1.Biological Basis of Glycometabolism and Lipid Metabolism Disorder and the Application of Regulating-States-and-Removing-Turbidity Method
Hongye PENG ; Chunli LU ; Mo ZHAO ; Shuxia HUANG ; Ziwen ZHUO ; Wenliang LYU
Journal of Traditional Chinese Medicine 2024;65(21):2199-2204
Combining the knowledge of traditional Chinese medicine and modern medicine on glucolipid metabolism disorders, it is believed that the formation process of glycolipid metabolism disorders can be presented as five states "depression, phlegm-dampness, heat, blood stasis, and deficiency", and the turbid pathogens run through the whole process. Accordingly, the method of "regulating states and removing turbidity" is proposed, which is specifically the method of resolving depression and turbidity, dispelling phlegm-dampness and turbidity, clearing heat and turbidity, dispelling blood stasis and turbidity, and replenishing deficiency and removing turbidity. Combined with the biological basis of glycolipid metabolism disorder, through the analysis of the clinical application of each method and the related mechanism of action, it is clarified that the method of regulating states and resolving turbidity can play a role in improving glycolipid metabolism disorder by regulating lipid metabolism disorder, insulin resistance, bile acid metabolism abnormality, intestinal bacterial flora, and its metabolite abnormality and other mechanisms of action.
2.Qualitative Research on the Influencing Factors of the Transformation of Scientific and Technological Achievements in Public Hospitals from the Perspective
Ziwen XU ; Jiajie ZHAO ; Sanyuan HAO ; Dong XU ; Ren CHEN
Chinese Hospital Management 2024;44(11):1-6
Objective To clarify the bottlenecks in the technology transfer work of public hospitals in China,and try to propose work optimization strategies and suggestions from the perspectives of different stakeholders.Methods The relevant literature about the transformation of scientific and technological achievements in public hospitals was searched on CNKI,and inductively summarize the relevant concepts and categories through the three stages of grounded theory coding.Results Through the three stages of coding,85 initial concepts,29 categories,and 5 main categories were sorted out,and a model attributing the influencing factors of the transformation of scientific and technological achievements in public hospitals was constructed,involving five major entities:public hospitals,medi-cal staff,enterprises,government,and universities.Conclusion The work of transforming scientific and technologi-cal achievements in public hospitals involves multiple stakeholders.It can start from the standardized management of public hospitals,the technological breakthroughs of medical staff,the active leadership of the government,the pro-active integration of enterprises,and the talent cultivation of universities to achieve innovation in talent cultivation mechanisms,industry evaluation mechanisms,profit distribution mechanisms,and intelligent management mecha-nisms.
3.Research on Cognition and Demand of Scientific and Technological Achievements Transformation of Medi-cal Staff in Public Hospitals
Ziwen XU ; Jiajie ZHAO ; Sanyuan HAO ; Dong XU ; Ren CHEN
Chinese Hospital Management 2024;44(11):7-11
Objective Understanding the cognitive attitude,influencing factors,and demand elements of medical staff in public hospitals towards the transformation of scientific and technological achievements,and proposing coun-termeasures and suggestions to improve the transformation rate of scientific and technological achievements in pub-lic hospitals.Methods Based on a questionnaire survey of the cognition and needs for the transformation of scientific and technological achievements among medical staff in public hospitals,it investigates medical personnel from 12 public hospitals in Anhui Province.Data processing is conducted using descriptive analysis and moderated mediation effect analysis methods.Results The cognitive attitude is positively correlated with influencing factors(r=0.125,P<0.01),the degree of cognition is positively correlated with demand elements(r=0.599,P<0.01),and influencing factors are positively correlated with demand elements(r=0.336,P<0.01).The impact factors of medical staff in the process of scientific and technological achievement transformation play a partial mediating role between cognitive attitude and demand elements,and the technical title of medical staff has a moderating effect.Conclusion There are bottlenecks in the transformation of scientific and technological achievements by medical staff in public hospitals,in-cluding a weak awareness of transformation,limited transformation capabilities,disconnection between scientific re-search achievements and the market,and an unobvious collaborative effect of"government,education,medical care,production,and research".Public hospitals should improve supporting measures in aspects such as talent cultivation,management systems,professional training,and information construction.
