1.Assessment of rational use of antibiotics among hospitalized pregnant women at the National Center for Maternal and Child Health
Oyungerel V ; ; Temuulen T ; Sosorbaram A ; Purevsuren S ; Tungalag B
Mongolian Journal of Health Sciences 2025;90(6):178-183
Background:
Pregnancy induces multiple physiological, metabolic, and immunological alterations that increase susceptibility to infections, often necessitating antibiotic therapy. Evaluating the rational use of antibiotics among pregnant
women is crucial for optimizing antimicrobial stewardship at the hospital level, improving clinical pharmacy services,
and reducing the risk of antimicrobial resistance.
Aim:
To assess the rational use of antibiotics, including indication, selection, dosage, and treatment duration—among
hospitalized pregnant women in the Department of High-Risk Pregnancy and the Department of Preterm Birth at the
National Center for Maternal and Child Health.
Materials and Methods:
A retrospective study was conducted using a specifically designed data collection form to assess
antibiotic use among inpatients at the National Center for Maternal and Child Health. Descriptive statistical analyses were
performed using SPSS version 29.0.
Results:
A total of 348 pregnant inpatients were included, with a mean age of 31.6 ± 6.9 years. The mean length of hospital stay was significantly longer in the Department of Preterm Birth (12.5 ± 5.0 days) compared to the Department of
High-Risk Pregnancy (5.9 ± 2.0 days; p < 0.001). The indications for antibiotic use were therapeutic in 39.1%, prophylactic in 33.0%, and unspecified in 21.3% of cases. The most frequently prescribed antibiotic regimen was a combination
of β-lactams and metronidazole (29%). While the dosing of cefazolin and cefotaxime was largely appropriate, notable
dosing discrepancies were observed in the dosing of ampicillin and azithromycin. Based on the U.S. FDA pregnancy risk
classification, among a total of 762 antibiotic prescriptions, 87.0% belonged to category B, 8.8% to category C, and 4.2%
to category D, with no significant variation across trimesters (p = 0.695).
Conclusion
The assessment of antibiotic use among hospitalized pregnant women at the National Center for Maternal
and Child Health revealed that 39.1% of the prescriptions were therapeutic, 33.0% were prophylactic, and 21.3% lacked
a clear indication for use. β-lactam antibiotics were the most commonly used agents, frequently combined with metronidazole. Based on the FDA classification system, 87% of the prescribed antibiotics belonged to category B, 8.8% to
category C, and 4.2% to category D. These findings indicate inappropriate antibiotic use and insufficient implementation
of antimicrobial susceptibility testing. Therefore, strict adherence to antibiotic stewardship programs and strengthening
of clinical pharmacy services are necessary to improve antibiotic use practices.
2.Healthy live guidance based on human characteristic types by traditional Mongolian medicine
Tuul Kh ; Munkhdelger D ; Sosorbaram L ; Lkhagvasuren Ts
Mongolian Pharmacy and Pharmacology 2018;13(2):14-17
Introduction:
Traditional Mongolian medicine contents a whole idea of preventive medicine.
Traditional Mongolian medicine main theory is “Rlung-Mkhris-Badgan” which is composed human
body. These elements confirm human healthy during metabolite balance but when any of these
lacks or exists in an excessive amount, then there is an illness. Understanding on the theory “Rlung-Mkhris-Badgan” by modern medicine there are called cell universal regulation system.[1] A striking
feature of metabolism is the similarity of the basic metabolic pathways and components of “Rlung-Mkhris-Badgan” even vastly different metabolic pathways. Human has own Rlung-Mkhris Badgan`s
portion differently when they were born, during all life must obey their attribute manner. There are
seven individualities which expressed human characters.
Furthermore in traditional Mongolian medicine have richness experience of concerning with
three elements unbalanced time to come disease early diagnosis and remedy them effectively. Accordingly organic body must adaption four seasons` biological accommodation and follow up four
seasons` suitable food technology and climate condition.
Purpose:
1. To determine human characteristic types by traditional Mongolian medicine main theory.
2. To suggest healthy live advice for people who participate randomized in preventive medical examination by used modern and traditional medical diagnostic methods.
Method:
Biomedicine and Clinical Pharmacy Department doctor teachers were organized “Healthy
life starts every day right habit” topic preventive medical examination for all students of Mongolian
University of Pharmaceutical Sciences 09-29 days of September, 2016. Participant by diagnosed
medical basic physical examination methods and filled out questionnaire in human characteristics
based traditional Mongolian medicine main theory.
Results:
There had 513 participants, 29 of them were “rlung” characteristic personality, 26 of
“mkhris” characteristic personality, 22 of them “badgan” characteristic personality, 163 of them “rlung
and mkhris” combined characteristics, 118 of them “rlung and badgan” combined characteristics”, 68
of them “Badgan and Mkhris” combined characteristics, 87 of them were composite characteristic
personalities.
Conclusion
1. Determined 85% of participants are respectively combined and composed types of characteristic personalities, and these participants supposed to be better metabolism balance. Determined 15% of
participants are one element dominantly personalities.
2. We made a Healthy Life Guidance depending on human characteristics.
3.Acute hepatitis A, B and C but not D is still prevalent in Mongolia: a time trend analysis.
Oidov BAATARKHUU ; Hye Won LEE ; Jacob GEORGE ; Dashchirev MUNKH-ORSHIKH ; Baasankhuu ENKHTUVSHIN ; Sosorbaram ARIUNAA ; Mohammed ESLAM ; Sang Hoon AHN ; Kwang Hyub HAN ; Do Young KIM
Clinical and Molecular Hepatology 2017;23(2):147-153
BACKGROUND/AIMS: Mongolia has one of the highest hepatitis A, C, B and D infection incidences worldwide. We sought to investigate changes in the proportion of acute viral hepatitis types in Mongolia over the last decade. METHODS: The cohort comprised 546 consecutive patients clinically diagnosed with acute viral hepatitis from January 2012 to December 2014 in Ulaanbaatar Hospital, Mongolia. A time trend analysis investigating the change in proportion of acute hepatitis A virus, hepatitis C virus (HCV), hepatitis B virus (HBV) and hepatitis delta virus (HDV) infection among the cohort with respect to a previous published study was undertaken. RESULTS: Acute hepatitis A, B and C was diagnosed in 50.9%, 26.2% and 6.0% of the cohort. Notably, 16.8% of the cohort had a dual infection. The etiologies of acute viral hepatitis were varied by age groups. The most common cause of acute viral hepatitis among 2-19 year olds was hepatitis A, HBV and superinfection with HDV among 20-40 year olds, and HCV among 40-49 year olds. Patients with more than one hepatitis virus infection were significantly older, more likely to be male and had a higher prevalence of all risk factors for disease acquisition. These patients also had more severe liver disease at presentation compared to those with mono-infection. CONCLUSIONS: Acute viral hepatitis is still prevalent in Mongolia. Thus, the need for proper infection control is increasing in this country.
Cohort Studies
;
Hepacivirus
;
Hepatitis A virus
;
Hepatitis A*
;
Hepatitis B
;
Hepatitis B virus
;
Hepatitis C
;
Hepatitis D
;
Hepatitis Delta Virus
;
Hepatitis Viruses
;
Hepatitis*
;
Humans
;
Incidence
;
Infection Control
;
Liver Diseases
;
Male
;
Mongolia*
;
Prevalence
;
Risk Factors
;
Superinfection

Result Analysis
Print
Save
E-mail