1.Implicit and explicit measures of loyalty assessment among military cadets
Xuerong LIU ; Yu ZHAN ; Wei LI ; Libin ZHANG ; Mengxue ZHAO ; Xinyan GAO ; Zhiyi CHEN ; Zhengzhi FENG
Journal of Army Medical University 2024;46(3):203-208
		                        		
		                        			
		                        			Objective To explore the relevant relationship and specificity between the implicit and explicit loyalty of military cadets in order to provide a theoretical basis and objective indicators for a more comprehensive and objective assessment for individual loyalty.Methods E-Prime 2.0,a classic implicit association paradigm was employed to construct an implicit association loyalty test for 64 military cadets.Simultaneously,an explicit loyalty measurement was conducted using the Chinese Military Personnel Loyalty Scale.Results ① Significant implicit effect was observed in the loyalty assessment of military cadets,indicating a general tendency to perceive higher levels of personal loyalty and lower levels of loyalty to external entities.② Explicit loyalty assessment revealed that the participants had the highest loyalty score towards the Party,the Nation,and the People(4.79±0.34),followed by the loyalty score to their profession(4.38±0.53),and the relatively lower loyalty score towards the unit and leaders(4.03±0.83).Among the 3 dimensions of loyalty,the normative loyalty score ranked highest,while continuance loyalty score took lower.③ There were no correlations among the scores of loyalty to the Party,the Nation,and the People(r=-0.030,P=0.823),to the profession(r=-0.047,P=0.728),to the unit(r=0.050,P=0.710),or to the leaders(r=0.043,P=0.749).Conclusion The implicit effect in the loyalty assessment is significant in military cadets,and there is no significant correlation between explicit and implicit loyalty measurements.Thus,we cannot rely solely on explicit measurements to assess their loyalty attitudes.
		                        		
		                        		
		                        		
		                        	
2.Social adaptation in the association between attitude towards parents with academic anxiety among middle school students
LI Zhanghong, ZHOU Yaning, YANG Tianye, ZHU Beibei, FENG Zhengzhi
Chinese Journal of School Health 2024;45(12):1738-1742
		                        		
		                        			Objective:
		                        			To understand the social adaptation in the association between attitude towards parents with academic anxiety among middle school students in Chongqing, so as to provide a basis and thinking method for theoretical framework of family education and youth development.
		                        		
		                        			Methods:
		                        			Convenient and clustering sampling method was used to select 34 097 middle school students aged 13-18 years during September to November 2023. All the participants were investigated with self designed questionnaire, Social Adaptability Scale and Mental Health Test. The mediating effect of social adaptability in the relationship between students  attitudes towards their parents academic anxiety was evaluated by using Logistic regression analysis and structural equation model.
		                        		
		                        			Results:
		                        			The proportion of high school students in Chongqing with academic anxiety was 48.80%. Academic anxiety differed significantly by sex, academic grade, attitude towards parents, and social adaptability ( χ 2=948.45, 173.92, 537.51, 4 770.04,  P < 0.01). The results of Logistic regression analysis showed that positive attitudes towards parents were positively correlated with moderate academic anxiety ( OR=1.13, 95%CI =1.08-1.18) and high academic anxiety ( OR=1.14, 95%CI =1.09-1.19) ( P < 0.05 ). The results of the mediation effect analysis showed that positive attitude of middle school students towards their parents negatively predicted academic anxiety ( β= -0.12 , P <0.01), but when social adaptation ability was used as a control variable, the original negative relationship between the positive attitude towards parents and academic anxiety of middle school students changed  ( β=0.02, P <0.01), and social adaptation ability played a masking effect in the relationship. The social adaptation ability of middle school students played a mediating role in the relationship between their positive attitudes towards their parents and academic anxiety, with a mediating effect of -0.63.
		                        		
		                        			Conclusions
		                        			The attitude of middle school students towards their parents will directly affect academic anxiety, and also have an indirect impact on academic anxiety through social adaptability, but there is a cover effect. Pay more attention to family education and actively focus on students  social adaptability can contribute to improve the mental health level of adolescents.
		                        		
