1.Efforts and Challenges in Implementing an In-Hospital Rapid Response System at Our Hospital
Toru MIZUMOTO ; Sadahiro KUBO ; Akihiko TABUCHI ; Satoshi TERANISHI ; Akiko TANIGUCHI ; Makoto SUGIURA ; Shinji ISHIKAWA ; Shinya YAMADA ; Mami SUZUKI ; Satomi SAEKI ; Kanoko HAMAISHI ; Kenichi YAMADA ; Yasuhiko HOSONO ; Megumi YOSHINAGA ; Masahito WATARAI
Journal of the Japanese Association of Rural Medicine 2025;73(5):425-433
		                        		
		                        			
		                        			Even within a hospital, the prognosis after a cardiac arrest is extremely poor if intervention starts only after the event; thus, early recognition and intervention is crucial to reduce inhospital cardiac arrests. This paper aims to assess the results of in-clinic surveys conducted for the implementation of the Rapid Response System (RRS) at our hospital and changes in awareness after awareness initiatives. Excluding the neonatal intensive care unit, all wards were targeted for implementation, with the creation of criteria for requesting the RRS and hospital-wide awareness initiatives. Four items were defined for the request criteria—namely, (1) respiration, (2) circulation, (3) state of consciousness, and (4) others (any concerns)—with a request being warranted if any one of these criteria was met. A pre-awareness survey revealed that respiratory rates were recorded only 6.9% of the time on average, indicating inadequate observation of respiratory rates across all wards. In response to this issue, we announced that respiratory status should be observed at least once a day, which resulted in the recording rate improving to 68.2% after 2 months. Survey results before and after the awareness initiatives among doctors and nurses showed a significant increase in RRS awareness. The percentage of nurses who answered “well aware” or “somewhat aware” increased from 34.8% to 77.6%, and from 63.4% to 88.0% among doctors. However, while the introduction of the RRS was relatively well-received by nurses struggling with on-site responses, some doctors questioned the necessity of the RRS. Upon implementation, it is important to make it known that it is a hospital-wide effort. Simplifying and thoroughly utilizing the request criteria can lead to early recognition of abnormalities. Since it is not easy to gain doctors’ understanding, it is necessary to listen to the needs and requests of each department and patiently continue awareness activities before implementation
		                        		
		                        		
		                        		
		                        	
2.Treatment options for solitary hepatocellular carcinoma ≤5 cm: surgery vs. ablation: a multicenter retrospective study
Kazuya KARIYAMA ; Kazuhiro NOUSO ; Atsushi HIRAOKA ; Hidenori TOYODA ; Toshifumi TADA ; Kunihiko TSUJI ; Toru ISHIKAWA ; Takeshi HATANAKA ; Ei ITOBAYASHI ; Koichi TAKAGUCHI ; Akemi TSUTSUI ; Atsushi NAGANUMA ; Satoshi YASUDA ; Satoru KAKIZAKI ; Akiko WAKUTA ; Shohei SHIOTA ; Masatoshi KUDO ; Takashi KUMADA
Journal of Liver Cancer 2024;24(1):71-80
		                        		
		                        			 Background:
		                        			/Aim: The aim of this study was to compare the therapeutic efficacy of ablation and surgery in solitary hepatocellular carcinoma (HCC) measuring ≤5 cm with a large HCC cohort database. 
		                        		
		                        			Methods:
		                        			The study included consecutive 2,067 patients with solitary HCC who were treated with either ablation (n=1,248) or surgery (n=819). Th e patients were divided into three groups based on the tumor size and compared the outcomes of the two therapies using propensity score matching. 
		                        		
		                        			Results:
		                        			No significant difference in recurrence-free survival (RFS) or overall survival (OS) was found between surgery and ablation groups for tumors measuring ≤2 cm or >2 cm but ≤3 cm. For tumors measuring >3 cm but ≤5 cm, RFS was significantly better with surgery than with ablation (3.6 and 2.0 years, respectively, P=0.0297). However, no significant difference in OS was found between surgery and ablation in this group (6.7 and 6.0 years, respectively, P=0.668). 
		                        		
		                        			Conclusion
		                        			The study suggests that surgery and ablation can be equally used as a treatment for solitary HCC no more than 3 cm in diameter. For HCCs measuring 3-5 cm, the OS was not different between therapies; thus, ablation and less invasive therapy can be considered a treatment option; however, special caution should be taken to prevent recurrence. 
		                        		
