1.Historical evolution and clinical application of classical prescription Yigongsan
Na CHEN ; Jingxian GUO ; Yanqi CHU ; Leilei GONG ; Xinhai JIANG ; Xiao HU ; Lan ZHANG
China Pharmacy 2024;35(1):119-123
Yigongsan, derived from QIAN Yi’s Key to Therapeutics of Children’s Diseases in the Song Dynasty, is a classic pediatric prescription that is included in the Catalogue of Ancient Classic Prescriptions (the Second Batch of Pediatrics) released by the National Administration of Traditional Chinese Medicine in 2022. This paper verifies and analyzes the historical origin, composition, dosage, processing, decoction method and efficacy of Yigongsan by systematically combing ancient books and modern documents. As a result, Yigongsan is composed of five herbs: Panax ginseng, Poria cocos, Atractylodes macrocephala, Citrus reticulata and Glycyrrhiza uralensis, of which P. cocos should be peeled, A. macrocephala is fried with soil, G. uralensis is roasted with honey while P. ginseng and C. reticulata are raw products. According to the dosage of ancient and modern times, each medicinal herb must be ground into fine powder, 1.6 g for each, added with 300 mL of water, 5 pieces of Zingiber officinale, and 2 Ziziphus jujuba, decocted together to 210 mL, and taken before meals. In ancient books, Yigongsan is used to treat vomiting, diarrhea, spleen and stomach deficiency, chest and abdominal distension, and lack of appetite, etc. Modern research showed that Yigongsan could also be used in the diseases of immune system, respiratory system, blood system, etc., involving infantile anorexia, asthma, anemia, tumors and so on.
2.Analysis on the training programs of geriatric clinical pharmacists in China and the United States
Chen LIU ; Yanqi CHU ; Xiangrong BAI
China Pharmacy 2024;35(14):1781-1785
OBJECTIVE To compare the general status of training programs for geriatric clinical pharmacists in China and the United States, and provide a reference for further optimizing training programs of geriatric clinical pharmacists in China. METHODS Retrieved from the American Society of Health-System Pharmacists (ASHP) website and the Chinese Hospital Association website, the detailed information and data on training outline, institution type/scale, enrollment number, training contents, project application conditions and graduation assessments for clinical pharmacists in geriatric field were collected and statistical analysis was performed using Excel software. RESULTS & CONCLUSIONS As of January 12, 2024, ASHP provided 24 geriatric clinical pharmacist training programs and 25 positions available for application in the postgraduate year two training, which provided compensation. The training base involved hospitals and pharmaceutical colleges, with varying scales. Applicants needed to obtain a doctor of pharmacy and complete postgraduate year one training. ASHP had designed detailed training objectives for the four essential skills of basic patient care, advanced patient care, leadership and management skills, and knowledge education and teaching dissemination. Each training base could appropriately add optional skills such as academic skills, long-term care skills and other skills according to its characteristics, developed a student rotation plan, and conducted assessments and evaluations at multiple time points during the training process. There were 5 training programs for geriatric clinical pharmacists in China, with 15 positions, which didn’t provide compensation; training bases were all third-grade class A hospitals with relatively large scale. The applicant needed to obtain a bachelor’s degree or above, and different years of work were required based on their major and degree level. The Pharmaceutical Specialized Committee of the China Hospital Association had established a detailed training outline, proposing specific training objectives on theoretical knowledge, practical skills, scientific research thinking, etc. The training base organized assessments and evaluations at the time of enrollment, completion of specified content training, and graduation. According to the experience of the US, it is recommended to provide differentiated knowledge and skills training for students at different levels, flexibly arrange rotating departments, require students to work independently and deeply participate in clinical teaching and research work, conduct multiple and various forms of assessments, and adjust learning plans in a 13264273306@126.com timely manner to comprehensively enhance their abilities.
