1.Effectiveness of Autologous Fat Graft in Treating Fecal Incontinence
Hyeonseok JEONG ; Sung Hwan HWANG ; Hyoung Rae KIM ; Kil O RYU ; Jiyong LIM ; Hye Mi YU ; Jihoon YOON ; Chee Young KIM ; Kwang Yong JEONG ; Young Jae JUNG ; In Seob JEONG ; Young Gil CHOI
Annals of Coloproctology 2019;35(3):144-151
		                        		
		                        			
		                        			PURPOSE: The most common risk factor for fecal incontinence (FI) is obstetric injury. FI affects 1.4%–18% of adults. Most patients are unaware when they are young, when symptoms appear suddenly and worsen with aging. Autologous fat graft is widely used in cosmetic surgical field and may substitute for injectable bulky agents in treating FI. Authors have done fat graft for past several years. This article reports the effectiveness of the fat graft in treating FI and discusses satisfaction with the procedure. METHODS: Fat was harvested from both lateral thighs using 10-mL Luer-loc syringe. Pure fat was extracted from harvests and mixed with fat, oil, and tumescent through refinement. Fats were injected into upper border of posterior ano-rectal ring, submucosa of anal canal and intersphincteric space. Thirty-five patients with FI were treated with this method from July 2016 to February 2017 in Busan Hangun Hospital. They were 13 male (mean age, 60.8 years) and 22 female patients (mean age, 63.3 years). The Wexner score was checked before procedure. We evaluated outcome in outpatients by asking the patients. For 19 patients we checked the Wexner score after procedure. RESULTS: Symptom improved in 29 (82.9%), and not improved in 6 (17.1%). In 2 of 6 patients, they felt better than before procedure, although not satisfied. No improvement in 4. Mean Wexner score was 9.7 before procedure. There were no serious complications such as inflammation or fat embolism. CONCLUSION: Autologous fat graft can be an effective alternative treatment for FI. It is safe and easy to perform, and cost effective.
		                        		
		                        		
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Aging
		                        			;
		                        		
		                        			Anal Canal
		                        			;
		                        		
		                        			Busan
		                        			;
		                        		
		                        			Embolism, Fat
		                        			;
		                        		
		                        			Fats
		                        			;
		                        		
		                        			Fecal Incontinence
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Inflammation
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Methods
		                        			;
		                        		
		                        			Outpatients
		                        			;
		                        		
		                        			Risk Factors
		                        			;
		                        		
		                        			Syringes
		                        			;
		                        		
		                        			Thigh
		                        			;
		                        		
		                        			Transplants
		                        			
		                        		
		                        	
2.Training a Chest Compression of 6-7 cm Depth for High Quality Cardiopulmonary Resuscitation in Hospital Setting: A Randomised Controlled Trial.
Jaehoon OH ; Tae Ho LIM ; Youngsuk CHO ; Hyunggoo KANG ; Wonhee KIM ; Youngjoon CHEE ; Yeongtak SONG ; In Young KIM ; Juncheol LEE
Yonsei Medical Journal 2016;57(2):505-511
		                        		
		                        			
		                        			PURPOSE: During cardiopulmonary resuscitation (CPR), chest compression (CC) depth is influenced by the surface on which the patient is placed. We hypothesized that training healthcare providers to perform a CC depth of 6-7 cm (instead of 5-6 cm) on a manikin placed on a mattress during CPR in the hospital might improve their proper CC depth. MATERIALS AND METHODS: This prospective randomised controlled study involved 66 premedical students without CPR training. The control group was trained to use a CC depth of 5-6 cm (G 5-6), while the experimental group was taught to use a CC depth of 6-7 cm (G 6-7) with a manikin on the floor. All participants performed CCs for 2 min on a manikin that was placed on a bed 1 hour and then again 4 weeks after the training without a feedback. The parameters of CC quality (depth, rate, % of accurate depth) were assessed and compared between the 2 groups. RESULTS: Four students were excluded due to loss to follow-up and recording errors, and data of 62 were analysed. CC depth and % of accurate depth were significantly higher among students in the G 6-7 than G 5-6 both 1 hour and 4 weeks after the training (p<0.001), whereas CC rate was not different between two groups (p>0.05). CONCLUSION: Training healthcare providers to perform a CC depth of 6-7 cm could improve quality CC depth when performing CCs on patients who are placed on a mattress during CPR in a hospital setting.
		                        		
