3.Etiology of ascites in 165 children.
Yong WANG ; Sheng-Hua WAN ; Chun-Lei ZHAN ; Zhen-Jun XIAO ; Xiao-Fen LIU ; Na LI
Chinese Journal of Contemporary Pediatrics 2022;24(4):382-386
OBJECTIVES:
To study the etiology and clinical features of children with ascites, so as to provide a basis for the diagnosis and treatment of ascites in children.
METHODS:
The medical data of the children with ascites, who were hospitalized from January 1, 2010 to December 31, 2019, were retrospectively reviewed.
RESULTS:
Among the 165 children with ascites, the male/female ratio was 1.53:1, and the mean age of onset was (6±4) years. The causes of ascites included surgical acute abdomen (39 children, 23.6%), infectious diseases (39 children, 23.6%), neoplastic diseases (27 children, 16.4%), hepatogenic diseases (18 children, 10.9%), pancreatitis (10 children, 6.1%), cardiogenic diseases (8 children, 4.8%), rheumatic immune diseases (6 children, 3.6%), and nephrogenic diseases (5 children, 3.0%). According to the age of onset, there were 33 infants, 24 young children, 30 preschool children, 41 school-aged children, and 37 adolescents. Surgical acute abdomen and hepatogenic diseases were the main causes of ascites in infants (P<0.05). Neoplastic disease was the leading cause in young children (P<0.05). Infectious diseases were the most common cause in adolescents (P<0.05).
CONCLUSIONS
Surgical acute abdomen, infectious diseases, neoplastic diseases, and hepatogenic diseases are the common causes of ascites in children, and there are some differences in the leading cause of ascites between different age groups.
Abdomen, Acute/complications*
;
Adolescent
;
Ascites/etiology*
;
Child
;
Child, Preschool
;
Communicable Diseases
;
Female
;
Humans
;
Infant
;
Male
;
Neoplasms/complications*
;
Pancreatitis/complications*
;
Retrospective Studies
4.Factors associated with surgical morbidity of primary debulking in epithelial ovarian cancer
Emre GÜNAKAN ; Yusuf Aytaç TOHMA ; Mehmet TUNÇ ; Hüseyin AKILLI ; Hanifi ŞAHIN ; Ali AYHAN
Obstetrics & Gynecology Science 2020;63(1):64-71
complications that occurred within 30 days after the surgery and factors that affect morbidity were considered.RESULTS: The study involved 359 patients. Forty-six intraoperative complications occurred in 42 (11.6%) patients. Advanced stage and cancer antigen level of 125 were independently and significantly associated with operative complications (hazard ratio [HR], 1.66; 95% confidence interval [CI], 1.01–2,73; P=0.044, and HR, 1.47; 95% CI, 1.05–2.06; P=0.025, respectively). The need for intensive care unit admission was significantly higher in patients with intraoperative complications (28.6% vs. 8.8%, P=0.001). Intraoperative and postoperative complication rates were significantly higher in extended surgery than in standard surgery (18.9%vs. 8.5%, P=0.005 and 38.7% vs. 10.9%, P < 0.001, respectively). Intraoperative and postoperative transfusion need, hospital stay duration, and chemotherapy start day were also significantly higher in extended surgery than in standard surgery. Hundred postoperative complications occurred in 70 patients. Age, extended surgery, presence of ascites, and presence of operative complications were independently and significantly associated with postoperative complications.CONCLUSION: Morbidity of extensive surgical approach should be kept in mind in ovarian cancer surgery aimed at leaving no residual tumor. Patient-based management with an appropriate preoperative evaluation may avoid morbidity of extended/extensive surgical approaches.]]>
Ascites
;
Drug Therapy
;
Humans
;
Intensive Care Units
;
Intraoperative Complications
;
Length of Stay
;
Neoplasm, Residual
;
Ovarian Neoplasms
;
Postoperative Complications
5.Intermittent abdominal pain and abdominal distension with fatigue and massive ascites in a 13-year-old boy.
