1.Gongji classification and treatment strategies for lateral clavicle fractures
Jianhong WU ; Jingming DONG ; Zhihua HAN ; Zhongguo FU ; Ming XIANG ; Weidong NI ; Lei ZHANG ; Xiaoming WU
Chinese Journal of Orthopaedics 2022;42(4):220-227
		                        		
		                        			
		                        			Objective:To establish a new classification of lateral clavicle fractures and to evaluate its clinical value.Methods:The data of 67 patients with lateral clavicle fractures admitted from January 2016 to December 2020 were included. Thirty-seven cases were from Shanghai First People's Hospital, including 22 males and 15 females, with an average age of 49.1 years (22-78 years). Thirty cases were from the Second Upper Limb Ward of Tianjin Hospital of Tianjin, including 20 males and 10 females, with an average age of 47.6 years (19-76 years). The ligament injury was determined by measuring the coracoclavicular space on Zanca view X-ray and the distance between the fracture fragment on the inferior surface of the 3D-CT and the distal end of the clavicle. All patients were classified according to the new classification (based on the measurement on Zanca view X-ray and 3D-CT reconstruction, the relationship between the fracture and the coracoclavicular ligament footprint, coracoclavicular ligament injury, the injury of the acromioclavicular joint and the stability of the fracture), conservative treatment is preferable for stable fractures, and surgical treatment for unstable fractures. Three experienced orthopaedic surgeons and three radiologists independently observed the imaging data of 67 patients with distal clavicle fractures, determined the fracture type according to the new classification, and randomly reclassified after 4 weeks interval. Finally, 15 cases were randomly selected for internal control (2 junior orthopedic physicians), and the ICC value was used to assess the reliability. Results:The lateral clavicle fractures were divided into 5 types according to the Gongji classification. Type 1: isolated conical tubercle avulsion fracture, and the fracture line is located medial to the coracoid process; Type 2: complete involvement of the trapezoid & conical ligament at the clavicle insertion, and the fracture line extends to the middle of the clavicle, mean while the acromioclavicular joint is intact; Type 3: fracture fragments on the inferior surface involving the trapezoidal/conical ligament, respectively; Type 4: rupture of the conical ligament, and avulsion fracture of the trapezoid ligament; Type 5: conical ligament intact, and avulsion fracture of clavicle insertion of the trapezoid ligament. There were 18 cases of type 1, 4 cases of type 2, 8 cases of type 3, 32 cases of type 4, and 5 cases of type 5. The inter-observer and intra-observer agreement of all included cases was good (inter-group: first ICC=0.764, second ICC=0.778; intra-group: shoulder specialist ICC=0.782, radiologist ICC=0.750, internal control ICC=0.793). Types 1 and 2 fractures were fixed with anatomical plate and coracoid anchor. Type 3 and 4 fractures were fixed with clavicle hook plate and coracoid anchor. And type 5 underwent conservative treatment. At the last follow-up, all patients had no obvious shoulder joint instability and pain, and no internal fixation failure or fixation breakage was found. Conclusion:The Gongji classification has moderate reliability between observers and intra-observers, and the Gongji distal clavicle fracture classification has a good significance for evaluating the stability of the fracture and guiding the selection of the treatment.
		                        		
		                        		
		                        		
		                        	
2.Curative effects of Nice knot fixation on tuberosity healing in hemiarthroplasty for complex proximal humeral fractures
Mingtai MA ; Songlu ZENG ; Jiabao JU ; Yichong ZHANG ; Jianhai CHEN ; Dianying ZHANG ; Zhongguo FU
Chinese Journal of Orthopaedic Trauma 2022;24(2):127-131
		                        		
