1.Associations Between Multiple Falls and Mental Health Indices in Korean Older Adults: A Cross-sectional Study
Chaelyn LIM ; Hyun-Jin SON ; Byung-Gwon KIM ; Byeng-Chul YU ; Jiwon KIM ; Young-Seoub HONG
Journal of Preventive Medicine and Public Health 2025;58(3):269-277
Objectives:
This study was performed to investigate the prevalence of falls, mental health issues, and health behaviors among older adults, as well as to analyze the association between multiple falls and mental health status in this population.
Methods:
We utilized data from the 2017, 2019, and 2021 Korean Community Health Survey, a nationwide survey organized by region and conducted by the Korea Disease Control and Prevention Agency. Participants were categorized into no-fall, single-fall, and multiple fall groups based on responses to an index question regarding fall experiences and the number of such incidents reported in the survey. The chi-square test was applied to understand the characteristics of the elderly population in the community. Subsequently, multinomial logistic regression analysis was conducted to clarify the association between falls and mental health.
Results:
Integrated data analysis revealed that 11.3% of participants experienced a single fall, while 5.7% reported multiple falls. Participants from low-education and low-income backgrounds exhibited relatively high rates of falls. Additionally, non-drinkers and non-smokers reported falls more frequently than their counterparts who consumed alcohol and smoked. Multinomial logistic regression revealed significant associations between multiple falls and mental health factors. In particular, the severity of depression was directly proportional to the likelihood of experiencing multiple falls, with an odds ratio of 2.95 (95% confidence interval, 2.49 to 3.50).
Conclusions
We identified associations between various mental health-related factors—including sleep duration, subjective stress, the presence of depression, and Patient Health Questionnaire-9 score—and the occurrence of multiple falls.
2.Associations Between Multiple Falls and Mental Health Indices in Korean Older Adults: A Cross-sectional Study
Chaelyn LIM ; Hyun-Jin SON ; Byung-Gwon KIM ; Byeng-Chul YU ; Jiwon KIM ; Young-Seoub HONG
Journal of Preventive Medicine and Public Health 2025;58(3):269-277
Objectives:
This study was performed to investigate the prevalence of falls, mental health issues, and health behaviors among older adults, as well as to analyze the association between multiple falls and mental health status in this population.
Methods:
We utilized data from the 2017, 2019, and 2021 Korean Community Health Survey, a nationwide survey organized by region and conducted by the Korea Disease Control and Prevention Agency. Participants were categorized into no-fall, single-fall, and multiple fall groups based on responses to an index question regarding fall experiences and the number of such incidents reported in the survey. The chi-square test was applied to understand the characteristics of the elderly population in the community. Subsequently, multinomial logistic regression analysis was conducted to clarify the association between falls and mental health.
Results:
Integrated data analysis revealed that 11.3% of participants experienced a single fall, while 5.7% reported multiple falls. Participants from low-education and low-income backgrounds exhibited relatively high rates of falls. Additionally, non-drinkers and non-smokers reported falls more frequently than their counterparts who consumed alcohol and smoked. Multinomial logistic regression revealed significant associations between multiple falls and mental health factors. In particular, the severity of depression was directly proportional to the likelihood of experiencing multiple falls, with an odds ratio of 2.95 (95% confidence interval, 2.49 to 3.50).
Conclusions
We identified associations between various mental health-related factors—including sleep duration, subjective stress, the presence of depression, and Patient Health Questionnaire-9 score—and the occurrence of multiple falls.
3.Associations Between Multiple Falls and Mental Health Indices in Korean Older Adults: A Cross-sectional Study
Chaelyn LIM ; Hyun-Jin SON ; Byung-Gwon KIM ; Byeng-Chul YU ; Jiwon KIM ; Young-Seoub HONG
Journal of Preventive Medicine and Public Health 2025;58(3):269-277
Objectives:
This study was performed to investigate the prevalence of falls, mental health issues, and health behaviors among older adults, as well as to analyze the association between multiple falls and mental health status in this population.
Methods:
We utilized data from the 2017, 2019, and 2021 Korean Community Health Survey, a nationwide survey organized by region and conducted by the Korea Disease Control and Prevention Agency. Participants were categorized into no-fall, single-fall, and multiple fall groups based on responses to an index question regarding fall experiences and the number of such incidents reported in the survey. The chi-square test was applied to understand the characteristics of the elderly population in the community. Subsequently, multinomial logistic regression analysis was conducted to clarify the association between falls and mental health.
