3.Drug treatment of dyslipidemia.
Journal of the Korean Medical Association 2016;59(5):366-373
		                        		
		                        			
		                        			The ultimate objective of dyslipidemia management is to prevent and treat atherosclerotic cardiovascular diseases. It is important to combine lifestyle modification together with medication. To determine whether to start drug therapy, comprehensive consideration should be given to both the risk status for atherosclerotic cardiovascular disease and low density lipoprotein cholesterol levels. Drug treatment can be initiated according to whether the patients have coronary artery disease, ischemic cerebral infarction, peripheral artery disease, atherosclerotic artery diseases (abdominal aortic aneurysm, carotid artery stenosis), or diabetes, as well as the number of atherosclerotic risk factors (smoking, hypertension, low high density lipoprotein cholesterol level, family history of premature coronary artery disease, and age). Statin is the first-choice drug for the treatment of hypercholesterolemia. The first goal for drug therapy is to lower the low density lipoprotein cholesterol and the secondary goal is to lower the non-high density lipoprotein cholesterol level. Secondary causes of dyslipidemia should be considered and corrected before starting any medication. These recommendations are based on the new treatment guideline 2015 of Korean Society of Lipidology and Atherosclereosis and Korean Medical Association.
		                        		
		                        		
		                        		
		                        			Aortic Aneurysm
		                        			;
		                        		
		                        			Arteries
		                        			;
		                        		
		                        			Cardiovascular Diseases
		                        			;
		                        		
		                        			Carotid Arteries
		                        			;
		                        		
		                        			Cerebral Infarction
		                        			;
		                        		
		                        			Cholesterol
		                        			;
		                        		
		                        			Cholesterol, HDL
		                        			;
		                        		
		                        			Cholesterol, LDL
		                        			;
		                        		
		                        			Coronary Artery Disease
		                        			;
		                        		
		                        			Drug Therapy
		                        			;
		                        		
		                        			Dyslipidemias*
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Hydroxymethylglutaryl-CoA Reductase Inhibitors
		                        			;
		                        		
		                        			Hypercholesterolemia
		                        			;
		                        		
		                        			Hypertension
		                        			;
		                        		
		                        			Life Style
		                        			;
		                        		
		                        			Lipoproteins
		                        			;
		                        		
		                        			Peripheral Arterial Disease
		                        			;
		                        		
		                        			Risk Factors
		                        			
		                        		
		                        	
4.Measurement of Opening and Closing Angles of Aortic Valve Prostheses In Vivo Using Dual-Source Computed Tomography: Comparison with Those of Manufacturers' in 10 Different Types.
Young Joo SUH ; Young Jin KIM ; Yoo Jin HONG ; Hye Jeong LEE ; Jin HUR ; Dong Jin IM ; Yun Jung KIM ; Byoung Wook CHOI
Korean Journal of Radiology 2015;16(5):1012-1023
		                        		
		                        			
		                        			OBJECTIVE: The aims of this study were to compare opening and closing angles of normally functioning mechanical aortic valves measured on dual-source computed tomography (CT) with the manufacturers' values and to compare CT-measured opening angles according to valve function. MATERIALS AND METHODS: A total of 140 patients with 10 different types of mechanical aortic valves, who underwent dual-source cardiac CT, were included. Opening and closing angles were measured on CT images. Agreement between angles in normally functioning valves and the manufacturer values was assessed using the interclass coefficient and the Bland-Altman method. CT-measured opening angles were compared between normal functioning valves and suspected dysfunctioning valves. RESULTS: The CT-measured opening angles of normally functioning valves and manufacturers' values showed excellent agreement for seven valve types (intraclass coefficient [ICC], 0.977; 95% confidence interval [CI], 0.962-0.987). The mean differences in opening angles between the CT measurements and the manufacturers' values were 1.2degrees in seven types of valves, 11.0degrees in On-X valves, and 15.5degrees in ATS valves. The manufacturers' closing angles and those measured by CT showed excellent agreement for all valve types (ICC, 0.953; 95% CI, 0.920-0.972). Among valves with suspected dysfunction, those with limitation of motion (LOM) and an increased pressure gradient (PG) had smaller opening angles than those with LOM only (p < 0.05). CONCLUSION: Dual-source cardiac CT accurately measures opening and closing angles in most types of mechanical aortic valves, compared with the manufacturers' values. Opening angles on CT differ according to the type of valve dysfunction and a decreased opening angle may suggest an elevated PG.
		                        		
