1.Primary care of preputial adhesions in children – a retrospective cohort study
Suhasini Gazula ; Varunkumar Maddileti ; Praveena Dantala
Malaysian Family Physician 2022;17(1):52-56
		                        		
		                        			Introduction:
		                        			 Aside from religious circumcisions, the indications for circumcision are few. However, in the cultural context, many patients are unnecessarily referred for circumcision for physiological phimosis (adhesions). Due to parental concerns and misperceptions by general practitioners, nonretractile prepuce is one of the most common indications for referral to a paediatric surgeon in many countries. This study aimed to determine whether preputial adhesiolysis successfully managed symptomatic non-retractile foreskin and therefore prevented the need for circumcision.
		                        		
		                        			Methods:
		                        			 A retrospective review was performed of the health records of children who presented with preputial adhesion. We included 65 symptomatic patients (ballooning of the prepuce in all cases and additional dysuria in three cases) who underwent preputial adhesiolysis. All cases were followed up for 2 years. Circumcision was subsequently carried out for patients who developed fibrous scarring resulting in difficult retraction due to the development of thick adhesions or skin fissuring with persistence of symptoms.
		                        		
		                        			Results:
		                        			 Of the 65 boys, 58 (89.2%) achieved complete retraction of the prepuce. The remaining 7 boys (10.8%) presented with recurring symptoms and thick fibrosed prepuce, and they underwent circumcision due to the dense adhesions. Histopathological examination of the circumcised prepuces revealed balanitis xerotica obliterans in two cases.
		                        		
		                        			Conclusion
		                        			 Preputial adhesiolysis is a safe and effective treatment for symptomatic preputial adhesions in boys younger than 5 years old. The procedure avoids circumcision and its associated risks. Preputial adhesiolysis should be offered as a primary treatment instead of circumcision.
		                        		
		                        		
		                        		
		                        			Phimosis
		                        			;
		                        		
		                        			 Circumcision, Male
		                        			;
		                        		
		                        			 Balanitis Xerotica Obliterans
		                        			
		                        		
		                        	
2.Simplifying the ShangRing technique for circumcision in boys and men: use of the no-flip technique with randomization to removal at 7 days versus spontaneous detachment.
Mark A BARONE ; Philip S LI ; Richard K LEE ; Daniel OUMA ; Millicent OUNDO ; Mukhaye BARASA ; Jairus OKETCH ; Patrick OTIENDE ; Nixon NYANGWESO ; Mary MAINA ; Nicholas KISWI ; Betty CHIRCHIR ; Marc GOLDSTEIN ; Quentin D AWORI
Asian Journal of Andrology 2019;21(4):324-331
		                        		
		                        			
		                        			To assess safety of the no-flip ShangRing male circumcision technique and to determine clinical course and safety of spontaneous detachment (i.e., allowing the device to fall off), we conducted a case series of no-flip ShangRing circumcision combined with a randomized controlled trial of removal 7 days postcircumcision versus spontaneous detachment at two health facilities in Kenya. The primary outcome was the safety of the no-flip technique based on moderate and severe adverse events (AEs) during the procedure and through 42-day follow-up. A main secondary outcome was clinical course and safety of spontaneous detachment. Two hundred and thirty males 10 years and older underwent no-flip circumcision; 114 randomized to 7-day removal and 116 to spontaneous detachment. All circumcisions were successfully completed. Overall 5.3% (6/114) of participants in the 7-day group and 1.7% (2/116) in the spontaneous group had an AE; with no differences when compared to the 3% AE rate in historical data from African studies using the original flip technique (P = 0.07 and P = 0.79, respectively). Overall 72.4% (84/116) of participants in the spontaneous group wore the ShangRing until it detached. Among the remaining (27.6%; 32/116), the ring was removed, primarily at the participants' request, due to pain or discomfort. There was no difference in AE rates (P = 0.169), visit day declared healed (P = 0.324), or satisfaction (P = 0.371) between randomization groups. The median time to detachment was 14.0 (IQR: 7-21, range: 5-35) days. The no-flip technique and spontaneous detachment are safe, effective, and acceptable to boys and men 10 years and older. Phimosis and penile adhesions do not limit successful ShangRing circumcision with the no-flip technique.
		                        		
