2.The Complexity of Pediatric Multifocal Atrial Tachycardia and Its Prognostic Factors
Seung Min BAEK ; Hyun CHUNG ; Mi Kyoung SONG ; Eun Jung BAE ; Gi Beom KIM ; Chung Il NOH
Korean Circulation Journal 2018;48(2):148-158
		                        		
		                        			
		                        			BACKGROUND AND OBJECTIVES: Multifocal atrial tachycardia (MAT), in general, has a favorable outcome. However, there are insufficient data regarding MAT in a pediatric population. This study sought to determine the clinical course of MAT and identify potential prognostic factors. METHODS: The medical records of MAT patients from 1997–2015 were reviewed. The arrhythmia control rate and factors for unfavorable outcomes were assessed and compared to those in the literature. RESULTS: Of the 33 included patients (19 boys and 14 girls), 27 were infants less than 1 year of age. The median age at diagnosis was 1.7 months (range, 0 day to 14 years). Fourteen (42%) patients had structural heart disease. Eight (24%) patients had lung disease and 6 (18%) had a syndromic diagnosis belonging to RASopathy. Two patients developed polymorphic ventricular tachycardia, in whom genetic analysis confirmed the presence of the RyR2 mutation several years later. MAT was controlled in 26 patients (84%) within 3.9 months (median; range, 16 days–18.4 years) using an average of 2.4 medications. There were 3 cases of cardiopulmonary mortality. The arrhythmia control rate was higher in the infant group (85%) than in the non-infant group (67%), although this trend was not statistically significant. There was a significantly lower rate of unfavorable outcomes in the idiopathic infant group (n=11) than in the other groups (p=0.008). Considering the findings of previous studies, the mortality rate was significantly higher in patients with structural heart disease than in patients without (21% vs. 5%, p=0.01). CONCLUSIONS: MAT usually affects infants and has a favorable prognosis, particularly in the idiopathic infant group. However, in the presence of other comorbidities, MAT may have a variable clinical course.
		                        		
		                        		
		                        		
		                        			Arrhythmias, Cardiac
		                        			;
		                        		
		                        			Atrial Fibrillation
		                        			;
		                        		
		                        			Atrial Flutter
		                        			;
		                        		
		                        			Comorbidity
		                        			;
		                        		
		                        			Diagnosis
		                        			;
		                        		
		                        			Heart Diseases
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Infant
		                        			;
		                        		
		                        			Lung Diseases
		                        			;
		                        		
		                        			Medical Records
		                        			;
		                        		
		                        			Mortality
		                        			;
		                        		
		                        			Prognosis
		                        			;
		                        		
		                        			Ryanodine Receptor Calcium Release Channel
		                        			;
		                        		
		                        			Tachycardia
		                        			;
		                        		
		                        			Tachycardia, Supraventricular
		                        			;
		                        		
		                        			Tachycardia, Ventricular
		                        			
		                        		
		                        	
3.Silent Left Large Atrial Myxoma: A Patient with Serial Electrocardiogram Variation.
Yogarabindranath Swarna NANTHA ; Shadidah Abdul MALEK
Korean Journal of Family Medicine 2017;38(4):229-232
		                        		
		                        			
		                        			Cardiac myxoma is often discovered as an incidental finding and presents with various subtle symptoms and signs. Electrocardiographic findings are mostly non-specific. Atrial flutter or conduction abnormalities are known to be rare. We report a case of large left atrial myxoma that was diagnosed by transthoracic echocardiography at a primary care clinic. An asymptomatic, 71-year-old woman presented with serial abnormal electrocardiogram changes during a routine consultation. A diagnosis of left atrial myxoma was obtained through transthoracic echocardiography. We report this case with a review of literature on cardiac myxoma associated with arrhythmia.
		                        		
		                        		
		                        		
		                        			Aged
		                        			;
		                        		
		                        			Arrhythmias, Cardiac
		                        			;
		                        		
		                        			Atrial Fibrillation
		                        			;
		                        		
		                        			Atrial Flutter
		                        			;
		                        		
		                        			Diagnosis
		                        			;
		                        		
		                        			Echocardiography
		                        			;
		                        		
		                        			Electrocardiography*
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Incidental Findings
		                        			;
		                        		
		                        			Myxoma*
		                        			;
		                        		
		                        			Primary Health Care
		                        			
		                        		
		                        	
4.Differential Diagnosis of Supraventricular Tachycardia.
International Journal of Arrhythmia 2017;18(1):43-47
		                        		
		                        			
		                        			Supraventricular tachycardia (SVT) refers to a heterogeneous group of arrhythmias localized within the upper part of the heart (the His bundle or above). In general, the term SVT does not include atrial fibrillation. Common forms of SVT include atrioventricular nodal reentrant tachycardia, atrioventricular reentrant tachycardia, focal atrial tachycardia, and atrial flutter. Other, less common arrhythmias also fall under the category of SVT, including inappropriate sinus tachycardia and junctional reentrant/ectopic tachycardia. Paroxysmal supraventricular tachycardia refers to AVNRT and AVRT. SVTs can be identified and classified by clinical manifestation/physical examination, ECG, and/or electrophysiologic analysis.
		                        		
