Objective:To establish a nasal septum evaluation model before and after nasal septum deviation correction surgery with finite element analysis, to explore the effect of nasal septum cartilage stress reduction after nasal septum deviation correction surgery.Methods:In this study, a male adult patient treated in Zhujiang Hospital of Southern Medical University in January 2022 was selected for second-line nasal endoscopic tension-reduction septum correction. Three-dimensional reconstruction and finite element analysis of nasal septum cartilage were performed before surgery and 6 months after surgery, and DICOM format data of three-dimensional CT were collected. Mimics 21.0, Geomagic Studio 2014, and ANSYS Workbench 17.0 software were used to establish a three-dimensional finite element model of the nasal septum, and fixed constraints were set on the top and bottom of the nasal septum cartilage. A contact stress with a pressure of 10 6 Pa along the X axis was applied in the front plane of the cartilage, and then the finite element analysis of the total deformation displacement and von Mises stress (VMS) distribution of the nasal septum was performed. Results:(1) The maximum value of the total deformation displacement of the deviated nasal septum cartilage was located in the front of the cartilage, and the maximum value was 0.022 296 m before surgery and 0.108 810 m after surgery. (2) The stress distribution of deviated nasal septum cartilage was mainly concentrated in the anterior cartilage, in which VMS had a peak at the anterior end of the nasal septum, and the VMS peak was 725 000 Pa before surgery and 2 426 000 Pa after surgery. (3) The total deformation displacement and VMS value curves of the nasal septum showed a "waterfall" drop from the anterior end of the nasal septum to the posterior end. (4) The maximum distribution range of VMS in the nasal septum was 0.003 252 4 m 2 before surgery and 0.000 418 6 m 2 after surgery, indicating that the stress distribution range of the nasal septum after surgery was significantly reduced compared with that before surgery. Conclusion:The three-dimensional finite element model of nasal septum is established successfully through CT three-dimensional reconstruction and finite element analysis. By comparing the total deformation displacement and VMS curve before and after the operation, this model evidenced that the correction of nasal deviation has the effect of reducing the stress of nasal septum cartilage.

Objective:To establish a nasal septum evaluation model before and after nasal septum deviation correction surgery with finite element analysis, to explore the effect of nasal septum cartilage stress reduction after nasal septum deviation correction surgery.Methods:In this study, a male adult patient treated in Zhujiang Hospital of Southern Medical University in January 2022 was selected for second-line nasal endoscopic tension-reduction septum correction. Three-dimensional reconstruction and finite element analysis of nasal septum cartilage were performed before surgery and 6 months after surgery, and DICOM format data of three-dimensional CT were collected. Mimics 21.0, Geomagic Studio 2014, and ANSYS Workbench 17.0 software were used to establish a three-dimensional finite element model of the nasal septum, and fixed constraints were set on the top and bottom of the nasal septum cartilage. A contact stress with a pressure of 10 6 Pa along the X axis was applied in the front plane of the cartilage, and then the finite element analysis of the total deformation displacement and von Mises stress (VMS) distribution of the nasal septum was performed. Results:(1) The maximum value of the total deformation displacement of the deviated nasal septum cartilage was located in the front of the cartilage, and the maximum value was 0.022 296 m before surgery and 0.108 810 m after surgery. (2) The stress distribution of deviated nasal septum cartilage was mainly concentrated in the anterior cartilage, in which VMS had a peak at the anterior end of the nasal septum, and the VMS peak was 725 000 Pa before surgery and 2 426 000 Pa after surgery. (3) The total deformation displacement and VMS value curves of the nasal septum showed a "waterfall" drop from the anterior end of the nasal septum to the posterior end. (4) The maximum distribution range of VMS in the nasal septum was 0.003 252 4 m 2 before surgery and 0.000 418 6 m 2 after surgery, indicating that the stress distribution range of the nasal septum after surgery was significantly reduced compared with that before surgery. Conclusion:The three-dimensional finite element model of nasal septum is established successfully through CT three-dimensional reconstruction and finite element analysis. By comparing the total deformation displacement and VMS curve before and after the operation, this model evidenced that the correction of nasal deviation has the effect of reducing the stress of nasal septum cartilage.

Objective To investigate the role of network platform for treatment and rescue of acute and severe cerebrovascular diseases in improving treatment level of patients with acute ischemic stroke.Methods The differences of number of patients accepted venous thrombolysis, number of patients accepted emergency intravascular interventional treatment, and time from admission to intravenous thrombolysis (door to needle time [DNT]) were analyzed in patients with acute ischemic stroke admitted to our hospital in the first year (2016) and the second and third years (2017 and 2018) of construction of network platform for treatment and rescue of acute and severe cerebrovascular diseases in Yunfu city. The National Institutes of Health Stroke Scale (NIHSS) scores were compared in 120 patients selected randomly from online referral (study group,n=60) and non-online referral (control group,n=60) within the same time periods in 2018.Results In 2017 and 2018, the number of patients accepted intravenous thrombolysis was 85 and 103, respectively, and the rate of intravenous thrombolysis was 9.92％ and 9.83％; they were all significantly larger/higher than those in 2016 (n=50, 6.97％,P<0.05). In 2017 and 2018, the number of patients accepted emergency endovascular treatment was 56 and 129, respectively, and the emergency endovascular treatment rate was 6.53％ and 12.31％; they were all higher than those in 2016 (n=44 and 6.14％), and the differences between those in 2018 and 2016 were statistically significant (P<0.05). The DNT ([82.00±18.75] min in 2017 and [77.00±32.17] min in 2018) was significantly shorter than that in 2016 ([109.00±30.58] min,P<0.05). The NIHSS scores of the study group and control group were 4.70±3.64 and 8.90±5.62, respectively, after one week of treatment, both of which were lower than those before treatment (14.30±6.29 and 13.60±6.37); and after treatment, the NIHSS scores of the treatment group were statistically lower than those of the control group (P<0.05). Conclusion Construction and effective operation of network platform for treatment and rescue of acute and severe cerebrovascular diseases is an effective guarantee to improve the success rate of treatment for patients with acute ischemic stroke.