		                        		
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Aortic Valve/*radiography
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Heart Valve Diseases/therapy
		                        			;
		                        		
		                        			*Heart Valve Prosthesis
		                        			;
		                        		
		                        			Heart Valve Prosthesis Implantation/*instrumentation
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Retrospective Studies
		                        			;
		                        		
		                        			Tomography, X-Ray Computed/methods
		                        			
		                        		
		                        	
5.Advantages and limitations of fetal cardiac intervention.
Hongyu DUAN ; Kaiyu ZHOU ; Yimin HUA
Chinese Journal of Pediatrics 2014;52(1):65-68
		                        		
		                        		
		                        		
		                        			Animals
		                        			;
		                        		
		                        			Aortic Valve
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Aortic Valve Stenosis
		                        			;
		                        		
		                        			congenital
		                        			;
		                        		
		                        			therapy
		                        			;
		                        		
		                        			Balloon Valvuloplasty
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Cardiac Surgical Procedures
		                        			;
		                        		
		                        			adverse effects
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Catheterization
		                        			;
		                        		
		                        			adverse effects
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Fetal Diseases
		                        			;
		                        		
		                        			therapy
		                        			;
		                        		
		                        			Fetal Heart
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Heart Defects, Congenital
		                        			;
		                        		
		                        			therapy
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Postoperative Complications
		                        			;
		                        		
		                        			epidemiology
		                        			;
		                        		
		                        			Pregnancy
		                        			;
		                        		
		                        			Pregnancy Trimester, Second
		                        			;
		                        		
		                        			Ultrasonography, Interventional
		                        			;
		                        		
		                        			methods
		                        			
		                        		
		                        	
6.Aortic valve replacement for quadricuspid aortic valve with regurgitation and stenosis in a renal transplant recipient.
Junsheng MU ; Xianshuai LI ; Jianqun ZHANG ; Ping BO ;
Chinese Medical Journal 2014;127(16):3033-3033
		                        		
		                        		
		                        		
		                        			Aged
		                        			;
		                        		
		                        			Aortic Valve
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Cyclosporine
		                        			;
		                        		
		                        			therapeutic use
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Heart Defects, Congenital
		                        			;
		                        		
		                        			drug therapy
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Heart Valve Diseases
		                        			;
		                        		
		                        			drug therapy
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Heart Valve Prosthesis
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Immunosuppressive Agents
		                        			;
		                        		
		                        			therapeutic use
		                        			;
		                        		
		                        			Kidney Transplantation
		                        			;
		                        		
		                        			Mycophenolic Acid
		                        			;
		                        		
		                        			analogs & derivatives
		                        			;
		                        		
		                        			therapeutic use
		                        			;
		                        		
		                        			Transplant Recipients
		                        			
		                        		
		                        	
7.Efficacy and experience in right ventricular pacing-percutaneous balloon aortic valvuloplasty.
Yongzhan SONG ; Junjie LI ; Guohong ZENG ; Zhiwei ZHANG ; Yufen LI ; Mingyang QIAN ; Wei PAN ; Shushui WANG
Chinese Journal of Pediatrics 2014;52(9):703-705
OBJECTIVETo evaluate the efficacy and experience in right ventricular pacing-percutaneous balloon aortic valvuloplasty (RVP-PBAV) for congenital aortic stenosis (AS).
METHODA total of sixteen children with AS accepted the treatment with RRVP-PBAV. The patients were at ages 6 months to 15 years, their median age was 5.4 years. Their body weight was between 8.5 and 59.0 kg, average (22.3 ± 16.5) kg. The gradient pressure across the aortic valve was measured for all the patients and aortic regurgitation was observed. The follow-up time ranged from 1 month to 5.5 years.
RESULTAll patients underwent RVP-PBAV successfully. The ratios of balloon/valve were 0.86 to 1.12. The gradient pressure varied from preoperative Δp = (96 ± 32) mmHg (1 mmHg = 0.133 kPa) to the immediate postoperative ΔP = (41 ± 26) mmHg, (P < 0.05). One case had postoperative restenosis, and 3 cases were complicated with bicuspid aortic valve deformity.
CONCLUSIONThe treatment with RVP-PBAV for congenital aortic stenosis is safe and reliable. Rapid ventricular pacing is a safe procedure to stabilize the balloon during balloon aortic valvuloplasty and may decrease the incidence of aortic insufficiency.
Adolescent ; Aorta ; Aortic Valve ; abnormalities ; Aortic Valve Insufficiency ; Aortic Valve Stenosis ; therapy ; Balloon Valvuloplasty ; methods ; Body Weight ; Cardiac Surgical Procedures ; Child ; Child, Preschool ; Follow-Up Studies ; Heart Defects, Congenital ; Heart Valve Diseases ; Heart Ventricles ; Humans ; Infant ; Postoperative Period ; Treatment Outcome ; Vascular Malformations
9.Aortic intramural hematoma after thrombolysis in a patient with acute massive pulmonary embolism.
Min Su KIM ; Kyu Seop KIM ; Il Soon JUNG ; Jae Hyeong PARK ; Jin Ok JEONG ; Si Wan CHOI ; In Whan SEONG
The Korean Journal of Internal Medicine 2013;28(5):619-621
		                        		
