1.Whole-genome sequencing of SARS-CoV-2 from residual viral RNA present on positive rapid antigen test kits for genomic surveillance
Mohd Ishtiaq Anasir ; Khayri Kamel ; Nor Malizza G Adypatti ; Mohammad Syafiq Jamaluddin ; Farah Amira Ahmad ; Siti Nurhidayah Norhisham ; Muhammad Zulfazli Mohamad Sukri ; Nur Rafiqah Rosli ; Siti Norazrina Saif ; Nurul Izzati Basarudin ; Mohamad Azzam-Sayuti ; Akmal Hayat Abdul Karim ; Mahirah Kamil Puat ; Ravindran Thayan ; Rozainanee Mohd Zain
Western Pacific Surveillance and Response 2025;16(1):06-11
This report describes an approach to recover SARS-CoV-2 RNA from rapid antigen test kit (RTK-antigen) cassettes for whole-genome sequencing (WGS). RNA samples were recovered from 33 RTK-antigen cassettes for WGS, with 18 samples achieving more than 80% genome coverage. This work provides a proof-of-concept that positive RTK-antigen cassettes can be safely transported, stored and subjected to WGS, enabling swift identification of circulating variants.
2.Estimating the impact of the COVID-19 pandemic on infectious disease notifications in Klang district, Malaysia, 2020–2022
Vivek Jason Jayaraj ; Diane Woei-Quan Chong ; Faridah Binti Jafri ; Nur Adibah Binti Mat Saruan ; Gurpreet Kaur Karpal Singh ; Ravinkanth Perumal ; Shakirah Binti Jamaludin ; Juvina Binti Mohd Janurudin ; Siti Rohana Binti Saad
Western Pacific Surveillance and Response 2025;16(1):40-48
Objective: The COVID-19 pandemic disrupted disease surveillance systems globally, leading to reduced notifications of other infectious diseases. This study aims to estimate the impact of the COVID-19 pandemic on the infectious disease surveillance system in Klang district, Selangor state, Malaysia.
Methods: Data on notifiable diseases from 2014 to 2022 were sourced from the Klang District Health Office. The 11 diseases with more than 100 notifications each were included in the study. For these 11 diseases, a negative binomial regression model was used to explore the effect of the pandemic on case notifications and registrations by year, and a quasi-Poisson regression model was used to explore the changes by week.
Results: The results showed a reduction in the number of notifications and registrations for all 11 diseases combined during the pandemic compared with previous years. Changes between expected and observed notifications by week were heterogeneous across the diseases.
Discussion: These findings suggest that restrictive public health and social measures in Klang district may have impacted the transmission of other infectious diseases during the COVID-19 pandemic. The differential impact of the pandemic on disease notifications and reporting highlights the large ancillary effects of restrictive public health and social measures and the importance of building resilience into infectious disease surveillance systems.
3.Co-occurrence of Frailty, Possible Sarcopenia, and Malnutrition in Community-Dwelling Older Outpatients: A Multicentre Observational Study
Siti SETIATI ; Kuntjoro HARIMURTI ; Ika FITRIANA ; Noto DWIMARTUTIE ; Rahmi ISTANTI ; Muhammad Khifzhon AZWAR ; I Gusti Putu Suka ARYANA ; Sri SUNARTI ; Agus SUDARSO ; Dina Aprillia ARIESTINE ; Lazuardhi DWIPA ; Novira WIDAJANTI ; Nur RIVIATI ; Roza MULYANA ; Rensa RENSA ; Yudo Murti MUPANGATI ; Fatichati BUDININGSIH ; Nina Kemala SARI
Annals of Geriatric Medicine and Research 2025;29(1):91-101
Background:
The co-occurrence of frailty, sarcopenia, and malnutrition was well studied in inpatient and nursing home settings, which was associated with higher risk of all-cause mortality. Multicentre data in community-dwelling outpatient setting were lacking. We aimed to find the prevalence of frailty, possible sarcopenia and malnutrition, their overlap and the associated factors in community-dwelling older outpatients.
