1.Study on Students’ Eating Behavior and Some Influencing Factors
Zolzaya B ; Altanchimeg D ; Ser-Od KH ; Khandmaa S ; Darambazar G
Mongolian Journal of Health Sciences 2025;85(1):96-101
Backround:
The university period is a unique phase in students’ lives, often marked by independent living, changes in
lifestyle, diet, sleep patterns, increased psychological stress, and the development of unhealthy behaviors. Among students, particularly those studying in the medical field, research on dietary habits and influencing factors is scarce in our
country, which serves as the rationale for this study.
Aim:
The aim of this study is to investigate the dietary habits of medical students and the factors influencing them, including sleep, impulsivity, depression, anxiety, and stress.
Materials and Methods:
A cross-sectional study was conducted among 358 students from years 1 to 6 across 7 schools of
the Mongolian National University of Medical Sciences (MNUMS). Data were collected using internationally standardized and validated questionnaires, including the Three-Factor Eating Questionnaire Revised-18 (TFEQ-R18), the Short
UPPS-P Impulsive Behavior Scale-20 (SUPPS-P-20), the Depression, Anxiety, and Stress Scale-21 (DASS-21), and the
Pittsburgh Sleep Quality Index (PSQI). Statistical analysis was performed using SPSS 25.0.
Results:
In terms of eating behavior, uncontrolled eating (UE) and cognitive restraint (CR) were similar between male
and female students, while emotional eating (EE) was more prevalent among male students. Students’ eating behaviors
were associated with body mass index (BMI). As BMI increased, levels of depression, anxiety, and stress also tended to
rise. Sensation-seeking and positive urgency were higher among female students. Overall, 83.5% of students had poor
sleep quality, which contributed to increased depression, anxiety, stress, and impulsivity. Psychological burden and impulsivity were independent of the field of study but decreased as students progressed through their academic years, while
sleep quality improved.
Conclusion
The dietary habits of medical students were similar across genders but varied by academic year and field
of study. Poor sleep quality, observed in 83.5% of students, was associated with increased depression, anxiety, stress,
and impulsivity. Psychological burden and impulsivity were unrelated to the field of study but decreased with advancing
academic years, alongside improved sleep quality. As BMI increased, cognitive restraint in eating behaviors decreased.
2. A study to determine actual daily consumption of drinking and residential water for households in Ulaanbaatar
Zolzaya D ; Suvd B ; Amgalan G ; Tsegmed S ; Bolor B ; Soyombo G ; Oyun-Erdene O ; Altangerel B ; Oyunchimeg D ; Enkhjargal A ; Bolormaa I ; Tsogtbaatar B
Mongolian Medical Sciences 2024;208(2):39-47
Introduction :
Water is a vital resource for human existence and is essential for daily food processing, preparation,
washing, hygiene, and sanitation. Furthermore, providing the population with safe drinking water is one
of the pressing problems of the world and some regions.
In recent years, population density and the scale of commercial and industrial activities, as well as clean
and dirty water consumption were increased in the capital city. As a result of these, ground and surface
water resources are becoming scarce and polluted.
Therefore, assessment of daily drinking and residential water consumption of Ulaanbaatar should be
determined to use drinking water properly in daily life and water loss. This study assessed the actual
amount of households’ daily water consumption.
Goal:
The purpose of this study is to determine the daily consumption of drinking water for households in ger
areas and apartments in Ulaanbaatar.
Materials and Method:
This study covers 30 households in ger areas and 15 apartment households, in Ulaanbaatar.
Household members performed 6-10 types of measurements every day, within 7 days. As a result of
these measurements, actual consumption of water quantity used for drinking and household purposes
was calculated. Statistical analysis was done by SPSS Version 21 to calculate the true probability of
difference between parameters.
Result:
67.9% of the households in the ger areas were 4-5 family members. The average daily household
consumption of drinking and domestic water were 68.3 ± 3.57 L (95% 61.3-75.3), the minimum
consumption was 12 L, and the maximum was 227 L. Average of the household water consumption
water was 97.6-108.9 liters during the weekends, and water consumption was statistically higher than
weekdays (p=0.001; p=0.01).
The water consumption of residential households with 3 family members accounted for the majority
(30.8%) in this study. The average daily consumption of drinking and domestic water was 297.67±19.7
liters. There was no statistically significant difference (p=0.96) in week. The average daily water
consumption including drinking and residential was 270.3-335.97 L.
The total daily drinking and residential water consumption per person was 15.57 L for households in ger areas and 90 L for apartment households. Calculating the daily water consumption of households in ger areas, 60.3% of it is used for laundry, washing dishes, food preparation, washing face and hands, and clothes, 31% for drinking, and 8.7% for outdoor water use. While apartment households, approximately 94.1%, were used for household and 5.9% for drinking purposes.
Research ethics approval :
This study was discussed at the meeting of the Academic Council of the National Center for Public
Health. In addition, this study was carried out according to the methods and methods discussed and
approved at the meeting of the Medical Ethics Control Committee of the Ministry of Health (Resolution
No. 08).