4.Evaluation of Scientific and Technological Achievements Transformation in University Affiliated Hospitals Based on Entropy Weight TOPSIS Method and Rank Sum Ratio Method
Jiajie ZHAO ; Sanyuan HAO ; Ziwen XU ; Dong XU ; Ren CHEN
Chinese Hospital Management 2024;44(11):18-24
Objective To evaluate the transformation of scientific and technological achievements in 12 affiliated hospitals of a medical university in Anhui Province,and to provide suggestions for the transformation of scientific and technological achievements in affiliated hospitals of colleges and universities.Methods According to the collected data,entropy weight method was used to assign weights to the index system,and TOPSIS method and rank sum ratio method were used for comprehensive evaluation.Results Among theevaluation indicators,the top 3 weights are the total amount of incoming accounts converted by self-implementation(4.801%),the total amount of incoming accounts earned by cooperating with others(4.801%),and the number of R&D institutions,transfer institutions,and conversion service platforms jointly built with affiliated universities(4.779%).In the fuzzy joint results,the top three hospitals were A,C and G,and the bottom three hospitals were K,H and E.There are obvious differences among hospitals,and there are differences between directly affiliated hospitals and non-directly affiliated hospitals.Conclusion The affiliated hospitals of colleges and universities should explore a development path of the transformation of scientific and technological achievements with their own characteristics and make the transformation from the actual situation.Transform the achievements into the discipline construction,deepen and expand the scientific research advantages;construct transformation consciousness raising system,and promote action with consciousness raising;colleges and universities lead the integration of medical industry to build a new ecology of medical production,study and research.
5.Neonatal in-hospital outcomes and follow-up in pregnancies with aortic dissection
Ziwen ZHAO ; Yun DONG ; Tieying ZHANG ; Xingkun LI ; Guiying LIU
Chinese Journal of Applied Clinical Pediatrics 2024;39(9):655-659
Objective:To explore the short-term and long-term effects of pregnancy with aortic dissection (AD) on newborns.Methods:In this retrospective cohort study, 31 live births of pregnant women with AD admitted to Beijing Anzhen Hospital, Capital Medical University from June 2010 to June 2022 were selected as the AD group.Among them, 19 preterm births were in the preterm AD group.Additionally, 100 neonates delivered by pregnant women without pregnancy complications were selected as the normal control group, and 50 preterm infants delivered by pregnant women without pregnancy complications were selected as the preterm control group during the same period.The differences between the AD group and the normal control group, and between the preterm AD group and the preterm control group were compared using the independent samples t-test, Chi-square test, and Fisher′s exact test.Patients in the AD group were followed up for 5 years. Results:(1) The incidence rates of small for gestational age (SGA) (12.90% vs. 1.00%), neonatal respiratory distress syndrome (NRDS) (16.13% vs. 2.00%), digestive tract hemorrhage (16.13% vs. 1.00%), nervous system disease (16.13% vs. 1.00%), multiple organ dysfunction syndrome (MODS) (12.90% vs. 0), premature infant (61.29% vs. 5.00%), asphyxia (35.48% vs. 1.00%), cardiopulmonary resuscitation (64.52% vs. 1.00%), respiratory support (38.71% vs. 2.00%), transfer to the department of pediatrics within 24 hours of birth (90.32% vs. 13.00%), caesarean section (100% vs. 25.00%), and low birth weight infant (38.71% vs. 2.00%) in the AD group were significantly higher than those in the normal control group, while the gestational age[(34.90±2.80) weeks vs. (38.87±1.50) weeks], length [(45.65±3.56) cm vs. (50.17±0.81) cm], and weight [(2 456.77±634.02) g vs. (3 383.90±413.05) g] were significantly less than those in the normal control group, and the differences were statistically significant (all P<0.05).(2) The gestational age [(33.26±2.31) weeks vs. (34.80±1.29) weeks], length [(43.89±3.36) cm vs. (46.64±2.89) cm], and weight [(2 158.95±558.92) g vs. (2 418.20±431.20) g] in the preterm AD group were less than those in the preterm control group, while the incidence rates of NRDS (26.32% vs. 4.00%), digestive tract hemorrhage (21.05% vs. 4.00%), nervous system disease (26.32% vs. 6.00%), MODS (21.05% vs. 2.00%), caesarean section (100% vs. 52.00%), cardiopulmonary resuscitation (73.68% vs. 8.00%), respiratory support (63.16% vs. 10.00%), and asphyxia (47.37% vs. 2.00%) were significantly higher than those in the preterm control group, and the differences were statistically significant (all P<0.05).(3) Twenty-seven cases in the AD group survived, and 4 cases were lost to follow-up.Among them, 9 cases had abnormal physical development, 3 cases had eye disease, and 1 case was mentally retarded.None of them underwent genetic detection. Conclusions:Neonates born to mothers with AD in pregnancy have poor physical development, high incidence of complications, and reduced quality of life, and need long-term monitoring and follow-up in their growth and development.