3.Investigation on knowledge,attitude and practice of cephalosporins skin test among medical staff in China
Jiaming LIU ; Yanqi CHU ; Lan ZHANG
Chinese Journal of Pharmacoepidemiology 2024;33(6):621-631
Objective To analyze the current situation and influencing factors of knowledge,attitude and practice among medical personnel in medical institutions in China regarding skin testing of cephalosporins,to provide reference for standardizing medical behavior related to skin test.Methods A self-designed questionnaire on knowledge,attitude and practice of cephalosporins skin test was used to survey medical staff in China.The questionnaire QR code was distributed to medical institutions nationwide through WeChat,and participants participated voluntarily and anonymously.Knowledge,attitude,and practice scores of medical staff with different educational level,job positions,professional titles were calculated,and influencing factors were analyzed using Wilcoxon rank sum test,multiple linear regression analysis,and other statistical methods.Results 873 medical staff from 205 medical institutions in 30 provinces participated in this survey.The scores of knowledge(total score 16),attitude(total score 20)and practice(total score 20)in the cephalosporins skin test were 10(8,12),13(12,15)and 12(9,15),respectively.The results of multiple linear regression showed that educational level,job position and professional title were correlated with knowledge and attitude scores(P<0.05).Graduate medical personnel had better knowledge and positive attitudes than specialized medical personnel.Pharmacists had better knowledge and a positive attitude than doctors and nurses.Medical personnel with intermediate and senior professional titles had better knowledge mastery and a positive attitude than those with junior and lower professional titles.Knowledge level is positively correlated with attitude(P<0.05).Gender,job position and professional title were correlated with practice scores(P<0.05).Female medical staff exhibited less positive practice than the male medical staff.Nurses exhibited more positive practices than pharmacists.Medical personnel with senior professional titles exhibited more positive practice than those with junior and lower professional titles.Knowledge,attitude was positively correlated with practice(P<0.05).There was no statistically significant difference in the mediating effect of attitude on the influence of knowledge on practice(P=0.085).Conclusion The knowledge,attitude and practice of cephalosporins skin test among medical personnel in China need to be strengthened.Training programs should be tailored to address the differences in knowledge,attitude,and practice among medical staff in different positions and professional titles,to enhance knowledge levels,establish positive attitudes,and standardize skin test-related medical behavior.
4.Historical Evolution and Clinical Application of Famous Classical Formulas Zhulingtang
Na CHEN ; Jingxian GUO ; Yanqi CHU ; Leilei GONG ; Lan ZHANG
Chinese Journal of Experimental Traditional Medical Formulae 2023;29(18):146-155
The classic formula Zhulingtang, derived from the medical work Treatise on Cold Damage (《伤寒论》) compiled by ZHANG Zhongjing, a medical sage in the Eastern Han Dynasty, has been included in the Catalogue of Ancient Classic Formulas (First Batch) published by the National Administration of Traditional Chinese Medicine in 2018. Using the method of textual research, this study systematically reviewed ancient and modern literature to conduct a historical and textual analysis of Zhulingtang, including its origin, composition, dosage, processing, decoction methods, efficacy, and applications. A total of 733 pieces of relevant information related to Zhulingtang were collected, involving 206 ancient Chinese medical texts, with 52 of them providing detailed records of the composition, dosage, processing, and efficacy of Zhulingtang. The results of the analysis showed that Zhulingtang was composed of Polyporus, Poria, Alismatis Rhizoma, Asini Corii Colla, and Talcum. Polyporus and Poria should be used without their peels, Asini Corii Colla should be stir-fried with clam powder, and Talcum should be ground into powder or soaked in water. Based on the conversion of ancient and modern dosages, Polyporus, Poria, Alismatis Rhizoma, and Talcum, 15.63 g for each one, were decocted with 800 mL of water to 400 mL. Then the drug residue was removed, and 15.63 g of Asini Corii Colla was added to the drug juice for melting by heating. The decoction should be taken warm, 140 mL each time, three times a day. Zhulingtang has the effects of promoting diuresis, nourishing yin, and clearing heat, and it is mainly used to treat water-heat combination syndrome, characterized by symptoms such as difficult urination, fever, and thirst. Modern research indicates that Zhulingtang is commonly used to treat diseases such as cirrhotic ascites, chronic glomerulonephritis, nephrotic syndrome, diarrhea, and urinary tract infections. This study provides key information about the famous formula Zhulingtang, which can serve as a reference for further development and research on its application.
5.Working Mode and Case Analysis of the First Pharmaceutical Ward Rounds in Our Hospital
Wei ZHUANG ; Suying YAN ; Xiaolan LIN ; Fei CHEN ; Li GAO ; Yingnan FENG ; Jing TANG ; Beibei JIA ; Yanqi CHU
China Pharmacy 2021;32(17):2129-2133
OBJECTIVE:To est ablish the working mode of the first pharmaceutical ward rounds of clinical pharmacists in our hospital,in order to provide a useful reference for establishing a national standardized pharmaceutical ward rounds model. METHODS:By sharing the clinical cases of the first pharmaceutical ward rounds ,the work content and process of the first pharmaceutical ward rounds in our hospital were introduced. RESULTS & CONCLUSIONS :The clinical pharmacist ’s first pharmaceutical ward round in our hospital mainly includes self introduction of clinical pharmacists ,diagnosis of patients ’condition under the guidance of doctors ,collection and evaluation of patients ’previous medication information (including previous medication varieties ,usage methods ,efficacy and safety evaluation ),assistance for doctors in formulating initial treatment plan , carrying out initial medication and diet education ,and intensive communication and cooperation with nurses. The development of first pharmaceutical ward rounds promotes the rational use of drugs in clinic ,elevates the hospitalization satisfaction of patients and improves the professional quality of clinical pharmacists.
