Objective To observe and compare the effects of four methods of anesthesia in patients with anorectal surgery.Methods One hundred patients with anorectal surgery were equally divided into the group Ⅰ (low-dose epidural anesthesia),group Ⅱ (epidural anesthesia),group Ⅲ (caudal) and group Ⅳ (local anesthesia) based on a random draw principles,each group of 25 cases.The onset time of anesthesia,patient satisfaction,postoperative adverse reaction and hemodynamics were observed in the 4 groups.Results The anesthesia onset time in the group Ⅰ and group Ⅳ were (4.12 ±2.11) min and (3.69 ±1.11) min,significantly shorter than group Ⅱ and group Ⅲ ((10.34 ±3.10) min and (12.55±3.23) min,P＜0.05).Anesthesia satisfaction of four groups were 96.0％ (24/25),84.0％ (21/25),64.0％ (16/25) and 40.0％ (10/25),the differences among 4 groups were statistically significant (P＜0.05),and the anesthesia satisfaction of guoup Ⅰ was the best.Four groups of postoperative urinary retention difference were not statistically significant (P＞0.05),but the postoperative nausea and vomiting(n =3),referred pain (n =12),headaches (n=4) and other adverse events in the group Ⅳ were significantly higher than the other 3 groups(P＜0.05).Differences between-groups and inner-group were not statistically significant of the intraoperative mean arterial pressure,oxygen saturation and pulse rates of the four groups (P＞ 0.05).Conclusion Compare to other anesthetic methods,low-dose epidural anesthesia in anorectal surgery applications with faster onset time of anesthesia and anesthesia satisfaction results,it has litter adverse reactions and maintain stable hemodynamics body,worthy applications.