		                        		
		                        		
		                        			Adolescent
		                        			;
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Child
		                        			;
		                        		
		                        			Circumcision, Male/methods*
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Kenya
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Patient Satisfaction
		                        			;
		                        		
		                        			Treatment Outcome
		                        			;
		                        		
		                        			Wound Healing
		                        			;
		                        		
		                        			Young Adult
		                        			
		                        		
		                        	
4.Surgical plane positioning with a disposable circumcision suture device for the treatment of phimosis and redundant prepuce.
You-Feng HAN ; He-Song JIANG ; Jiu-Lin WANG ; Wu CHONG ; Hai CHEN ; Zhi-Peng XU ; Yun CHEN
National Journal of Andrology 2018;24(5):404-408
ObjectiveTo investigate the clinical effects of circumcision by surgical plane positioning with a disposable circumcision suture device in the treatment of phimosis and redundant prepuce.
METHODSFrom September 2016 to June 2017, we treated 250 patients with phimosis or redundant prepuce, 127 by conventional circumcision (the control group) and the other 123 by surgical plane positioning with a disposable circumcision suture device (the observation group). We compared the operation time, intra-operative bleeding, preputial frenulum alignment, postoperative ecchymosis, and postoperative penile appearance between the two groups of patients.
RESULTSCompared with the controls, the patients in the observation group showed significantly longer operation time ([4.48 ± 1.18] vs [7.17 ± 1.42] min, P<0.05), lower rates of intra-operative frenulum bleeding (15.0% [19/127] vs 4.1% [5/123], P<0.05) and frenulum misalignment (26.8% [34/127] vs 0.8% [1/123], P<0.05), higher incidence of postoperative ecchymosis (41.7% [53/127] vs 21.1% [26/123], P<0.05), and higher satisfaction of the patients with the postoperative penile appearance (92.9% [18/127] vs 98.4% [121/123], P<0.05). However, no statistically significant difference was found between the control and observation groups in intra-operative non-frenulum bleeding (4.7% [6/127] vs 1.6% [2/123], P = 0.164).
CONCLUSIONSCircumcision by surgical plane positioning with a disposable circumcision suture device can effectively avoid preputial frenulum misalignment, reduce intra-operative bleeding, and improve postoperative penile appearance.
Circumcision, Male ; instrumentation ; Disposable Equipment ; Ecchymosis ; etiology ; Foreskin ; Humans ; Incidence ; Male ; Operative Time ; Penis ; abnormalities ; surgery ; Personal Satisfaction ; Phimosis ; surgery ; Postoperative Complications ; etiology ; Postoperative Period ; Suture Techniques ; instrumentation
5.Circumcision reduces the incidence of human papillomavirus infection in men.
Liang-Liang HUANG ; Jun-Hong DENG ; Hua SHI ; Bin OU-YANG ; Jian-Ming LIU ; Zi-Bin LIN ; Jing-Xuan XIE ; Yan-Ni WEI ; Xiao-Hui HUANG
National Journal of Andrology 2018;24(4):327-330
ObjectiveTo investigate the association of circumcision with the incidence of human papillomavirus (HPV) infection in men.
METHODSWe collected the samples from the surface of the coronal sulcus, glans penis, penile shaft and scrotum of 351 males examined for HPV infection in our hospital from January 2016 to August 2017, of whom 118 had received circumcision while the other 233 had not. We compared the incidence rate of HPV infection between the circumcision and non-circumcision groups and analyzed the association of the age of circumcision with the incidence of HPV infection.
RESULTSHPV infection was found in 135 (38.46%) of the males, 29 (24.58%) in the circumcision group and 106 (45.49%) in the non-circumcision group, significantly lower in the former than in the latter (χ² = 14.48, P < 0.01). The incidence rate of HPV infection was also remarkably lower in the males circumcised at ≤17 years (13.16% [5/38]) than in those circumcised at >17 years of age (30.0% [24/80]) (χ² = 3.942, P = 0.047).
CONCLUSIONSMale circumcision helps reduce the incidence rate of HPV infection in men and earlier surgery may achieve even better effect.
Circumcision, Male ; statistics & numerical data ; Humans ; Incidence ; Male ; Papillomaviridae ; isolation & purification ; Papillomavirus Infections ; diagnosis ; epidemiology ; prevention & control ; Penis ; virology ; Scrotum ; virology
6.Frenulum identification positioning with a disposable suture device in circumcision to prevent postoperative penile frenulum malposition.
Yun-Quan HUANG ; Jing ZHENG ; Xu-Xiao ZHOU ; Zhe-Min YAO ; Ting ZHANG ; Qu-Fei SHAO ; Zhi-Gang WU
National Journal of Andrology 2017;23(5):422-426
		                        		
		                        			Objective:
		                        			To investigate the effect of the frenulum identification positioning method with a disposable suture device in circumcision for the prevention of postoperative penile frenulum malposition.
		                        		