6.Qualitative Research on the Influencing Factors of the Transformation of Scientific and Technological Achievements in Public Hospitals from the Perspective
Ziwen XU ; Jiajie ZHAO ; Sanyuan HAO ; Dong XU ; Ren CHEN
Chinese Hospital Management 2024;44(11):1-6
Objective To clarify the bottlenecks in the technology transfer work of public hospitals in China,and try to propose work optimization strategies and suggestions from the perspectives of different stakeholders.Methods The relevant literature about the transformation of scientific and technological achievements in public hospitals was searched on CNKI,and inductively summarize the relevant concepts and categories through the three stages of grounded theory coding.Results Through the three stages of coding,85 initial concepts,29 categories,and 5 main categories were sorted out,and a model attributing the influencing factors of the transformation of scientific and technological achievements in public hospitals was constructed,involving five major entities:public hospitals,medi-cal staff,enterprises,government,and universities.Conclusion The work of transforming scientific and technologi-cal achievements in public hospitals involves multiple stakeholders.It can start from the standardized management of public hospitals,the technological breakthroughs of medical staff,the active leadership of the government,the pro-active integration of enterprises,and the talent cultivation of universities to achieve innovation in talent cultivation mechanisms,industry evaluation mechanisms,profit distribution mechanisms,and intelligent management mecha-nisms.
7.Research on Cognition and Demand of Scientific and Technological Achievements Transformation of Medi-cal Staff in Public Hospitals
Ziwen XU ; Jiajie ZHAO ; Sanyuan HAO ; Dong XU ; Ren CHEN
Chinese Hospital Management 2024;44(11):7-11
Objective Understanding the cognitive attitude,influencing factors,and demand elements of medical staff in public hospitals towards the transformation of scientific and technological achievements,and proposing coun-termeasures and suggestions to improve the transformation rate of scientific and technological achievements in pub-lic hospitals.Methods Based on a questionnaire survey of the cognition and needs for the transformation of scientific and technological achievements among medical staff in public hospitals,it investigates medical personnel from 12 public hospitals in Anhui Province.Data processing is conducted using descriptive analysis and moderated mediation effect analysis methods.Results The cognitive attitude is positively correlated with influencing factors(r=0.125,P<0.01),the degree of cognition is positively correlated with demand elements(r=0.599,P<0.01),and influencing factors are positively correlated with demand elements(r=0.336,P<0.01).The impact factors of medical staff in the process of scientific and technological achievement transformation play a partial mediating role between cognitive attitude and demand elements,and the technical title of medical staff has a moderating effect.Conclusion There are bottlenecks in the transformation of scientific and technological achievements by medical staff in public hospitals,in-cluding a weak awareness of transformation,limited transformation capabilities,disconnection between scientific re-search achievements and the market,and an unobvious collaborative effect of"government,education,medical care,production,and research".Public hospitals should improve supporting measures in aspects such as talent cultivation,management systems,professional training,and information construction.
