1.Maxillary sinus floor augmentation: a review of current evidence on anatomical factors and a decision tree.
Mingyue LYU ; Dingyi XU ; Xiaohan ZHANG ; Quan YUAN
International Journal of Oral Science 2023;15(1):41-41
Maxillary sinus floor augmentation using lateral window and crestal technique is considered as predictable methods to increase the residual bone height; however, this surgery is commonly complicated by Schneiderian membrane perforation, which is closely related to anatomical factors. This article aimed to assess anatomical factors on successful augmentation procedures. After review of the current evidence on sinus augmentation techniques, anatomical factors related to the stretching potential of Schneiderian membrane were assessed and a decision tree for the rational choice of surgical approaches was proposed. Schneiderian membrane perforation might occur when local tension exceeds its stretching potential, which is closely related to anatomical variations of the maxillary sinus. Choice of a surgical approach and clinical outcomes are influenced by the stretching potential of Schneiderian membrane. In addition to the residual bone height, clinicians should also consider the stretching potential affected by the membrane health condition, the contours of the maxillary sinus, and the presence of antral septa when evaluating the choice of surgical approaches and clinical outcomes.
Sinus Floor Augmentation
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Decision Trees
3.A prospective study of the decision tree prediction model for attention deficit hyperactivity disorder in preschool children.
Xin-Xin HUANG ; Ping OU ; Qin-Fang QIAN ; Yan HUANG ; Yan-Xia WANG
Chinese Journal of Contemporary Pediatrics 2022;24(3):255-260
OBJECTIVES:
To study the clinical value of attention time combined with behavior scale in the screening of attention deficit hyperactivity disorder (ADHD) in preschool children.
METHODS:
A total of 200 preschool children with ADHD diagnosed in Fujian Maternal and Child Health Hospital from February 2019 to March 2020 were enrolled as the ADHD group. A total of 200 children who underwent physical examination in the hospital or kindergartens during the same period were enrolled as the control group. Attention time was recorded. Chinese Version of Swanson Nolan and Pelham, Version IV Scale-Parent Form (SNAP-IV) scale was used to evaluate symptoms. With clinical diagnosis as the gold standard, the decision tree analysis was used to evaluate the clinical value of attention time combined with behavior scale in the screening of ADHD.
RESULTS:
Compared with the control group, the ADHD group had significantly higher scores of SNAP-IV items 1, 4, 7, 8, 10, 11, 14, 15, 16, 18, 20, 21, and 22 (P<0.05) and a significantly shorter attention time (P<0.05). The variables with statistically significant differences between the two groups in univariate analysis were used as independent variables to establish a decision tree model. The accuracy of the model in predicting ADHD was 81%, that in predicting non-ADHD was 69%, and the overall accuracy was 75%, with an area under the ROC curve of 0.816 (95% CI: 0.774-0.857, P<0.001).
CONCLUSIONS
The decision tree model for screening ADHD in preschool children based on attention time and assessment results of behavior scale has a high accuracy and can be used for rapid screening of ADHD among children in clinical practice.
Asians
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Attention Deficit Disorder with Hyperactivity/diagnosis*
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Child, Preschool
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Decision Trees
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Humans
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Mass Screening
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Prospective Studies
4.Analysis on influencing factors of HBV intrauterine transmission based on integration of decision tree model and logistic regression model.