		                        			METHODS:
		                        			Totally 212 patients with phimosis or redundant prepuce underwent circumcision from March 2015 to September 2016, including 109 cases of conventional circumcision (the control group) and 103 cases treated by frenulum identification positioning with a disposable suture device (the observation group). We observed the postoperative position of the penile frenulum and median raphe and compared the deviation angles of the frenulum between the two groups of patients.
		                        		
		                        			RESULTS:
		                        			The median of penile frenulum deviation angle (interquartile range) was 0 (3.56) in the observation group, significantly smaller than 12.41 (19.59) in the control (P <0.001, P = 0.000). And the rate of frenulum deviation was remarkably lower in the former (8.74% [9/103]) than in the latter group (66.06% [72/109]) (P <0.01).
		                        		
		                        			CONCLUSIONS
		                        			Circumcision using the frenulum identification positioning method with a disposable suture device can effectively avoid postoperative penile frenulum malposition. With the advantages of safety and easy operation, it deserves clinical application and popularization.
		                        		
		                        		
		                        		
		                        			Circumcision, Male
		                        			;
		                        		
		                        			instrumentation
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Disposable Equipment
		                        			;
		                        		
		                        			Foreskin
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Penis
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Phimosis
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Postoperative Complications
		                        			;
		                        		
		                        			prevention & control
		                        			;
		                        		
		                        			Suture Techniques
		                        			;
		                        		
		                        			instrumentation
		                        			;
		                        		
		                        			Sutures
		                        			
		                        		
		                        	
7.Human papillomavirus infection and male reproductive health.
National Journal of Andrology 2017;23(4):376-380
		                        		
		                        			
		                        			Human papillomavirus (HPV) infection is one of the worldwide sexually transmitted diseases (STD), and the DNA of HPV can exist in the normal epithelium of reproductive organs of both men and women. Because the majority of HPV infections are asymptomatic, healthy HPV-carriers become the main source of the infection. Studies show that HPV infection in men is correlated with STD, infertility, tumor of reproductive organs, and infection in the sexual partners. Therefore, measures should be taken to reduce male HPV infection, including circumcision, fewer sexual partners, and condom use.
		                        		
		                        		
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Asymptomatic Infections
		                        			;
		                        		
		                        			Carrier State
		                        			;
		                        		
		                        			virology
		                        			;
		                        		
		                        			Circumcision, Male
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Infertility, Male
		                        			;
		                        		
		                        			virology
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Papillomaviridae
		                        			;
		                        		
		                        			Papillomavirus Infections
		                        			;
		                        		
		                        			complications
		                        			;
		                        		
		                        			prevention & control
		                        			;
		                        		
		                        			transmission
		                        			;
		                        		
		                        			Reproductive Health
		                        			;
		                        		
		                        			Risk Factors
		                        			;
		                        		
		                        			Sexual Partners
		                        			;
		                        		
		                        			Sexually Transmitted Diseases
		                        			;
		                        		
		                        			virology
		                        			
		                        		
		                        	
8.Chinese parents' attitudes toward and their satisfaction with circumcision for 6-14 years old children.
Yi-Tian GUO ; Bin XU ; Ming CHEN
National Journal of Andrology 2017;23(4):319-322
		                        		
		                        			Objective:
		                        			To investigate the attitudes of the parents toward circumcision for 6-14 years old children and their satisfaction with the results.
		                        		
		                        			METHODS:
		                        			We performed circumcision in the Department of Urology of Zhongda Hospital for 220 children aged 6-14 years from 220 families between January 2010 and August 2016, including 70 cases of traditional and 150 cases of Shang Ring circumcision. We conducted telephone follow-ups among the parents of the patients concerning the decision-maker, reasons and regret for circumcision, acceptance of a second operation, source of information, satisfaction with surgical results, and reasons for dissatisfaction.
		                        		
