1.Clinical characteristics and the result of surgery for penetrating eye injury after mine explosion
Journal of Medical Research 2008;56(4):51-56
		                        		
		                        			
		                        			Background: Penetrating eye injury caused by mine explosion is a severe ophthalmologic injury. It is rare in Viet Nam and there were no studies on this type of injury. Objectives: To describe the clinical characteristics and evaluate the outcomes of surgery for penetrating eye injury caused by mine explosions. Subjects and method: The prospective analysis was conducted on 34 patients (36 eyes) with penetrating eye injury presented at the Trauma Department of Viet Nam National Institute of Ophthalmology. They were followed up for two years. Results: Out of the \r\n', u'34 patients, 31 were men (91.2%). Types of injury: corneal tear 93.8%, lens damage: 100%, vitreous damage: 56.3%, retinal detachment 25%, intraocular foreign body 72.2%. Initial visual acuity less than 0.02 was 96.9%. The final visual acuity was improved to better than 0.02 in 58.3% of patients. The intraocular pressures were normalized in 72.2% of patients after treatment. Conclusion: Penetrating eye injury caused by exploding mines has very severe clinical features. Despite of improvements in surgical techniques and instruments, the final visual acuity was still poor. The visual outcomes primarily depended on initial damages to the eye.\r\n', u'
		                        		
		                        		
		                        		
		                        			Mine
		                        			;
		                        		
		                        			 Penetrating eye injury
		                        			;
		                        		
		                        			 Vitrectomy
		                        			
		                        		
		                        	
2.Study clinical characteristics and the results with topical steroid in the treatment of ocular alkali burns
Journal of Medical Research 2008;58(5):39-45
		                        		
		                        			
		                        			Background: Alkali burns are severe injuries of the eyes. Recently, using topical steroid in treatment of ocular alkali burns has provided better outcomes. However, there is no study on treating ocular alkali burns by topical steroid in Vietnam. Objective: To describe the clinical characteristics and assess the outcome with topical steroid used in the treatment of ocular Alkali burns. Subject and Method: The author performed a prospective analysis of 45 alkali eye burns at the Trauma department of the National Institute of Ophalmology, Hanoi. All patients were treated with topical steroid and vitamin C. Results: There were 19 eyes were mild injures, 26 eyes were severe injuries. 32.5% had a good visual acuity. None of patients with severe injuries had a good visual acuity. Complications: corneal opacity: 42.2%, elevated IOP 17.8%. Conclusion: Treatment of ocular alkali burns with topical steroid and vitamin C is not associated with corneal perforating and provide a good outcome.
		                        		
		                        		
		                        		
		                        			Alkali burn
		                        			;
		                        		
		                        			 Steroid
		                        			
		                        		
		                        	
3.Assessment of the trabeculectomy with 5 fluoruoracil in the treatment of post-traumatic glaucoma
Journal of Medical Research 2008;59(6):59-64
		                        		
		                        			
		                        			Background: The post-traumatic glaucoma is a major cause inducing blindness of traumatic eyes. Recent, researches have shown that 5 fluoruoracil (5 FU) combined with surgery, which have a better result in treatment of general glaucoma and post-traumatic glaucoma. Objectives: To describe the clinical characteristics of post - traumatic glaucoma and assess the results of trabeculectomy with intra-operative application of 5 FU. Subject and methods: A descriptive, prospective analysis was taken on 32 patients, who had trabeculectomy with intra-operative application of 5 FU from August 2005 to December 2007 in the Traumatic Department of National Institute of Ophthalmology. Results: Post-traumatic glaucoma was seen mainly in young adults 71.9%; anterior angle recession combined lesions accounted for 25%; cataract 62.5%; fluid in anterior chamber 25%; anterior haemorrhage 37.5%. The intraocular pressure (lOP) was successfully controlled at least up to the following six months in 93.8% and the visual acuity was 0.02 and better in 62.5%. Conclusions: Trabeculectomy with antimetabolite therapy is an effective procedure in reducing IOP in post - traumatic glaucoma.
		                        		