Methods:
We collected data from community-dwelling outpatients aged ≥60 years in Indonesian geriatric care centres to conduct this cross-sectional study with bivariate and multivariable analyses. Frailty, possible sarcopenia, and malnutrition diagnoses were based on FRAIL scale, Asian Working Group for Sarcopenia 2019 consensus, and Mini Nutritional Assessment Short Form, respectively.
Results:
The prevalence of frailty, possible sarcopenia, and malnutrition in community-dwelling older outpatients were 13.6%, 45.5%, and 5.3%, respectively. The prevalence of co-occurrence of frailty, possible sarcopenia and malnutrition was 3.3%. It was associated with transient ischemic attack (TIA) and cerebrovascular accident (odds ratio [OR]=5.53, 95% confidence interval [CI] 1.48–20.61), cognitive impairment (OR=3.70, 95% CI 1.21–11.31), and dependent functional capacity (OR=11.62, 95% CI 3.38–39.99). Overlap of three evaluated syndromes was found in 24.1%, 7.2%, and 61.3% of subjects with frailty, possible sarcopenia, and malnutrition, respectively. It was characterized by a substantial proportion of female sex, older adults with low educational attainment, diabetes mellitus, hypertension, cognitive impairment, multimorbidity, and dependent functional status.
Conclusion
Approximately 1 in 30 community-dwelling older outpatients had overlapping frailty, possible sarcopenia, and malnutrition. The condition is associated with TIA and cerebrovascular accident, cognitive impairment, and dependent functional capacity. Standardized screening in community-dwelling older population is necessary.
4.Co-occurrence of Frailty, Possible Sarcopenia, and Malnutrition in Community-Dwelling Older Outpatients: A Multicentre Observational Study
Siti SETIATI ; Kuntjoro HARIMURTI ; Ika FITRIANA ; Noto DWIMARTUTIE ; Rahmi ISTANTI ; Muhammad Khifzhon AZWAR ; I Gusti Putu Suka ARYANA ; Sri SUNARTI ; Agus SUDARSO ; Dina Aprillia ARIESTINE ; Lazuardhi DWIPA ; Novira WIDAJANTI ; Nur RIVIATI ; Roza MULYANA ; Rensa RENSA ; Yudo Murti MUPANGATI ; Fatichati BUDININGSIH ; Nina Kemala SARI
Annals of Geriatric Medicine and Research 2025;29(1):91-101
Background:
The co-occurrence of frailty, sarcopenia, and malnutrition was well studied in inpatient and nursing home settings, which was associated with higher risk of all-cause mortality. Multicentre data in community-dwelling outpatient setting were lacking. We aimed to find the prevalence of frailty, possible sarcopenia and malnutrition, their overlap and the associated factors in community-dwelling older outpatients.
Methods:
We collected data from community-dwelling outpatients aged ≥60 years in Indonesian geriatric care centres to conduct this cross-sectional study with bivariate and multivariable analyses. Frailty, possible sarcopenia, and malnutrition diagnoses were based on FRAIL scale, Asian Working Group for Sarcopenia 2019 consensus, and Mini Nutritional Assessment Short Form, respectively.
Results:
The prevalence of frailty, possible sarcopenia, and malnutrition in community-dwelling older outpatients were 13.6%, 45.5%, and 5.3%, respectively. The prevalence of co-occurrence of frailty, possible sarcopenia and malnutrition was 3.3%. It was associated with transient ischemic attack (TIA) and cerebrovascular accident (odds ratio [OR]=5.53, 95% confidence interval [CI] 1.48–20.61), cognitive impairment (OR=3.70, 95% CI 1.21–11.31), and dependent functional capacity (OR=11.62, 95% CI 3.38–39.99). Overlap of three evaluated syndromes was found in 24.1%, 7.2%, and 61.3% of subjects with frailty, possible sarcopenia, and malnutrition, respectively. It was characterized by a substantial proportion of female sex, older adults with low educational attainment, diabetes mellitus, hypertension, cognitive impairment, multimorbidity, and dependent functional status.
