1.The Change of Metabolic Syndrome Prevalence and Its Risk Factors in Korean Adults for Decade: Korea National Health and Nutrition Examination Survey for 2008–2017
Min-hyun KIM ; Sang-hee LEE ; Kyung-Suk SHIN ; Doo-Yong SON ; Sun-Hee KIM ; Hyun JOE ; Byung-Wook YOO ; Sung-Ho HONG ; Choo-Yon CHO ; Hwang-Sik SHIN ; Yong-Jin CHO ; Jung-Eun OH
Korean Journal of Family Practice 2020;10(1):44-52
		                        		
		                        			 Background:
		                        			Metabolic syndrome is a nationwide health problem, which is associated with the development of cardiovascular diseases, diabetes, and chronic renal failure. The prevalence of metabolic syndrome in Korea significantly increased from 1998 to 2007. After that, the prevalence was stable in female but still increasing in male. The objective of this study was to evaluate how the prevalence and risk factors for metabolic syndrome changed in Korean adults through the last decade. 
		                        		
		                        			Methods:
		                        			Data from the Korea National Health and Nutrition Examination Survey 2008 to 2017 was used. National Cholesterol Education Program Adult Treatment Panel III were used to define metabolic syndrome. We compared how each metabolic syndrome component and the risk factors changed through the years. 
		                        		
		                        			Results:
		                        			A total of 51,177 (30,092 female and 21,085 male) people were included in this study. The prevalence of metabolic syndrome in male increased from 24.5% in 2008 to 28.1% in 2017, whereas that in female was stable at 20.5% in 2008 from 18.7% in 2017. Waist circumference measurements and fasting glucose levels increased through the decade in male, whereas only fasting glucose levels increased in female. 
		                        		
		                        			Conclusion
		                        			Since the last decade, the prevalence of metabolic syndrome in Korean adults has increased in male but remained stable in female. Lifestyle intervention in male, namely ceasing smoking and drinking could prevent increasing metabolic syndrome prevalence in Korean adults. 
		                        		
		                        		
		                        		
		                        	
2.The Relation of High-Sensitivity C-Reactive Protein with Hyperuricemia: Using Health Examination Data at One Medical Institution’s Health Examination Center (2016–2017)
Da-bin KIM ; Jung-Eun OH ; Hyun-seo PARK ; Hwang-Sik SHIN ; Yong-Jin CHO ; Sun-hee KIM ; Hyun JOE ; Byung-Wook YOO ; Sung-Ho HONG ; Choo-Yon CHO ; Doo-Yong SON ; Kyung-Suk SHIN
Korean Journal of Family Practice 2020;10(1):39-43
		                        		
		                        			 Background:
		                        			Several studies have shown that elevated serum uric acid levels are associated with cardiovascular disease. High sensitivity C-reactive protein (hs-CRP) has been shown to be a measure of the severity and prognosis of cardiovascular disease. The aim of this study was to investigate the association of hs-CRP with hyperuricemia. 
		                        		
		                        			Methods:
		                        			From March 2016 to November 2017, a total of 26,987 patients who received a health check-up at a Soonchunhyang University Cheonan Hospital, Korea, were enrolled. Foreigners, patients who had hs-CRP score greater than 10 or white blood cell score greater than 10,000, those who did not respond sincerely, those who had previously been diagnosed with gout and cerebrovascular disease, and females were excluded. Data were collected from 2,808 patients. 
		                        		
		                        			Results:
		                        			The subjects were divided into four sections by 25th percentile, 50th percentile, 75th percentile, and 100th percentile based on the distribution of hs-CRP. Serum hs-CRP levels were 1.85 (1.34–2.56), 2.59 (1.90–3.54), and 3.64 (2.70–4.93) respectively in the second, third, and fourth quartiles based on the first quartile. The odds ratios were 1.46 (1.05–2.03), 1.76 (1.27–2.45), and 2.27 (1.64–3.14) after adjusting the disturbance variables of age, body mass index, smoking status, and regular exercise. 
		                        		
		                        			Conclusion
		                        			In this study, we evaluated the relationship between serum hs-CRP and hyperuricemia, which are the risk factors for cardiovascular disease, and found statistically significant correlations. These results were still significant after adjusting for age, smoking, exercise, and body mass index. 
		                        		
