Background: and Purpose To assess the long-term outcomes of intracranial dural arteriovenous fistula (DAVF) treated with stereotactic radiosurgery (SRS) alone or embolization and SRS (Emb-SRS) and to develop a grading system for predicting DAVF obliteration. Methods: This multi-institutional retrospective study included 200 patients with DAVF treated with SRS or Emb-SRS. We investigated the long-term obliteration rate and obliteration-associated factors. We developed a new grading system to estimate the obliteration rate. Additionally, we compared the outcomes of SRS and Emb-SRS by using propensity score matching. Results: The 3- and 4-year obliteration rates were 66.3% and 78.8%, respectively. The post-SRS hemorrhage rate was 2%. In the matched cohort, the SRS and Emb-SRS groups did not differ in the rates of obliteration (P=0.54) or post-SRS hemorrhage (P=0.50). In multivariable analysis, DAVF location and cortical venous reflux (CVR) were independently associated with obliteration. The new grading system assigned 2, 1, and 0 points to DAVFs in the anterior skull base or middle fossa, DAVFs with CVR or DAVFs in the superior sagittal sinus or tentorium, and DAVFs without these factors, respectively. Using the total points, patients were stratified into the highest (0 points), intermediate (1 point), or lowest (≥2 points) obliteration rate groups that exhibited 4-year obliteration rates of 94.4%, 71.3%, and 60.4%, respectively (P<0.01). Conclusions SRS-based therapy achieved DAVF obliteration in more than three-quarters of the patients at 4 years of age. Our grading system can stratify the obliteration rate and may guide physicians in treatment selection.

Background/Aims: Application of polyglycolic acid (PGA) sheets using fibrin glue in post-endoscopic submucosal dissection (ESD) ulcers to prevent bleeding has been reported to be difficult with the conventional delivery method because of gravity. This study assessed the usefulness of the envelope-based delivery system with and against gravity in living pigs. Methods: PGA sheets were applied on post-ESD ulcers with and against gravity six times each using the conventional and envelope methods, respectively. The PGA sheet delivery time and the endoscopic and histological findings of the treated ulcer floors were compared. Results: With gravity, the median PGA sheet application time was 1.00 (0.68–1.30) min/cm2 and 0.32 (0.18–0.52) min/cm2 with the conventional and envelope techniques (p=0.002), respectively, and against gravity, it was 1.20 (1.13–1.63) min/cm2 and 0.50 (0.39–0.58) min/cm2 (p=0.002), respectively. Against gravity, the endoscopic and histological findings revealed that the conventional group had insufficient fixation of the PGA sheets, but the envelope groups had sufficient fixation. The results with gravity were similar between the groups. Conclusions The envelope method makes it possible to deliver PGA sheets to the stomach quickly and cover ulcers appropriately both with and against gravity in living pigs.

We report a case of Takotsubo cardiomyopathy that developed after elective coronary artery bypass grafting (CABG) in an 80-year-old woman. She had been given a diagnosis of unstable angina complicated with mild hypertrophic obstructive cardiomyopathy (HOCM). Her cardiac index began to fall 7 h postoperatively, and we needed to infuse fluids and increase dopamine dose (up to 5 µg/kg/min) to maintain cardiac index and blood pressure. CPK-MB level increased up to 140 IU/l at 12 h postoperatively. Transthoracic echocardiography showed akinesis and ballooning of the apex and hyperkinesis of the base with accelerated left ventricular outflow tract (LVOT) flow and increased mitral regurgitation (MR). Emergency coronary artery angiography showed good patency of all bypass grafts and no new coronary lesion. We diagnosed Takotsubo cardiomyopathy. To improve the hemodynamic status, we started intra-aortic balloon pumping (IABP) instead of adding catecholamines. Blood pressure and cardiac index had improved temporarily, but became unstable again because of increased LVOT pressure gradient and moderate-to-severe MR. LV wall motion gradually improved, but the hemodynamic status stayed unstable, but improved after removal of IABP. In general, the prognosis of Takotsubo cardiomyopathy is favorable with supportive care. However, when it is associated with LVOT stenosis and significant MR, low cardiac output syndrome can become intractable, thus we should manage critical conditions with extreme caution.

We report a case of septal branch aneurysm. A 61-year-old woman was referred to our hospital because of heart murmur. Septal branch aneurysm (25×15 mm) was diagnosed by echocardiography and coronary angiography, and followed up annually with multi-detector row computed tomography (MDCT). Nine years later, another aneurysm proximal to the known aneurysm, which protruded above the epicardium, has rapidly dilated from 5 to 11 mm. We therefore performed closure of the orifice of the septal branch concomitant with bypass grafting ; left internal mammary artery to distal LAD. After the procedure, the aneurysm in the septum had completely collapsed. Her postoperative course was uneventful.

We report a case of re-expansion pulmonary edema (REPE), which complicated mitral valve plasy via right small thoracotomy. A 56-years old man underwent mitral valve plasty for severe mitral regurgitation caused by P2 prolapse. After separation from heart-lung machine, massive yellow foamy secretion has begun to spout from the right side endotracheal tube and hypoxemia has ensued. Differential ventilation with high airway pressure and steroid pulse therapy could not counteract the exacerbation of hypoxemia. Echocardiography showed severe diffuse hypokinesis of left ventricular wall. Intra-aortic balloon pumping and percutaneous cardiopulmonary support (PCPS) were introduced, and they were very effective. After five-days' support, PCPS was successfully weaned. The patient recovered well. REPE complicated by mini-thoracotomy approach cardiac surgery, is rare, but can be fatal.

