We describe an unusual case of hypoxic ischemic encephalopathy in a preterm female of 36 weeks who presented with status epilepticus and atypical abdominal myoclonus. The seizures were confirmed electrographically using video electroencephalography (EEG), while the abdominal myoclonus was demonstrated to be nonepileptic, as it had no EEG correlate. Other possible causes of neonatal seizures were excluded. The infant then responded to a gamut of antiseizure medications but the myoclonus persisted. To the best of our knowledge, this is the first report of atypical myoclonus in a preterm baby caused by hypoxic ischemic encephalopathy.

Human ; Hypoxic Ischemic Encephalopathy ; Hypoxia-ischemia, Brain ; Status Epilepticus ; Myoclonus ; Neonate ; Infant, Newborn

Background: Previous studies showed that B hepatitis prevalence in Vietnam was very high and the rate of mother-to-child transmission was range from 44.7% to 45.2%. Objectives: Study on the efficacies of the interventional methods with anti-HBV immunoglobulin and hepatitis B vaccination within 24 hours after birth for neonates in Hanoi. Subjects and method: This interventional study was carried out on 163 neonates of positive-HBsAg mothers who were admitted to Hanoi Obstetrical Hospital from 6/2005 to 3/2007. These neonates received anti-HBV immunoglobulin and hepatitis B vaccination within 24 hours after birth, then were followed up for 11 to 18 months. Results: Among these 163 neonates that received interventions, there were 135 neonates that underwent HBsAg tests after 11 to 18 months. The results showed that only one newborn baby had positive HBsAg (0.74%) and 134 neonates with non-HBV (99.26%). 81.5% of neonates had hepatitis B surface antibody that can protect against HBV. Conclusion: Early interventions with anti-HBV immunoglobulin and HBV vaccination were effective in preventing HBV for neonates of positive-HBsAg mothers.
anti-HBV immunoglobulin ; hepatitis B vaccination ; neonate