1.Potential predictors for chemotherapeutic response and prognosis in epithelial ovarian, fallopian tube and primary peritoneal cancer patients treated with platinum-based chemotherapy
Dhammapoj JEERAKORNPASSAWAT ; Prapaporn SUPRASERT
Obstetrics & Gynecology Science 2020;63(1):55-63
		                        		
		                        			
		                        			3.38, PLR >210, CA125 >365, advanced stage, suboptimal disease, serous type, and ascites were significant predictive factors for platinum resistance. However, only NLR >3.38 and advanced stage were independent predictive factors with an adjusted odds ratio of 1.880 and 3.333, respectively. Regarding factors associated with poor survival outcomes, only PLR >210 and advanced stage were independent factors, with a hazard ratio of 1.578 and 3.994, respectively.CONCLUSION: High NLR and advanced stage were potential independent predictive factors for platinum resistance, whereas high PLR and advanced stage were potential independent predictive factors for poor survival outcomes.]]>
		                        		
		                        		
		                        		
		                        			Ascites
		                        			;
		                        		
		                        			Blood Platelets
		                        			;
		                        		
		                        			Drug Therapy
		                        			;
		                        		
		                        			Fallopian Tubes
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Lymphocytes
		                        			;
		                        		
		                        			Medical Records
		                        			;
		                        		
		                        			Multivariate Analysis
		                        			;
		                        		
		                        			Neutrophils
		                        			;
		                        		
		                        			Odds Ratio
		                        			;
		                        		
		                        			Ovarian Neoplasms
		                        			;
		                        		
		                        			Platinum
		                        			;
		                        		
		                        			Prognosis
		                        			;
		                        		
		                        			Retrospective Studies
		                        			;
		                        		
		                        			ROC Curve
		                        			
		                        		
		                        	
            
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