		                        		
		                        		
		                        			Arrhythmias, Cardiac
		                        			;
		                        		
		                        			Atrial Fibrillation
		                        			;
		                        		
		                        			Atrial Flutter
		                        			;
		                        		
		                        			Bundle of His
		                        			;
		                        		
		                        			Diagnosis, Differential*
		                        			;
		                        		
		                        			Electrocardiography
		                        			;
		                        		
		                        			Heart
		                        			;
		                        		
		                        			Tachycardia
		                        			;
		                        		
		                        			Tachycardia, Atrioventricular Nodal Reentry
		                        			;
		                        		
		                        			Tachycardia, Sinus
		                        			;
		                        		
		                        			Tachycardia, Supraventricular*
		                        			
		                        		
		                        	
5.Analysis of clinical characteristics and causes of chest pain in children and adolescents.
Ji Hye CHUN ; Tae Hyeong KIM ; Mi Young HAN ; Na Yeon KIM ; Kyung Lim YOON
Korean Journal of Pediatrics 2015;58(11):440-445
		                        		
		                        			
		                        			PURPOSE: Chest pain is common in children and adolescents and is a reason for referral to pediatric cardiologists. Although most cases of chest pain in these age groups are benign and do not require treatment, timely diagnosis is important not to miss life-threatening diseases requiring prompt treatment. We investigated certain clinical characteristics that may be useful in the diagnosis of such critical diseases. METHODS: Patient medical records between July 2006 and September 2013 were retrospectively examined. We included 517 patients who presented with chest pain to the Department of Pediatrics at Kyung Hee University Hospital in Gangdong. RESULTS: Most cases of chest pain were idiopathic in origin (73.6%), followed by cases with respiratory (9.3%), musculoskeletal (8.8%), cardiac (3.8%), gastrointestinal (2.9%), and psychiatric (1.4%) causes. In 6 patients (1.2%) with air-leak syndrome including pneumothorax or pneumomediastinum, the pain was abrupt, continuous, and lasted for a short period of 1-2 days after onset in the older adolescents. Of the patients with cardiac pain, 13 had cardiac arrhythmias (65.0%), 6 had congenital heart diseases (30%), and 1 had coronary aneurysms caused by Kawasaki disease (5.0%). One patient with atrial flutter had only symptoms of syncope and chest pain. CONCLUSION: The abrupt, continuous chest pain of a short duration in the older children was characteristic of air-leak syndrome. In patients with pneumomediastinum, radiological diagnosis was difficult without careful examination. Combined syncope should not be neglected and further cardiac workup is essential in such patients.
		                        		
		                        		
		                        		
		                        			Adolescent*
		                        			;
		                        		
		                        			Arrhythmias, Cardiac
		                        			;
		                        		
		                        			Atrial Flutter
		                        			;
		                        		
		                        			Chest Pain*
		                        			;
		                        		
		                        			Child*
		                        			;
		                        		
		                        			Coronary Aneurysm
		                        			;
		                        		
		                        			Diagnosis
		                        			;
		                        		
		                        			Heart Diseases
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Mediastinal Emphysema
		                        			;
		                        		
		                        			Medical Records
		                        			;
		                        		
		                        			Mucocutaneous Lymph Node Syndrome
		                        			;
		                        		
		                        			Musculoskeletal Diseases
		                        			;
		                        		
		                        			Pediatrics
		                        			;
		                        		
		                        			Pneumothorax
		                        			;
		                        		
		                        			Referral and Consultation
		                        			;
		                        		
		                        			Retrospective Studies
		                        			;
		                        		
		                        			Syncope
		                        			;
		                        		
		                        			Thorax*
		                        			
		                        		
		                        	
6.A tale of two tachycardias.
Colin YEO ; Jeremy CHOW ; Gerard LEONG ; Kah Leng HO
Singapore medical journal 2015;56(1):e10-3
		                        		
		                        			
		                        			A patient with non-ischaemic cardiomyopathy, and pre-existing atypical atrial flutter and left bundle branch block, developed broad complex tachycardia. In this unique and uncommon case of double tachycardia, we discuss the diagnostic approach of ventricular tachycardia in patients with broad complex tachycardia, and the use of different contemporary algorithms to help diagnose ventricular tachycardia and differentiate it from supraventricular tachycardia with aberrant conduction.
		                        		
