Objective To investigate the sleep quality of in vitro fertilization and embryo transfer ( IVF-ET)patients.Methods A total of 92 patients were selected and accepted fertility treatment from October to November, 2012.Then, we investigated their sleep quality using the Pittsburgh sleep quality index ( PSQI) scale.Results Among the 92 IVF-ET patients, 19 patients ( 20.6%) at the first day during period , 43 patients (46.7%) on the day of oocyte retrieval , and 42 patients (45.6%) on the seventh day after embryo transfer got a score of PSQI over 7, which indicated that a number of patients who had experienced sleep disorders and the problem remained at a high level .At the first day during period , IVF-ET patients ’ score of PSQI in sleep quality, the time to fall asleep, sleep time, sleep efficiency, sleep disorders, daytime dysfunction, and the total score were (0.89 ±0.64), (0.96 ±0.75), (0.89 ±0.69), (0.46 ±0.76), (1.08 ±0.60), (1.05 ±0.72) scores, and (4.78 ±2.39), respectively, which were higher than the norm score of (0.63 ±0.68), (0.70 ±0.86), (0.70 ±0.58), (0.15 ±0.47), (0.90 ±0.44), (0.73 ±0.83), and (3.88 ±2.52) scores.The differences were significant (t=2.795 6, 2.274 8, 2.141 8, 3.412 9, 2.424 4, 2.922 3, 2.597 7, respectively;P<0.05).On the day of oocyte retrieval, IVF-ET patients’ score of PSQI in sleep quality, the time to fall asleep, sleep time, sleep efficiency, sleep disorders, daytime dysfunction, and the total score were (1.22 ±0.55), (1.23 ±0.79), (1.17 ±0.72), (0.91 ±0.93), (1.24 ±0.54), (1.38 ±0.72), and (7.23 ±2.07) scores, respectively.On the seventh day after embryo transfer , those scores were (1.08 ±0.58), (1.27 ±0.68), (1.18 ±0.77), (0.90 ±0.88), (1.27 ±0.54), (1.43 ± 0.76), and (7.09 ±1.87) scores, respectively.Compared with the first day during period , the differences of scores were significant (F=7.067, 4.879, 4.829, 8.427, 3.231, 7.232, 38.521, respectively;P<0.05). Conclusions The sleep quality of IVF-ET patients were significantly decreased , so measures should be taken to improve the sleep quality during different stages of treatment .

Objective: To observe the clinical therapeutic effect of Tang Shen Ning(TSN,a prescription of traditional Chinese medicine)for curing the early stage of diabetic nephropathy(DN).Methods: Adopting random and double-blind controlled trial methods,several indexes were observed in terms of uric micro-amount albumin excretion rate,creatinine clearance,hemorheology and platelet function et al.Results: TSN could significantly reduce urinary albumin,glomerulus's hyper-filtration,improve blood stream transform and inhibit platelet aggregation.Conclusion: TSN could protect renal functions during the early stage of DN.