		                        		
		                        		
		                        			5 Fluorouracil
		                        			;
		                        		
		                        			 post-traumatic glaucoma
		                        			
		                        		
		                        	
4.Study on epidemiological characteristics of the Japanese Encephalitis in Ha Nam during 2001 - 2006
Thoang Dinh Dang ; Nga Thi Phan ; Yen Thu Nguyen ; Quyet Lap Nguyen
Journal of Preventive Medicine 2008;18(1):3-8
		                        		
		                        			
		                        			Background: Viet Nam is located in the epidemiological region of Japanese Encephalitis (JE). JE vaccine manufactured in Viet Nam has been used in the national vaccination program since 2003, but there has been no scientific study on the effectiveness of this program in Ha Nam province. Objectives: To investigate the epidemiology of JE and effectiveness of vaccinations in Ha Nam province from 2001-2006. Subjects and method: All residents in Ha Nam province, with the key focus group being JE cases. The retrospective and prospective epidemiological descriptive method was used. Results: The records of 148 cases of JE were collected. Among them, 42.5% (63 cases) were confirmed as JE by MAC-ELISA. The incidence and mortality rate were 1.29/100,000 and 0.12/100,000, respectively. Confirmed JE cases were found annually in all districts of Ha Nam province. However, it has been in decline, especially since the vaccination program was implemented for 1-5 year old children. The disease occurred in the summer with the peak in May and June (80.9% of total cases). Most of the cases were children under 15 years old (98.4%). The highest incidence rate was 6.4/100,000; 5.5/100,000 and 5.3/100,000 in the children aged 5-9, 1-4 and under 1 year old, respectively. Conclusion: The vaccination program appeared effective in reducing the mortality and morbidity of JE among children in Ha Nam province.
		                        		
		                        		
		                        		
		                        			Japanese Encephalitis
		                        			;
		                        		
		                        			 epidemiology
		                        			
		                        		
		                        	
5.Evaluation of vitrectomy for severe penetrating eye injury in children
Journal of Medical Research 2007;47(1):73-77
		                        		
		                        			
		                        			Background: Severe penetrating eye injury is a common emergency in ophthalmology. Objectives: The evaluation results and complications following vitrectomy in severe penetrating injury in children. Subjects and method: This study included 136 eyes with penetrating eye injury, who were treated at the Trauma department of National Institute of Ophthalmology, Hanoi \ufffd?Vietnam from 1999-2000. Vitrectomy was performed through the limbal and pars plana in 135 patients, 105 boys and 30 girls. Results: Remove intraocular foreign body: 11%, procedure for retinal detachments: 14%. The common functional success (visual acuity of 5/2000 or better) rate was 55,1%. Functional success: absent retinal detachment: 60,7%; present: 21,1%. Anatomic success rate was 66,2%. 4 eyes (2,9%) were eviscerated. Complications of the surgery were: iridocyclite, edema of the cornea, hemorrhage, hyphema. Conclusion:Vitrectomy techniques showed its good effect in treating penetrating eye injury in children. Presence retinal damage and endophthalmitis have significant effect on the final visual outcomes.
		                        		
		                        		
		                        		
		                        			Eye Injuries
		                        			;
		                        		
		                        			 Penetrating/ surgery
		                        			;
		                        		
		                        			 Vitrectomy
		                        			;
		                        		
		                        			 Child
		                        			;
		                        		
		                        			 
		                        			
		                        		
		                        	
6.The value of urocytogramme in normal menstruation period of adolescent girls
Yen Thi Thuy Hoang ; Nhan Thu Nguyen ; Hop Van Tran
Journal of Medical Research 2007;55(6):168-172
		                        		
		                        			
		                        			Background:The urocytogramme is a certain laboratory tests, although older. By studying the cellular elements from the wall of the bladder trigone desquamated in the urine, it allows cyto-hormonal diagnosis. It allows to assess the presence and importance of the biological effect of sex steroids. This examination is not commonly used because they are poorly known in our country. It's a review of how simple, noninvasive, inexpensive. Objectives:This study aims to learn about the value of urocytogramme in normal menstruation period of girls. Subjects and method:A study was conducted on 143 high school girls of Hai Ba Trung Secondary School, Hue city. The mean age was 15\xb18 months, completely puberty; the average weight was 45.7\xb16.8 kg; average height was 156.8 \xb18.5 cm. The duration of study was from September 2006 to May 2007. Results:Urocytogramme had the index which changed according to the phase of the menstrual cycle and correlated closely with sex hormone concentrations in the ovulatory phase. The IK index had the value in ovulation diagnostic phase with the sensitivity and specificity concentrations equivalent to LH and plasma Estradiol. Conclusion:Urocytogram was a useful test for the diagnosis of in normal menstruation period of adolescent girls. It was easy, cheap and truly reflected oestrogen activity to help doctors making decision for the treatment of lasting amenorrhea disorders.
		                        		
