The pathological mechanism of wound healing is complicated and affected by multiple factors. Modern wound dressings are widely used in the clinical management of wound healing and have achieved good therapeutic effects. Clinically, wounds are often caused by different etiologies. However, there are few reviews focus on the selection of reasonable dressings for different types of wounds. This study mainly focuses on the characteristics of commonly used wound dressings and summarizes the characteristics of the most commonly used wound dressings in clinical practice and their effects. The advantages and disadvantages of pathology wounds: diabetic foot ulcers, pressure injuries, burns, and leg ulcers are reviewed. This study aims to provide references for the development and clinical selection of wound dressings for scientific researchers and first-line nursing staff who are engaged in wound dressings.
Humans ; Bandages, Hydrocolloid ; Diabetic Foot/therapy* ; Wound Healing

Hydrocolloid dressings have been developed for many types of wound healing. In particular, dressing is a critical component in the successful recover of burn injuries, which causes a great number of people to not only suffer from physical but also psychological and economic anguish each year. Additionally, silk fibroin is the safest material for tissue engineering due to biocompatibility. In this study, we fabricated hydrocolloid dressings incorporating silk fibroin nanoparticles to enhance the efficacy of hydrocolloid dressing and then use this silk fibroin nanoparticle hydrocolloid dressing (SFNHD) in animal models to treat burn wounds. The structures and properties of SFNHD were characterized using tensile strength and Cell Counting Kit-8 assay. The results indicated the structural stability and the cellular biocompatibility of the hydrocolloid dressing suggesting that SFNHD can be applied to the treatment of wounds. To demonstrate the capacity of a silk fibroin hydrocolloid dressing to treat burn wounds, we compared SFNHD to gauze and Neoderm®, a commercially available dressing. This study clearly demonstrated accelerated wound healing with greater wound structural integrity and minimal wound size after treatment with SFNHD. These observations indicate that SFNHD may be an improvement upon current standard dressings such as Gauze and Neoderm® for burn wounds.
Bandages ; Bandages, Hydrocolloid* ; Burns ; Cell Count ; Colloids* ; Fibroins* ; Models, Animal ; Nanoparticles* ; Silk* ; Stress, Psychological ; Tensile Strength ; Tissue Engineering ; Wound Healing* ; Wounds and Injuries*

Over the past years, hydrocolloid dressings have been introduced routinely in the treatment of various types of wounds. They provide a moist environment promoting autolytic debridement, and stimulate angiogenesis. However, long-term application often leads to inflammation of the skin in the immediate area of the ulcer, causing irritant dermatitis in many cases, but sometimes also leads to contact sensitization. A 32 year-old woman burnt herself by an iron, and presented to our clinic and was treated with Duoderm extrathin(R). Nine days later, she again presented with an erythematous oozing patch with edema, and allergic contact dermatitis was suspected. A patch test (TRUE test) was performed and a positive reaction to colophonium was obtained. Duoderm extrathin(R) contains hydrogenated rosin (colophonium) as the tackifying agent, so we could diagnose this case as allergic contact dermatitis due to the hydrogenated rosin in Duoderm extrathin(R). We report another case of allergic contact dermatitis due to Duoderm extrathin(R) in a 32 year-old woman.
Bandages, Hydrocolloid ; Debridement ; Dermatitis, Allergic Contact ; Dermatitis, Irritant ; Edema ; Female ; Humans ; Hydrogen ; Inflammation ; Iron ; Patch Tests ; Resins, Plant ; Skin ; Ulcer