6.Literature Analysis for Clinical Application and Existing Problems of 2 Medical Order Auditing Modes
Yutong ZONG ; Suying YAN ; Yanqi CHU
China Pharmacy 2020;31(7):879-883
OBJECTIVE:To summari ze clinical application and existing problems of artificial auditing and information-based medical order auditing modes so as to provide reference for improving rational medication. METHODS :Collecting data by literature search ,using “Prescription auditing ”“Medical order auditing ”“Prescription pre-auditing ”“Medication error ” “Medication-related problems ”“Medication safety ”“Alert fatigue ”“Medication review ”“Decision support medication review ” “Real-time medication review ”“Real-time prescription surveillance ”“Clinical alarms decision support systems ”“Clinical pharmacy information systems ”“Medication errors ”“Medication related problem ”as keywords ,the related literatures from Jan. 2000 to Nov. 2019 were retrieved from CNKI ,Wanfang database ,PubMed,Embase,Web of Science and other databases. The clinical application and existing problems of 2 medical order auditing modes were analyzed and summarized. RESULTS & CONCLUSIONS:The artificial auditing mode can reduce medication-related problems (such as poor drug treatment effect , untreated symptoms or indications ,potential adverse drug events ,unnecessary drug treatment ,etc.),improve life quality of patients,but can not decrease the mortality and the length of hospitalization stay ;there are some problems ,such as many pharmacists needed for medical order auditing ,insufficient auditing time ,different auditing standards ,auditing time lagging. The information-based medical order auditing mode can reduce medication-related problems ,save auditing time ,reduce the incidence of medication errors ,reduce unreasonable medical orders ,and improve audit efficiency. Compared with the artificial auditing mode ,it has certain advantages ,but there are problems such as alarm fatigue. At present ,the domestic medical order auditing mode is dominated by artificial audit mode ;the information-based medical order auditing mode is still in the initial stage ,and the most attention is paid to its influence on the qualified rate of prescription ,while the research on the incidence of adverse events and other clinical effects is less. Later ,the 2 midical order can be D181100000218002); improve to provide a reference for medical order auditing of 2019 hospital pharmacy personnel.
7.Comparison of two training methods in rehabilitation training for postoperative patients with orbital fracture
Lijuan ZHOU ; Yanqi DOU ; Hang CHU ; Guixia DONG
Chinese Journal of Modern Nursing 2020;26(21):2867-2871
Objective:To explore the effects of helmet-eyeball movement training system in rehabilitation training among orbital fracture patients.Methods:From April to December 2018, we selected 60 patients with orbital fracture surgeries by the same doctor in the Ophthalmology Department, Beijing Tongren Hospital, Capital Medical University, with the method of convenience sampling as the research objects. All patients were randomly divided into experimental group and control group, 30 cases in each group. Control group carried out the eyeball movement training with the fingers of patients as visual markers, while experimental group implemented the training with the helmet-eyeball movement training system. Diplopia rating and binocular stereoscopic vision function of patients of two groups were compared before training, one week, one month and three months after training.Results:At one and three months after training, the diplopia rating and static/dynamic stereoscopic vision function of patients in experimental group were better than those in control group with statistical differences ( P<0.05) . Conclusions:Helmet-eyeball movement training system can improve the training effect of patients and help them restore stereoscopic vision.
