1.Changes in the prevalence of comorbidity of mental and physical disorders in Singapore between 2010 and 2016.
Edimansyah ABDIN ; Siow Ann CHONG ; Janhavi Ajit VAINGANKAR ; Saleha SHAFIE ; Darren SEAH ; Chun Ting CHAN ; Stefan MA ; Lyn JAMES ; Derrick HENG ; Mythily SUBRAMANIAM
Singapore medical journal 2022;63(4):196-202
INTRODUCTION:
Few studies have examined the changes in the prevalence of comorbidity of mental and physical disorders in recent years. The present study sought to examine whether the prevalence of comorbidity of mental and physical disorders in Singapore showed any changes between 2010 and 2016.
METHODS:
We extracted data from two repeated nationally representative cross-sectional surveys conducted among resident adults aged ≥ 18 years in Singapore. Significant changes were tested using pooled multinomial logistic regression analyses.
RESULTS:
The prevalence of comorbid mental and physical disorders increased significantly from 5.8% in 2010 to 6.7% in 2016. Among those with physical disorders, there were significant increases over time in the prevalence of comorbid generalised anxiety disorder (GAD) (0.1% vs. 0.4%) and obsessive-compulsive disorder (OCD) (1.4% vs. 3.9%) in diabetes mellitus, and alcohol dependence in cardiovascular disorders (0.1% vs. 1.3%). Among those with mental disorders, there were significant increases over time in the prevalence of comorbid diabetes mellitus in OCD (4.1% vs. 10.9%), cancer in major depressive disorder (0.4% vs. 2.4%), and cardiovascular disorders in GAD (0.4% vs. 6.7%) and alcohol dependence (0.9% vs. 11.8%). Significant changes in the overall prevalence of comorbid mental and physical disorders were also observed across age group, education and employment status.
CONCLUSION
The prevalence of comorbid mental and physical disorders increased significantly over time. This finding supports the need for more appropriate clinical management with better integration between mental health and general medical care professionals across all aspects of the healthcare system to treat this comorbidity in Singapore.
Adult
;
Alcoholism/epidemiology*
;
Comorbidity
;
Cross-Sectional Studies
;
Depressive Disorder, Major/epidemiology*
;
Humans
;
Mental Disorders/epidemiology*
;
Prevalence
;
Singapore/epidemiology*
2.The moderating effect of employment status on the relationship between lifetime major depressive disorder and positive mental health.
Rajeswari SAMBASIVAM ; Janhavi Ajit VAINGANKAR ; Edimansyah ABDIN ; Fiona DEVI ; Boon Yiang CHUA ; Saleha SHAFIE ; Sherilyn CHANG ; Shazana SHAHWAN ; Siow Ann CHONG ; Mythily SUBRAMANIAM
Annals of the Academy of Medicine, Singapore 2022;51(2):74-86
INTRODUCTION:
This paper aims to examine the (1) level of positive mental health (PMH), (2) identify the socio-demographic correlates of the PMH domains in the general population, and (3) establish if employment status moderates the relationship between major depressive disorder (MDD) and PMH among those with a lifetime prevalence of MDD.
METHODS:
The Singapore Mental Health Study conducted between 2016 and 2018 included Singapore residents aged ≥18 years. The World Health Organization Composite International Diagnostic Interview version 3.0 was utilised to establish lifetime prevalence of MDD. Moderation analysis was conducted using SPSS PROCESS macro (Hayes, 2017) to assess if employment status moderated the relationship between MDD and PMH.
RESULTS:
Significantly lower PMH total and domain scores were reported by respondents (n=2,270) who endorsed lifetime MDD compared to those who did not. Moderation analysis demonstrated that the effect of MDD on PMH total and domain scores varied considerably across employment status. Based on the interaction plots, the effect of MDD on both PMH total and domain scores was minimal among those employed than unemployed.
CONCLUSION
Healthcare professionals should support the employment needs of those who report lifetime MDD to provide care for an individual's mental well-being in a holistic manner. Acquiring or remaining in employment would be a priority depending on the PMH of the individual. Reducing barriers to employment for those with health issues or creating employment opportunities for this group are concerns that need to be addressed at a societal level.