Tian ZHANG ; Hui ZHANG ; Tao FANG ; Ao XU ; Ming-Wu CHEN
Chinese Journal of Contemporary Pediatrics 2019;21(3):277-281
A 13-year-old boy was admitted due to intermittent abdominal pain for one year with massive ascites. The purified protein derivative (PPD) test after admission yielded positive results (3+), and ascites examination revealed a yellow color. There were 634×10 nucleated cells/L in the ascites, among which 82.2% were mononuclear cells and 17.8% were multinuclear cells. The Rivalta test yielded a positive result and revealed that the ascites was exudate, suggesting the possibility of tuberculosis infection. The symptoms were not relieved after isoniazid-rifampicin anti-tuberculosis therapy and symptomatic/supportive treatment. Plain CT scan of the abdomen and contrast-enhanced CT showed that the lesion was located at the left wall of the transverse colon, with uneven thickening of the peritoneum and heterogeneous enhancement. Colonoscopic biopsy found signet ring cells in the mucosa and immunohistochemical examination revealed Syn (-), CgA (-), CD56 (-), CK(pan) (+), CDX-2 (+), CK20 (+), Muc-1 (+) and Ki-67 (+, about 80%). PET-CT scan showed an abnormal increase in fluorodeoxyglucose metabolism, which was shown as a mass near the splenic flexure of the transverse colon, with a maximum standard uptake value of 9.9, indicating a highly active lesion; this was consistent with the metabolic changes of malignant tumors. Surgical operation was performed and intraoperative exploration revealed massive ascites, a hard mass located at the hepatic flexure of the colon, involvement of the serous coat and surrounding tissues, stenosis of the bowel, lymph node enlargement around the superior mesenteric vessels and the gastrocolic ligament, and multiple metastatic nodules in the greater omentum, the abdominal wall and the pelvic cavity. The results of postoperative pathology were consistent with those of colonoscopic biopsy, i.e., poorly differentiated mucinous adenocarcinoma of the transverse colon and partly signet-ring cell carcinoma. Therefore, the boy was diagnosed with colon signet-ring cell carcinoma with peritoneal metastasis and tuberculosis infection. When a child is suffering from intractable abdominal pain, unexplained intestinal obstruction and massive intractable ascites, the possibility of malignancy should be considered. Abdominal plain CT scan as well as contrast-enhanced CT scan should be performed as early as possible, and enteroscopy should be performed when necessary.
Abdomen
;
Abdominal Pain
;
etiology
;
Adolescent
;
Ascites
;
complications
;
Fatigue
;
etiology
;
Humans
;
Male
;
Positron Emission Tomography Computed Tomography
;
Tomography, X-Ray Computed
6.Umbilical needling therapy of I-Ching at 1 PM to 3 PM for cirrhosis ascites with syndrome of spleen-deficiency and fluid-retention.
Chinese Acupuncture & Moxibustion 2019;39(7):713-716
OBJECTIVE:
To observe the clinical efficacy of umbilical needling therapy of I-Ching at 1 PM to 3 PM for cirrhosis ascites with syndrome of spleen-deficiency and fluid-retention.
METHODS:
Forty-eight patients of cirrhosis ascites with syndrome of spleen-deficiency and fluid-retention were randomly divided into an observation group and a control group, 24 cases in each one. Both groups were treated with routine treatment of western medicine combined with TCM decoction. In addition, the patients in the observation group were treated with umbilical needling therapy of I-Ching at locations of , , and . The treatment was given at 1 PM to 3 PM, once a day; 10-d treatment was a course of treatment, and a total of 20-d treatment was given. The abdominal circumference, urine volume, body mass, liver function and prothrombin time were observed before and after treatment in the two groups, and the clinical efficacy of the two groups was compared.
RESULTS:
The total effective rate was 91.7% (22/24) in the observation group, which was higher than 87.5% (21/24) in the control group (<0.05). After treatment, the improvement of abdominal circumference, urine volume, body mass, liver function and prothrombin time between the two groups was significantly different (<0.05), the observation group was better.
CONCLUSION
Based on the western medicine treatment, the combination of TCM decoction and umbilical needling therapy of I-Ching shows significant efficacy for cirrhosis ascites with syndrome of spleen-deficiency and fluid-retention.
Ascites
;
etiology
;
therapy
;
Humans
;
Liver Cirrhosis
;
complications
;
Needles
;
Spleen
;
Syndrome
;
Umbilicus
7.Resolution of Protein-Losing Enteropathy after Congenital Heart Disease Repair by Selective Lymphatic Embolization
Ranjit I KYLAT ; Marlys H WITTE ; Brent J BARBER ; Yoav DORI ; Fayez K GHISHAN
Pediatric Gastroenterology, Hepatology & Nutrition 2019;22(6):594-600
With improving survival of children with complex congenital heart disease (CCHD), postoperative complications, like protein-losing enteropathy (PLE) are increasingly encountered. A 3-year-old girl with surgically corrected CCHD (ventricular inversion/L-transposition of the great arteries, ventricular septal defect, pulmonary atresia, post-double switch procedure [Rastelli and Glenn]) developed chylothoraces. She was treated with pleurodesis, thoracic duct ligation and subsequently developed chylous ascites and PLE (serum albumin ≤0.9 g/dL) and was malnourished, despite nutritional rehabilitation. Lymphangioscintigraphy/single-photon emission computed tomography showed lymphatic obstruction at the cisterna chyli level. A segmental chyle leak and chylous lymphangiectasia were confirmed by gastrointestinal endoscopy, magnetic resonance (MR) enterography, and MR lymphangiography. Selective glue embolization of leaking intestinal lymphatic trunks led to prompt reversal of PLE. Serum albumin level and weight gain markedly improved and have been maintained for over 3 years. Selective interventional embolization reversed this devastating lymphatic complication of surgically corrected CCHD.