Conclusion
Approximately 1 in 30 community-dwelling older outpatients had overlapping frailty, possible sarcopenia, and malnutrition. The condition is associated with TIA and cerebrovascular accident, cognitive impairment, and dependent functional capacity. Standardized screening in community-dwelling older population is necessary.
5.Co-occurrence of Frailty, Possible Sarcopenia, and Malnutrition in Community-Dwelling Older Outpatients: A Multicentre Observational Study
Siti SETIATI ; Kuntjoro HARIMURTI ; Ika FITRIANA ; Noto DWIMARTUTIE ; Rahmi ISTANTI ; Muhammad Khifzhon AZWAR ; I Gusti Putu Suka ARYANA ; Sri SUNARTI ; Agus SUDARSO ; Dina Aprillia ARIESTINE ; Lazuardhi DWIPA ; Novira WIDAJANTI ; Nur RIVIATI ; Roza MULYANA ; Rensa RENSA ; Yudo Murti MUPANGATI ; Fatichati BUDININGSIH ; Nina Kemala SARI
Annals of Geriatric Medicine and Research 2025;29(1):91-101
Background:
The co-occurrence of frailty, sarcopenia, and malnutrition was well studied in inpatient and nursing home settings, which was associated with higher risk of all-cause mortality. Multicentre data in community-dwelling outpatient setting were lacking. We aimed to find the prevalence of frailty, possible sarcopenia and malnutrition, their overlap and the associated factors in community-dwelling older outpatients.
Methods:
We collected data from community-dwelling outpatients aged ≥60 years in Indonesian geriatric care centres to conduct this cross-sectional study with bivariate and multivariable analyses. Frailty, possible sarcopenia, and malnutrition diagnoses were based on FRAIL scale, Asian Working Group for Sarcopenia 2019 consensus, and Mini Nutritional Assessment Short Form, respectively.
Results:
The prevalence of frailty, possible sarcopenia, and malnutrition in community-dwelling older outpatients were 13.6%, 45.5%, and 5.3%, respectively. The prevalence of co-occurrence of frailty, possible sarcopenia and malnutrition was 3.3%. It was associated with transient ischemic attack (TIA) and cerebrovascular accident (odds ratio [OR]=5.53, 95% confidence interval [CI] 1.48–20.61), cognitive impairment (OR=3.70, 95% CI 1.21–11.31), and dependent functional capacity (OR=11.62, 95% CI 3.38–39.99). Overlap of three evaluated syndromes was found in 24.1%, 7.2%, and 61.3% of subjects with frailty, possible sarcopenia, and malnutrition, respectively. It was characterized by a substantial proportion of female sex, older adults with low educational attainment, diabetes mellitus, hypertension, cognitive impairment, multimorbidity, and dependent functional status.
Conclusion
Approximately 1 in 30 community-dwelling older outpatients had overlapping frailty, possible sarcopenia, and malnutrition. The condition is associated with TIA and cerebrovascular accident, cognitive impairment, and dependent functional capacity. Standardized screening in community-dwelling older population is necessary.
6.Evaluation of Occupational Radiation Exposure to Undergraduate Students During Clinical Training in Radiology Department
Muhammad Safwan Ahmad Fadzil1 ; Nurul Elni Md Yusof1 ; Wan Anwah Filzah Wan Anuar1 ; Siti Hajar Zuber1 ; Rozilawati Ahmad1 ; Abdul Khaliq Ahmad Saparuddin1 ; Norhafidzah Mohamed Sharif1 ; Khadijah Mohamad Nasir1 ; Nani Adilah Suhaimi1 ; Noraini Ahmad Wahid1 ; Nur Khalis Sukiman1 ; Ahmad Bazlie Abdul Kadir2
Malaysian Journal of Medicine and Health Sciences 2025;21(No. 1):10-17
Introduction: Assessing radiation exposure is a vital step in determining the potential health risks associated with
radiation and identifying the necessity for protective measures. The study assesses the occupational radiation dose
encountered by undergraduate students specializing in diagnostic imaging and radiotherapy (DIR) during their clinical training in the radiology department. Materials and methods: An analysis was conducted to compare individual
exposure doses with the dose limits established by the International Commission on Radiological Protection (ICRP),
concurrently assessing the variations in mean effective doses among distinct student cohorts. Optically stimulated luminescence dosimeters (OSLD) were employed to monitor 143 students across five cohorts from 2017 to 2022. The
electronic Secondary Standard Dosimetry Laboratory (e-SSDL) information security management system tracked the
deep (Hp(10)) and shallow (Hp(0.07)) dose equivalents of DIR students. Results: The mean values for accumulated
Hp(10) and Hp(0.07) were found to be 0.51 and 0.50 mSv, respectively, averaged over 800 hours of clinical training.