		                        			
		                        			Objective:To explore the curative effects of Nice knot fixation on tuberosity healing in hemiarthroplasty for complex proximal humeral fractures.Methods:A retrospective analysis was conducted of the eligible 32 complex proximal humeral fractures which had been treated at Department of Trauma and Orthopedics, Peking University People's Hospital between May 1, 2016 and May 1, 2019. Nice knot fixation was used to repair greater and lesser tuberosities in hemiarthroplasty for all the patients. There were 6 males and 26 females, aged from 60 to 90 years (mean, 74.9 years). By the Neer classification, there were 4 three-part fractures combined with dislocation, 20 four-part fractures, and 8 four-part fractures combined with dislocation. Shoulder joint X-rays were taken at postoperative 1, 2, 3, 6, and 12 months at the outpatient clinic to evaluate the patients' shoulder joint mobility, visual analog scale (VAS) pain score and Constant-Murley shoulder score. Tuberosity healing was assessed based on the X-rays and related complications were recorded.Results:The 32 patients received complete follow-up for 12 to 25 months (average, 17.82 months). At the 12-month follow-up, their shoulder flexion averaged 131.3° (from 80° to 155°), abduction 126.9° (from 80° to 155°), external rotation 48.4° (from 30° to 60°), internal rotation the L2 level, VAS pain score 0.9 (from 0 to 5), and Constant-Murley score 83.4 (from 58 to 96). The rate of patient satisfaction was 87.5%(28/32). Tuberosity-related complications were observed in 6 cases with an incidence of 18.8%. Complications like infection and prosthetic loosening were found in none of the patients.Conclusion:In hemiarthroplasty for complex proximal humeral fractures, application of Nice knot to fixate greater and lesser tuberosities can lead to rigid fixation, definite curative effects and a low incidence of tuberosity-related complications.
		                        		
		                        		
		                        		
		                        	
3. Expert consensus on emergency surgery management for traumatic orthopedics under prevention and control of novel coronavirus pneumonia
Jing LIU ; Hui LI ; Wu ZHOU ; Guohui LIU ; Yingze ZHANG ; Baoguo JIANG ; Peifu TANG ; Guodong LIU ; Xinbao WU ; Zhi YUAN ; Fang ZHOU ; Tianbing WANG ; Zhongguo FU ; Zhiyong HOU ; Jiacan SU ; Bin YU ; Zengwu SHAO ; Tian XIA ; Liming XIONG ; Yue FANG ; Guanglin WANG ; Peng LIN ; Yanxi CHEN ; Jiangdong NI ; Lei YANG ; Dongliang WANG ; Chengjian HE ; Ximing LIU ; Biao CHE ; Yaming LI ; Junwen WANG ; Ming CHEN ; Meng ZHAO ; Faqi CAO ; Yun SUN ; Bobin MI ; Mengfei LIU ; Yuan XIONG ; Hang XUE ; Liangcong HU ; Yiqiang HU ; Lang CHEN ; Chenchen YAN
Chinese Journal of Trauma 2020;36(2):111-116
		                        		
		                        			
		                        			 Since December 2019, novel coronavirus pneumonia (NCP) has been reported in Wuhan, Hubei Province, and spreads rapidly to all through Hubei Province and even to the whole country. The virus is 2019 novel coronavirus (2019-nCoV), never been seen previously in human, but all the population is generally susceptible. The virus spreads through many ways and is highly infectious, which brings great difficulties to the prevention and control of NCP. Based on the needs of orthopedic trauma patients for emergency surgery and review of the latest NCP diagnosis and treatment strategy and the latest principles and principles of evidence-based medicine in traumatic orthopedics, the authors put forward this expert consensus to systematically standardize the clinical pathway and protective measures of emergency surgery for orthopedic trauma patients during prevention and control of NCP and provide reference for the emergency surgical treatment of orthopedic trauma patients in hospitals at all levels. 
		                        		
		                        		
		                        		
		                        	
4.A preoperative risk scoring system for elderly patients with hip fracture
Mingtai MA ; Hao LU ; Peixun ZHANG ; Dianying ZHANG ; Zhongguo FU ; Baoguo JIANG
Chinese Journal of Orthopaedic Trauma 2019;21(7):553-557
		                        		
		                        			
		                        			Objective To verify the effectiveness of a self-designed preoperative risk scoring system for elderly patients with hip fracture.Methods A total of 286 elderly patients with hip fracture were included for this prospective study who had been admitted from February 1,2014 to February 1,2016 to Department of Trauma and Orthopedics,Peking University People's Hospital.They were divided into 5 groups according to their scores by our self-designed preoperative risk scoring system for elderly patients with hip fracture:0 to 10 points,11 to 20 points,21 to 30 points,31 to 40 points and above 41 points.Postoperative complications and deaths were recorded.The correlations between their preoperative scores and postoperative medical complications or death were analyzed to verify the effectiveness of the preoperative risk scoring system for elderly patients with hip fracture.Results The 286 patients scored 24.9 ± 11.0 (from 0 to 69) preoperatively.The femoral neck fractures scored 24.0±11.0 and femoral intertrochanteric fractures 26.3±10.8.The incidence of medical complications was 4.00% (1/25) in the 0 to 10 points group,4.17% (3/72) in the 11 to 20 points group,14.66% (17/116) in the 21 to 30 points group,23.53% (12/51) in the 31 to 40 points group and 50.00% (11/22) in the above 41 pints group.Conclusion As the incidence of postoperative medical complications in elderly patients with hip fracture is positively correlated with the scores by our self-designed preoperative risk scoring system for elderly patients with hip fracture,the preoperative risk scoring system can provide an effective prediction of surgical risks.
		                        		