Wen Xin CHEN ; Cong JIN ; Ting WANG ; Yan Di LI ; Shu Ying FENG ; Bo WANG ; Yong Liang FENG ; Su Ping WANG
Chinese Journal of Epidemiology 2022;43(1):85-91
Objective: To investigate the influencing factors of HBV intrauterine transmission and their interaction effects by integrating logistic regression model and Chi-squared automatic interaction detector (CHAID) decision tree model. Methods: A total of 689 pairs of HBsAg-positive mothers and their neonates in the obstetrics department of the Third People's Hospital of Taiyuan from 2007 to 2013 were enrolled, and the basic information of mothers and their neonates were obtained by questionnaire survey and medical record review, such as the general demographic characteristics, gestational week and delivery mode. HBV DNA and HBV serological markers of the mothers and newborns were detected by fluorescence quantitative PCR and electrochemiluminescence immunoassay respectively. The CHAID decision tree model and unconditional logistic regression analysis were used to explore the factors influencing HBV intrauterine transmission in neonates of HBsAg-positive mothers. Results: Among the 689 neonates, the incidence of HBV intrauterine transmission was 11.47% (79/689). After adjusted for confounding factors, the first and second logistic multivariate analysis showed that cesarean delivery was a protective factor for HBV intrauterine transmission (OR=0.25, 95%CI: 0.14-0.43; OR=0.27, 95%CI: 0.15-0.46); both models indicated that maternal HBeAg positivity and HBV DNA load ≥2×105 IU/ml before delivery were risk factors of HBV intrauterine transmission (OR=3.89, 95%CI: 2.32-6.51; OR=3.48, 95%CI: 2.12-5.71), respectively. The CHAID decision tree model screened three significant factors influencing HBV intrauterine transmission, the most significant one was maternal HBeAg status, followed by delivery mode and maternal HBV DNA load. There were interactions between maternal HBeAg status and delivery modes, as well as delivery mode and maternal HBV DNA load before delivery. The rate of HBV intrauterine transmission in newborns of HBeAg-positive mothers by vaginal delivery increased from 19.08% to 29.37%; among HBeAg-positive mothers with HBV DNA ≥2×105 IU/ml, the rate of HBV intrauterine transmission increased to 33.33% in the newborns by vaginal delivery. Conclusions: Maternal HBeAg positivity,maternal HBV DNA ≥2×105 IU/ml and vaginal delivery could be risk factors for HBV intrauterine transmission in newborns. Interaction effects were found between maternal HBeAg positivity and vaginal delivery, as well as vaginal delivery and high maternal HBV DNA load. Logistic regression model and the CHAID decision tree model can be used in conjunction to identify the high-risk populations and develop preventive strategies accurately.
DNA, Viral/genetics*
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Decision Trees
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Female
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Hepatitis B Surface Antigens
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Hepatitis B e Antigens
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Hepatitis B virus/genetics*
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Humans
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Infant, Newborn
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Infectious Disease Transmission, Vertical
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Logistic Models
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Mothers
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Pregnancy
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Pregnancy Complications, Infectious/epidemiology*
5.Estimating the Health and Economic Outcomes of the Prevention of Mother-to-child Transmission of HIV Using a Decision Tree Model.
Shui Ling QU ; Ai Ling WANG ; Xiao Ping PAN ; Qian WANG ; Li Xia DOU ; Tong ZHANG
Biomedical and Environmental Sciences 2019;32(1):68-74
Adolescent
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Adult
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Child
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Decision Trees
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Female
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HIV Infections
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economics
;
transmission
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Humans
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Infectious Disease Transmission, Vertical
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economics
;
prevention & control
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Kenya
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Middle Aged
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Mothers
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South Africa
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Vietnam
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Young Adult
6.A Prediction Model of Factors related to Career Maturity in Korean High School Students
Child Health Nursing Research 2019;25(2):95-102
PURPOSE: The purpose of this study was to identify factors associated with career maturity among Korean high school students. METHODS: A descriptive cross-sectional design was adopted using secondary data from the 2012 Korean Welfare Panel Study (KoWePS). The participants were 496 high school students who completed the supplemental survey for children, which included items on career maturity, self-esteem, study stress, teacher attachment, relationship with parents, peer attachment, depression and anxiety. Descriptive statistics, the chi-square-test, the t-test, and a decision tree were used for data analysis. RESULTS: The decision tree identified five final nodes predicting career maturity after forcing self-esteem as the first variable. The highest predicted rate of high career maturity was associated with high self-esteem, experience of career counseling, and high teacher attachment. The lowest predicted rate of high career maturity was associated with low self-esteem and low attachment to friends. CONCLUSION: Factors influencing career maturity were varied by levels of self-esteem in Korean high school students. Thus, it is necessary to develop different approaches to enhance career maturity according to levels of self-esteem.
