1.Utility of white matter to gray matter signal intensity ratio in comatose patients treated by targeted temperature management after cardiac arrest: a preliminary study
Kyoung Tak KEUM ; Yong Hwan KIM ; Seong Youn HWANG ; Jun Ho LEE ; Dong Woo LEE ; Yun Gyu SONG ; Jung Hwa LEE ; Kyoung Yul LEE
Journal of the Korean Society of Emergency Medicine 2019;30(5):437-445
OBJECTIVE: This study examined the efficacy of the white matter (WM) to gray matter (GM) signal intensity ratio (SIR) in predicting the clinical prognosis of cardiac arrest patients. METHODS: Thirty-one patients who were resuscitated from cardiac arrest and underwent brain magnetic resonance imaging (MRI) were investigated retrospectively. Thirty one subjects with normal brain MRI findings served as the controls. The signal intensities (SI) were measured on T2-weighted image (T2WI). The circular regions of measurement (2–10 mm²) were placed over the regions of interest, and the average signals in GM and WM were recorded in the caudate nucleus (CN), putamen, anterior limb of the internal capsule, corpus callosum (CC), and in the cortex and WM of the frontal lobe. Cerebral performance category (CPC) 1–2 were classified as a good prognosis, and CPC 3–5 were classified as a poor prognosis. RESULTS: Most combinations of the SIR of WM to GM and most SIs of GM, except the frontal cortex, were significantly different between the two groups. On the other hand, the SI of WM was insignificant between both groups. In receiver operating characteristic (ROC) curve analysis, the SIR of the CC to CN had an area under the ROC curve (AUROC) of 1.00 for a cut-off value of 1.59 (sensitivity, 100%; specificity, 100%), the SIR of the CC to putamen had also an AUROC of 1.00 for a cut-off value of 1.43 (sensitivity, 100%; specificity, 100%). CONCLUSION: The SIR of WM to GM measured on a T2WI is related to the neurological outcome after a cardiac arrest.
Brain
;
Caudate Nucleus
;
Coma
;
Corpus Callosum
;
Extremities
;
Frontal Lobe
;
Gray Matter
;
Hand
;
Heart Arrest
;
Humans
;
Internal Capsule
;
Magnetic Resonance Imaging
;
Prognosis
;
Putamen
;
Retrospective Studies
;
ROC Curve
;
Sensitivity and Specificity
;
White Matter
2.Malignant Transformation of Pulmonary Benign Metastasizing Leiomyoma.
Kyung Sub SONG ; Dong Yoon KEUM ; Il Seon HWANG
The Korean Journal of Thoracic and Cardiovascular Surgery 2017;50(1):59-63
Pulmonary benign metastasizing leiomyoma (PBML) is defined as metastasis of a leiomyoma to lung tissue. It was first reported in 1937. P BML is known as a benign disease, but can undergo malignant transformation. Only 1 case of the malignant transformation of PBML to leiomyosarcoma has been reported previously. In this report, we present a case of malignant transformation of PBML.
Leiomyoma*
;
Leiomyosarcoma
;
Lung
;
Lung Neoplasms
;
Neoplasm Metastasis
3.Quality Indicators for Small Bowel Capsule Endoscopy.
Ki Nam SHIM ; Seong Ran JEON ; Hyun Joo JANG ; Jinsu KIM ; Yun Jeong LIM ; Kyeong Ok KIM ; Hyun Joo SONG ; Hyun Seok LEE ; Jae Jun PARK ; Ji Hyun KIM ; Jaeyoung CHUN ; Soo Jung PARK ; Dong Hoon YANG ; Yang Won MIN ; Bora KEUM ; Bo In LEE
Clinical Endoscopy 2017;50(2):148-160
Capsule endoscopy (CE) enables evaluation of the entire mucosal surface of the small bowel (SB), which is one of the most important steps for evaluating obscure gastrointestinal bleeding. Although the diagnostic yield of SB CE depends on many clinical factors, there are no reports on quality indicators. Thus, the Korean Gut Image Study Group (KGISG) publishes an article titled, “Quality Indicators for Small Bowel Capsule Endoscopy” under approval from the Korean Society of Gastrointestinal Endoscopy (KSGE). Herein, we initially identified process quality indicators, while the structural and outcome indicators are reserved until sufficient clinical data are accumulated. We believe that outcomes of SB CE can be improved by trying to meet our proposed quality indicators.