		                        		
		                        		
		                        	
5.Modification of a preoperative risk scoring system for elder patients with hip fracture and its prediction of in-hospital mortality
Peixun ZHANG ; Wei ZHANG ; Mingtai MA ; Zhongguo FU ; Dianying ZHANG ; Baoguo JIANG
Chinese Journal of Orthopaedic Trauma 2019;21(8):680-686
		                        		
		                        			
		                        			Objective To evaluate the efficacy of a modified risk scoring system in predicting the mortality during hospitalization in the elderly patients undergoing hip fracture surgery.Methods At the first stage,we retrospectively analyzed the clinical data of 1,562 elderly patients with hip fracture who had been admitted to Department of Trauma and Orthopedics,Peking University People's Hospital from January 2010 to December 2014.A multi-factor risk-adjustment model for surgical risks was constructed by multi-variate logistic regression analysis to obtain a modified preoperative risk scoring system for elderly patients undergoing hip fracture.At the second stage,a cohort of 1,356 elderly patients with hip fracture from January 2015 to December 2018 was included for a prospective evaluation of the modified risk scoring system.The patients included were divided into 5 groups according to their scores:a very low risk group of 0 to 10 points,a low risk group of 11 to 20 points,a moderate risk group of 21 to 30 points,a high risk group of 31 to 40 points and a very high risk group of ≥41 points.The consistency between the scores and the actual outcomes of the patients was observed and the receiver operating characteristic curve (ROC) was drawn accordingly.Results The 1,356 cases included in the study scored 25.12 ± 10.30 points (from 0 to 67 points).The in-hospital mortality was 0% (0/96) in the very low risk group,0.23% (1/443) in the low risk group,0.49% (2/409) in the moderate risk group,2.16% (6/278) in the high risk group,and 5.38% (7/130) in the very high risk group.The area under the ROC curve was 0.825 (95% CI:0.728-0.921,P < 0.01).Conclusions As the in-hospital mortality is positively correlated with the scores of the modified preoperative risk scoring system for elderly patients undergoing hip fracture,the modified scoring system can be used to predict the in-hospital morbidity of the patients.The modified scoring system can be further verified and calibrated by multi-center clinical evaluation.
		                        		
		                        		
		                        		
		                        	
6.Suture-button technique for acute Lisfranc injury
Hao LU ; Hailin XU ; Yu DANG ; Yusong YUAN ; Zhongguo FU ; Dianying ZHANG ; Baoguo JIANG
Chinese Journal of Orthopaedic Trauma 2019;21(4):310-313
		                        		
		                        			
		                        			Objective To observe operative outcomes of suture-button technique for acute Lisfranc injury.Methods A retrospective observation was conducted of the 11 patients who had been operatively treated with suture-button technique and plate fixation for acute Lisfranc injury from January 2015 to December 2016.They were 8 men and 3 women,aged from 22 to 54 years(mean,32.1 years).By the Myerson classification for the injury,there were 9 cases of type B2 and 2 cases of type Cl;by the Chiodo classification,there were 7 cases of middle column injury,2 cases of injury to middle and lateral columns and 2 cases of injury to medial and middle columns.Their scores on the visual analogue scale(VAS),mid-foot scores of American Orthopedic Foot and Ankle Society(AOFAS),bone union and complications were observed post-operatively.Results Follow-ups for this cohort lasted for 14 to 34 months(mean,20.5 months).Follow-ups revealed that their VAS scores for the affected foot averaged 0.6(from 0 to 2),significantly higher than those for the nomal foot(Z=2.070,P=0.038).Their AOFAS scores averaged 95.2(from 87 to 100),significantly lowerer than those for the nomal foot(Z=2.121,P=0.034).All fractures were united well.Conclusion Suture-button technique can lead to satisfactory outcomes for acute Lisfranc injury.
		                        		