		                        		
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Beds
		                        			;
		                        		
		                        			Cardiopulmonary Resuscitation/*education/*methods
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Health Personnel/*education
		                        			;
		                        		
		                        			Hospitals
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			*Manikins
		                        			;
		                        		
		                        			Pressure
		                        			;
		                        		
		                        			Prospective Studies
		                        			;
		                        		
		                        			*Students, Medical
		                        			;
		                        		
		                        			Thorax/*physiology
		                        			
		                        		
		                        	
3.Abrupt formation of a right atrium thrombus detected by transesophageal echocardiography during laparoscopic assisted vaginal hysterectomy and spontaneous resolution during thromboembolectomy: A case report.
Kwangrae CHO ; Byung Kwan CHU ; Ilyong HAN ; Chee Mahn SHIN ; Young Jae KIM ; Soon Ho CHEONG ; Kun Moo LEE ; Se Hun LIM ; Jeong Han LEE ; Myoung Hun KIM ; Hyo Joong KIM
Korean Journal of Anesthesiology 2012;62(4):382-386
		                        		
		                        			
		                        			Intraoperative formation and management of a thrombus in right atrium has been reported occasionally. Nevertheless, it is rare that a right atrial thrombus with unstable hemodynamic changes detected by transesophageal echocardiography is resolved spontaneously. We report upon the 44-year-old woman, who had a right atrial thrombus detected by transesophageal echocardiography during laparoscopic assisted vaginal hysterectomy and resolved during thromboembolectomy.
		                        		
		                        		
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Echocardiography, Transesophageal
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Heart Atria
		                        			;
		                        		
		                        			Hemodynamics
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Hysterectomy, Vaginal
		                        			;
		                        		
		                        			Laparoscopy
		                        			;
		                        		
		                        			Thrombosis
		                        			
		                        		
		                        	
4.Comparison of dexmedetomidine and remifentanil for attenuation of hemodynamic responses to laryngoscopy and tracheal intubation.
Jeong Han LEE ; Hyojoong KIM ; Hyun Tae KIM ; Myoung Hun KIM ; Kwangrae CHO ; Se Hun LIM ; Kun Moo LEE ; Young Jae KIM ; Chee Mahn SHIN
Korean Journal of Anesthesiology 2012;63(2):124-129
		                        		
		                        			
		                        			BACKGROUND: This study was designed to compare the effect of dexmedetomidine and remifentanil used in anesthetic induction on hemodynamic change after direct laryngoscopy and tracheal intubation. METHODS: A total of 90 ASA class 1 or 2 patients were randomly assigned to one of 3 groups to receive one of the following treatments in a double-blind manner: normal saline (Group C, n = 30), dexmedetomidine 1 microg/kg (Group D, n = 30), remifentanil 1 microg/kg (Group R, n= 30). Anesthesia was induced with propofol 2 mg/kg and rocuronium 0.6 mg/kg and maintained with 2 vol% sevoflurane and 50% nitrous oxide in oxygen. In group D, dexmedetomidine 1 microg/kg was infused for 10 min before tracheal intubation. Patients in group R was received 1 microg/kg of remifentanil 1 minute before tracheal intubation. The systolic blood pressure, diastolic blood pressure and heart rate were recorded from entrance to operation room to 5 min after tracheal intubation. RESULTS: The percent increase in systolic and diastolic blood pressure due to tracheal intubation in group D and R were significantly lower than that of group C (P < 0.05). The heart rate 1 min after tracheal intubation was lower in groups R and D than in the group C (P < 0.05). CONCLUSIONS: In healthy normotensive patients, the use of dexmedetomidine during anesthetic induction suppressed a decrease in blood pressure due to anesthetic induction and blunted the hemodynamic responses to endotracheal intubation.
		                        		