		                        		
		                        		
		                        			Menstrual Cycle
		                        			;
		                        		
		                        			 Adolescent
		                        			
		                        		
		                        	
7.Assessment of the outcomes of surgical in the treatment of glaucoma after penetrating eye injury.
Journal of Medical Research 2007;52(5):12-16
		                        		
		                        			
		                        			Background: Penetrating eye injury is common cause blind or many long-term complications later. One of the complications such as glaucoma in the eye. There were some research on glaucoma after penetrating eye injury, but no reports about the treatment of glaucoma. Objectives: To describe the clinical characteristics and assess the outcomes of surgery in the treatment of glaucoma after penetrating eye injury. Subjects and method: The author performed a prospective analysis of 32 eyes the underwent surgery causes by glaucoma after penetrating eye injury at Trauma department of National Institute of Ophthalmology. Follow up period: 6 months. Data was processed by using medical statistics methods on SPSS 10.5 software. Results: Of the 32 patients, 21 were men (65.6%) and 11 were women (34.4%). Localization of the injury: in the cornea 93.8%; lens damages 100%; vitreous organization 56.3%; retinal detachment 12.5%. Functional success (visual acuity >0.02): 18.8%, 4 eyes were enucleated. The normal intraocular pressure after surgery was 71.9%. Conclusion: The clinical characteristics of glaucoma after penetrating eye injury are complicated and multivariable. The rate of normal pressure after treatment was 71.9%.
		                        		
		                        		
		                        		
		                        			Glaucoma/surgery
		                        			;
		                        		
		                        			 Eye Injuries
		                        			;
		                        		
		                        			 Penetrating
		                        			;
		                        		
		                        			 
		                        			
		                        		
		                        	
8.Study on Japanese encephalitis immunization and control policy in Viet nam
Journal of Preventive Medicine 2005;15(2):71-74
		                        		
		                        			
		                        			National Institute of Hygiene and Epidemiology combined with International Vaccine 
Institute to conduct a qualitative study on Japanese encephalitis immunization and control policy in Viet Nam in 2002. The study applied quick assess method including collection information from many source and interview. In 2 months, the study determined experienced lesson of Vietnam in giving Japanese encephalitis vaccine into open immunization program. The study showed that policy of Japanese encephalitis immunization in Vietnam was effect due to suitable strategies and correct decisions.
		                        		
		                        		
		                        		
		                        			Encephalitis, Japanese
		                        			;
		                        		
		                        			 Immunization
		                        			
		                        		
		                        	
9.To evaluate the efficacy of Vietnam produced vaccine of Japanese encephalitis
Journal of Practical Medicine 2003;442(2):22-24
		                        		
		                        			
		                        			On 293 healthy children of 2-4 years old of age in the Commune Song Ho, Thuan Thanh District, Bac Ninh Province, of them 101 children were vaccinated with Vietnam produced vaccine and 102 with Biken vaccine. Results showed that Vietnam produced vaccine manifested an antibody response of 100% with Tb antibody valent (GMT) of 3.48. After 1 year of basal immunization, GMT decreased by 2.49 but it was still higher than 2.5 times of minimal value and after the 3rd injection of vaccines GMT increased by > 4.01 times higher than the basal immunization level. In comparing with Biken vaccine, the Vietnam produced vaccine has a GMT antibody response rate and a long duration of life of antibody with high level comparable to the Japan produced vaccine
		                        		
		                        		
		                        		
		                        			Child
		                        			;
		                        		
		                        			 Encephalitis, Japanese
		                        			;
		                        		
		                        			 Japanese Encephalitis Vaccines
		                        			
		                        		
		                        	
10.Some remarks on measles outbreaks in the Northern Region of Vietnam, 2001
Journal of Preventive Medicine 2003;13(1):17-22
		                        		
		                        			
		                        			In 2001, there were 37 outbreaks of measles with various sizes in the Northern region. 36 out of 37 outbreaks were confirmed by MAC-ELISA. Percentage of positive sera was 86.3%. The measles outbreaks became more seriously in mountainous areas. The measles cases occurred all the year, and focused on January to May, with the peaks were January and February. The distribution of measles by age group has changed to group of older children, with most of cases were in 5-15 age group. 64.5% of measles cases were not immunization.  The ratio of non-immunization to immunization increased with age group
		                        		
		                        		
		                        		
		                        			Measles
		                        			;
		                        		
		                        			 Diseases
		                        			;
		                        		
		                        			 Child
		                        			
		                        		
		                        	
            
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