PURPOSE: A cutaneous wound healing requires a well-orchestrated integration of the complex biological and molecular events of cell migration and proliferation, extracellular matrix deposition, angiogenesis and remodeling. Finally, skin regeneration is the main goal. Stem cells are self-renewing multipotent progenitors with the broadest developmental potential in a given tissue at a given time. The aim of this study was to examine the role of stem cells during the wound healing process of cutaneous burn in hairless mice by using immunohistochemical stainings (nestin, cytokeratin 15 and CD31). METHODS: Each mouse received 2 burns at the dorsal area by applying a metal stick heated in boiling water. Burn wound sites were dressed with duoderm. The mice were sacrificed at 0, 2, 7, 14 and 21 days after burn. Histological findings and immunohistochemical expression for stem cell markers were observed. RESULTS: Nestin was expressed in the stromal cells beneath the epidermis, hair follices, dermal cysts and endothelial cells. Cytokeratin 15 was expressed in the epidermis except in basal cells. On 7 and 14 days after burn, the regenerated epidermis didn't express cytokeratin 15. CD31 was expressed in the endothelial cells on 7 and 14 days after burn. The amount of nestin expression was the highest. CONCLUSION: Our results showed that nestin may have various effects on burn wound healing. Cytokeratin 15 was expressed before burn and after burn. It is likely that other cytokeratin may stimulate epithelial regeneration. CD31 may act in vascular regeneration during burn healing.
Animals ; Bandages, Hydrocolloid ; Burns ; Cell Movement ; Endothelial Cells ; Epidermis ; Extracellular Matrix ; Hair ; Hot Temperature ; Intermediate Filament Proteins ; Keratin-15 ; Keratins ; Mice ; Mice, Hairless ; Nerve Tissue Proteins ; Regeneration ; Skin ; Stem Cells ; Stromal Cells ; Water ; Wound Healing

PURPOSE: The aim of this study was to examine the effects of silk fibroin film on wound healing of cutaneous burn in hairless mice by using microscopic findings and stem cell markers (nestin, cytokeratin 15) and ki-67 proliferation marker. METHODS: Each mouse received two burns at the dorsal area by applying a metal rod heated with boiling water. Burn wound sites were dressed with Silk Fibroin Film and duoderm (SF group), Aquacel hydrofiber and duoderm (AC group) and duoderm only (Control group). All groups were covered externally with duodermas adhesive bands. Those mice were sacrificed at zero, two, seven, fourteen and twenty one days after burn. Histological findings and immunohistochemical staining for stem cell markers were observed. RESULTS: In SF group, inflammatory cell infiltration, formation of granulation tissue and inflammatory foci are greater than in AC and control group. Those factors appear to enhance mesenchymal stem cell markers such as nestin. Finally mesenchymal tissue regeneration was enhanced. In addition, the length of ki-67 expressed re-generating epithelium, which appeared to be associated with epithelial regeneration, was the longest in SF group. CONCLUSION: The results show that the wound healing effect of SF is the best among other treatment materials including AC in the experimental group and duoderm in the control group through mesenchymal regeneration and epithelial regeneration which are essential factors for wound healing.
Adhesives ; Animals ; Bandages, Hydrocolloid ; Burns ; Carboxymethylcellulose Sodium ; Epithelium ; Fibroins ; Granulation Tissue ; Hot Temperature ; Intermediate Filament Proteins ; Keratins ; Mesenchymal Stromal Cells ; Mice ; Mice, Hairless ; Nerve Tissue Proteins ; Regeneration ; Silk ; Stem Cells ; Water ; Wound Healing

Allergic reaction to different fruits and vegetables has frequently been described, but an allergic reaction to mango fruit, including its sap, pericarp, stems and leaves, has rarely reported in the literature. Mango dermatitis, although not common, is the term for allergic contact dermatitis caused by mango. The Mango plant is found worldwide, and the plant shares chemical compounds that are similar to other substances of the Anacardiaceae plant. The substances uroshiol and cardol cause the allergic contact dermatitis. Any case of allergic contact dermatitis with eating mango fruit has not been reported in the Korean dermatologic literature. Here we report the first case of mango contact dermatitis in a 20-years-old female and this happened when she drank mango juice.
Anacardiaceae ; Bandages ; Bandages, Hydrocolloid ; Dermatitis ; Dermatitis, Allergic Contact ; Dermatitis, Contact ; Eating ; Female ; Fruit ; Humans ; Hypersensitivity ; Mangifera ; Plants ; Resorcinols ; Vegetables

