1.Atypical Toxocara canis-Induced Hepatic Visceral Larva Migrans: Diagnostic Challenges and Literature Review
Tien Manh HUYNH ; Khanh Quoc Le TRAN ; Trung Hoang DINH ; Man Minh VO ; Thong Quang PHAM ; Thong Duy VO
The Korean Journal of Gastroenterology 2024;83(6):247-252
Toxocariasis, a zoonotic infection transmitted by Toxocara canis (from dogs) and Toxocara cati (from cats) larvae, poses rare but severe risks to humans. We present a case of hepatic visceral larva migrans (VLM) caused by Toxocara canis in a 21-year-old male with a history of close contact with a pet dog. Initial symptoms and imaging findings mimicked a pyogenic liver abscess. The initial laboratory investigations revealed neutrophilia and elevated levels of IgE. Despite broad-spectrum antibiotics, persistent fever prompted further investigation. Subsequent serological testing for Toxocara antibodies and histopathological analysis of liver tissue demonstrating eosinophil infiltrates and Charcot-Leyden crystals led to a confirmed diagnosis of a liver abscess caused by Toxocara canis. Serological testing for Toxocara antibodies and histopathological analysis of liver tissue confirmed a Toxocara canis-induced liver abscess. Albendazole treatment yielded significant clinical improvement. This case highlights the necessity of considering toxocariasis in liver abscess differentials, particularly in high-seroprevalence regions like Vietnam. Relying solely on serological tests may be insufficient, emphasizing the need for corroborative evidence, including invasive procedures like liver biopsy, for accurate hepatic toxocariasis diagnosis.
2.Suicidal ideation and adverse experiences among adolescents with their separated/divorced parents in Hue city
Thi Tra My TRAN ; Binh Thang TRAN ; Minh Tam NGUYEN ; Nu Hong Duc VO ; Van Thong NGUYEN ; Ngo Bao Khuyen NGUYEN ; Thi Thu Ha PHAM ; Uyen Phuong HO ; Hoang Linh VO ; Thi Thu Tham LUONG ; Tuan Anh HOANG ; Cao Khoa DANG ; Thanh Gia NGUYEN ; Minh Tu NGUYEN
Hue Journal of Medicine and Pharmacy 2023;13(6):25-
Background: Suicide continues to be a leading cause of death worldwide. Recently, more than 45,000 children in the age group of 10 to 19 years died by suicide, making it the second leading cause of death in the age group of 15 to 19, surpassed only by traffic accidents, tuberculosis, and fighting. Objective: To determine the prevalence of suicidal ideation among adolescents whose parents are separated/divorced; and to explore the factors associated with suicidal ideation and describe adverse experiences among adolescents. Methods: A cross-sectional descriptive study was conducted in 309 adolescents with separated/separated parents in Hue City. Data was collected through direct interviews using a structured questionnaire. Suicidal ideation was defined as the presence of thoughts or plans related to suicide within the last 12 months. Multivariate logistic regression was applied to identify factors associated with suicidal ideation in adolescents with separated/ separated parents. Results: The study found that 15.5% (95% CI:11.7 - 20.1) of adolescents with separated /separated parents reported experiencing suicidal thoughts, in which men accounted 8.4% (95% CI:5.6 – 11.2) and women accounted 7.1% (95% CI:4.5 - 10.6). Several factors were identified as increasing the risk of suicidal ideation, including alcohol use (OR = 3.24; 95% CI:1.42 - 7.42), hyperactivity/inattention (OR = 4.96; 95% CI:1.58 - 15.605), and a poor quality of family relationships (OR = 4.82; 95% CI:1.26 - 18.50). On the contrary, certain factors were found to reduce the risk, including being in the 14-15 age group of 14-15 (OR = 0.26; 95% CI:0.10 - 0.69) and participating in physical activity (OR = 0.44; 95% CI:0.21 – 0.94). Conclusions: The research highlights a significant percentage of adolescents with separated / divided parents who experience suicidal ideation. Therefore, it is imperative for families, schools, and society to develop comprehensive strategies to monitor and address various risky behaviours among students simultaneously.