Adolescent
;
Adult
;
Depressive Disorder, Major/epidemiology*
;
Employment
;
Humans
;
Mental Health
;
Prevalence
;
Unemployment
3.Employers' attitudes towards employing people with mental health conditions.
Yunjue ZHANG ; Jue Hua LAU ; Fiona DEVI ; Janhavi Ajit VAINGANKAR ; Shazana SHAHWAN ; Pratika SATGHARE ; Wen Lin TEH ; Roystonn KUMAR ; Chong Min Janrius GOH ; Yogeswary MANIAM ; Swapna VERMA ; Siow Ann CHONG ; Mythily SUBRAMANIAM
Annals of the Academy of Medicine, Singapore 2022;51(9):578-579
4.Accuracy of self-reported height, weight and BMI in a multiethnic Asian population.
Kumarasan ROYSTONN ; Edimansyah ABDIN ; Rajeswari SAMBASIVAM ; Yunjue ZHANG ; Sherilyn CHANG ; Saleha SHAFIE ; Boon Yiang CHUA ; Janhavi Ajit VAINGANKAR ; Siow Ann CHONG ; Mythily SUBRAMANIAM
Annals of the Academy of Medicine, Singapore 2021;50(4):306-314
INTRODUCTION:
The study assessed whether self-reported height, weight and derived body mass index (BMI) can provide an accurate measure of anthropometric data in a multiethnic adult population in Singapore.
METHODS:
Standardised anthropometric measurements were compared against the self-reported values from 5,132 adult residents in a cross-sectional, epidemiological survey. Discrepancies in self-reports from measurements were examined by comparing overall mean differences. Intraclass correlations, Cohen's kappa and Bland-Altman plots with limits of agreement, and sub-analysis by sex and ethnicity were also explored.
RESULTS:
Data were obtained from 5,132 respondents. The mean age of respondents was 43.9 years. Overall, the height was overestimated (0.2cm), while there was an underestimation of weight (0.8kg) and derived BMI (0.4kg/m2). Women had a larger discrepancy in height (0.35cm, 95% confidence interval [CI] 0.22 to 0.49), weight (-0.95kg, 95% CI -1.11 to -0.79) and BMI (-0.49kg/m2, 95% CI -0.57 to -0.41) compared with men. Height reporting bias was highest among Indians (0.28cm, 95% CI 0.12 to 0.44) compared with Chinese and Malays, while weight (-1.32kg, 95% CI -1.53 to -1.11) and derived BMI (-0.57kg/m2, 95% CI -0.67 to -0.47) showed higher degrees of underreporting among Malays compared with Chinese and Indians. Substantially high self-reported versus measured values were obtained for intraclass correlations (0.96-0.99,
CONCLUSION
Self-reported anthropometric estimates can be used, particularly in large epidemiological studies. However, sufficient care is needed when evaluating data from Indians, Malays and women as there is likely an underestimation of obesity prevalence.
5.Impact of unemployment on mental disorders, physical health and quality of life: Findings from the Singapore Mental Health Study.
Mythily SUBRAMANIAM ; Jue Hua LAU ; Edimansyah ABDIN ; Janhavi Ajit VAINGANKAR ; James Junda TAN ; Yunjue ZHANG ; Sherilyn CHANG ; Shazana SHAHWAN ; Saleha SHAFIE ; Rajeswari SAMBASIVAM ; Siow Ann CHONG
Annals of the Academy of Medicine, Singapore 2021;50(5):390-401
INTRODUCTION:
Nutritional psychiatry is an emerging field of study that investigates the role of diet and nutrition in mental health. Studies conducted in the general population have linked depressive symptoms with poor dietary patterns. The aim of this study was to characterise the dietary intake and analyse the dietary pattern using the Dietary Approach to Stop Hypertension (DASH) in a sample of psychiatric patients in a multiethnic Asian nation.