Conclusion
The total daily consumption of drinking and residential water per person were 15.57 litres for the
households in the ger areas and 90 litres for the apartment households. It implies that it does not exceed
the WHO recommendations
3.The clinical sign of children’s kidney and urinary tract petrification diseases and the result of ESWL
Baatartsogt S ; Amarjargal O ; Khurelbaatar U ; Oyunbileg U ; Gan-Erdene N ; Zolzaya G ; Enkhtur Sh ; Agiimaa D
Mongolian Journal of Obstetrics, Gynaecology and Pediatrics 2023;33(1):2401-2408
The clinical sign of children’s kidney and urinary tract petrification diseases and the result of eswl
Background: A substance exchange disorder where stones form in the kidney or urinary tract with a tendency toward inheritance is called urinary tract petrification disease. In many countries throughout the world, the incidence of urinary tract petrification disease is one to fifteen percent. Urinary tract permeability disease affects 7% of people under the age of 17. Due to the unique nature of the habitat, the incidence of urinary tract petrification disease is higher in India, Thailand, Scandinavian countries, and the Caucasian, Ural, Siberia, and Equator areas. However, the incidence of urinary tract petrification disease spread is two to three percent for children, but the reoccurance risk is 6.5–54 percent. In our country’s case, J. Horloo’s 1993 research indicates that 4.1 to 4.7 percent of kidney and urinary tract patients have urinary tract disease. During urinary tract disease, the common symptoms are abdominal pain, macro- and microhematuria, and kidney and renal bacterial infection. But in younger children, those symptoms are quite grim. In the last 15 years, mongolian’s urine’s oxalate stone’s volume increased by 5 times and mixed stones decreased by 2.5 times. The research of G. Erdenetsetseg’s 1990–1998 study on 305 children and the 2001–2003 study on 161 children indicate that the incidence of urinary tract disease is high between ages 1-3, and 65 percent of the stones consist of calcium oxalate. In 1980, German scientists invented the stone crushing technology using electrohydraulic shockwaves, which turned out to be a beneficial treatment for kidney surgery practice. The National Hospital for Maternal and Child Health's kidney surgery team had 17 surgeries in 2015, 19 surgeries in 2016, 24 surgeries in 2017, and 28 surgeries in 2018, and all of those surgeries were done and treated open. In the last 10 years of our country, children’s urinary tract petrification disease has gradually increased, but research on those diseases risks and factors is lacking. Also, the stone crushing method is necessary for our country’s children's treatment. That’s why we decided to do research on the risk factors of urinary tract disease and its relation to the stone crushing method.
Aim: Describe the features of children’s kidney and urinary tract petrification disease and study the stone crushing method’s results.
Materials and methods: The study was done between December of 2019 and April of 2022, with the assistance of NCMCH's children's kidney surgery team. Within the parameter of the first objective, within the group of cases of kidney and urinary tract disease, there were 13 children under the age of 17. The research study was conducted cross sectional. The research results were processed by the SPSS 25 program. On the seventh meeting of the health ministry, we got the acceptance of a research patent with the assistance of EHEMUT.
Results: The research group consisted of 13 children ages 0–17. The average age of participants was 10.6+-4.2.74. 4 percent of it consisted of men. The research of symptoms showed that back pain n = 13 (100), right side abdominal pain n = 13 (100), disurie n = 3 (23.1), mouth drying n = 2 (15.4), nausea n = 3 (23.1), urine with blood n = 10 (76.9), urine with smell n = 9 (69.2). The position of the stone consisted of 8 (61.5) in the kidney cup, 8 in the kidney cradle. Showing it in which kidney showed that 8 (61.5) were in the right kidney, 3 (23.1) in the left kidney, and 2 (15.4) in both kidneys. The density of the stones was n = 265.8+ 41.9 on average. Kidney stone coming out time was measured by Caplan-Myer’s survivability scale. The stones on the right side of the kidney came out within 14 days on average, while the left and both-sided kidney stones came out within 30 days.
Conclusions:
1. Showing the number of stones and locations indicates that 8 (61.5) were in the right kidney, 3 (23.1) in the left kidney, and 2 (15.4) in both kidneys.
2. The results of Caplan-Meyer's scale indicate that kidney stones within the right kidney came out within 14 days, and left- or both-sided stones came out within 30 days.