		                        		
		                        		
		                        	
3.Different Outcomes in Two Cases of Idiopathic Normal Pressure Hydrocephalus in the Elderly Living Alone Diagnosed by Internists during Hospitalization
Nobuhiro IKEDA ; Tsuneyasu YOSHIDA ; Shigeki YAMADA ; Masatsune ISHIKAWA ; Toru KAMIYA
An Official Journal of the Japan Primary Care Association 2019;42(1):52-57
		                        		
		                        			
		                        			Idiopathic normal pressure hydrocephalus (iNPH) is a disorder observed in elderly patients causing gait disturbance, urinary incontinence and cognitive impairment. Due to the rapidly aging society, the number of patients with iNPH continues to increase yearly. However, iNPH is often overlooked because of its insidious and variable presentation. In the primary care setting, iNPH can be coincidentally discovered by neuroimaging findings, including disproportionately enlarged subarachnoid space hydrocephalus (DESH). We report two cases of iNPH in the elderly living alone that had different outcomes depending upon the availability of neurosurgery specialists. It is essential for primary care physicians to consult neurosurgeons without delay because prompt diagnosis and treatment can improve the patient's quality of life and prolong their duration of living at home.
		                        		
		                        		
		                        		
		                        	
4.A survey of home care provided by hospitals and clinics in an urban area of Japan
Masakatsu Shimizu ; Takuya Shinjo ; Shigeyuki Kobayashi ; Shoji Hamano ; Toru Okano ; Hiroomi Nakamura ; Akihiro Ishikawa ; Masako Sekimoto ; Hiroyuki Makimura ; Akira Honjo ; Kobe Medical Association Home Care Group
Palliative Care Research 2015;10(1):301-305
		                        		
		                        			
		                        			Objective:The aim of this study was to investigate the current status of home care provided by hospitals and clinics in Kobe City. Methods:In July 2013 a survey was mailed to a cross-section of all clinics and hospitals in Kobe City. Results:Questionnaires were sent to 1,589 clinics and hospitals and 899(57%)responded. Regular and urgent home visits by doctors were provided by 50% and 65% of respondents, respectively. End-of-life care for dying patients at home and in nursing homes was provided by 31% and 18% of respondents, respectively. The average time spent on home visits was 2.3±1.7 days per week. Care for cancer patients, participation in national palliative care lectures, and holding a discussion at the admitting hospital before discharge for home care, were performed by 23%, 7.0%, and 6.9% of respondents, respectively. Conclusion:The majority of hospitals and clinics in Kobe City provided home care.
		                        		
		                        		
		                        		
		                        	
5.Factors contributing to the burden of home care for doctors
Takuya Shinjo ; Masakatsu Shimizu ; Shigeyuki Kobayashi ; Shoji Hamano ; Toru Okano ; Hiroomi Nakamura ; Akihiro Ishikawa ; Masako Sekimoto ; Hiroyuki Makimura ; Akira Honjo ; Kobe Medical Association Home Care Group
Palliative Care Research 2014;9(1):107-113
		                        		
		                        			
		                        			Objective: The aim of this study is to explore the factors associated with the burden of home care for doctors. Methods: In July 2013 a survey was mailed to a cross-section of clinics and hospitals in Kobe City. Results: Questionnaires were sent to 1,589 clinics and hospitals and 899 (57%) responded. Of these, data from 807 respondents were available for analysis. The burden of home care was felt to be considerable for 30% and slight for 31% of respondents. Determinants associated with the burden of home care were; 80 years and older doctors (P=0.05), particular medical measures (P=0.036), building links with other medical facility or care staff (P=0.002), and ensuring the sufficient time and staff (P<0.001). Conclusion: The majority of doctors reported a burden associated with home care.
		                        		
		                        		
		                        		
		                        	
6.A Case of Aortic Stenosis Secondary to Bicuspid Aortic Valve Associated with Klippel-Feil Syndrome Treated by Aortic Valve Replacement.
Shigeru Ohki ; Susumu Ishikawa ; Akio Ohtaki ; Toru Takahashi ; Yasushi Satoh ; Tetsuya Koyano ; Toshiharu Yamagishi ; Takashi Ogino ; Satoshi Ohki ; Yasuo Morishita
Japanese Journal of Cardiovascular Surgery 1997;26(3):200-203
		                        		
		                        			
		                        			A 52-year-old male was diagnosed as having aortic stenosis secondary to a bicuspid aortic valve associated with Klippel-Feil syndrome. Aortic valve replacement was successfully performed without any problems in the surgical or anesthesiological management. Only five such cases including ours, who underwent cardiac surgery have been reported. It is possible to perform cardiac surgery for patients with Klippel-Feil syndrome of their cardiac function can be well preserved.
		                        		