		                        		
		                        		
		                        	
3.Association between Glycated Hemoglobin A1c and Intraocular Pressure in Nondiabetic Subjects
Kyung O KANG ; Seong Heub JUN ; Kyung Suk SHIN ; Doo Yong SON ; Byung Wook YOO ; Sun Hee KIM ; Hyun JOE ; Sung Ho HONG ; Choo Yon CHO ; Hwang Sik SHIN ; Yong Jin CHO ; Jung Eun OH
Korean Journal of Family Practice 2019;9(1):59-63
		                        		
		                        			
		                        			BACKGROUND: Diabetic patients are known to have unusually high mean intraocular pressure (IOP); attributable to autonomic dysfunction and genetic factors. A recent study reported that diabetic complications occur in not only diabetes but also prediabetes. We performed this study to analyze the relationship between glycated hemoglobin A1c (HbA1c) levels and IOP in non-diabetics using electronic medical records at the health screening center of Soon Chun Hyang University Seoul Hospital.METHODS: We considered 16,643 individuals who visited the health screening center of Soon Chun Hyang University Seoul Hospital between November 2015 and September 2017. In total, 3,029 subjects were included in the study. Exclusion criteria included a history of hypertension, diabetes, stroke, cardiovascular disease, hepatitis (A-C), cancer, other disease, fasting blood glucose of 126 mg/dL or higher, HbA1c of 6.5% or higher, and individuals whose binocular IOP could not be measured. We categorized subjects into two groups; those with HbA1c less than or equal to 5.6%, and those with HbA1c greater than 5.6% and less than 6.5%. The mean IOP of each group was compared by gender.RESULTS: After adjusting for factors affecting IOP, analysis of variance was performed to analyze the relationship between HbA1c and IOP. There was no statistically significant difference between the HbA1c groups in males. However, there was a significant difference in IOP between females in the the higher and lower HbA1c groups.CONCLUSION: There was a statistically significant relationship between mean IOP and HbA1c in females without diabetes. Further research is needed with prospective and extensive data collection.
		                        		
		                        		
		                        		
		                        			Blood Glucose
		                        			;
		                        		
		                        			Data Collection
		                        			;
		                        		
		                        			Diabetes Complications
		                        			;
		                        		
		                        			Diabetes Mellitus
		                        			;
		                        		
		                        			Electronic Health Records
		                        			;
		                        		
		                        			Fasting
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Health Promotion
		                        			;
		                        		
		                        			Hemoglobin A, Glycosylated
		                        			;
		                        		
		                        			Hepatitis
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Hypertension
		                        			;
		                        		
		                        			Intraocular Pressure
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Mass Screening
		                        			;
		                        		
		                        			Myocardial Infarction
		                        			;
		                        		
		                        			Prediabetic State
		                        			;
		                        		
		                        			Prospective Studies
		                        			;
		                        		
		                        			Seoul
		                        			;
		                        		
		                        			Telescopes
		                        			
		                        		
		                        	
4.The factors associated with Vitamin D deficiency in community dwelling elderly in Korea.
Sun Hea KIM ; Jung Eun OH ; Dong Won SONG ; Choo Yon CHO ; Sung Ho HONG ; Yong Jin CHO ; Byung Wook YOO ; Kyung Suk SHIN ; Hyun JOE ; Hwang Sik SHIN ; Doo Yong SON
Nutrition Research and Practice 2018;12(5):387-395
		                        		
		                        			
		                        			BACKGROUND/OBJECTIVES: Recent studies showed vitamin D deficiency is linked to chronic diseases in addition to skeletal metabolism which could threaten the elderly. We analyzed health conditions and socio-demographic factors associated with vitamin D deficiency in community dwelling people aged 65 years and older. SUBJECTS/METHOD: Data from the Korea National Health and Nutrition Examination Survey (KNHANES) 2010 to 2012 were obtained. A total of 2,687 subjects aged 65 years and older were participated. The cutoff value of the Vitamin D deficiency was considered as serum 25-hydroxyvitamin D [25(OH)D] ≤ 20 ng/mL (50 nmol/L). RESULTS: The overall prevalence rate of vitamin D deficiency in the elderly was 62.1%. The factors such as female, obesity, metabolic syndrome, current smoker, and skipping breakfast were positively associated with vitamin D deficiency, but high intensity of physical activity and more than 9 hours of sleep duration were negatively associated with vitamin D deficiency (all P < 0.05). CONCLUSIONS: It is important that health professions know that the factors proved in this study are connected to vitamin D deficiency thus provide information and intervention strategies of vitamin D deficiency to old aged people.
		                        		