Results:
Integrated data analysis revealed that 11.3% of participants experienced a single fall, while 5.7% reported multiple falls. Participants from low-education and low-income backgrounds exhibited relatively high rates of falls. Additionally, non-drinkers and non-smokers reported falls more frequently than their counterparts who consumed alcohol and smoked. Multinomial logistic regression revealed significant associations between multiple falls and mental health factors. In particular, the severity of depression was directly proportional to the likelihood of experiencing multiple falls, with an odds ratio of 2.95 (95% confidence interval, 2.49 to 3.50).
Conclusions
We identified associations between various mental health-related factors—including sleep duration, subjective stress, the presence of depression, and Patient Health Questionnaire-9 score—and the occurrence of multiple falls.
4.Erratum: Korean translation and validation of the Workplace Positive emotion, Engagement, Relationships, Meaning, and Accomplishment (PERMA)-Profiler
Seong Pil CHOI ; Chunhui SUH ; Jae Won YANG ; Byung Jin YE ; Chae Kwan LEE ; Byung Chul SON ; Maro CHOI
Annals of Occupational and Environmental Medicine 2024;36(1):e26-
5.Clinical Characteristics of Sciatica in Patients with Piriformis Syndrome Improved by Decompression Surgery
Dong-kwan LEE ; Byung-chul SON
The Nerve 2024;10(1):25-30
Objective:
To clearly identify the symptoms of sciatica in patients with piriformis syndrome, we retrospectively reviewed patients whose symptoms significantly improved over long-term postoperative follow-up.
Methods:
Among patients who underwent sciatic nerve decompression for piriformis syndrome over the past 3 years, the preoperative sciatic pain symptoms of 32 patients whose symptoms were confirmed to have improved by more than 50% during more than 1 year of follow-up were analyzed. To identify the characteristics of sciatic pain in piriformis syndrome, we investigated pain when sitting, pain when resting, pain when standing or walking, and pain when resting at night. In addition, the distribution of sciatic pain in the lower back, buttocks, lower extremities, and feet was investigated.
Results:
The most common symptom was pain when sitting, which was present in 25 patients (81%). Pain characteristically occurred even at rest, occurring in 62.5% of patients while lying down at night and in 53.1% of patients during daytime rest. Sciatic pain from piriformis syndrome was most commonly distributed in the buttock (90.6%) and also present in the lower back (37.5%). Pain was present in the posterior thigh in 23 patients (71.9%), in the calf in 68.8% of patients, and in the foot in 50% of patients.
Conclusion
Buttock pain exacerbated by sitting was the most common pattern of pain in patients with piriformis syndrome. However, the sciatic pain of this disease was also found to be characterized by pain that persisted even at rest.
6.Extent of Pain Distribution in Entrapment of the Greater Occipital Nerve Identified Through Skin Lesions of Herpes Zoster Involving the Greater Occipital Nerve
The Nerve 2024;10(2):126-133
Herpes zoster (HZ) involving the upper cervical nerves (C2-C4), which innervate the posterior head, is rare. There have also been few reports of HZ lesions involving the greater occipital nerve (GON), which refers to the medial branch of the dorsal ramus of the second cervical nerve. Pain due to GON entrapment radiates not only to the temporo-occipital region, but also to the ear, retro-auricular and sub-auricular areas of the neck, the angle of the jaw, and the posterolateral neck. Herein, we present the case of a patient who underwent decompression surgery for referred trigeminal pain due to GON entrapment and who developed HZ one week later. Skin lesions of HZ involving the GON occurred not only in the occipital area but also in the ipsilateral ear, auricle, posterior and anterolateral neck. This case of HZ involved all cutaneous areas innervated by the C2, C3, and C4 spinal nerves. The extent of the skin lesions indicated where the pain from the GON radiated.
