Spinal cord injury often leads to permanent disability or death,which can cause heavy burden to the family and society.Currently,there is no cure for spinal cord injury,the main purpose of the treatment is to preserve the residual function of the spinal cord to the greatest extent.In this review,the recent advances of the therapy of spinal cord injury will be elaborated in two aspects,including the neuroprotection and the neuranagenesis,and the past treatment strategies will be reassessed,in order to strengthen the understanding of the treatment of spinal cord injury,so as to provide a reference for the formulation of more effective clinical therapy.