		                        		
		                        		
		                        			Aged*
		                        			;
		                        		
		                        			Aging
		                        			;
		                        		
		                        			Breakfast
		                        			;
		                        		
		                        			Chronic Disease
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Health Occupations
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Independent Living*
		                        			;
		                        		
		                        			Korea*
		                        			;
		                        		
		                        			Metabolism
		                        			;
		                        		
		                        			Motor Activity
		                        			;
		                        		
		                        			Nutrition Surveys
		                        			;
		                        		
		                        			Obesity
		                        			;
		                        		
		                        			Prevalence
		                        			;
		                        		
		                        			Risk Factors
		                        			;
		                        		
		                        			Vitamin D Deficiency*
		                        			;
		                        		
		                        			Vitamin D*
		                        			;
		                        		
		                        			Vitamins*
		                        			
		                        		
		                        	
5.A Case of Molluscum Contagiosum Treated by Ingenol Mebutate (Picato®).
Korean Journal of Dermatology 2017;55(2):145-146
		                        		
		                        			
		                        			No abstract available.
		                        		
		                        		
		                        		
		                        			Molluscum Contagiosum*
		                        			
		                        		
		                        	
6.A Case of Dermatofibrosarcoma Protuberans Treated with Slow Mohs Micrographic Surgery.
Hyun Jae JOE ; Joon Beom LEE ; Byung Ho OH
Korean Journal of Dermatology 2017;55(4):266-267
		                        		
		                        			
		                        			No abstract available.
		                        		
		                        		
		                        		
		                        			Dermatofibrosarcoma*
		                        			;
		                        		
		                        			Mohs Surgery*
		                        			
		                        		
		                        	
7.A Case of Kerion Celsi Misdiagnosed as Ruptured Epidermal Cyst.
Joon Bum LEE ; Hyun Jae JOE ; Byung Ho OH
Korean Journal of Medical Mycology 2016;21(3):73-77
		                        		
		                        			
		                        			Kerion celsi is an inflammatory infection, caused by a vigorous T-cell mediated host response to the dermatophyte infection. In the case of severe inflammation, it can be misdiagnosed as other disease like cellulitis, impetigo, furuncle and epidermal cyst. Microsporum(M.) canis is most likely transmitted by contact of animal hosts such as cats and dogs with humans. We report the 75-year-old female who presented two months history of tender erythematous scaly plaques with pustules, crusts on right scalp area. At first, from the histopathologic findings of the lesion, the patient was diagnosed epidermal cyst because of cyst-like structure in mid-dermis. But the fungal culture revealed M. canis as the causative fungus. Herein we report a educational case of kerion celsi mistaken for ruptured epidermal cyst.
		                        		
		                        		
		                        		
		                        			Aged
		                        			;
		                        		
		                        			Animals
		                        			;
		                        		
		                        			Arthrodermataceae
		                        			;
		                        		
		                        			Cats
		                        			;
		                        		
		                        			Cellulitis
		                        			;
		                        		
		                        			Dogs
		                        			;
		                        		
		                        			Epidermal Cyst*
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Fungi
		                        			;
		                        		
		                        			Furunculosis
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Impetigo
		                        			;
		                        		
		                        			Inflammation
		                        			;
		                        		
		                        			Scalp
		                        			;
		                        		
		                        			T-Lymphocytes
		                        			;
		                        		
		                        			Tinea Capitis*
		                        			
		                        		
		                        	
8.Sweet Syndrome in a Child with Aplastic Anemia after Receiving Recombinant Granulocyte Colony-stimulating Factor.
Hyun Jae JOE ; Byung Ho OH ; Sung Ae KIM
Korean Journal of Dermatology 2016;54(4):308-309
		                        		
		                        			
		                        			No abstract available.
		                        		