7.Intraneural and Extraneural Ganglion Cysts at the Greater Sciatic Notch Involving the Sciatic Nerve Causing Sciatica: Two Case Reports
The Nerve 2024;10(2):113-125
Intraneural ganglion cysts (IGCs) are benign mucinous cysts within the epineurium of peripheral nerves. Hip joint-related IGCs are much rarer than those that arise from peripheral nerves around the joints of limbs. The unifying articular synovial theory has been accepted as explaining the pathogenesis of IGCs. Herein, we present two cases of hip joint-related ganglion cysts—one case of an IGC and one case of an extraneural ganglion cyst—that involved the sciatic nerve through the articular branch of the hip joint and caused sciatica. Preoperative and postoperative magnetic resonance imaging (MRI) findings of the articular branch derived from a paralabral cyst of the hip are presented, as well as photographic findings of a ganglion cyst with the articular branch addressed through a transgluteal approach. Despite improvement in postoperative sciatica due to cyst decompression and treatment aimed at addressing the articular branch, the articular branch remained present on postoperative MRI. Unlike IGCs arising from peripheral nerves associated with limb joints, involvement of the sciatic nerve might make it challenging to treat articular branches due to the location of the sciatic nerve over the greater sciatic notch of the deep gluteal region.
8.Erratum: Korean translation and validation of the Workplace Positive emotion, Engagement, Relationships, Meaning, and Accomplishment (PERMA)-Profiler
Seong Pil CHOI ; Chunhui SUH ; Jae Won YANG ; Byung Jin YE ; Chae Kwan LEE ; Byung Chul SON ; Maro CHOI
Annals of Occupational and Environmental Medicine 2024;36(1):e26-
9.Erratum: Korean translation and validation of the Workplace Positive emotion, Engagement, Relationships, Meaning, and Accomplishment (PERMA)-Profiler
Seong Pil CHOI ; Chunhui SUH ; Jae Won YANG ; Byung Jin YE ; Chae Kwan LEE ; Byung Chul SON ; Maro CHOI
Annals of Occupational and Environmental Medicine 2024;36(1):e26-
10.Clinical Validation of the Unparalleled Sensitivity of the Novel Allele-Discriminating Priming System Technology–Based EGFR Mutation Assay in Patients with Operable Non–Small Cell Lung Cancer
Il-Hyun PARK ; Dae-Soon SON ; Yoon-La CHOI ; Ji-Hyeon CHOI ; Ji-Eun PARK ; Yeong Jeong JEON ; Minseob CHO ; Hong Kwan KIM ; Yong Soo CHOI ; Young Mog SHIM ; Jung Hee KANG ; Suzy PARK ; Jinseon LEE ; Sung-Hyun KIM ; Byung-Chul LEE ; Jhingook KIM
Cancer Research and Treatment 2024;56(1):81-91
Purpose:
Recently, we developed allele-discriminating priming system (ADPS) technology. This method increases the sensitivity of conventional quantitative polymerase chain reaction up to 100 folds, with limit of detection, 0.01%, with reinforced specificity. This prospective study aimed to develop and validate the accuracy of ADPS epidermal growth factor receptor (EGFR) Mutation Test Kit using clinical specimens.
Materials and Methods:
In total 189 formalin-fixed paraffin-embedded tumor tissues resected from patients with non–small cell lung cancer were used to perform a comparative evaluation of the ADPS EGFR Mutation Test Kit versus the cobas EGFR Mutation Test v2, which is the current gold standard. When the two methods had inconsistent results, next-generation sequencing–based CancerSCAN was utilized as a referee.
Results:
The overall agreement of the two methods was 97.4% (93.9%-99.1%); the positive percent agreement, 95.0% (88.7%-98.4%); and the negative percent agreement, 100.0% (95.9%-100.0%). EGFR mutations were detected at a frequency of 50.3% using the ADPS EGFR Mutation Test Kit and 52.9% using the cobas EGFR Mutation Test v2. There were 10 discrepant mutation calls between the two methods. CancerSCAN reproduced eight ADPS results. In two cases, mutant allele fraction was ultra-low at 0.02% and 0.06%, which are significantly below the limit of detection of the cobas assay and CancerSCAN. Based on the EGFR genotyping by ADPS, the treatment options could be switched in five patients.
Conclusion
The highly sensitive and specific ADPS EGFR Mutation Test Kit would be useful in detecting the patients who have lung cancer with EGFR mutation, and can benefit from the EGFR targeted therapy.

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