Adhesives
;
Arteries
;
Cardiac Surgical Procedures
;
Child
;
Child, Preschool
;
Chyle
;
Chylous Ascites
;
Embolization, Therapeutic
;
Endoscopy, Gastrointestinal
;
Female
;
Heart Defects, Congenital
;
Heart Septal Defects, Ventricular
;
Humans
;
Ligation
;
Lymphatic Abnormalities
;
Lymphography
;
Pleurodesis
;
Postoperative Complications
;
Protein-Losing Enteropathies
;
Pulmonary Atresia
;
Rehabilitation
;
Serum Albumin
;
Thoracic Duct
;
Tomography, Emission-Computed
;
Weight Gain
8.Early versus late surgical management for complicated appendicitis in adults: a multicenter propensity score matching study
Jeong Yeon KIM ; Jong Wan KIM ; Jun Ho PARK ; Byung Chun KIM ; Sang Nam YOON
Annals of Surgical Treatment and Research 2019;97(2):103-111
PURPOSE: Surgeons may be uncertain about the optimal timing of appendectomy to decrease complications, especially for complicated appendicitis. The aim of the study was to compare clinical outcomes between early and late surgery for complicated appendicitis. METHODS: A prospectively maintained database of complicated appendicitis was queried. Elective interval surgery (EIS) group and early surgery (ES) were matched with propensity score and marked with a prefix ‘p.’ Patient characteristics and surgical outcomes were compared. RESULTS: The propensity score-matched EIS group had a lower chance to underwent ileo-cecectomy or right hemicolectomy (1.5% vs. 6.9%, P = 0.031), a tendency of lower rate of postoperative complication (6.9% vs. 13.7%, P = 0.067), a lower rate of wound infection (1.5% vs. 8.4%, P = 0.010), and shorter postoperative hospital stay (3.72 days vs. 5.82 days, P < 0.001) than the propensity score-matched ES group. Multivariate analysis showed that delayed surgery for more than 48 hours or urgent surgery due to failure of EIS and open conversion were independent risk factors for postoperative complications (P = 0.001 and P = 0.025, respectively). In subgroup analysis, high American Society of Anesthesiologists physical status classification and distant abscess or generalized ascites in initial CT increased the risk of failure of EIS. CONCLUSION: EIS can be a useful option for selected adult patients with complicated appendicitis.
Abscess
;
Adult
;
Appendectomy
;
Appendicitis
;
Ascites
;
Classification
;
Humans
;
Length of Stay
;
Multivariate Analysis
;
Postoperative Complications
;
Propensity Score
;
Prospective Studies
;
Risk Factors
;
Surgeons
;
Wound Infection
9.Clinical guidelines on nutrition in end-stage liver disease.
Chinese Journal of Hepatology 2019;27(5):330-342
Malnutrition is common in patients with end-stage liver disease (ESLD) and is an independent risk factor for survival, therefore it should be treated as the same important guideline as ascites and hepatic encephalopathy. However, up to now, there is no clinical nutrition guideline for patients with ESLD in China. In order to standardize the nutrition treatment, Chinese Society of Hepatology (CSH) and Chinese Society of Gastroenterology (CSGE), Chinese Medical Association(CMA) co-organized and co-developed this guideline. Recommendations on nutritional screening and assessment as well as principles of intervention and management in patients with ESLD were provided to help clinicians make rational decisions on clinical malnutrition.
Ascites
;
China
;
End Stage Liver Disease/physiopathology*
;
Enteral Nutrition/standards*
;
Gastroenterology/standards*
;
Hepatic Encephalopathy
;
Humans
;
Liver Cirrhosis/complications*
;
Malnutrition/physiopathology*
;
Nutrition Assessment
;
Nutritional Status
;
Practice Guidelines as Topic
10.Low-dose radiation therapy for massive chylous leakage after subtotal gastrectomy.
Radiation Oncology Journal 2017;35(4):380-384
Massive chylous leakage is a rare postoperative complication that can prolong hospital stay and cause secondary morbidities. Conservative management strategies are the treatment of choice; however, radiation therapy (RT) can be used as an alternative for cases that are refractory to conservative treatment. Herein, we report a 69-year-old female patient who suffered from massive chylous leakage after subtotal gastrectomy. Due to persistent massive chylous leakage, she was scheduled to undergo low-dose RT. Radiation was delivered with a daily dose of 1 Gy, using an anterior-posterior and posterior-anterior beam arrangement. The clinical target volume encompassed the entire lymph node area of the D2 dissection. RT was completed at the total dose of 8 Gy because the amount of chylous leakage declined rapidly. Percutaneous drainage tube was removed after 3 days of RT. The patient did not complain of any symptoms related to massive chylous leakage 2 years after the completion of RT.
Aged
;
Chylous Ascites
;
Drainage
;
Female
;
Gastrectomy*
;
Humans
;
Length of Stay
;
Lymph Nodes
;
Postoperative Complications
;
Radiotherapy

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