Capsule Endoscopy*
;
Endoscopy, Gastrointestinal
;
Hemorrhage
4.The Association between Sleep Duration and Hypertension in Non-obese Premenopausal Women in Korea.
Mi Yeon SONG ; En SUNG ; Seung Pil JUNG ; Keun Mi LEE ; Shin Ho KEUM ; Sun Dong RYU
Korean Journal of Family Medicine 2016;37(2):130-134
BACKGROUND: Previous studies have revealed that sleep duration is linked to both obesity and hypertension. Here, we evaluated the association between sleep duration and hypertension in obese and non-obese premenopausal women using representative national survey data from the Korean population. METHODS: A total of 4,748 subjects over 20 years of age from the Korean National Health and Nutrition Examination Survey from 2010 to 2012 were included. To control for risk factors, multivariable logistic regression was used to calculate the adjusted odds ratios and 95% confidence intervals of hypertension across the following sleep duration categories: <6, 6-8, and >8 h/d. RESULTS: Among the participants, 367 subjects (7.7%) had hypertension. Their mean sleep duration was 7 hours. In the non-obese subjects, after controlling for potential confounding variables, the odds ratio for hypertension was 1.86 fold greater in those with a sleep duration of <6 hours (odds ratio, 1.79; 95% confidence interval, 1.05 to 3.03) as compared to those who slept for 6.8 hours. However, there was no association between sleep duration and the risk of hypertension in obese subjects. Long sleep duration (over 8 h/d) was not associated with hypertension in either the non-obese or the obese subjects in this study. CONCLUSION: Short sleep duration (less than 6 h/d) may be a significant risk factor for hypertension in non-obese premenopausal women. However, there is no association between sleep duration and the risk of hypertension in obese women.
Confounding Factors (Epidemiology)
;
Female
;
Humans
;
Hypertension*
;
Korea*
;
Logistic Models
;
Nutrition Surveys
;
Obesity
;
Odds Ratio
;
Risk Factors
5.Safety and Feasibility of Self-Expandable Metallic Stent Insertion for the Right-Side Colonic Malignant Obstruction and Its Clinical Benefits.
Seok Hwan CHOI ; Jung Myun KWAK ; Dong Woo KANG ; Han Deok KWAK ; Nak Song SUNG ; Bo ra KEUM ; Eun Sun KIM ; Jin KIM ; Seon Hahn KIM
Journal of Minimally Invasive Surgery 2015;18(1):19-23
PURPOSE: The efficacy of stenting for the right-side colonic malignant obstruction is unknown. The purpose of this study was to evaluate the safety and feasibility of self-expandable metallic stent insertion for the right-side colonic malignant obstruction and its clinical benefits. METHODS: We retrospectively reviewed clinical data from 460 patients who underwent right hemicolectomy for right-side colon cancer from January 2006 to January 2014 at Korea University Anam Hospital. Twenty four patients who developed malignant obstruction in the right -side colon were identified and analyzed. RESULTS: Self-expandable metallic stent insertion was attempted in 14 patients, and initial technical success was achieved in 13 patients (92.9%). No immediate stent-related complications were reported. Complete relief of obstruction was achieved in all of the 13 patients. Eleven patients who failed stenting underwent emergency operation. All of the 13 patients with stent underwent laparoscopic surgery and only one case was converted to open. Only three patients in the emergency group underwent laparoscopic surgery but one was converted. Operative time and number of retrieved lymph nodes did not differ between the two groups. Postoperative hospital stay (9.8+/-3.2 in stent group vs. 16.3+/-10.9 days in emergency group, p=0.082) tended to be shorter in the stent group. Estimated blood loss (38.5+/-138.7 in stent group vs. 381.8+/-411.9 in emergency group, p=0.010) and duration for resuming diet (3.2+/-2.2 in stent group vs. 6.6+/-7.0 days in emergency group, p=0.017) were significantly better in the stent group. CONCLUSION: Self-expandable metallic stent appears to be safe and feasible in the right-side colonic malignant obstruction. It facilitates minimally invasive surgery and may result in better short-term surgical outcome.