		                        		
		                        		
		                        	
3.Effect of military operation types on dual factors of mental health in Chinese veterans:mediating role of psychological quality
Yuanyuan LI ; Yan WANG ; Xingya LIAO ; Xiaoling ZHANG ; Ke XIONG ; Shujuan SUN ; Zhengzhi FENG
Journal of Army Medical University 2024;46(14):1600-1608
		                        		
		                        			
		                        			Objective To explore the effects of military operation types on the mental health of Chinese veterans and the mediating role of psychological quality based on a dual-factor model of mental health.Methods Cross-sectional study design was adopted in this study.Self-designed demographic information questionnaire,patient health questionnaire depression module-9 item(PHQ-9),general anxiety disorder-7(GAD-7),satisfaction with life scale and psychological quality questionnaire were used to survey on 3 027 Chinese veterans.Results ① Compared to the one-factor model and the two-factor models with other indicators,the dual-factor model of mental health,with anxiety symptoms as a negative indicator and life satisfaction as a positive indicator,fitted better(Chi-square/df=8.927,GFI=0.974,AGFI=0.962,RMSEA=0.051,NNFI=0.985,IFI=0.988,CFI=0.988).②Taking the subjects who did not participate in war/non-war military operations as the reference,psychological quality showed significant relatively mediating effects between war and life satisfaction,and between war and anxiety symptoms(P<0.05),while no such significances were observed in the corresponding ones for non-war military operations.③ War could decrease veterans'life satisfaction through full mediation of cognitive,adaptive and personality dimensions of psychological quality,and increase anxiety symptoms through partial mediation of the personality dimension of psychological quality.Conclusion The dual-factor model of mental health is applicable to Chinese veteran population,and psychological quality plays a mediating role between war and mental health.
		                        		
		                        		
		                        		
		                        	
4.Characteristics and influencing factors for family resilience among Chinese Army personnel
Shujuan SUN ; Dongxia LIU ; Pingmei LI ; Chengjun DU ; Ke XIONG ; Mengxue ZHAO ; Zhengzhi FENG
Journal of Army Medical University 2024;46(14):1609-1617
		                        		
		                        			
		                        			Objective To explore the characteristics and influencing factors of family resilience among Chinese PLA Army personnel.Methods A total of 8 094 military personnel subjected with cluster sampling were surveyed with family resilience scale(FRS)and self-designed questionnaire for basic information on military families.Independent sample t test,one-way analysis of variance and step-up regression analysis were employed to analyze the family resilience.Results ① The results of demographic variable analysis showed that there were significant differences in family resilience among the personnel with different marital status,from one-child family or not,birth in rural/urban areas,personnel category,age and education level(P<0.05).② Family factors analysis indicated that different family structure,different family relationships,family rearing styles,recent separation from family members,and frequency of contacting family members had certain effects on family resilience(P<0.05).③ When family relationship,family rearing styles,frequency of contacting family members,birth place,recent separation from family,personnel category,from one-child family,and education level entered the regression equation,the resilience level of army personnel'families was increased by 8.197 for every 1 unit increase in family relationship,and the level of family resilience was increased by 4.688 for every 1 unit increase in family contact frequency(F=202.168,P<0.05).Conclusion The overall level of family resilience of army personnel is good.The risk factors for family resilience are recent separation from their families for ≥1 year,officers,not from only-children family,and the protective factors are harmonious relationship with their families,democratic family rearing style,contacting with their families weekly,urban birth,and bachelor degree or above.
		                        		
		                        		
		                        		
		                        	
5.The suppression of cervical cancer ferroptosis by macrophages: The attenuation of ALOX15 in cancer cells by macrophages-derived exosomes.
Yanlin LUO ; Yibing CHEN ; Huan JIN ; Benxin HOU ; Hongsheng LI ; Xiang LI ; Lingfeng LIU ; Yuan ZHOU ; Yonghua LI ; Yong Sang SONG ; Quentin LIU ; Zhengzhi ZOU
Acta Pharmaceutica Sinica B 2023;13(6):2645-2662
		                        		
		                        			
		                        			Induction of cancer cell ferroptosis has been proposed as a potential treatment in several cancer types. Tumor-associated macrophages (TAMs) play a key role in promoting tumor malignant progression and therapy resistance. However, the roles and mechanisms of TAMs in regulating tumor ferroptosis is still unexplored and remains enigmatic. This study shows ferroptosis inducers has shown therapeutic outcomes in cervical cancer in vitro and in vivo. TAMs have been found to suppress cervical cancer cells ferroptosis. Mechanistically, macrophage-derived miRNA-660-5p packaged into exosomes are transported into cancer cells. In cancer cells, miRNA-660-5p attenuates ALOX15 expression to inhibit ferroptosis. Moreover, the upregulation of miRNA-660-5p in macrophages depends on autocrine IL4/IL13-activated STAT6 pathway. Importantly, in clinical cervical cancer cases, ALOX15 is negatively associated with macrophages infiltration, which also raises the possibility that macrophages reduce ALOX15 levels in cervical cancer. Moreover, both univariate and multivariate Cox analyses show ALOX15 expression is independent prognostic factor and positively associated with good prognosis in cervical cancer. Altogether, this study reveals the potential utility of targeting TAMs in ferroptosis-based treatment and ALOX15 as prognosis indicators for cervical cancer.
		                        		