The highest recorded exposure was 1.30 mSv, signifying that the radiation exposure experienced by DIR students
was well below the threshold. The mean annual effective radiation dose per student amounted to 0.17 mSv. Small
but significant difference (p < 0.001) in the radiation exposure between five cohorts was observed with increments
over a 5-year period. Conclusion: The students' radiation dose was notably below the ICRP dose limit of 6 mSv/
year designated for trainees. These results indicate the efficacy of the existing radiation protection measures during
clinical training, reducing the likelihood of overexposure
7.Knowledge and Practice in Preventing Fall Among Obstetrics Patients in State Hospital in Terengganu
Siti Hajar Muda ; Wan Nur Hafsah Wan Lokman
International Journal of Public Health Research 2025;15(1):2167-2173
Falls during pregnancy are a typical reason for minor injuries, and they can occasionally be dangerous for both the mother and the unborn child. This study is designed to identify the knowledge and practice in preventing falls among obstetrics patients in Hospital Sultanah Nur Zahirah. This cross-sectional study used a self-reported questionnaire involving women admitted and delivered at a state hospital between October to December 2022. The Pearson Chi-Square test in SPSS software was used to examine associations between sociodemographic characteristics and variables of interest. Overall, 350 postnatal women were selected as the subjects. The mean age of the women was 30.41 ± 5.4 (range: 19-44) years old. Most of the respondents were in parity 2 to 4 (56.3%). Fifty-seven women (16.3%) reported falling at least once during the index pregnancy. The mean score for knowledge was 12.30 ± 3.72, with 16.6% having good knowledge and the mean score for practice was 7.24 ± 4.23, 25.4% of them were having good practice. The women’s knowledge of preventing falls during pregnancy was predicted by their age (χ2 = 19.73, p = <0.05), education (χ2 = 21.582, p = <0.05) and parity (χ2 = 15.208, p = <0.05). The practice of the women about preventing falls was significantly poorer amongst the women who were younger (χ2 = 23.434, p = <0.05), less family income (χ2 = 17.95, p = <0.05), and had no more than a secondary education (χ2 = 14.88, p = <0.05). The findings of the study revealed that age, level of education and parity is associated with knowledge of women in preventing falls. While age, level of education and family income are associated with practice in preventing falls. Hence, awareness campaigns using effective risk communication models are advised to increase knowledge and good practice among pregnant women
8.Ergonomic Risk Factors and Job Performance of Electronic Employee in Malaysia
Nur Alia Syuhada Mohd Nizam ; Siti Nurhafizah Saleeza Ramlee
Malaysian Journal of Medicine and Health Sciences 2024;20(No.1):112-118
Introduction: Ergonomics is the scientific study of the interactions between humans and other elements of a system
to improve human well-being and overall system performance. In larger scope ergonomics examines human behavioral, psychological, and physiological capabilities and limitations. It has given a huge impact on the workers comfort which directly affects the work efficiency and productivity. In Malaysia, the electronics industry is the leading
industry in the manufacturing sector and one of the largest employers. This study was conducted to examine the relationship between ergonomics factors and job performance among employees in electronics industry. Material and
Method: A total of 155 employees in electronic industry were involved as respondents in this study. A cross-sectional
study was conducted using self-administered questionnaires consisting of sections on physical ergonomics, cognitive
ergonomics, and organizational ergonomics and job performance. The data were analysed using SPSS version 25,
and descriptive statistics, person correlation and multiple liner regressions were used to identify the factors associated with job performance. Results: The findings showed that there is a significant relationship between ergonomics
factors (physical ergonomics, cognitive ergonomics, and organizational ergonomics) and employee performance
with p<0.05. While the multiple linear regression analysis found that the most contributing ergonomics factors was
physical ergonomics that significantly affects job performance in the electronics industry in Malaysia. Conclusion:
Ergonomics factors can be used to promote improved performance and productivity from the employees in the organization such as awareness training and education.