		                        		
		                        		
		                        			Algorithms
		                        			;
		                        		
		                        			Atrial Flutter
		                        			;
		                        		
		                        			complications
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			Bundle-Branch Block
		                        			;
		                        		
		                        			physiopathology
		                        			;
		                        		
		                        			Cardiomyopathies
		                        			;
		                        		
		                        			complications
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			Diagnosis, Differential
		                        			;
		                        		
		                        			Echocardiography
		                        			;
		                        		
		                        			Electrocardiography
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Tachycardia, Supraventricular
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			physiopathology
		                        			;
		                        		
		                        			Tachycardia, Ventricular
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			physiopathology
		                        			
		                        		
		                        	
7.Acute Myocardial Infarction after Radiofrequency Catheter Ablation of Typical Atrial Flutter.
Sehyo YUNE ; Woo Joo LEE ; Ji won HWANG ; Eun KIM ; Jung Min HA ; June Soo KIM
Journal of Korean Medical Science 2014;29(2):292-295
		                        		
		                        			
		                        			A 53-yr-old man underwent radiofrequency ablation to treat persistent atrial flutter. After the procedure, the chest pain was getting worse, and the electrocardiogram showed ST-segment elevation in inferior leads with reciprocal changes. Immediate coronary angiography showed total occlusion with thrombi at the distal portion of the right coronary artery, which was very close to the ablation site. Intervention with thrombus aspiration and balloon dilatation was successful, and the patient recovered without any kind of sequelae. Although the exact mechanism is obscure, the most likely explanation is a thermal injury to the vascular wall that ruptured into the lumen and formed thrombus. Vasospasm and thromboembolism can also be other possibilities. This case raise the alarm to cardiologists who perform radiofrequency ablation to treat various kinds of cardiac arrhythmias, in that myocardial infarction has been rarely considered one of the complications.
		                        		
		                        		
		                        		
		                        			Acute Disease
		                        			;
		                        		
		                        			Angioplasty, Balloon, Coronary
		                        			;
		                        		
		                        			Atrial Flutter/*surgery
		                        			;
		                        		
		                        			Catheter Ablation/*adverse effects
		                        			;
		                        		
		                        			Chest Pain/etiology
		                        			;
		                        		
		                        			Coronary Occlusion/etiology
		                        			;
		                        		
		                        			Coronary Vessels/radiography
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Myocardial Infarction/*diagnosis/etiology/therapy
		                        			;
		                        		
		                        			Thrombosis/surgery
		                        			
		                        		
		                        	
8.Fetal atrial flutter in two cases with structurally normal hearts.
Shan LU ; Tong-Yan HAN ; Yan-Mei CHANG ; Yun-Pu CUI ; Xiao-Feng CHEN
Chinese Journal of Contemporary Pediatrics 2014;16(3):313-314
		                        		
		                        		
		                        		
		                        			Atrial Flutter
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			drug therapy
		                        			;
		                        		
		                        			physiopathology
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Infant, Newborn
		                        			;
		                        		
		                        			Male
		                        			
		                        		
		                        	
9.Tachyarrhythmia:Prenatal Diagnosis, Management and Perinatal Outcome.
Eui JUNG ; Hye Sung WON ; Sun Kwon KIM ; Jae Yoon SHIM ; Pil Ryang LEE ; Ahm KIM ; In Sook PARK
Korean Journal of Perinatology 2005;16(3):230-236
		                        		
		                        			
		                        			OBJECTIVE: To review the diagnosis, treatment, and perinatal outcome of fetal tachyarrhythmias. METHODS: We reviewed the medical records of pregnant women diagnosed with fetal tachyarrhythmia at Asan Medical Center from June 1997 to December 2004. Tachyarrhythmias were classified as either supraventricular tachycardia (SVT) or atrial flutter (AF), and the intrauterine management and long-term outcomes of the infants were analyzed. RESULTS: There were three cases of SVT and four cases of AF. Fetal hydrops was noted in 4 of 7 fetuses and there were no cardiac anomalies. All of them were treated in utero with antiarrhythmic agents including digoxin and flecainide. During antiarrhythmic therapy, sinus rhythm was achieved in 100% of them and the survival rate was 100%. Two infants diagnosed prenatally with SVT developed Wolff-Parkinson-White syndrome after birth. One of them developed paroxysmal SVT but after adenosine treatment she needed no treatment. One fetus with AF was diagnosed with an atrial ectopic tachyarrhythmia postnatally which needed medication for one year and resulted in normal sinus rhythm. At the time of this study, all of them showed normal development without neurological morbidity. CONCLUSION: Fetal tachyarrhythmias diagnosed prenatally can be effectively treated with antiarrhythmic drugs in utero or postnatally even if they had hydropic feature. So they must be referred to a tertiary care center for appropriate counseling and management. We recommend that every SVT or AF should be treated in utero regardless of the presence of hydrops.
		                        		