		                        		
		                        		
		                        	
6.Perturbations in gastrointestinal tract microbiota composition and function in individuals with yellow-greasy tongue coating
LIU Zhanyan ; LI Zhiyue ; ZHU Guanbao ; LIU Yaqian ; PENG Qinghua ; WU Zhengzhi
Digital Chinese Medicine 2023;6(2):160-169
		                        		
		                        			
		                        			【Objective】  To study the composition and function of tongue coating (TC) and gastrointestinal
tract (GIT) microbiota in participants with yellow-greasy tongue coating (YGTC), and to explore the representative metabolite markers and pathways in this group.
【Methods】  Subjects with YGTC or thin-white tongue coating (TWTC) were recruited from December 1, 2021 to October 30, 2022, and the TC and fecal samples were collected. Samples were subjected to both whole-genome shotgun (WGS), and 16S rRNA gene sequencing. The α-diversity analysis, principal component analysis (PCA), and Spearman correlation analysis were performed for two groups. Ultra-performance liquid chromatography combined with tandem mass spectrometry (UPLC–MS/MS) analysis was used to analyze metabolomics and enrichment of metabolic pathways.
【Results】  The results revealed 20 YGTC participates and 19 TWTC participates. At the genus
level, the dominant bacterial species of TC flora and intestinal flora in the two groups were roughly the same, but the relative kurtosis difference was marked, and the abundance of potentially pathogenic bacteria in TC and fecal samples of YGTC subjects was higher. There were 9 down-regulated microorganisms in the TC samples, 26 down-regulated microorganisms, and 6 up-regulated microorganisms in YGTC subjects. The α-diversity analysis indicated that the Chao and abundance-based coverage estimator (ACE) indices of TC bacteria in the YGTC subjects showed a decreasing trend, but the difference was not statistically significant (P > 0.05). The α-diversity of fecal samples and the Chao and ACE indices decreased significantly (P < 0.05). PCA showed that the microflora structure of TC and fecal samples were significantly different between the two groups. Spearman correlation analysis showed that there was no correlation between TC and fecal microorganisms at phyla and genus levels in the same subjects (P > 0.05). The metabolomics results demonstrated that fumarate reductase, V/A ATPase, and phosphatidylethanolamine were increased, and glycerate-3p, UDP-glucose, and quinone oxidoreductase metabolites were decreased in YGTC TC samples. Inosine
monophosphate (IMP), uridine monophosphate (UMP), and gamma-aminobutyric acid(GABA) were increased in YGTC fecal samples, while the contents of ribo-5P, histidine, biotin,and cobalamin were decreased. Metabolic pathway analysis indicated that the abundance of the TC and fecal samples of the YGTC subjects was relatively low in various metabolic pathways, including amino acid metabolism, carbohydrate metabolism, nitrogen metabolism, and energy metabolism.
【Conclusion】  Structural and functional changes in TC and GIT microbiota or metabolite markers could be potential biological bases of YGTC formation.
		                        		
		                        		
		                        		
		                        	
7.Validity and reliability of the Chinese Attention to Positive and Negative Inventory in college students
Qin DAI ; Zhengzhi FENG ; Shuang XU ; Junrun XIE ; Keyu LIU ; Yongju YU ; Xiaoxia WANG ; Rui ZHANG ; Ying HE ; Jiawen LI ; Jing LI ; Yunbo LIU ; Xiuna LIU ; Cuihua ZHANG ; Leifei WANG ; Xiaoxia YANG ; Qiuping GAO ; Zailing HAN
Chinese Mental Health Journal 2015;(5):395-400
		                        		
		                        			
		                        			Objective:To translate the Attention to Positive and Negative Inventory(APNI)and analyze the validity and reliability in Chinese undergraduates sample,to offer a convenient and reliable tool of measuring the cognitive bias for national researchers. Methods:The English-version APNI went through translation into Chinese, retroversion into English,translation into Chinese again,and revision several stages. Two parts of samples (1450 Chinese college students)were surveyed. Sample one (n=1000)was used for item analysis,exploratory factor a-nalysis (EFA),concurrent validity and reliability analysis,while sample 2 (n=450)was used for confirmatory fac-tor analysis (CFA). Totally 68 subjects of sample 1 were randomly chosen and resurveyed with an interval of one week. Beck depression inventory (BDI-II)and patient health questionnaire (PHQ-9)was used for concurrent validi-ty. Results:Item analysis indicated that the 22 items of Chinese APNI had good discriminability. EFA focused onattention to positive information(API)and attention to negative information(ANI)two factors. CFA showed good model fit (χ2 =1376,RMESA=0. 09,CFI=0. 94). Concurrent validity result showed that the total scores of BDI-II and PHQ-9 was negatively correlated with total scores of API (r=-0. 24,-0. 29,Ps<0. 01 ),and posi-tively correlated with total scores of ANI (r=0. 36,0. 31,Ps<0. 01). The Cronbach'αcoefficients of API and ANI sub-scale were 0. 86 and 0. 82,while the retest reliability coefficients were 0. 79 and 0. 62. Conclusion:It suggests that the Chinese APNI has good validity and reliability in a sample of college students,which could be used to eval-uate the cognitive bias of Chinese college students.
		                        		
