The maxillary lateral incisor is the second most common congenitally absent tooth. This is a case of a 25-year-old with  maxillary  lateral  incisors  agenesis,  multiple  maxillary  anterior  diastema.  Pre-adjusted  technique  was  used, gingivectomy and frenectomy to release tooth movement. Patient’s profile was straight, interdental relationship was  class  I,  enlarged  space  of  maxillary  lateral  incisors,  space  was  replaced  by  prostheses.  The  treatment  of maxillary lateral incisors agenesis responsible for orthodontic, periodontic and prosthodontic achieved a pleasant aesthetic and function.
		                        		
		                        		
		                        		
		                        			Diastema
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		                        			 Incisor