		                        		
		                        		
		                        			Adenosine
		                        			;
		                        		
		                        			Anti-Arrhythmia Agents
		                        			;
		                        		
		                        			Atrial Flutter
		                        			;
		                        		
		                        			Chungcheongnam-do
		                        			;
		                        		
		                        			Counseling
		                        			;
		                        		
		                        			Diagnosis*
		                        			;
		                        		
		                        			Digoxin
		                        			;
		                        		
		                        			Edema
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Fetus
		                        			;
		                        		
		                        			Flecainide
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Hydrops Fetalis
		                        			;
		                        		
		                        			Infant
		                        			;
		                        		
		                        			Medical Records
		                        			;
		                        		
		                        			Parturition
		                        			;
		                        		
		                        			Pregnant Women
		                        			;
		                        		
		                        			Survival Rate
		                        			;
		                        		
		                        			Tachycardia
		                        			;
		                        		
		                        			Tachycardia, Supraventricular
		                        			;
		                        		
		                        			Tertiary Care Centers
		                        			;
		                        		
		                        			Wolff-Parkinson-White Syndrome
		                        			
		                        		
		                        	
10.Clinical Review of Inappropriate Use of Adenosine in Tachycardic Patients at the Emergency Department.
Dong Hyuk SINN ; Keun Jeong SONG ; Byung Seop SHIN ; Pil Cho CHOI
Journal of the Korean Society of Emergency Medicine 2004;15(5):331-336
		                        		
		                        			
		                        			PURPOSE: For tachycardic patients not in need of immediate cardioversion, the International Guidelines 2000 for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care emphasize specific rhythm diagnosis and avoidance of simplistic overuse of adenosine. The purpose of this study was to identify the rhythms for which adenosine was inappropriately prescribed at the emergency department after the International Guidelines 2000 had been adopted. METHODS: We retrospectively investigated 128 tachycardic patients who had been prescribed adenosine at the emergency department from September 2000 to March 2003. Patients were divided into two groups. The Appropriate Use Group was comprised of patients for whom had been prescribed for narrow QRS-complex tachycardia on the initial ECG. The Inappropriate Use Group was comprised of patients for whom adenosine had been prescribed for atrial fibrillation, atrial flutter, atrial tachycardia, sinus tachycardia, and wide QRS-complex tachycardia of unknown origin on the initial ECG. RESULTS: Of the 128 patients, 31 (24.2%) were in the Inappropriate Use Group. Among them, atrial fibrillation was involved in 15, atrial flutter in 3, atrial tachycardia in 2, sinus tachycardia in 8, and wide QRS-complex tachycardia of unknown origin in 3. CONCLUSION: Approximately 24% of the emergency department patients who were treated with adenosine received the medication unnecessarily for atrial fibrillation, atrial flutter, atrial tachycardia, sinus tachycardia, and wide QRS-complex tachycardia of unknown origin. Additional education on electrocardiographic recognition of tachyarrhythmias, and the Tachycardia Algorithms of Guidelines 2000 may be necessary for residents of emergency department.
		                        		
		                        		
		                        		
		                        			Adenosine*
		                        			;
		                        		
		                        			Atrial Fibrillation
		                        			;
		                        		
		                        			Atrial Flutter
		                        			;
		                        		
		                        			Cardiopulmonary Resuscitation
		                        			;
		                        		
		                        			Diagnosis
		                        			;
		                        		
		                        			Education
		                        			;
		                        		
		                        			Electric Countershock
		                        			;
		                        		
		                        			Electrocardiography
		                        			;
		                        		
		                        			Emergencies*
		                        			;
		                        		
		                        			Emergency Service, Hospital*
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Retrospective Studies
		                        			;
		                        		
		                        			Tachycardia
		                        			;
		                        		
		                        			Tachycardia, Sinus
		                        			
		                        		
		                        	
            
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