4.Rare Complication of Strongyloidiasis in Vietnam: A Case of Venous Thromboembolism and Duodenal Obstruction
Tien Huynh MANH ; Khanh Quoc Le TRAN ; Phat Tan HO ; Man Minh VO ; Thong Quang PHAM ; Thong Duy VO
The Korean Journal of Gastroenterology 2023;81(6):270-275
Strongyloidiasis, a chronic helminth infection caused by the parasitic nematode Strongyloides stercoralis, has various clinical manifestations. Although rare, duodenal obstructions and venous thromboembolism are possible complications of strongyloidiasis.This paper presents the case of a 47-year-old Vietnamese male with a history of right lower limb edema, anorexia, nausea, vomiting, diarrhea, and abdominal discomfort lasting for four months. Venous Doppler ultrasound detected a thrombus in the right femoral vein, while an abdominal CT scan revealed a mass lesion suggestive of a lower bile duct tumor. Esophageogastroduodenoscopy showed a friable duodenal cap mucosa with multiple ulcers and edematous mucosa of the second part of the duodenum that caused a partial lumen obstruction. The final histological examination of the biopsy specimen revealed chronic duodenitis with larvae consistent with Strongyloides stercoralis. The patient was treated with Ivermectin for two weeks and anticoagulation therapy for three months. After treatment and a six-month follow-up, the patient's gastrointestinal symptoms and leg swelling resolved completely. This is the first documented case of a patient in Vietnam with strongyloidiasis who presented with venous thromboembolism and duodenal obstruction. (Korean J Gastroenterol 2023;81:270-275)
5.Estimating the effectiveness of nimodipin in treatment of children with intracranial hemorrhage
Huong Thi Thanh Nguyen ; Ung Thi Ninh ; Thong Minh Pham ; Huyen Thi Thanh Ho
Journal of Medical Research 2007;55(6):58-64
Background:Cerebral vasospasm is a proved reaction and nimodipin revolutionised the treatment of subarrachnoid hemorrhage in adult. However, the effectiveness of Nimodipin in cerebral vasospasm remained controversial in intracranial hemorrhage (lCH) in children. Objectives:This study aims to estimate the effectiveness of nimodipin in treatment of children with intracranial hemorrhage.Subjects and method:A descriptive, prospective study was conducted on all children patients diagnosed intracranial hemorrhage and treated at Neurology department of National Hospital for Pediatric, Vietnam from 2004 to June 2007. They applied the Transcranial Doppler sonography (TCD) in diagnosis of vasospasm in intracranial hemorrhage in children and follow-up the evolution after treatment with nimodipin. Results:The results showed that cerebral vasospasm with hight resistance index (RI) on TCD (RI = 0.78 \xb1 0.08) and cerebral ischemie with low systolic velocity (Vs = 68 \xb1 12.2 crn/s) and hight pulsality index (PI = 1.4 \xb1 0.13) were observed in 100% of cases after 3 days with ICH. Nimodipine improved clinical status (71.2%) and CT scan (52%), also RI, PI, Vs returned to normal when used nimodipin within 7 days of ICH. Conclusion: The treatment method for intracranial hemorrhage with nimodipin supplement had proved to have initial effecacy in comparison with traditional method.
Intracranial Hemorrhages/ therapy
;
Nimodipine/ therapeutic use
;
Infant
6.Evaluating clinical experience from a case of hepatocellular carcinoma with combinated therapy of transarterial chemoembolization and percutaneousethanol injection afterward emerging metatasis caused by fine needle aspiration cytology
Long Cong Nguyen ; Truong Xuan Bui ; Thong Minh Pham ; Ho Thi Thu Pham ; Hung Quoc Nghiem ; Phuong Minh Tran ; Long Van Dao ; Trach Khanh Nguyen
Journal of Medical Research 2007;47(2):69-73
Background: Hepatocellular carcinoma (HCC) is the most common primary hepatic tumor and one of the most common cancers worldwide. HCC is a primary malignancy of hepatocellular origin. Objectives:The aim of study is to combinate therapy of transarterial chemoembolization and percutaneousethanol injection afterward emerging metatasis caused by fine needle aspiration cytology. Subjects and method: A 50 years old male patient with hepatocellular carcinoma having a diameter of tumor more than 5 cm was treated by combination of transarterial chemoembolization and percutaneous ethanol injection from December 2000. Results & Conclusion: Results of study showed that: Transarterial chemoembolization and percutaneous ethanol injection are the two of non-surgical methods for treatment of hepatocellular carcinoma which are most commonly available in applied clinical activities at present. Up to now, the patient's life expectancy after therapy is more than 6 years that means the result of treatment is very good. However, the emerging metatasis into the anterior-right-Iower chest wall that was caused by fine needle aspiration cytology should be reviewed for further evaluating clinical experience, especially in cases with quite clear imaging features of untrasonography and significantly elevated AFP level higher than 200 ng/rnl.