4.The effects of Particulate matter (PМ2.5) pollutants on cancer cells in in vitro model
Baljinnyam T ; Bilguun E ; Batchimeg B ; Zolzaya D ; Lkhaasuren N ; Oyungerel G ; Munkhtsetseg B ; Khaliun M ; Khulan U ; Batkhishig M ; Uranbileg U ; Sonomdagva Ch ; Bilegtsaikhan Ts ; Munkhbayar S ; Munkhtuvshin N ; Erkhembulgan P
Mongolian Medical Sciences 2021;197(3):17-25
Introduction:
Air pollution has become one of the major problems in socio-economic and health
issues in Mongolia. Among the various hazards of particulate matter (PM) pollutants, microorganisms
in PM2.5 and PM10 are thought to be responsible for various allergies and for the spread of respiratory
diseases. Recent studies have shown that PM2.5 particles can cause chronic heart failure, heart
arrhythmias, and strokes, as well as lung damage, cirrhosis, inflammation, cancer, cardiovascular
disease, and metabolic disorders. Furthermore, some studies have concluded that PM2.5 particles
in the environment are a risk factor for gastrointestinal, liver, colon, and lung cancer as well as it
affects the growth and metastasis of various cancer cells caused by other factors. In our country, the
health effects of air pollution and the relationship between the pathogenesis of cancer research are
scarce. Therefore, the study of the effects of PM2.5 particles on cancer cell proliferation, migration
(metastasis) can provide a significant role for cancer treatment, diagnosis, and prevention.
Purpose:
Determining the effects of PM2.5 particles on cancer cell proliferation, migration (metastasis)
in in-vitro
Material and Methods:
A human liver cancer cell line (HepG2), human gastric cancer cell line (AGS)
were obtained from the central scientific research laboratory in the Institute of medical sciences.
HepG2, AGS cells were seeded at a concentration of 1*105 cells/mL in a culture flask and cultured
in RPMI-1640 medium supplemented with 10% FBS, 1% antibiotic mix (penicillin, streptomycin) in a
humidified atmosphere of 5% CO2 at 37 °C. The cytotoxic effect of PM 2.5 in AGS, HepG2 cells were
evaluated by MTT, CCK8 assays. AGS, HepG2 cells were incubated in 96 well plates for 24h then
treated with different concentrations (0, 5, 10, 25, 50 and 100 μg ) of Bayankhoshuu, Buhiin urguu,
and Zaisan samples for 24h, respectively.
Results:
Concentrations of 10, 25, and 50 μg/ml of samples collected from the Bukhiin urguu and
Zaisan in March increased HepG2 cell growth, while doses of 25, 50 μg/ml of samples collected from
Bayankhoshuu in March and December increased HepG2 cell growth. Therefore, concentrations of
25 and 50 μg/ml of samples collected from Bayankhoshuu in March increased AGS cell growth, while concentrations of 25, 100 and μg/ml of samples collected in December increased AGS cell growth.
However, no cytotoxic effect was observed in the sample collected from Zaisan in March, whereas
the PM2.5 sample enhanced AGS cell growth in dose dependent manner in December.(p <0.05)
Conclusion
High levels of heavy metals were detected in samples collected in December from
Bayankhoshuu, Bukhiin urguu and Zaisan of Ulaanbaatar. Concentration of 25 μg/ml of samples
collected from the Bukhiin urguu and Zaisan in March increased HepG2 cell growth. Concentrations
of 25 μg/ml of PM2.5 collected from three regions around Ulaanbaatar increased HepG2 and AGS
cell migration.
5.Involvement of Vitamin D in Immune system
Baljinnyam T ; Batchimeg B ; Zolzaya D ; Ganchimeg D ; Lkhaasuren N ; Oyungerel G ; Munkhtsetseg B ; Khaliun M ; Khulan U ; Bilguun E ; Batkhishig M ; Tulgaa L ; Bilegtsaikhan Ts ; Munkhbayar S ; Munkhtuvshin N ; Munkhbat B
Mongolian Medical Sciences 2020;192(2):51-59
Research of function of vitamin D on immune system has been studying since the study revealed
that vitamin D receptor is expressed on the surface of the immune cells. 1,2-dihydroxyvitamin
D3 [1,25(OH)2D], physiologically active form, can be generated through hydroxylation of
25-hydroxyvitamin D3 [25(OH)D], inactive form of vitamin D, in a liver, connecting with specific VDR
make biological action. Vitamin D make different biological actions depends on connecting with
different immunological cells. Some studies indicated that Vitamin D plays pivotal role in antibacterial
innate immune responses through regulating reaction of the main cells as macrophages and dendritic
cells. Moreover, calcitriol, the active form of vitamin D, is connected with VDRE, modulates the innate
immune response through directly inducing expression of catelicithin and β-defensin as antimicrobial
peptides, reducing secretion of IL-1b, IL-6, TNF-a, RANKL, COX-2 as proinflammatory cytokines and
increasing production of IL-10, an anti-inflammatory cytokine. Vitamin D plays in proliferation and
differentiation of T and B cells and regulates the activities of over 500 genes. Vitamin D differently
impacts on per se stages of T cells’ proliferation. Vitamin D indirectly mitigates the differentiation from
immature B cells to plasma B cells while it directly impacts on regulation of overloaded production of
antibodies in plasma B cells. In conclusion, vitamin D modulates the innate- and adaptive immune
response through regulation on activation of APCells, proliferation and differentiation of immune cells,
secretion of some antibacterial peptides.
Result Analysis
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