		                        			RESULTS:
		                        			Most decisions for circumcision were made by the father, chiefly for health and hygiene. Their main sources of information on circumcision were Internet and friends. The parents of 29 patients were dissatisfied for long recovery or peri- and post-operative pain, including 19 cases (27.1%, 19/70) of traditional and 10 cases (6.7%, 10/150) of Shang Ring circumcision, with statistically significant differences between the two groups (P <0.05).
		                        		
		                        			CONCLUSIONS
		                        			Most parents were satisfied with circumcision, and the main reasons for dissatisfaction were long recovery and pain. The rate of satisfaction with Shang Ring circumcision was higher than that with traditional circumcision. Shang Ring circumcision is recommended for children aged 6-14 years old.
		                        		
		                        		
		                        		
		                        			Adolescent
		                        			;
		                        		
		                        			Asian Continental Ancestry Group
		                        			;
		                        		
		                        			Attitude
		                        			;
		                        		
		                        			Child
		                        			;
		                        		
		                        			China
		                        			;
		                        		
		                        			Circumcision, Male
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			psychology
		                        			;
		                        		
		                        			Convalescence
		                        			;
		                        		
		                        			psychology
		                        			;
		                        		
		                        			Fathers
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Pain, Postoperative
		                        			;
		                        		
		                        			psychology
		                        			;
		                        		
		                        			Parents
		                        			;
		                        		
		                        			psychology
		                        			;
		                        		
		                        			Personal Satisfaction
		                        			;
		                        		
		                        			Phimosis
		                        			;
		                        		
		                        			Time Factors
		                        			
		                        		
		                        	
9.A novel disposable ring versus the suture device in circumcision.
Yong-Jiu ZHAO ; Peng-Cheng ZHAN ; Qiang CHEN ; Wei CHENG ; Fu-Zeng YE ; Yi-Shui WANG ; Jun-Jun WANG ; Zhong-Mu TANG
National Journal of Andrology 2017;23(12):1093-1098
		                        		
		                        			Objective:
		                        			To investigate the clinical effect of a novel disposable ring versus that of the suture device in circumcision for redundant prepuce and phimosis.
		                        		
		                        			METHODS:
		                        			We randomly assigned 470 male patients with redundant prepuce or phimosis to receive circumcision with a novel disposable ring (the DR group, n = 235) or the suture device (the SD group, n = 235) and compared the operation time, intraoperative blood loss, pain scores, wound healing time, and postoperative complications and penile appearance between the two groups of patients.
		                        		
		                        			RESULTS:
		                        			All the operations were completed smoothly. Compared with the SD group, the DR group showed significantly shorter operation time ([7.49 ± 1.84] vs [3.83 ± 0.42] min, P <0. 05), less intraoperative blood loss ([3.34 ± 2.59] vs [2.41 ± 1.01] ml, P <0.05), lower intraoperative pain score (0.57 ± 0.76 vs 0.20 ± 0.47, P <0.05) and 6-hour postoperative pain score (3.42 ± 1.12 vs 0.48 ± 0.94, P <0.05), shorter wound healing time ([12.05 ± 2.80] vs [7.79 ± 1.65] d, P <0.05), lower incidence rates of postoperative glans congestion or edema (36.17% [85/235] vs 2.56% [6/235], P <0.05), dysuria or strenuous urination (34.04% [80/235] vs 2.13% [5/235], P <0.05) and bleeding or hematoma (5.11% [12/235] vs 1.28% [3/235], P <0.05), and higher satisfaction with postoperative penile appearance (90.6% [213/235] vs 95.8% [228/235], P <0.05). There were no statistically significant differences between the SD and DR groups in the pain scores at the sixth night after operation (1.31 ± 0.96 vs 1.34 ± 1.07, P >0.05) or while the staples scraping the underpants or at the ring removal (3.49 ± 1.22 vs 3.36 ± 1.41, P >0.05). No obvious postoperative infection or delayed healing was observed except for 3 cases of wound dehiscence (1 in the DR and 2 in the SD group) and 8 cases of delayed removal of the staples in the SD group.
		                        		
		                        			CONCLUSIONS
		                        			The novel disposable ring, with its advantages of short operation time, less bleeding and pain, good penile appearance, high safety, and simple operation, is obviously superior to the suture device in circumcision and deserves to be applied and popularized clinically. .
		                        		