Carcinoma
;
Hepatocellular/ pathology
;
therapy
7.To evaluate the results of treatment of liver cell carcinoma by method of chemical plug of liver artery on 134 patients at Bach Mai Hospital
Journal of Medical Research 2004;27(1):99-104
The study was performed on 134 patients of primary liver cell cancer, treated through 294 episodes of chemical plug using lipiodol through the arteries, in order to evaluate the efficacy of treatment by the method of chemical plug of liver artery and to give some imaging diagnostic factors related to the effect of treatment. Results showed that all cases were intervented favorably, without death by the technique. In majority of cases, chemical improvements were notified (weight gain, pain relief in the liver...) > 6 months survival reported in 82.35%, > 12 months survival 48.24%, mean survival duration 16 months. In comparison with palliative treatment, the method of liver artery chemical plug gave higher efficacy
Liver Neoplasms
;
Therapeutics
;
Arteries
;
liver
8.Preliminary results of intracranial vascular disease with interventional endovascular therapy
Journal of Practical Medicine 2003;458(8):36-38
Apply interventional endovascular therapy in 100 patients with intracranical aneurysms between 24 and 69 years old of age from 2001 May to 2003 February. All patients underwent angiography by Seldinger's technique, then embolized by GDC coils, Cook coils or balloon. Results: success: 9 cases, fail: 1 case because of sinuous carotid arteries so that couldn't catheterization. Aneurysm embolization is efficient method. Saccular aneurysms with median size of 8-14mm are indicated embolization. Giant aneurysms are treated by embolization of carotid arteries after tested given good results
Cerebrovascular Disorders
;
Aneurysm
;
Diseases
9.Some features of the images of the malformations of brain arteries and venae and preliminary results of treatment bembolus obturating
Journal of Practical Medicine 2003;459(9):28-30
The study carries on 35 patients with intracranial arteriovenous malformation (MAV) diagnosed at faculty of neurology of Bach Mai hospital. These patients were treated by method embolization in intravascular. The injury only MVA found usually on young with 80% < 40 years old, and on man more than woman. The injury MVA of supratentorial is 91.43%, local function is 82.86%, fed by peduncle of arteria is 74.29%, reflux vein of superficial corter vein is 57.15%, return sinus vein doc tren or through vein deep purely or combined is 42.85%. The result of embolization at first step at level good is 77.4%, medial 17.14%, and dealth is 5.72%. This is independent treatment method and can also supported for surgery and surgery X ray locative
Intracranial Arteriovenous Malformations
;
Brain
;
Embolism
10.Role of colour ultrasonography in detection of renal artery stenosis
Journal of Practical Medicine 2002;435(11):34-36
The study was conducted from January 1996 to March 1998 in B¹ch Mai Hospital. Participants were 100 hypertensive patients who have suspected renal artery stenosis after screening using clinical examination. Age of participants ranged from 9 to 50. All participants underwent colour ultrasonography and measurements are evaluated. Results showed that among 18 renal arteries of 9 patients, who received ultrasonography and angiography, 10 arteries were stenosed or occluded. 1 renal artery had suspected stenosis showed in ultrasonography, but not in angiography. So Doppler ultrasonography produced 1 false positive result, 10 true positive results, 7 true negative results and none false negative. This procedure gave high 100% of sensivity, 87.5% of speciality, positive prediction value is 90.9%, negative prediction value is 100%. Doppler ultrasonography can be used for post-operative examination and for patient following-up
Renal Artery Obstruction
;
Ultrasonography

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