8.Status Quo of Pharmaceutical Care and Training Needs Research of Primary Pharmaceutical Staff Based on 9 Provinces(Regions,Cities)Investigation
Jianghua SHEN ; Shujie WANG ; Yan ZENG ; Yanqi CHU ; Yuqin WANG
China Pharmacy 2018;29(6):843-847
OBJECTIVE:To provide reference for exploring the way to improve the ability of pharmaceutical care in primary pharmaceutical staff. METHODS:Questionnaire survey was conducted among pharmaceutical staff(including head of pharmacy department),director/vice-director of hospital in charge of pharmacy,medical staff and patients from primary medical institutions in 9 provinces(regions,cities). The results of investigation were analyzed statistically. RESULTS:A total of 77 primary medical institutions involved in the survey. Totally of 2 273 questionnaires were sent out,and 2 248 effective questionnaires were collected with effective recovery rate of 98.9%. Among effective questionnaires,278 questionnaires were filled out by pharmaceutical staff (68 by head of pharmacy department),48 by director/vice-director of hospital in charge of pharmacy,771 by medical staff and 1 151 by patients. Results of survey showed that only 140 pharmaceutical staff had obtained pharmacy practice qualification,accounting for 50.4%. The surveyed primary medical institutions provided limited pharmaceutical care projects,and the projects with high proportion were medication explanation(85.7%)and medication consultation(84.4%). The establishment of Health Service Record Card in elderly patients(19.5%),the development of chronic disease management(23.4%)and the development of chronic disease related pharmaceutical knowledge publicity at the primary level(37.7%)took up low proportion relatively. Overall satisfaction of surveyed medical staff to pharmaceutical care of pharmaceutical staff was general(77.2%). Surveyed patients greatly satisfied with the attitude of pharmaceutical staff(85.5%)but overall satisfaction of them to professional knowledge of pharmaceutical staff(78.2%)was general. Surveyed pharmaceutical staff training needs in descending order were medication explanation(74.5%),medication counseling(71.9%)and providing pharmaceutical information(64.0%). However,the projects which had low proportion of training needs included chronic disease management(22.3%)and lifestyle guidance (27.0%),etc. The more favorite training forms in descending order were further study in medical institution at higher level(65.4%),expert lectures(60.1%)and training in the training base (57.9%). CONCLUSIONS:The primary medical institutions provided limited pharmaceutical care. It is necessary to further explore and standardize pharmaceutical care criteria. The overall satisfaction of medical staff and patients on pharmaceutical care of pharmaceutical staff is not high in primary institutions,and it needs to be further improved. The related pharmacy training for primary pharmaceutical staff still needs to be strengthened,and can be conducted according to the favorite form of training so as to improve the ability of pharmaceutical care.
9.Construction of the teaching case library on clinical pharmacy for pharmacy residents
Yan ZENG ; Shujie WANG ; Yanqi CHU ; Suying YAN
Chinese Journal of Medical Education Research 2018;17(10):1072-1076
A teaching case library of clinical pharmacy was constructed to improve case teaching for pharmacy residents. Through establishment of draft requirement and organizing a group of authors consti-tuted by preceptors of pharmacy residents, the teaching cases were written, the contents and forms of which were assessed by teaching demonstration, interactively examined and revised by fellow teachers, audited and screened by senior pharmacists , and thus a case library was collaborated , processed and established . Finally, a case library was formed, which included 11 systems, such as endocrine, cardiovascular and neu-rological systems, and 32 cases of drug treatment for common diseases in each system. The construction ofcase library has enhanced the teaching consciousness and skills of resident pharmacists' teaching team. This case library will become an important resource for teaching and scientific research in the future.
10.Establishment, Implementation and Evaluation of a Case-based Education Program for Resident Pharmacists
Yan ZENG ; Shujie WANG ; Yanqi CHU ; Suying YAN
China Pharmacist 2017;20(8):1501-1504
Objective: To establish an education program for resident pharmacists to improve clinical problem solving skills with pharmaceutical knowledge.Methods: A case-based education program for resident pharmacists with drug knowledge was established after a questionnaire survey in resident pharmacists and the discussion with clinical teachers.A teaching team was built and the resident pharmacists were divided into several study groups.After a pilot run, the program was operated in pharmacy department.The program was divided into 10 sections by drug indications, and each section was composed of basic drug knowledge lecture and case discussions, which mobilized the study initiative of resident pharmacists.At the half time, resident pharmacists and clinical teachers participated in a midterm survey by a questionnaire.Results: More than 95% resident pharmacists and teachers believed that basic drug knowledge lecture before case discussion was necessary, and compared with previous trainings, the program could further increase study interests of resident pharmacists and improve the clinical problem solving skills.However, 33.3% resident pharmacists and 60% teachers thought the cases were difficult, and 18.5% resident pharmacists and 10% teachers disagreed the cases were close to the actual work.Conclusion: The program is effective in drug knowledge training for resident pharmacists, which can improve pharmaceutical care for patients, while further modifications are still needed to satisfy the demands of resident pharamcists with different working years.

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