8.Evaluation of Scientific and Technological Achievements Transformation in University Affiliated Hospitals Based on Entropy Weight TOPSIS Method and Rank Sum Ratio Method
Jiajie ZHAO ; Sanyuan HAO ; Ziwen XU ; Dong XU ; Ren CHEN
Chinese Hospital Management 2024;44(11):18-24
Objective To evaluate the transformation of scientific and technological achievements in 12 affiliated hospitals of a medical university in Anhui Province,and to provide suggestions for the transformation of scientific and technological achievements in affiliated hospitals of colleges and universities.Methods According to the collected data,entropy weight method was used to assign weights to the index system,and TOPSIS method and rank sum ratio method were used for comprehensive evaluation.Results Among theevaluation indicators,the top 3 weights are the total amount of incoming accounts converted by self-implementation(4.801%),the total amount of incoming accounts earned by cooperating with others(4.801%),and the number of R&D institutions,transfer institutions,and conversion service platforms jointly built with affiliated universities(4.779%).In the fuzzy joint results,the top three hospitals were A,C and G,and the bottom three hospitals were K,H and E.There are obvious differences among hospitals,and there are differences between directly affiliated hospitals and non-directly affiliated hospitals.Conclusion The affiliated hospitals of colleges and universities should explore a development path of the transformation of scientific and technological achievements with their own characteristics and make the transformation from the actual situation.Transform the achievements into the discipline construction,deepen and expand the scientific research advantages;construct transformation consciousness raising system,and promote action with consciousness raising;colleges and universities lead the integration of medical industry to build a new ecology of medical production,study and research.
9.Qualitative Research on the Influencing Factors of the Transformation of Scientific and Technological Achievements in Public Hospitals from the Perspective
Ziwen XU ; Jiajie ZHAO ; Sanyuan HAO ; Dong XU ; Ren CHEN
Chinese Hospital Management 2024;44(11):1-6
Objective To clarify the bottlenecks in the technology transfer work of public hospitals in China,and try to propose work optimization strategies and suggestions from the perspectives of different stakeholders.Methods The relevant literature about the transformation of scientific and technological achievements in public hospitals was searched on CNKI,and inductively summarize the relevant concepts and categories through the three stages of grounded theory coding.Results Through the three stages of coding,85 initial concepts,29 categories,and 5 main categories were sorted out,and a model attributing the influencing factors of the transformation of scientific and technological achievements in public hospitals was constructed,involving five major entities:public hospitals,medi-cal staff,enterprises,government,and universities.Conclusion The work of transforming scientific and technologi-cal achievements in public hospitals involves multiple stakeholders.It can start from the standardized management of public hospitals,the technological breakthroughs of medical staff,the active leadership of the government,the pro-active integration of enterprises,and the talent cultivation of universities to achieve innovation in talent cultivation mechanisms,industry evaluation mechanisms,profit distribution mechanisms,and intelligent management mecha-nisms.
10.Research on Cognition and Demand of Scientific and Technological Achievements Transformation of Medi-cal Staff in Public Hospitals
Ziwen XU ; Jiajie ZHAO ; Sanyuan HAO ; Dong XU ; Ren CHEN
Chinese Hospital Management 2024;44(11):7-11
Objective Understanding the cognitive attitude,influencing factors,and demand elements of medical staff in public hospitals towards the transformation of scientific and technological achievements,and proposing coun-termeasures and suggestions to improve the transformation rate of scientific and technological achievements in pub-lic hospitals.Methods Based on a questionnaire survey of the cognition and needs for the transformation of scientific and technological achievements among medical staff in public hospitals,it investigates medical personnel from 12 public hospitals in Anhui Province.Data processing is conducted using descriptive analysis and moderated mediation effect analysis methods.Results The cognitive attitude is positively correlated with influencing factors(r=0.125,P<0.01),the degree of cognition is positively correlated with demand elements(r=0.599,P<0.01),and influencing factors are positively correlated with demand elements(r=0.336,P<0.01).The impact factors of medical staff in the process of scientific and technological achievement transformation play a partial mediating role between cognitive attitude and demand elements,and the technical title of medical staff has a moderating effect.Conclusion There are bottlenecks in the transformation of scientific and technological achievements by medical staff in public hospitals,in-cluding a weak awareness of transformation,limited transformation capabilities,disconnection between scientific re-search achievements and the market,and an unobvious collaborative effect of"government,education,medical care,production,and research".Public hospitals should improve supporting measures in aspects such as talent cultivation,management systems,professional training,and information construction.

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