1.Direct LDL Cholesterol Assay vs. Estimated Equations in Patients With Hypertriglyceridemia or Low LDL Cholesterol Levels
Jennifer RODRÍGUEZ-DOMÍNGUEZ ; Álvaro PIEDRA-AGUILERA ; María MARTÍNEZ-BUJIDOS ; Susana MALUMBRES-SERRANO ; Cristian MORALES-INDIANO ; Carla FERNÁNDEZ-PRENDES
Annals of Laboratory Medicine 2024;44(4):363-366
2.Access to and use of health information technology among obese and non-obese Americans: Analysis of the Health Information National Trends Survey data
Jacksaint Saintila ; Cristian Ramos-Vera ; Yaquelin E. Calizaya-Milla ; Veronica Ileana Hidalgo Villarreal ; Antonio Serpa-Barrientos ; Wilter C. Morales-Garcí ; a
Malaysian Journal of Nutrition 2023;29(No.2):255-266
Introduction: Health information technology (HIT) is essential in the prevention,
management, and treatment of obesity due to the medical data and information
available to health care providers and patients. However, exploration of HIT access
and use among obese individuals remains limited. Objective: The purpose of
this study was to compare access to and use of HIT among obese and non-obese
Americans. Methods: We considered cross-sectional secondary data from 3,865
United States adults that were collected through the Health Information National
Trends Survey in 2020. Contingency tables were performed stratifying between
men and women to assess whether they differed according to body mass index
(BMI) levels with respect to HIT categories. Results: Elevated BMI in women was
associated with the use of a computer, smartphone, or other electronic device to
e-mail or use the Internet to communicate with a doctor or a doctor’s office. In
addition, elevated BMI in both genders was associated with sharing information
from a smartphone/electronic device with a health professional. Finally, the use
of an electronic device to monitor or track health or activity was found to be more
prevalent among women with elevated BMI compared to those with normal BMI.
Conclusion: Future studies should expand research in terms of interventions
linked to health information technology in adults with obesity by considering the
gender factor. Moreover, the expansion of research into electronic health (eHealth)
interventions is particularly important because it would favour the prevention,
management, control, and treatment of obesity.
3.Test-Retest Reliability of Functional Magnetic Resonance Imaging Activation for a Vergence Eye Movement Task.
Cristian MORALES ; Suril GOHEL ; Xiaobo LI ; Mitchell SCHEIMAN ; Bharat B BISWAL ; Elio M SANTOS ; Chang YARAMOTHU ; Tara L ALVAREZ
Neuroscience Bulletin 2020;36(5):506-518
Vergence eye movements are the inward and outward rotation of the eyes responsible for binocular coordination. While studies have mapped and investigated the neural substrates of vergence, it is not well understood whether vergence eye movements evoke the blood oxygen level-dependent signal reliably in separate experimental visits. The test-retest reliability of stimulus-induced vergence eye movement tasks during a functional magnetic resonance imaging (fMRI) experiment is important for future randomized clinical trials (RCTs). In this study, we established region of interest (ROI) masks for the vergence neural circuit. Twenty-seven binocularly normal young adults participated in two functional imaging sessions measured on different days on the same 3T Siemens scanner. The fMRI experiments used a block design of sustained visual fixation and rest blocks interleaved between task blocks that stimulated eight or four vergence eye movements. The test-retest reliability of task-activation was assessed using the intraclass correlation coefficient (ICC), and that of spatial extent was assessed using the Dice coefficient. Functional activation during the vergence eye movement task of eight movements compared to rest was repeatable within the primary visual cortex (ICC = 0.8), parietal eye fields (ICC = 0.6), supplementary eye field (ICC = 0.5), frontal eye fields (ICC = 0.5), and oculomotor vermis (ICC = 0.6). The results demonstrate significant test-retest reliability in the ROIs of the vergence neural substrates for functional activation magnitude and spatial extent using the stimulus protocol of a task block stimulating eight vergence eye movements compared to sustained fixation. These ROIs can be used in future longitudinal RCTs to study patient populations with vergence dysfunctions.


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