		                        		
		                        		
		                        			Blood Loss, Surgical
		                        			;
		                        		
		                        			Circumcision, Male
		                        			;
		                        		
		                        			instrumentation
		                        			;
		                        		
		                        			Disposable Equipment
		                        			;
		                        		
		                        			Edema
		                        			;
		                        		
		                        			etiology
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Operative Time
		                        			;
		                        		
		                        			Pain Measurement
		                        			;
		                        		
		                        			Pain, Postoperative
		                        			;
		                        		
		                        			Penis
		                        			;
		                        		
		                        			abnormalities
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Personal Satisfaction
		                        			;
		                        		
		                        			Phimosis
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Postoperative Complications
		                        			;
		                        		
		                        			etiology
		                        			;
		                        		
		                        			Postoperative Period
		                        			;
		                        		
		                        			Suture Techniques
		                        			;
		                        		
		                        			instrumentation
		                        			;
		                        		
		                        			Sutures
		                        			;
		                        		
		                        			Wound Healing
		                        			
		                        		
		                        	
10.A novel disposable circumcision device versus conventional surgery in the treatment of redundant prepuce and phimosis.
Yong-Jiu ZHAO ; Peng-Cheng ZHAN ; Qiang CHEN ; Wei CHENG ; Fu-Zeng YE ; Yi-Shui WANG ; Jun-Jun WANG ; Jian-Hua LI ; Zhong-Mu TANG
National Journal of Andrology 2017;23(11):1007-1013
		                        		
		                        			Objective:
		                        			To compare the clinical effect of a novel disposable circumcision device Ring with that of conventional circumcision in the treatment of redundant prepuce and phimosis.
		                        		
		                        			METHODS:
		                        			Totally, 750 patients with redundant prepuce or phimosis underwent Ring circumcision (group A, n = 450) or conventional circumcision (group B, n = 300). We recorded the operation time, intraoperative blood loss, Visual Analogue Scale (VAS) intraoperative pain scores, postoperative complications, wound healing time, and patients' satisfaction with postoperative penile appearance, followed by comparison of the collected data between the two groups of patients.
		                        		
		                        			RESULTS:
		                        			All the operations were successfully completed. Group A, as compared with B, showed significantly shorter operation time ([3.78 ± 0.42] vs [26.24 ± 3.99] min, P <0.05), less intraoperative blood loss ([2.39 ± 1.01] vs [10.80 ± 3.57] ml, P <0.05), lower pain scores intraoperatively (0.14 ± 0.36 vs 2.30 ± 1.46, P <0.05), 6 hours postoperatively (0.32 ± 0.78 vs 3.03 ± 1.56, P <0.05) and at the ring removal (3.35 ± 1.42 vs 2.78 ± 1.43, P <0.05), shorter wound healing time ([7.61 ± 1.60] vs [8.57 ± 1.37] d, P <0.05), higher satisfaction with postoperative penile appearance (97.8% [440/450] vs 86% [258/300], P <0.05), and lower incidence of postoperative bleeding or hematoma (0.89% [4/450] vs 3% [9/300], P <0.05). No statistically significant differences were observed between groups A and B in the nocturnal pain score before the ring removal (1.45±1.02 vs 1.38 ± 0.92, P >0.05) or the postoperative incidence rate of edema (0.89% [4/450] vs 2.33% [7/300], P >0.05). There were no significant postoperative infections or delayed incision healing except for 1 case of wound dehiscence in each group.
		                        		
		                        			CONCLUSIONS
		                        			Ring circumcision, with its advantages of shorter operation time, less blood loss and pain, higher safety, and better postoperative penile appearance, is easily accepted by the patients and deserves wide clinical application.
		                        		
		                        		
		                        		
		                        			Blood Loss, Surgical
		                        			;
		                        		
		                        			statistics & numerical data
		                        			;
		                        		
		                        			Circumcision, Male
		                        			;
		                        		
		                        			instrumentation
		                        			;
		                        		
		                        			Disposable Equipment
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Incidence
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Operative Time
		                        			;
		                        		
		                        			Pain Measurement
		                        			;
		                        		
		                        			Patient Satisfaction
		                        			;
		                        		
		                        			Penis
		                        			;
		                        		
		                        			abnormalities
		                        			;
		                        		
		                        			anatomy & histology
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Phimosis
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Postoperative Complications
		                        			;
		                        		
		                        			Postoperative Hemorrhage
		                        			;
		                        		
		                        			Postoperative Period
		                        			;
		                        		
		                        			Wound Healing
		                        			
		                        		
		                        	
            

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