Adolescent
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Anxiety
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Child
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Decision Trees
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Depression
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Friends
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Humans
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Parents
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Self Concept
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Statistics as Topic
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Vocational Guidance
7.Cost-Effectiveness Analysis for National Dyslipidemia Screening Program in Korea: Results of Best Case Scenario Analysis Using a Markov Model
Jae Hyun KIM ; Eun Cheol PARK ; Tae Hyun KIM ; Chung Mo NAM ; Sung Youn CHUN ; Tae Hoon LEE ; Sohee PARK
Health Policy and Management 2019;29(3):357-367
BACKGROUND: This study evaluated the cost-effectiveness of 21 different national dyslipidemia screening strategies according to total cholesterol (TC) cutoff and screening interval among 40 years or more for the primary prevention of coronary heart disease over a lifetime in Korea, from a societal perspective. METHODS: A decision tree was used to estimate disease detection with the 21 different screening strategies, while a Markov model was used to model disease progression until death, quality-adjusted life years (QALYs) and costs from a Korea societal perspective. RESULTS: The results showed that the strategy with TC 200 mg/dL and 4-year interval cost ₩4,625,446 for 16.65105 QALYs per person and strategy with TC 200 mg/dL and 3-year interval cost ₩4,691,771 for 16.65164 QALYs compared with ₩3,061,371 for 16.59877 QALYs for strategy with no screening. The incremental cost-effectiveness ratio of strategy with TC 200 mg/dL and 4-year interval versus strategy with no screening was ₩29,916,271/QALY. At a Korea willingness-to-pay threshold of ₩30,500,000/QALY, strategy with TC 200 mg/dL and 4-year interval is cost-effective compared with strategy with no screening. Sensitivity analyses showed that results were robust to reasonable variations in model parameters. CONCLUSION: In this study, revised national dyslipidemia screening strategy with TC 200 mg/dL and 4-year interval could be a cost-effective option. A better understanding of the Korean dyslipidemia population may be necessary to aid in future efforts to improve dyslipidemia diagnosis and management.
Cholesterol
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Coronary Disease
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Cost-Benefit Analysis
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Decision Trees
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Diagnosis
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Disease Progression
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Dyslipidemias
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Humans
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Korea
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Mass Screening
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Primary Prevention
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Quality-Adjusted Life Years
8.Identification of High-risk Groups of Suicide from the Depressed Elderly using Decision Tree Analysis
Journal of Korean Academy of Community Health Nursing 2019;30(2):130-140
PURPOSE: The aim of this study is to explore levels of suicidal ideation and identify subgroups of high suicidal risk among the depressed elderly in Korea. METHODS: A descriptive cross-sectional design was adopted on secondary data from the 6th (1st year) Korean national health and nutrition examination survey (KNHANES). A total of 239 depressed elders aged 60 or over who participated in the KNHANES. The prevalence of suicidal ideation and its related factors, including sociodemographic, physical, psychological characteristics and quality of life (EQ-5D index) were examined. Descriptive statistics and a decision tree analysis were performed using the SPSS/WIN 23.0 and SPSS Modeler 14.2 programs. RESULTS: Of the depressed elderly, 28.9% had suicidal ideation. Three groups with high suicidal ideation were identified. Predictive factors included perceived stress level, household income level, quality of life and restriction of activity. In the highest risk group were those depressed elderly with moderate and low levels of stress, less than .71 of EQ-5D index and restriction of activity, and 80.0% of these participants had suicidal ideation. The accuracy of the model was 80.8%, its sensitivity 85.9%, and its specificity 68.1%. CONCLUSION: Multi-dimensional intervention should be designed to decrease suicide among the depressed elderly, particularly focusing on subgroups with high risk factors. This research is expected to contribute itself to the policy design and solution building in the future as it suggests policy implications in preventing the suicide of the depressed elderly.