		                        		
		                        		
		                        			Androstanols
		                        			;
		                        		
		                        			Anesthesia
		                        			;
		                        		
		                        			Blood Pressure
		                        			;
		                        		
		                        			Dexmedetomidine
		                        			;
		                        		
		                        			Heart Rate
		                        			;
		                        		
		                        			Hemodynamics
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Intubation
		                        			;
		                        		
		                        			Intubation, Intratracheal
		                        			;
		                        		
		                        			Laryngoscopy
		                        			;
		                        		
		                        			Methyl Ethers
		                        			;
		                        		
		                        			Nitrous Oxide
		                        			;
		                        		
		                        			Oxygen
		                        			;
		                        		
		                        			Piperidines
		                        			;
		                        		
		                        			Propofol
		                        			
		                        		
		                        	
5.Epidural anesthetic management of achondroplastic parturient dwarf undergoing cesarean section: A case report.
Se Hun LIM ; Chee Mahn SHIN ; Young Jae KIM ; Kun Moo LEE ; Jeong Han LEE ; Kwang Rae CHO ; Myoung Hun KIM ; Shin Hae CHANG
Anesthesia and Pain Medicine 2012;7(2):181-184
		                        		
		                        			
		                        			Achondroplasia is the most common non-lethal skeletal dysplasia. Underdevelopment and premature ossification of bones result in characteristic craniofacial and spinal abnormalities. Achondroplastic dwarfs have low fertility rates and require delivery by cesarean section due to their cephalo-pelvic disproportion. Controversy exists regarding the ideal anesthesia for an achondroplastic parturient dwarf for urgent cesarean section. Anesthesia, whether general or regional, presents many potential problems during cesarean section. We report the experience of the epidural anesthesia in an achondroplastic dwarf undergoing elective cesarean section.
		                        		
		                        		
		                        		
		                        			Achondroplasia
		                        			;
		                        		
		                        			Anesthesia
		                        			;
		                        		
		                        			Anesthesia, Epidural
		                        			;
		                        		
		                        			Birth Rate
		                        			;
		                        		
		                        			Cesarean Section
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Pregnancy
		                        			
		                        		
		                        	
6.Analgesic effect of preoperative versus intraoperative dexamethasone after laparoscopic cholecystectomy with multimodal analgesia.
Se Hun LIM ; Eun Ho JANG ; Myoung Hun KIM ; Kwangrae CHO ; Jeong Han LEE ; Kun Moo LEE ; Soon Ho CHEONG ; Young Jae KIM ; Chee Mahn SHIN
Korean Journal of Anesthesiology 2011;61(4):315-319
		                        		
		                        			
		                        			BACKGROUND: Pain after laparoscopy is multifactorial and different treatments have been proposed to provide pain relief. Multimodal analgesia is now recommended to prevent and treat post-laparoscopy pain. Dexamethasone is effective in reducing postoperative pain. The timing of steroid administration seems to be important. We evaluated the analgesic efficacy of preoperative intravenous dexamethasone 1 hour before versus during laparoscopic cholecystectomy with multimodal analgesia. METHODS: One hundred twenty patients aged 20 to 65 years old were allocated randomly into one of three groups (n = 40, in each). The patients in the group N received normal saline 1 hour before induction and after the resection of gall bladder. The patients in the group S1 received dexamethasone 8 mg 1 hour before induction and normal saline after the resection of gall bladder. The patients in the group S2 received normal saline 1 hour before induction and dexamethasone 8 mg after the resection of gall bladder. RESULTS: VAS scores of group S1 and S2 were lower than that of group N during 48 hours after laparoscopic cholecystectomy. There were no significant differences of VAS scores between the group S1 and the group S2. The analgesic consumption of group S1 and S2 were significantly lower than that of group N. CONCLUSIONS: A single dose of dexamethasone (8 mg) intravenously given 1 hour before induction or during operation was effective in reducing postoperative pain after laparoscopic cholecystectomy with multimodal analgesia. The analgesic efficacy of preoperative intravenous dexamethasone 1 hour before versus during surgery was not significantly different.
		                        		
