 patients treated by surgery plus intravesical chemotherapy.
Carcinoma, Transitional Cell ; Cystectomy ; Cystostomy ; Drug Therapy ; Dysuria ; Female ; Follow-Up Studies ; Hematuria ; Humans ; Hypertension ; Jeollanam-do ; Kidney Pelvis ; Male ; Prostatic Hyperplasia ; Recurrence ; Schools, Medical ; Ureter ; Urethra ; Urinary Bladder Neoplasms* ; Urinary Bladder* ; Urinary Diversion ; Urinary Tract ; Urination ; Urology

A clinical observation was made on 46 cases of renal tuberculosis who were admitted to the Department of Urology, Eul Ji General Hospital, Seoul, Korea, during the period from January 1978 to December 1982. Following results were obtained. 1. The most common symptoms were urinary frequency (47.8%), gross hematuria (43.5%) flank pain (32.6%) and dysuria (21.7%). 2. Tubercle bacilli were demonstrated in 37% of patients by Ziehl-Neelson staining. The most common findings of urine were hematuria (73.9%), Pyuria (54.4%) and proteinuria (32.6%). 3. Excretory urographic findings in 46 cases of renal tuberculosis were non visualization (45.7%), calyectasis (28.3%), delayed visualization (15.2%), ureteral deformity (10.9%). 4. The most common finding of cystoscopy was hemorrhagic patches (44.4%), followed by sealed off ureteral orifice (s) in 30.6%, ulceration and tubercle formation in 25.0%. 5. Patients were managed by chemotherapy only in 47.8%, chemotherapy with nephrectomy in 43.5%, chemotherapy with reconstructive surgery in 8.7%.
Congenital Abnormalities ; Cystoscopy ; Drug Therapy ; Dysuria ; Flank Pain ; Hematuria ; Hospitals, General ; Humans ; Korea ; Nephrectomy ; Proteinuria ; Pyuria ; Seoul ; Tuberculosis, Renal* ; Ulcer ; Ureter ; Urology

A clinical observation was made on 60 cases of genitourinary tract tuberculosis who were admitted to National Medical Center during the period from January 1976 through December 1980. Following results were obtained 1. Incidence of genitourinary tract tuberculosis was 6% of all in patients. 2. Most frequent symptoms was those of vesical symptoms such as frequency (53.3%), hematuria (55%) and dysuria (28.3%). 3. Tuberculosis in other combined with genitourinary tract tuberculosis were such as pulmonary tuberculosis (38.3%), pleurisy (5%), spine tuberculosis (3.3%) and tuberculous intestinal fistula (3.3%). 4. Tuberculous epididymitis without radiographic evidence of tuberculous invasion were 12 cases among the patients. 5. The most frequent finding of urine was pyuria (45%) , hematuria (45%) and proteinuria (33.3%). 6. Tubercle bacilli were demonstrated by staining in 26.6%. 7. Excretory urographic findings in 60 cases of renal tuberculosis were non visualization (50%). calyectasis (26.6%). delayed visualization (21.6%), ureteral abnormality (21%) and contracted bladder (15%). 8. Patients were managed by chemotherapy only in 20%, chemotherapy with nephrectomy in 38.3% and chemotherapy with reconstructive surgery in 20%.
Drug Therapy ; Dysuria ; Epididymitis ; Hematuria ; Humans ; Incidence ; Intestinal Fistula ; Male ; Nephrectomy ; Pleurisy ; Proteinuria ; Pyuria ; Spine ; Tuberculosis* ; Tuberculosis, Pulmonary ; Tuberculosis, Renal ; Ureter ; Urinary Bladder