Colon*
;
Colonic Neoplasms
;
Diet
;
Emergencies
;
Humans
;
Korea
;
Laparoscopy
;
Length of Stay
;
Lymph Nodes
;
Operative Time
;
Retrospective Studies
;
Stents*
;
Surgical Procedures, Minimally Invasive
6.Sero-surveillance of Transmissible Gastroenteritis Virus (TGEV) and Porcine Respiratory Coronavirus (PRCV) in South Korea.
Yoon I OH ; Dong Kun YANG ; Soo Dong CHO ; Hee Kyung KANG ; Sun Keum CHOI ; Ye Jee KIM ; Bang Hun HYUN ; Jae Young SONG
Journal of Bacteriology and Virology 2011;41(3):189-193
Transmissible gastroenteritis (TGE) is sporadic in South Korea. Since porcine respiratory coronavirus (PRCV) infection was identified in South Korea in 1996, the TGE infection has decreased with the PRCV occurrence. In this study, we described the sero-surveillance of TGE/PRCV infection by using a commercially available ELISA kit. A total of 1,295 sera from slaughtered pigs and 69 sera from wild boars were collected in years 2009 and 2010 throughout the country and tested for antibodies against TGE and PRCV. Although there was no clinical sign observed for TGE and vaccination had not been done for TGEV, 4.9% of sera showed positive for antibody against TGEV. Furthermore, 63.7% of finisher and 8.7% of wild boars were positive for antibody against PRCV. Our result suggests that the TGEV infection might still be present in some farms in South Korea.
Antibodies
;
Enzyme-Linked Immunosorbent Assay
;
Gastroenteritis
;
Porcine Respiratory Coronavirus
;
Republic of Korea
;
Sus scrofa
;
Swine
;
Transmissible gastroenteritis virus
;
Vaccination
7.Comparison of echocardiography, magnetic resonance imaging, and multidetector CT Images of a Cor Triatriatum.
Jeong Whan CHO ; In Wook SONG ; Jong Seon PARK ; Keum Rae KIM ; Sang Hee LEE ; Dong Gu SHIN ; Geu Ru HONG
Korean Journal of Medicine 2010;78(2):189-190
No abstract available.
Cor Triatriatum
;
Echocardiography
;
Magnetic Resonance Imaging
;
Magnetic Resonance Spectroscopy
;
Magnetics
;
Magnets
8.Aberrant right coronary artery from the left coronary sinus with an interarterial course detected using 128-multidetector coronary CT angiography.
In Wook SONG ; Jong Seon PARK ; Keum Rae KIM ; Dong Gu SHIN ; Bong Sup SHIM ; Geu Ru HONG ; Young Jo KIM
Korean Journal of Medicine 2009;77(5):571-572
No abstract available.
Angiography
;
Coronary Sinus
;
Coronary Vessels
9.A case of Hypertensive Encephalopathy after cesarean section.