9.Unraveling the Sugar Rush: A Cross-sectional Study of Knowledge, Attitudes, and Practices Related to Sugar- Sweetened Beverages Consumption among Malaysian Young Adults
Siti Nur Athirah Aisyah Abu Bakar ; Asma&rsquo ; Ali ; Abdul Rais Abdul Rahman ; Abbe Maleyki Mhd Jalil ; Noor Salihah Zakaria
Malaysian Journal of Medicine and Health Sciences 2024;20(No.1):152-160
Introduction: The consumption of sugar-sweetened beverages (SSBs) among young adults in Malaysia has witnessed
a notable increase in recent years, giving rise to concerns regarding the potential adverse health effects, including
obesity and diabetes. Despite the urgent need for targeted interventions, there is a dearth of research examining the
knowledge, attitudes, and practices (KAP) related to SSBs among Malaysian young adults. To address this research
gap, the present study aims to assess the level of KAP concerning SSB intake and its associated factors in this specific
population. Methods: A cross-sectional study was conducted involving 408 Malaysian young adults aged between
15 and 29 years. Respondents completed an online questionnaire survey, which encompassed the assessment of
socio-demographic characteristics and KAP regarding SSB consumption. The collected data were analyzed using
IBM’s Statistical Package for the Social Sciences (SPSS) version 22.0. Spearman correlation tests were performed
at a significance level of 0.05. Results: The majority of respondents demonstrated moderate knowledge (60%) and
practices (60%), while exhibiting a high positive attitude (100%) towards reducing SSB consumption. Significant
correlations were observed between knowledge and attitude (p = 0.003, rs = 0.148) and between knowledge and
practice (p = 0.005, rs = 0.138). Moreover, the attitude scores were found to be significantly associated with gender
(χ2
(1, N = 408) = 10.421, p = 0.001) and locality (χ2
(1, N = 408) = 4.106, p = 0.043), while the practice scores
exhibited a significant association with ethnicity (p = 0.006). Conclusion: This study provides valuable insights into
the relationship between KAP related to SSB consumption and socio-demographic factors among Malaysian young
adults. The findings underscore the importance of utilizing these insights to develop strategic interventions that aim
to curtail SSB consumption and promote a healthy lifestyle, ultimately contributing to the reduction of non-communicable diseases. Health authorities are encouraged to capitalize on these findings to design targeted interventions
tailored to the unique needs and circumstances of this population.
10.Population Growth Demand and Challenges of Health Equality Among Immigrants Towards Healthcare Services in Malaysia
Muhammad Qusyairi Fakuruddin ; Nor Aliya Ayub ; Nor Azila Muhd Aris ; Nur Atiqah Mohd Ahwan ; Siti Bazlina Mohd Rawi ; Rosnah Sutan
International Journal of Public Health Research 2024;14(no.1):1853-1857
Introduction:
Malaysia's economic development increases the demand for immigrant workers
to ensure health equality. To achieve Universal Health Coverage, issues related
to immigrants need to be revisited
Methods:
A narrative review was conducted on specific scopes of health access barriers
among immigrants from Scopus, PubMed, Web of Science, and Google Scholar.
Results:
Immigrants face health inequalities due to complex immigration policies, cultural
and social adaptation differences, language barriers, financial constraints, and
low literacy awareness of healthcare systems.
Conclusions
This brief essay highlights challenges for immigrants adhering to Malaysia’s
Health White Paper strategies in meeting Universal Health Coverage. Expanding
these strategies is vital to uphold immigrants’ fundamental rights and ensure
health equality among the minority group of the population.


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