		                        		
		                        		
		                        	
7.Formulating a preoperative risk scoring system for elderly patients with hip fracture
Mingtai MA ; Hao LU ; Peixun ZHANG ; Dianying ZHANG ; Zhongguo FU ; Baoguo JIANG
Chinese Journal of Orthopaedic Trauma 2018;20(12):1031-1037
		                        		
		                        			
		                        			Objective To establish a preoperative risk scoring system for elderly patients with hip fracture on the basis of investigation into the factors influencing their mortality during hospitalization. Methods The data were collected from the database of hospitalization summary reports ( HSR ) of Beijing Public Health Commission concerning the 14, 577 patients who had been 55 years old or older and hospitalized for hip fracture from January 1, 2006 throughout December 31, 2010 at the 35 top-rank hospitals in Beijing. They were divided into a surgery group and a non-surgery group. Two multivariable risk-adjustment models were established for the 2 groups on the basis of an investigation into the factors influencing their mor-tality during hospitalization. Finally a preoperative risk scoring system for elderly patients with hip frac-ture was formulated according to the valuation of the least common multiples of β coefficients of the risk factors.Results Besides senior age and male gender, 10 different comorbidities were independently associated with in-hospital mortality, particularly pulmonary embolism, respiratory failure, renal failure and diabetes. The risk for inpatient mortality associated with a specific comorbidity was relatively higher in the surgery group than in the non-surgery group. The risk-adjustment models based on the variables had better accuracy in predicting in-hospital mortality ( ROC=0.91 in surgery group versus ROC=0.85 in non-surgery group ). In our preoperative risk scoring system for elderly patients with hip fracture, 10 points were for an age of 65 to 74 years old, 14 points for an age of 75 to 84 years old, 18 points for an age beyond 85 years old, 4 points for male gender, 20 points for pulmonary embolism, 18 points for respiratory failure, 10 points for renal insufficiency, 8 points for diabetes, 8 points for heart failure, 7 points for malignant tumor, 7 points for lung infection, 7 points for disturbance of water, electrolyte and acid-base balance, 6 points for arrhythmia, and 6 points for cerebral infarction, totaling 119 points. Conclusions The primary risk factors for in-hospital mortality in the elderly patients with hip fracture seem to be senior age, male gender and 10 different comorbidi-ties. A preoperative risk scoring system has been successfully established for elderly patients with hip fracture.
		                        		
		                        		
		                        		
		                        	
8.Enhancing effects of Haishen-Xiyangshen-Gouqizi Koufuye on the immune function of immunocompromised mice
Shengcan ZOU ; Zhongguo FU ; Bing CAI
Journal of International Pharmaceutical Research 2017;44(6):556-560
		                        		
		                        			
		                        			Objective To evaluate the immunomodulatory effect of Haishen-Xiyangshen-Gouqizi Koufuye(HXGK),an oral liquid of healthy food product,on the immunocompromised mouse model. Methods The cytotoxicity was assayed by the MTT method using murine monocyte macrophagse Raw264.7 cells. The in vitro phagocytic activity of RAW264.7 cells was assayed by the colorimet-ric neutral red phagocytosis test. In the in vivo mouse test,animals were randomized into six groups,each with ten mice:the normal control,model control,positive control groups and three HXGK(5,10,and 20 ml/kg)test groups. The immunocompromised mouse model was created by the intraperitoneal injection of 40 mg/kg dexamethasone once every other day for a total of five times. After first time injection of dexamethasone,the normal control(without the dexamethasone injection)and model control groups were adminis-tered orally once a day with saline,the positive control group with 25 mg/kg levamisole,and the three test groups with 5,10 and 20 ml/kg HXGK,respectively,for a total of 21 days. Then the carbon particle clearance index,the spleen and thymus indices,and the leukocytes,lymphocytes,IgG and IgA in peripheral blood were measured respectively. Results Compared with the normal control, HXGK significantly enhanced the phagocytic index of RAW264.7 cells from 1.00 to 1.12(P<0.01)and 1.32(P<0.01)at the 100-and 20-fold diluted dosages,respectively,in the in vitro neutral red phagocytosis test. In the in vivo mouse test,compared with the model control group,HXGK at the doses of 5,10 and 20 ml/kg obviously increased the carbon particle clearance index about 1.8(P<0.01),1.5(P<0.05)and 1.7-fold(P<0.05)and improved the spleen index from 1.60 to 2.96(P<0.01),2.56(P<0.01)and 2.32(P<0.05),the thymus index from 1.31 to 1.46,1.59(P<0.05)and 1.71(P<0.05),respectively. Meanwhile,HXGH at the 5,10 and 20 ml/kg dosages also increased the leukocytes about 1.32,1.75(P<0.05)and 1.46 folds(P<0.05),the lymphocytes about 16 (P<0.01),20(P<0.01)and 19 folds(P<0.01),the IgG level about 19%,57%(P<0.01)and 64%(P<0.05),and the IgA lev-el about 65%(P<0.01),47%(P<0.05)and 44%(P<0.01),all in the peripheral blood respectively. Conclusion HXGH could significantly enhance the immune function of the immunocompromised mice.
		                        		