Korean Journal of Obstetrics and Gynecology 2006;49(1):188-193
Hypertensive encephalopathy is usually defined as malignant hypertension associated with central nervous system abnormalities such as headache, seizure, hypertension, altered consciousness, increased intracranial pressure, and retinopathy. The pathogenesis of hypertensive encephalopathy is uncompletely understood, although it seems to be related to hypertensive cerebrovascular endothelial dysfunction, disruption of the blood-brain barrier with increased permeability, cerebral edema, and microhemorrhage formation. Magnetic resonance imaging shows a characteristic posterior leukoencephalopathy that predominantly affects the white matter of the parieto-occipital regions. Hypertensive encephalopathy is a rare manifestation of hypertensive emergency that requires proper diagnosis and management to avoid a irreversible brain damage. We report a patient who developed hypertensive encephalopathy after cesarean section without preeclampsia or chronic hypertension and a case presented with a brief review of the literatures.
Blood-Brain Barrier
;
Brain
;
Brain Edema
;
Central Nervous System
;
Cesarean Section*
;
Consciousness
;
Diagnosis
;
Emergencies
;
Female
;
Headache
;
Humans
;
Hypertension
;
Hypertension, Malignant
;
Hypertensive Encephalopathy*
;
Intracranial Pressure
;
Leukoencephalopathies
;
Magnetic Resonance Imaging
;
Permeability
;
Pre-Eclampsia
;
Pregnancy
;
Seizures
10.Comparison of Hospital stay and Cost-effectiveness between Treatment Modalities in Ectopic Pregnancy.
Chung Hee HAN ; Mi Jin AHN ; An Na NAM ; Ji Young LEE ; Dong Ki JEOUNG ; Dong Keum SONG ; Byung Woo JANG ; Kyong Jin KIM ; Sung Ki LEE
Korean Journal of Obstetrics and Gynecology 2004;47(8):1518-1524
OBJECTIVE: The purpose of this study was to compare the hospital stay and cost-effectiveness between treatment modalities in ectopic pregnancy for proper management. METHODS: In this study, the authors studied 121 cases retrospectively who had been admitted and treated at Department of Obstetrics and Gynecology, Konyang University Hospital from February 1, 2000 to August 31, 2003. We analyzed clinical features, treatment modality, hospital stay and cost-effectiveness between each groups. One-way ANOVA test was used and p<0.05 was regarded as statistically significant. RESULTS: There was no difference in clinical features between treatment modalites. Of total 121 cases, operative procedures were done in 105 cases (explo-laparotomy in 58, laparoscopy in 43, dilatation and curettage in 4) and medical treatment in 16 cases (Multiple dose methotrexate protocol in 11, Single dose methotrexate protocol in 5). Average of length of hospital stay was 5.3 +/- 0.2 days in explo-laparotomy, 3.8 +/- 0.2 days in laparoscopy, 2.8 +/- 1.4 days in dilatation and curettage, 6.5 +/- 0.5 days in multiple dose methotrexate protocol, 2.4 +/- 0.4 days in single dose methotrexate protocol. According to treatment modality, there was significant difference in total cost and cost sharing. Total cost in explo-laparotomy (875,324 +/- 25,977 Won) was more expensive than that of laparoscopy (734,375 +/- 35,179 Won). But, cost sharing in explo-laparotomy (156,543 +/- 9,583 Won) was less expensive than laparoscopy (319,493 +/- 26,255 Won). Total cost and cost sharing in multiple dose methotrexate protocol (323,231 +/- 33,972 Won, 184,465 +/- 17,344 Won) was more expensive than that of Single methotrexate protocol (192,495 +/- 31,180 Won, 68,793 +/- 13,422 Won). CONCLUSION: Based on these results, it is very important that we should have an interest in ectopic pregnancy for early detection and proper management. Consequently, Achievement of precise decision and successful methotrexate treatment can be possible to decrease hospital stay and cost-effectiveness.
Cost Sharing
;
Dilatation and Curettage
;
Female
;
Gynecology
;
Laparoscopy
;
Length of Stay*
;
Methotrexate
;
Obstetrics
;
Pregnancy
;
Pregnancy, Ectopic*
;
Retrospective Studies
;
Surgical Procedures, Operative

Result Analysis
Print
Save
E-mail