		                        			
		                        			No abstract available.
		                        		
		                        		
		                        		
		                        			Acute Disease
		                        			;
		                        		
		                        			Aged
		                        			;
		                        		
		                        			Anticoagulants/therapeutic use
		                        			;
		                        		
		                        			Antihypertensive Agents/therapeutic use
		                        			;
		                        		
		                        			Aortic Diseases/diagnosis/*etiology/physiopathology/therapy
		                        			;
		                        		
		                        			Aortography/methods
		                        			;
		                        		
		                        			Arterial Pressure
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Fibrinolytic Agents/*adverse effects
		                        			;
		                        		
		                        			Hematoma/diagnosis/*etiology/physiopathology/therapy
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Pulmonary Embolism/diagnosis/*drug therapy
		                        			;
		                        		
		                        			Recombinant Proteins/adverse effects
		                        			;
		                        		
		                        			Thrombolytic Therapy/*adverse effects
		                        			;
		                        		
		                        			Tissue Plasminogen Activator/*adverse effects
		                        			;
		                        		
		                        			Tomography, X-Ray Computed
		                        			;
		                        		
		                        			Treatment Outcome
		                        			;
		                        		
		                        			Vena Cava Filters
		                        			
		                        		
		                        	
10.A Case of Angiographic Embolization of Aortoenteric Fistula Caused by Endovascular Stent Grafting for an Abdominal Aortic Aneurysm.
Kwang Hun KO ; Seul Young KIM ; Il Soon JUNG ; Kyu Seop KIM ; Hee Seok MOON ; Jae Kyu SEONG ; Hyun Yong JEONG
The Korean Journal of Gastroenterology 2013;61(4):230-233
		                        		
		                        			
		                        			Aortoenteric fistula (AEF) developed after treatment for an abdominal aortic aneurysm (AAA) is a rare but usually fatal complication. We report a rare case of AEF bleeding after endovascular stent grafting for AAA which was managed angiographically. An 81-year-old man presented with hematochezia and acute abdominal pain for 1 day ago. Four years ago, an aortic stent was implanted in the infrarenal aorta for AAA. Endoscopies were performed to evaluate the hematochezia. Evidence of gastrointestinal bleeding was observed, but a clear bleeding point was not detected on upper endoscopy and colonoscopy. Contrast-enhanced computed tomography performed subsequently showed that the bleeding point was located in the fourth portion of the duodenum as an AEF caused by an inflammatory process in the stent-graft. Intra-arterial angiography showed a massive contrast leakage into the bowel via a small fistula from around the aortic stent graft site. Embolization was successfully performed by injecting a mixture of glue and lipiodol into the AEF tract. The patient was discharged with no evidence of gastrointestinal bleeding after the embolization.
		                        		
		                        		
		                        		
		                        			Aged, 80 and over
		                        			;
		                        		
		                        			Angiography
		                        			;
		                        		
		                        			Aortic Aneurysm, Abdominal/*therapy
		                        			;
		                        		
		                        			Aortic Diseases/*etiology/radiography/therapy
		                        			;
		                        		
		                        			Embolization, Therapeutic
		                        			;
		                        		
		                        			Endoscopy, Gastrointestinal
		                        			;
		                        		
		                        			Fistula/*etiology/radiography/therapy
		                        			;
		                        		
		                        			Gastrointestinal Hemorrhage/therapy
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Stents/*adverse effects
		                        			;
		                        		
		                        			Tomography, X-Ray Computed
		                        			
		                        		
		                        	
            
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