		                        		
		                        		
		                        	
9.Two posteromedial approaches in treatment of posterior pilon fractures of Klammer type Ⅲ
Hao LU ; Hailin XU ; Baoguo JIANG ; Zhongguo FU ; Dianying ZHANG
Chinese Journal of Orthopaedic Trauma 2017;19(12):1052-1055
		                        		
		                        			
		                        			Objective To observe operative results of 2 posteromedial approaches in the treatment of posterior pilon fractures of Klammer type Ⅲ.Methods From January 2015 to December 2016,19 patients with posterior pilon fracture (Klammer type Ⅲ) were treated via the posteromedial approach.They were 12 men and 7 women,aged from 21 to 61 years (mean,37.4 years).Straight posteromedial incision was used in 11 cases and curved posteromedial incision in the other 8 cases.The 2 groups were compared in terms of postoperative wound complication,infection,bone union,visual analogue scale (VAS) and American Orthopedic Foot and Ankle Society (AOFAS) scores.Results Follow-up ranged from 6 to 29 months (mean,11.8 months).All the fractures united after 6 to 15 months (mean,10.7 months).In the straight incision group,the VAS scores at the final follow-up ranged from 0 to 3 points,averaging 1.1 points;the AOFAS scores ranged from 83 to 100 points,averaging 90.8 points.In the curved incision group,the VAS scores at the final follow-up ranged from 0 to 3 points,averaging 1.3 points;the AOFAS scores ranged from 80 to 100 points,averaging 90.1 points.In one case in the curved incision group,the posteromedial wound failed to heal but scar healing was achieved after dressing change for 4 months.Conclusion The posteromedial approach,whether straight or curved,can provide good exposure for posterior pilon fractures of Klammer type Ⅲ,which is conductive to reduction and fixation of the fracture.
		                        		
		                        		
		                        		
		                        	
10.Two minimally invasive surgical treatments for Achilles tendon rupture: Achillon versus sponge forceps
Ming YANG ; Xiaomeng ZHANG ; Dianying ZHANG ; Zhongguo FU ; Hao LU ; Hailin XU
Chinese Journal of Orthopaedic Trauma 2016;18(3):192-196
		                        		
		                        			
		                        			Objective To compare 2 mini-invasive surgical treatments,Achillon versus sponge forceps,for acute Achilles tendon rupture.Methods Between December 2010 and January 2015,35 patients with acute Achilles tendon rupture were treated at our department.They were 32 males and 3 females,with an average age of 36.4 years (range,21 to 64 years).The interval between injury and operation was 1 to 13 days (average,3.2 days).Sixteen of them were treated by Achillon while 19 by sponge forceps.The 2 groups were compatible with no significant differences in general clinical data (P > 0.05).Rehabilitation was carried out 4 weeks after immobilization with brace.American Orthopaedic Foot and Ankle Society (AOFAS) ankle-hindfoot scoring system was used to evaluate the function of the affected foot at the last follow-up.The 2 groups were compared in terms of surgery time,hospital stay,AOFAS score,decrease in leg circumference,complications and rerupture rate.Results All the patients were followed up for an average of 9.6 months (from 6 to 19 months).There were no significant differences between the Achillon and sponge forceps groups regarding average AOFAS score (91.8 ± 4.4 versus 93.2 ± 5.8),surgery time (38.3 ± 13.2 min versus 42.5 ± 9.8 min),hospital stay (3.9 ± 1.5 d versus 4.1 ± 1.6 d),or decrease in leg circumference (2.1 ±0.5 cm versus 2.3 ± 0.3 cm) (P > 0.05).No re-ruptures or sural nerve lesion was observed in either group.One case of delayed wound healing occurred in each group.Conclusions Both Achillon and sponge forceps can lead to limited complications and a very low rate of re-rupture in surgical treatment of acute Achilles tendon rupture.Compared with the Achillon technique,sponge forceps may have the advantages of simplicity and lower cost.
		                        		
		                        		
		                        		
		                        	
            
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