1.Research progress of lncRNA PVT1 in cardiovascular diseases
Shuang LIU ; Bofang ZHANG ; Jing CHEN
Chongqing Medicine 2024;53(18):2854-2859
Cardiovascular disease is one of the leading causes of death and health burden worldwide,se-riously affects the life quality of the patients.Therefore,it is essential to seek early identification,diagnosis and effective treatment method.At present,a large number of studies have shown that lncRNA is involved in the regulation of tumors,cardiocerebrovascular diseases and immune diseases through ceRNA and other mech-anisms.Among them,lncRNA plasmacytoma variant translocation gene 1 (PVT1) may become an important detection and therapeutic target by promoting fibrosis proliferation,inflammation,apoptosis,mitochondrial metabolism and other pathways to aggravate cardiac damage.However,the current research is scattered,and some of the research conclusions are different.Therefore,this article reviewed the latest research progress of lncRNA PVT1 in cardiovascular diseases,in order to provide a more comprehensive theoretical basis for basic research and clinical practice of cardiovascular diseases.
2.Reliability and Validity of Early Father-Child Relationship Scale in China
Xiao ZHANG ; Huichang CHEN ; Guifang ZHANG ; Bofang ZHOU ; Wei WU
Chinese Journal of Clinical Psychology 1993;0(01):-
Objective: To revise the Chinese version of Father-Child Relationship Scale(FCRS) and to examine its reliability and validity. Methods: Data were collected with Child-Parent Relationship Scale based on a sample of 400 young children and their fathers,retest was given after a month,and follow-up study was carried out to 106 children for 9 months. Results: The results of Confirmatory Factor Analysis showed a good fit to the data,and the examination of its criterion-related validity,by using children's behavior problems and social competence as criterions,also indicated that both the concurrent and the predictive validities of FCRS were satisfactory. The internal consistency reliability of FCRS was satisfactory,with Cronbach ? coefficient 0.71; and the test-retest reliability was also satisfactory,with test-retest correlation coefficient 0.68(P

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