After radiotherapy for pelvic malignancies, pelvic insufficiency fracture (PIF), as a type of late injury event for pelvic bones, cannot be ignored, because it can exert a detrimental effect on patients' quality of life, and might make patients disabled and threaten their lives. Meanwhile, PIF is likely to be misdiagnosed with bone metastases. In this article, research progresses on potential pathogenesis, general characteristics, risk factors, diagnosis and treatment for PIF were reviewed.

Radiotherapy is an important treatment method for cervical cancer and endometrial cancer, and the therapeutic effect mainly depends on the precise tumor irradiation and the protection of normal tissues. Radiomics obtains comprehensive information features of tumors from medical images in a non-invasive and high-throughput manner. Establishing radiomics models according to these features helps to delineate the target volume and organs at risk of radiotherapy, and accurately predict the efficacy and toxicity of radiotherapy. Here, the basic process of establishing models using radiomics method and the progress in application of radiomics in radiotherapy for cervical cancer and endometrial cancer were reviewed.