1.A randomized controlled trial on the effect of Lutein Supplementation on Macular Pigment Optical Density and Macular Function in Pseudophakic Patients
Victor Ephraime V. Paulino ; Edward C. Uy ; Sherman O. Valero
Philippine Journal of Ophthalmology 2021;46(2):88-95
		                        		
		                        			Objective:
		                        			To evaluate the efficacy of oral lutein supplementation on macular pigment optical density (MPOD)
levels and macular function in pseudophakic eyes that underwent phacoemulsification. 
		                        		
		                        			Methods:
		                        			This was a prospective, randomized, parallel-arm, single-masked study comparing oral lutein supplement
20 mg/tablet (Lutax 20) with non-supplementation in pseudophakic eyes. We assessed MPOD, low-luminance
deficit (LLD), visual recovery time (VRT) using photostress test, and adverse events. One hundred twenty-eight
(128) eyes were enrolled and randomized 1:1 to active treatment (lutein supplementation) or no treatment (no
supplementation). The supplementation period was 12 weeks and patients were assessed every 4 weeks over a
period of 16 weeks.
		                        		
		                        			Results:
		                        			Sixty-four (64) eyes in each group completed the study. A significant increase in MPOD (p<0.001) was
observed in the lutein supplemented group, from 0.36 DU at baseline to 0.55 DU at week 12, with a mean increase
of 6.32 ± 1.72% per 4 weeks of supplementation compared with a mean MPOD decrease rate of 0.63 ± 0.48%
in the non-supplementation group. A significant reduction in LLD was observed in the lutein-treated group, from
LogMAR 0.063 at baseline to LogMAR 0.023 at Week 12 (p=0.003). VRT was also significantly shorter in the
treatment from a baseline of 83.06 to 68.80 seconds at Week 12 (p<0.001).
		                        		
		                        			Conclusion
		                        			Lutein supplementation (20 mg/tablet; Lutax 20) demonstrated a significant degree of MPOD
augmentation, and reductions in LLD and VRT among patients who underwent phacoemulsification with lens
implantation. 
		                        		
		                        		
		                        		
		                        			Lutein
		                        			;
		                        		
		                        			 Dietary Supplements
		                        			
		                        		
		                        	
2.Incidence of undetected error of refraction among school children in Barrio Santiago Elementary School San Pablo City
Manalo Joseph E ; Uy Edward C ; Inocencio Froilan P
Philippine Journal of Ophthalmology 2001;26(3):85-88
		                        		
		                        			
		                        			To detect the number of school children with errors of refraction and who are not wearing corrective glasses, a study was conducted at Barrio Santiago Elementary School.280 students fromGrade I to Grade IV were included.Visual screening, manifest and cyclopegic refraction was performed, and the results were compared and analyzed.63 (22.5%) had an undiagnosed myopic error of refraction detected by proper visual sc
		                        		
		                        		
		                        		
		                        			Human
		                        			;
		                        		
		                        			 Male
		                        			;
		                        		
		                        			 Female
		                        			;
		                        		
		                        			 Adolescent
		                        			;
		                        		
		                        			 Child
		                        			;
		                        		
		                        			 CYCLOPENTOLATE
		                        			;
		                        		
		                        			 OPHTHALMOLOGY
		                        			;
		                        		
		                        			 REFRACTIVE ERROR OF REFRACTION
		                        			
		                        		
		                        	
            
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