		                        		
		                        		
		                        			Aged
		                        			;
		                        		
		                        			Analgesia
		                        			;
		                        		
		                        			Cholecystectomy, Laparoscopic
		                        			;
		                        		
		                        			Dexamethasone
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Laparoscopy
		                        			;
		                        		
		                        			Pain, Postoperative
		                        			;
		                        		
		                        			Urinary Bladder
		                        			
		                        		
		                        	
7.Comparison of the effects of acetaminophen to ketorolac when added to lidocaine for intravenous regional anesthesia.
Myoung Jin KO ; Jeong Han LEE ; Soon Ho CHEONG ; Chee Mahn SHIN ; Young Jae KIM ; Young Kyun CHOE ; Kun Moo LEE ; Se Hun LIM ; Young Hwan KIM ; Kwang Rae CHO ; Sang Eun LEE
Korean Journal of Anesthesiology 2010;58(4):357-361
		                        		
		                        			
		                        			BACKGROUND: This study was done to evaluate the effect on pain relief when acetaminophen was added to lidocaine for intravenous regional anesthesia (IVRA). METHODS: Sixty patients undergoing hand or forearm surgery received IVRA were assigned to three groups: Group C received 0.5% lidocaine diluted with 0.9% normal saline to a total volume of 40 ml (n = 20), Group P received 0.5% lidocaine diluted with intravenous acetaminophen 300 mg to a total volume of 40 ml (n = 20) and Group K received 0.5% lidocaine diluted with 0.9% normal saline plus ketorolac 10 mg made up to a total volume of 40 ml (n = 20). Sensory block onset time, tourniquet pain onset time, which was defined as the time from tourniquet application to fentanyl administration for relieving tourniquet pain and amount of analgesic consumption during surgery were recorded. Following deflation of tourniquet sensory recovery time, postoperative pain and quantity of analgesic uses in post-anesthesia care unit were assessed. RESULTS: Sensory block onset time was shorter in Group P compared to Group C (P < 0.05). Tourniquet pain onset time was delayed in Group P when compared with group C (P < 0.05). Postoperative pain and analgesic consumption were reduced in Group P and Group K compared to Group C (P < 0.001). CONCLUSIONS: The addition of acetaminophen to lidocaine for IVRA shortens the onset time of sensory block and delays tourniquet pain onset time, but not with ketorolac. Both acetaminophen and ketorolac reduce postoperative pain and analgesic consumption.
		                        		
		                        		
		                        		
		                        			Acetaminophen
		                        			;
		                        		
		                        			Anesthesia, Conduction
		                        			;
		                        		
		                        			Fentanyl
		                        			;
		                        		
		                        			Forearm
		                        			;
		                        		
		                        			Hand
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Ketorolac
		                        			;
		                        		
		                        			Lidocaine
		                        			;
		                        		
		                        			Pain, Postoperative
		                        			;
		                        		
		                        			Tourniquets
		                        			
		                        		
		                        	
8.General anesthesia for a spinal muscular atrophy type I patientundergoing feeding gastrostomy: A case report.
Eun Ho JANG ; Kwang Rae CHO ; Hyun Tae KIM ; Se Hun LIM ; Jeong Han LEE ; Kun Moo LEE ; Soon Ho CHEONG ; Young Jae KIM ; Chee Mahn SHIN
Anesthesia and Pain Medicine 2010;5(4):329-332
		                        		
		                        			
		                        			Spinal muscular atrophy (SMA) in children leads to progressive muscle weakness, dysphagia, aspiration, and death. The most common and severe form of SMA is designated as type I, also known as Werdnig-Hoffman Disease or Floppy Baby syndrome. We anesthetized an 8 month-old female infant with SMA type I undergoing feeding gastrostomy. We planned to use inhalational anesthesia without muscle relaxants. Anesthesia and surgery were uneventful. We herein report a case of successful peri-operative anesthetic management for SMA type I infant with aspiration pneumonia.
		                        		