		                        		
		                        		
		                        	
7.Long-term Results of Surgical Treatment of Abdominal Aortic Aneurysm.
Satoshi Ohki ; Susumu Ishikawa ; Takashi Ogino ; Akio Ohtaki ; Toru Takahashi ; Yutaka Hasegawa ; Toshiharu Yamagishi ; Syuji Sakata ; Jun Murakami ; Yasuo Morishita
Japanese Journal of Cardiovascular Surgery 1997;26(5):298-301
		                        		
		                        			
		                        			A follow-up study of 98 patients undergoing abdominal aortic aneurysm (AAA) repair for 44 months, ranging 2 to 113 months, revealed no difference in 5-year actuarial survival between patients aged 75 or older and patients aged less than 75. The 5-year actuarial survival of ruptured and nonruptured AAA cases was 469% and 71.2%, respectively (p<0.01). Late deaths after the repair of ruptured AAA were all due to atherosclerotic diseases. During a follow-up period after AAA repair, 9 patients were diagnosed as having malignant diseases with a fatal outcome in 6. Careful attention to atherosclerotic and malignant diseases is indispensable for follow-up management after AAA repair.
		                        		
		                        		
		                        		
		                        	
8.Preoperative Pulmonary Arterial Pressure and Surgical Treatment of Secundum Atrial Septal Defect in Patients over 50 Years of Age.
Yutaka Hasegawa ; Susumu Ishikawa ; Akio Ohtaki ; Toru Takahashi ; Hideaki Ichikawa ; Yasushi Sato ; Tetsuya Koyano ; Masao Suzuki ; Masaaki Takao ; Yasuo Morishita
Japanese Journal of Cardiovascular Surgery 1996;25(5):285-289
		                        		
		                        			
		                        			The preoperative pulmonary arterial pressure of 38 patients aged over 50 undergoing surgical closure of a secundum atrial septal defect was studied. They were divided into three groups according to systolic pulmonary arterial pressure (PAP): Group A (PAP<30mmHg, n=14), Group B (30≤PAP<50mmHg, n=16), and Group C (PAP≥50mmHg, n=8). The mean age of group C patients was older than that of group A patients. With higher PAP, the Pp/Ps, Rp/Rs and cardiothoracic ratios increased, atrial fibrillation and heart failure (NYHA≥2) were more frequent, and PaO2 levels declined. There were no differences in left to right shunt ratio and Qp/Qs among the three groups. The PAP and Rp/Rs were under 70mmHg and 0.30, respectively in all patients. High pulmonary blood flow seems to be the cause of pulmonary hypertension in most elderly patients because PAP and Rp/Rs decreased after surgery in all groups. Findings of cardiomegaly and heart failure also improved after surgery. Surgical intervention is recommended even in elderly patients with a ASD.
		                        		
		                        		
		                        		
		                        	
9.A Case of Coronary Ostial Stenosis with Aortic Regurgitation Due to Syphilitic Aortitis.
Yasushi Sato ; Susumu Ishikawa ; Akio Ohtaki ; Kazuhiro Sakata ; Yoshimi Otani ; Toru Takahashi ; Ichiro Yoshida ; Yasuo Morishita
Japanese Journal of Cardiovascular Surgery 1995;24(3):175-177
		                        		
		                        			
		                        			A 50-year-old man was diagnosed as having aortic valve insufficiency, complete occlusion of the right coronary artery and 75% stenosis of the left main trunk due to syphilitic aortitis. Aortic valve replacement and coronary artery bypass grafting to three vessels were successfully performed. The selection of surgical procedures for the coronary lesion with syphilitic aortitis should be made carefully, since the progression of aortic root inflammation in the acute phase and the development of atherosclerotic changes are not preventable in the future. It is most important to select effective and safe surgical interventions, especially for patients with such a low cardiac function as our patient.
		                        		
		                        		
		                        		
		                        	
10.Total Removal of a Contaminated Pacemaker under Cardiopulmonary Bypass in a Case of MRSA Septicemia.
Yutaka Hasegawa ; Susumu Ishikawa ; Akio Otaki ; Yasushi Sato ; Kazuhiro Sakata ; Toru Takahashi ; Motoi Kano ; Tetsuya Koyano ; Masao Suzuki ; Yasuo Morishita
Japanese Journal of Cardiovascular Surgery 1995;24(5):347-350
		                        		
		                        			
		                        			A 78-year-old man underwent successful removal of a contaminated pacemaker in a case of methicillin-resistant Staphylococcus aureus (MRSA) septicemia. Septicemia was due to a subcutaneous abscess at the site of old cut electrodes. Following debridement of the infected pacemaker pocket, residual leads and the pacemaker system were removed under cardiopulmonary bypass. Bacterial examination of arterial blood and vegetation attached to the leads showed septicemia caused by MRSA. After the operation, antibiotic therapy with vancomycin, arbekacin and minocycline was performed for several weeks. His postoperative course was uneventful without the recurrence of infection. In cases of pacemaker contamination, with septicemia, total removal of the pacemaker system and adequate antibiotic therapy are necessary.
		                        		
		                        		
		                        		
		                        	
            

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