		                        		
		                        		
		                        	
8.THE INPUT AND OUTPUT OF HEALTH HUMAN RESOURCE FOR COUNTY-LEVEL HOS-PITALS IN WESTERN CHINA
Yin ZHANG ; Zhengzhi LI ; Lingui LI
Modern Hospital 2015;(10):1-4
		                        		
		                        			
		                        			Objective To analyze the inputs and outputs of Health Human Resource for County -level Hos-pitals in Western China , discuss the reasons for low efficiency and quality , and provide references for improving the efficiency and quality of health human resources .Methods Using rank-sum ratio to evaluate the health human re-sources of 33 county -level hospitals of 11 provinces in western China , and to compare the evaluation results . Results In the comprehensive analysis of human input and output of health human resources between 11 provinces , according to the health human resources efficiency level of 11 provinces into third gear:a hard stop ( high-grade):Sichuan, Guangxi;second gear (mid-range): Gansu, Guizhou, Yunnan, Shaanxi, Ningxia, Inner Mongolia, Ti-bet, Xinjiang;third gear (low-grade):Qinghai.Conclusion In the nationwide perspective , the efficiency of the western provinces of health human resources is lower , and we need to take measures to improve the efficiency of health human resources .
		                        		
		                        		
		                        		
		                        	
9.The relationship and the path model construction among stressful life events, social support and depression in People′s Liberation Army
Ran YU ; Liying GAN ; Xuecheng LI ; Zhengzhi FENG ; Guangyi ZHU ; Keyu LIU
Chongqing Medicine 2014;(15):1907-1909,1957
		                        		
		                        			
		                        			Objective To investigate the relationship among stressful life events ,social support and depression through researc‐hing a large number of Chinese army men ,then discovered the social psychological mechanism of the depression .Methods 11 ,400 officers and soldiers were tested with three scales ,the center for epidemiologic studies depression scale ,life events scale and social support scale .The differences between groups were determined with the variance ,SPSS 18 .0 software and AMOS7 .0 were used to analyse and build model .In addition ,we built the path model of life events and social support on depression with AMOS 7 .0 soft‐ware .Results (1)There is a significant positive correlation between Chinese soldiers depression levels and life events (r=0 .382 , P<0 .01) .(2) There is a significant negative correlation between Chinese soldiers depression levels and the social support (r= -0 .379 ,P<0 .01) .(3) It was established the path model of life events ,the social support and depressive symptom level .Con‐clusion Depressive symptom is related to the military life events ,which may predict the occurrence of the depression .Moreover ,so‐cial support ,a protective factor for mental health ,can relieve the depression of officers and men .
		                        		
		                        		
		                        		
		                        	
10.Study on characteristics of physical self of head and neck cancer patients with depression
Yundong BAI ; Zhengzhi FENG ; Guoqing YANG ; Yi LI
Chinese Journal of Behavioral Medicine and Brain Science 2012;21(9):807-809
		                        		
		                        			
		                        			ObjectiveTo study the relationship between depression and physical self and related factors of head and neck cancer patients (HNCPs).MethodsOne hundred and twenty-eight HNCPs were assessed with self-rating depression scale,physical self scale,negative physical self scale and symptom checklist-90 (SCL-90).SPSS 16.0 was used to analyze the data.ResultsThe evaluation of appearance,sport characters and figure characters were significantly different between sexual groups,the average physical self scale level of the male patients was higher than that of the females (3.33 ± 0.56 vs.2.87 ± 0.32,P < 0.05).The appearance,sport characters,figure characters and sexual characters of physical self-concept were significantly different between age groups,the body satisfaction scale from higher to lower were under 45 years old patients,beyond 60 years old,between 46 and 59 years old.ConclusionThe evaluation of appearance is reversely correlated with the score of SCL-90,the evaluation of short,appearance and fat in negative physical self are positively correlated with the score of SCL-90.
		                        		
		                        		
		                        		
		                        	
            

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