		                        		
		                        		
		                        			Anesthesia
		                        			;
		                        		
		                        			Anesthesia, General
		                        			;
		                        		
		                        			Child
		                        			;
		                        		
		                        			Deglutition Disorders
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Gastrostomy
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Infant
		                        			;
		                        		
		                        			Muscle Weakness
		                        			;
		                        		
		                        			Muscles
		                        			;
		                        		
		                        			Muscular Atrophy, Spinal
		                        			;
		                        		
		                        			Neuromuscular Diseases
		                        			;
		                        		
		                        			Pneumonia, Aspiration
		                        			;
		                        		
		                        			Spinal Muscular Atrophies of Childhood
		                        			
		                        		
		                        	
9.Effect of bronchodilator on bronchial mucus transport velocity during inhalational anesthesia.
Young Jae KIM ; Myoung Hun KIM ; Hyun Sik KIM ; Kwang Rae CHO ; Se Hun LIM ; Jeong Han LEE ; Kun Moo LEE ; Soon Ho CHEONG ; Chee Mahn SHIN
Anesthesia and Pain Medicine 2010;5(4):310-313
		                        		
		                        			
		                        			BACKGROUND: Volatile-based anesthesia resulted in a significantly reduced cilia beat frequency. This study was to evaluate the effect of bronchodilator on bronchial mucus transport (BMT) distance measured with a bronchoscope during Inhalational anesthesia. METHODS: Twenty-four adult patients undergoing elective orthopedic surgery under inhalation anesthesia using sevoflurane and nitrous oxide were included. Twenty minutes after tracheal intubation, they were manually inspired without nebulization of salbutamol (control group: n = 12) or with nebulization of salbutamol(salbutamol group: n = 12). And then a single drop of 0.02 ml methylene blue was applied to the posterior mucosal surface of the right main bronchus 5 cm away from the carina under the bronchoscope. The distance of dye movement was measured 5 min after its application. RESULTS: BMT distance and velocity of methylene blue during 5min were 6.2 +/- 3.1 mm and 1.2 +/- 0.6 mm/min in control group, and 23.3 +/- 16.6 mm and 4.7 +/- 3.3 mm/min in salbutamol group, respectively. BMT distance and velocity of methylene blue in salbutamol group were longer and faster than those in control group(P < 0.05). CONCLUSIONS: Salbutamol facilitates the transport of bronchial secretion under sevoflurane-based inhalational anesthesia in term of BMT velocity.
		                        		
		                        		
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Albuterol
		                        			;
		                        		
		                        			Anesthesia
		                        			;
		                        		
		                        			Anesthesia, Inhalation
		                        			;
		                        		
		                        			Bronchi
		                        			;
		                        		
		                        			Bronchoscopes
		                        			;
		                        		
		                        			Cilia
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Intubation
		                        			;
		                        		
		                        			Methyl Ethers
		                        			;
		                        		
		                        			Methylene Blue
		                        			;
		                        		
		                        			Mucus
		                        			;
		                        		
		                        			Nitrous Oxide
		                        			;
		                        		
		                        			Orthopedics
		                        			
		                        		
		                        	
10.Inter-arm arterial pressure difference caused by prone position in the thoracic outlet syndrome patient: A case report.
Seung Su KIM ; Soon Ho CHEONG ; Won Jin LEE ; Dong Hwa JUN ; Myoung Jin KO ; Kwang Rae CHO ; Sang Eun LEE ; Young Hwan KIM ; Se Hun LIM ; Jeong Han LEE ; Kun Moo LEE ; Young Kyun CHOE ; Young Jae KIM ; Chee Mahn SHIN
Korean Journal of Anesthesiology 2010;58(1):91-94
		                        		
		                        			
		                        			Thoracic outlet syndrome has neurologic symptoms caused by compression of brachial plexus, blood vessel symptoms are caused by compression of the artery or vein. The authors report a case of sudden decrease in blood pressure of the left arm after turning the patient from supine position to prone position. They confirmed that the patient had thoracic outlet syndrome after performing computed tomography.
		                        		
		                        		
		                        		
		                        			Arm
		                        			;
		                        		
		                        			Arterial Pressure
		                        			;
		                        		
		                        			Arteries
		                        			;
		                        		
		                        			Blood Pressure
		                        			;
		                        		
		                        			Blood Vessels
		                        			;
		                        		
		                        			Brachial Plexus
		                        			;
		                        		
		                        			Glycosaminoglycans
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Neurologic Manifestations
		                        			;
		                        		
		                        			Prone Position
		                        			;
		                        		
		                        			Supine Position
		                        			;
		                        		
		                        			Thoracic Outlet Syndrome
		                        			;
		                        		
		                        			Veins
		                        			
		                        		
		                        	
            
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