The aim of the present study was to investigate whether personal hamstring muscular activation increased by landing with the trunk bent forward. First, 14 healthy female university students were instructed to perform normal drop landing from a 40 cm-high box on both legs. Second, subjects were directed to perform drop landing with the trunk bent forward. Using images obtained from a high-speed video camera, the upper center of mass was calculated in the sagittal plane for determining the differences in these landings. For 0.1 second after toe contact, the muscular activation of quadriceps femoris and hamstring muscles was analyzed using an electromyogram (EMG), and these findings were compared between the 2 types of landings. There was no significant difference in the activation of quadriceps femoris, but the activation tended to decrease during landing with the trunk bent forward. However, the activation of hamstring muscles increased significantly during landing with the trunk bent forward compared with that during normal landing. During landing with the trunk bent forward, the activation of hamstring muscles increased, and the activation of quadriceps femoris tended to decrease. Because contraction of hamstring muscles decreases tension in the anterior cruciate ligament, the findings of this study may help in the prevention of anterior cruciate ligament (ACL) injury.

Purpose: The purpose of this study was to determine whether the impact on the body during landing in dancers is less than in non-dancers by using accelerometers and motion analyzer.Method: Eleven ballet dancers and 11 non-dancers participated in this study. Each subject was instructed to perform 3 types of landing from a height of 30cm: landing, silent landing and raise up landing. Markers were put on the iliac crest, greater trochanter, knee joint, lateral malleolus. The peak vertical and horizontal accelerations of the lumbar, peak vertical acceleration of the greater trochanter and the peak flexion angles of the hip and knee joints were measured after the trials.Result: In the raise up landing, the peak vertical acceleration of the lumbar region in dancers was less than that in non-dancers (p < 0.01), and the peak knee-flexion angle in dancers was greater than that in non-dancers (p < 0.01). There were no differences between the peak hipflexion angles of dancers and non-dancers.Conclusion: The impact on the lumbar during raise up landing was less in dancers. In raise up landing, the trunk tends to be fixed when the dancer stands upright. Moreover, dancers attenuated the shock to the lumbar region by increasing the knee-flexion angle to a greater extent than the non-dancers did. This result may indicate the importance of the knee joint flexion in attenuating the shock during landing and show that dancers excel in using their knees flexibly.

Purpose: Our aim was to investigate if such trunk muscular activation at standing could have an effect on their trunk muscular activation at leaning backward and forward and the strength of trunk isometric flexion and extension. Methods: The Electromyography (EMG) of lumbar paraspinals (LP) and rectus abdominis (RA) were recorded for 18 healthy volunteers at three positions (standing, leaning backward and leaning forward). In addition, the strength of maximum isometric of trunk flexion and extension were measured at sitting position. Then the flexion/extension (F/E) ratio was calculated. Results: 18 healthy volunteers were classified into Flexor group (n=5) and Extensor group (n=13). The RA-EMG of Extensor group was significantly larger than that of Flexor group at leaning backward position. Extensor group, also, had a higher strength of trunk isometric extension than that of Flexor group. Flexor group had a higher F/E ratio than that of Extensor group. Conclusion: A meaning of this study was to investigate that there were subjects who were higher paraspinals or rectus abdominis activation. Such difference was caused from muscular activation at working upper body and demonstrating of muscular strength, and this study may be helpful to develop study of physical therapy from now on.

Decrease in the hip extension range of motion (HE-ROM) can cause lumbar hyperlordosis. Hyperlordosis is one of the mechanisms underlying low back pain. A diagnosis of low back pain from hyperlordosis can be used to detect the area in which hyperlordosis occurs more easily—the upper or lower lumbar spine. Twenty-one men were recruited for this study. HE-ROM was measured manually. Lumbar alignment was measured on a bed in a prone position. We extended the subject's hip by bending the bed at 4 angles (0°, 10°, 15°, 30°) and measured the spinal alignment by using a SpinalMouse. The results showed that lumbar lordosis increased at the bed angles of 15°and 30°. Only when the bed angle was changed from 0° to 30°, the increased angle of the lumbar spine was negatively correlated to the HE-ROM (r=-0.46, p<0.05), particularly that of the lower lumbar spine (r=-0.47, p<0.05). These findings suggested that lower lumbar lordosis tends to increase in individuals with poor HE-ROM. Additionally, increase in lower lumbar lordosis is attributed to the tendency to have low back pain in the lower lumbar spine.

Purpose: The aim of the present study was to make an ankle destabilization device and investigate the effect of exercise with this device on peroneal muscles.Methods: Seventeen healthy subjects were instructed to undergo step movement exercise with the lower extremity 150 times on the spot using the ankle destabilization device. Before and after stepping, the reaction time and mean frequency of the peroneus longus and the peroneus brevis muscles were compared. While stepping with the device, muscular activity of the peroneus longus and the peroneus brevis was compared under both stable and instable conditions.Result: The results showed that peroneal reaction time didn't change after stepping with the device; but the frequency of peroneal muscle activity increased after stepping. While stepping, muscular activity of the peroneal muscles increased in an instable condition.Conclusion: The results suggested that stepping exercise with the device could be beneficial for peroneal muscles.