Even though hydrocolloid dressings have been widely used for the past 15 years in the treatment of various types of wounds; allergic contact dermatitis to these dressings have been rarely reported. Duoderm(R) is representative agent of hydrocolloid dressing, and Duoderm Extrathin(R) is a new formulation of Duoderm(R) that contains pentaerythritol ester as a tacking agent, a substance used in several other adhesives. In Korean dermatologic literature, only 1 case of the allergic contact dermatitis due to Duoderm CGF(R) has been reported. However allergic contact dermatitis due to Duoderm Extrathin(R) has not been reported. We report a case of allergic contact dermatitis in a 22-year-old female during wound management using Duoderm Extrathin(R).
Adhesives ; Bandages ; Bandages, Hydrocolloid ; Colloids ; Dermatitis, Allergic Contact ; Female ; Humans ; Propylene Glycols ; Young Adult

PURPOSE: To compare the effectiveness between wearing a conventional hydrogel vifilcon A bandage contact lens (BCL) and a silicone hydrogel lotrafilcon A BCL after laser-assisted subepithelial keratomileusis (LASEK). METHODS: LASEK was performed on 38 eyes of 19 patients. Each patient was fitted with a silicone hydrogel lotrafilcon A lens in one eye and a conventional hydrogel vifilcon A lens in the other eye. The patient was masked on the type of lens in each eye. General preference between the two types of lenses, subjective symptoms (pain, photophobia, tearing, dryness, and foreign body sensation; graded as 0 to 4), and the area of non-viable corneal epithelium were assessed in each eye at one and four days after surgery. RESULTS: Patients reported preferring the lotrafilcon A lens to vifilcon A at 1 (79%) and 4 (74%) days after LASEK. The mean symptom scores of tearing and foreign body sensation at 1 day after surgery (P=0.012 and P=0.034, respectively) and foreign body sensation at 4 days after surgery (P=0.027) were significantly lower in the lotrafilcon A group. The mean area of the non-viable corneal epithelium was smaller in the lotrafilcon A lens group at 1 day and 4 days after surgery, although not statistically significant. CONCLUSIONS: Patients better tolerated the silicone hydrogel lotrafilcon A BCL compared with the conventional hydrogel vifilcon A BCL. The mean symptom scores were significantly lower in the lotrafilcon A group at both 1 and 4 days after LASEK.
Bandages ; Bandages, Hydrocolloid* ; Epithelium, Corneal ; Foreign Bodies ; Humans ; Hydrogel* ; Keratectomy, Subepithelial, Laser-Assisted* ; Masks ; Photophobia ; Sensation ; Silicones*

Pressure sores are a common complication of hospitalized patients. However, It is often impossible to correct surgically because the general conditions of these patients are poor. It is known that the hydrogel has a powerful autolytic effect by providing moist environments and facilitates wound healing and hydrocolloid dressing is also known to promotes granulation tissue formation and epithelialization. The patients were treated with hydrogel(Purion gel(R), Coloplast A/S, Denmark) and hydrocolloid dressing (Comfeel Plus Transparent Dressing(R), Coloplast A/S, Denmark) after surgical debridement of pressure sores progressed to stage III(n=2) and IV(n=7). This combination treatment could facilitate to debride the nectrotic tissue and promote granulation tissue formation epithelialization simultaneously. We could achieve complete healing of pressure sores using the combination treatment without requiring surgical correction. In conclusion, hydrogel in combination with hydrocolloid dressing is effective in acheiving complete healing of progressed pressure sores.
Bandages, Hydrocolloid* ; Colloids* ; Debridement ; Granulation Tissue ; Humans ; Hydrogel* ; Pressure Ulcer* ; Wound Healing

Synthetic burn dressing remains the central theme for burn dressing development. The advantages and disadvantages of current available dressings were reviewed. As one of the most successful dressings, the hydrogel burn dressing, its combination with other materials and related progress in researches were presented in detail. Finally, the trend in development of synthetic burn dressing was presented.
Bandages, Hydrocolloid ; Burns ; therapy