Aged
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Decision Trees
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Depression
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Family Characteristics
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Humans
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Korea
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Nutrition Surveys
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Prevalence
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Quality of Life
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Risk Factors
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Sensitivity and Specificity
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Suicidal Ideation
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Suicide
9.Development and Evaluation of Electronic Health Record Data-Driven Predictive Models for Pressure Ulcers
Seul Ki PARK ; Hyeoun Ae PARK ; Hee HWANG
Journal of Korean Academy of Nursing 2019;49(5):575-585
PURPOSE: The purpose of this study was to develop predictive models for pressure ulcer incidence using electronic health record (EHR) data and to compare their predictive validity performance indicators with that of the Braden Scale used in the study hospital. METHODS: A retrospective case-control study was conducted in a tertiary teaching hospital in Korea. Data of 202 pressure ulcer patients and 14,705 non-pressure ulcer patients admitted between January 2015 and May 2016 were extracted from the EHRs. Three predictive models for pressure ulcer incidence were developed using logistic regression, Cox proportional hazards regression, and decision tree modeling. The predictive validity performance indicators of the three models were compared with those of the Braden Scale. RESULTS: The logistic regression model was most efficient with a high area under the receiver operating characteristics curve (AUC) estimate of 0.97, followed by the decision tree model (AUC 0.95), Cox proportional hazards regression model (AUC 0.95), and the Braden Scale (AUC 0.82). Decreased mobility was the most significant factor in the logistic regression and Cox proportional hazards models, and the endotracheal tube was the most important factor in the decision tree model. CONCLUSION: Predictive validity performance indicators of the Braden Scale were lower than those of the logistic regression, Cox proportional hazards regression, and decision tree models. The models developed in this study can be used to develop a clinical decision support system that automatically assesses risk for pressure ulcers to aid nurses.
Case-Control Studies
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Data Mining
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Decision Support Systems, Clinical
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Decision Trees
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Electronic Health Records
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Hospitals, Teaching
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Humans
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Incidence
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Korea
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Logistic Models
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Patient Safety
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Pressure Ulcer
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Proportional Hazards Models
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Retrospective Studies
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ROC Curve
;
Ulcer
10.Machine-Learning Based Automatic and Real-time Detection of Mouse Scratching Behaviors
Ingyu PARK ; Kyeongho LEE ; Kausik BISHAYEE ; Hong Jin JEON ; Hyosang LEE ; Unjoo LEE
Experimental Neurobiology 2019;28(1):54-61
Scratching is a main behavioral response accompanied by acute and chronic itch conditions, and has been quantified as an objective correlate to assess itch in studies using laboratory animals. Scratching has been counted mostly by human annotators, which is a time-consuming and laborious process. It has been attempted to develop automated scoring methods using various strategies, but they often require specialized equipment, costly software, or implantation of device which may disturb animal behaviors. To complement limitations of those methods, we have adapted machine learning-based strategy to develop a novel automated and real-time method detecting mouse scratching from experimental movies captured using monochrome cameras such as a webcam. Scratching is identified by characteristic changes in pixels, body position, and body size by frame as well as the size of body. To build a training model, a novel two-step J48 decision tree-inducing algorithm along with a C4.5 post-pruning algorithm was applied to three 30-min video recordings in which a mouse exhibits scratching following an intradermal injection of a pruritogen, and the resultant frames were then used for the next round of training. The trained method exhibited, on average, a sensitivity and specificity of 95.19% and 92.96%, respectively, in a performance test with five new recordings. This result suggests that it can be used as a non-invasive, automated and objective tool to measure mouse scratching from video recordings captured in general experimental settings, permitting rapid and accurate analysis of scratching for preclinical studies and high throughput drug screening.
Animals
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Animals, Laboratory
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Behavior, Animal
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Body Size
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Complement System Proteins
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Decision Trees
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Drug Evaluation, Preclinical
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Humans
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Injections, Intradermal
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Machine Learning
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Methods
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Mice
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Motion Pictures as Topic
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Pruritus
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Research Design
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Sensitivity and Specificity
;
Video Recording

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