		                        		
		                        		
		                        			Anemia, Aplastic*
		                        			;
		                        		
		                        			Child*
		                        			;
		                        		
		                        			Granulocyte Colony-Stimulating Factor*
		                        			;
		                        		
		                        			Granulocytes*
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Sweet Syndrome*
		                        			
		                        		
		                        	
9.Fatigue and Its Association with Socio-Demographic and Clinical Variables in a Working Population.
Soyoung PARK ; Sook Haeng JOE ; Seung Hyun KIM ; Chang Su HAN ; Byung Joo HAM ; Young Hoon KO
Korean Journal of Psychosomatic Medicine 2014;22(1):3-12
		                        		
		                        			
		                        			OBJECTIVES: We aimed to explore the relationship among fatigue and perceived stress, depressive mood in the working population. We also examined associations with demographic and life style factors and investigated the effect of individual coping skills on these associations. METHODS: Fatigue Severity Scale(FSS), Perceived Stress Scale(PSS), Brief Encounter Psychosocial Instrument - Korean version(BEPSI-K), Beck Depression Inventory(BDI), Stress Coping Skill Questionnaire were administered to 621 civil servants. All of above and other demographic factors are self-administered questionnaire survey and this study is cross sectional. RESULTS: Mean FSS score was 3.04 which was lower than 3.22, the severity cut off score. FSS, PSS, BEPSI-K, BDI were all higher in female. Subjects with active coping skills showed relatively low fatigue, perceived stress, depressive mood than those with passive coping skills. Logistic regression analyses indicated that the PSS, BDI, BEPSI-K in working population increase the risk of fatigue and regular exercise lowers the risk. CONCLUSIONS: Adults who were afflicted by stress, experienced depressive mood or were physically inactive were at much higher risk of feeling fatigue. Since no other large data sets are available for fatigue, the results from this study could serve a very useful purpose, to furnish a basis for comparison with future research results based on more complete data.
		                        		
		                        		
		                        		
		                        			Adaptation, Psychological
		                        			;
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Dataset
		                        			;
		                        		
		                        			Demography
		                        			;
		                        		
		                        			Depression
		                        			;
		                        		
		                        			Fatigue*
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Life Style
		                        			;
		                        		
		                        			Logistic Models
		                        			;
		                        		
		                        			Questionnaires
		                        			
		                        		
		                        	
10.The Stress Perception, Depressive Symptoms and Medical Comorbidity in Healthcare Center.
In Bo SHIM ; Sook Haeng JOE ; Byung Joo HAM ; Changsu HAN ; Hyun Ghang JEONG ; Young Hoon KO
Korean Journal of Psychosomatic Medicine 2013;21(1):27-43
		                        		
		                        			
		                        			OBJECTIVES: We surveyed this study for knowing the relation within stress, depression and medical comorbidities, and finding the risk factors of major depression. METHODS: 1764 subjects were enrolled from Jan. 2009 to Dec. 2009 who visit Korea University Guro hospital healthcare center. The subjects answered the questionnaire of PSS(Perceived Stress Scale), PHQ-9(Patient Health Questionnaire-9) and the demographic data. We categorized them as the stress group, depressive group, medical comorbidity group and analyzed the correlation analyses and logistic regression analyses. RESULTS: 198 of 1764 subjects(11.8%) were applied to major depression, and the depressive group showed the higher mean stress score(23.19) and mean depression score(12.95) than the normal group. The total PHQ-9 score was increased by perceiving more stress, having more medical comorbidities. The subjects with female, visiting due to recent health problems, irregular exercise, current smoking, history of angina and cerebrovascular disease showed the increased risk of major depression. CONCLUSIONS: In this study, we find the PSS, PHQ-9 were valuable for mental health screening in healthcare center. As perceiving more stress and having more medical comorbidity, risk of major depression were increased. Accordingly the individuals with medical diseases or unhealthy lifestyle would need the mental health screen.
		                        		
		                        		
		                        		
		                        			Comorbidity
		                        			;
		                        		
		                        			Delivery of Health Care
		                        			;
		                        		
		                        			Depression
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Korea
		                        			;
		                        		
		                        			Life Style
		                        			;
		                        		
		                        			Logistic Models
		                        			;
		                        		
		                        			Mass Screening
		                        			;
		                        		
		                        			Mental Health
		                        			;
		                        		
		                        			Questionnaires
		                        			;
		                        		
		                        			Risk Factors
		                        			;
		                        		
		                        			Smoke
		                        			;
		                        		
		                        			Smoking
		                        			
		                        		
		                        	
            
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