METHODS:
Participants were recruited from an outpatient clinic and an inpatient unit at the Institute of Mental Health in Singapore. Self-reported dietary habits of a sample of psychiatric patients (N=380) were analysed using DASH. To examine the variables associated with DASH scores, a linear regression was conducted with the full sample and sociodemographic variables.
RESULTS:
Persons with depressive disorders had a mean DASH score of 21.3 (±4.2), while persons with psychotic disorders had a mean DASH score of 21.2 (±4.9). Respondents who were older (B=1.94, 95% confidence interval [CI] 0.91-2.96,
CONCLUSION
Dietary patterns of persons with mental disorders were characterised. A host of sociodemographic factors, and not diagnosis of mental disorders, influenced the dietary quality of people with depressive and psychotic disorders. Clinicians treating psychiatric patients need to be aware of the nuanced reasons behind poor dietary choices and provide targeted psychoeducation to specific subgroups within the patient population.
6.Negative affect moderates the link between body image dissatisfaction and disordered eating among psychiatric outpatients in a multi-ethnic Asian setting.
Wen Lin TEH ; Mithila Valli MAHESH ; Edimansyah ABDIN ; Junda TAN ; Restria Fauziana Binte Abdul RAHMAN ; Pratika SATGHARE ; Kang SIM ; Sutapa BASU ; Gomathinayagam KANDASAMI ; Bhanu GUPTA ; Siow Ann CHONG ; Mythily SUBRAMANIAM
Singapore medical journal 2021;62(10):535-541
INTRODUCTION:
Few studies have investigated the factors that affect the relationship between body image dissatisfaction and disordered eating locally. Our study aimed to investigate the moderating effects of depression and anxiety levels on the body dissatisfaction-disordered eating link in Singapore.
METHODS:
A total of 329 participants completed a set of questionnaires that included various scales pertaining to eating behaviours, body image, psychological distress and quality of life.
RESULTS:
Participants were diagnosed with schizophrenia (47.4%), depression (46.8%) and substance use disorders (5.8%). Moderation analyses revealed that depression (F [9, 251] = 18.50, p < 0.001, R
CONCLUSION
Greater effort should be dedicated to the screening of disordered eating behaviours in psychiatric outpatients presenting with greater psychological distress.
7.Validation of the World Health Organization Disability Assessment Schedule 2.0 among older adults in an Asian country.
Mythily SUBRAMANIAM ; Edimansyah ABDIN ; Janhavi A VAINGANKAR ; Vathsala SAGAYADEVAN ; Shazana SHAHWAN ; Louisa PICCO ; Siow Ann CHONG
Singapore medical journal 2020;61(5):246-253
INTRODUCTION:
As populations age globally and the burden of chronic illnesses increases, valid measures of disability are needed for assessment in the older adult population. The aim of the current analysis was to explore the psychometric properties and validity of the 12-item World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) in an epidemiological survey of older adults in Singapore.
METHODS:
The study comprised secondary data analysis of the Well-being of the Singapore Elderly study. Inclusion criteria for the study were Singapore residents (Singapore citizens and permanent residents) aged 60 years and above. The 12-item interviewer-administered version of the WHODAS 2.0 was used to assess disability in the study. Data on cognition, health status and sociodemographic information were collected. Depression was assessed using the Automated Geriatric Examination for Computer Assisted Taxonomy.
RESULTS:
The study found a one-factor model solution for WHODAS 2.0 with a high internal consistency of all items. The internal consistency for the overall scale was 0.92. The WHODAS 2.0 score positively correlated with multimorbidity, perceived overall health status, depression and subsyndromal depression. There was a significant inverse association between the WHODAS 2.0 score and the cognitive status. After adjustment for all sociodemographic variables in the multiple linear regression analysis, these measures remained significantly associated with the WHODAS 2.0 score.
CONCLUSION
WHODAS 2.0 was found to be a valid measure of disability among older adults. However, further research is required to determine its usefulness as a responsive instrument that can detect change following interventions.
8.Authors' reply.
Saleha SHAFIE ; Siau Pheng LEE ; Samantha Bee Cheng ONG ; Peizhi WANG ; Esmond SEOW ; Hui Lin ONG ; Siow Ann CHONG ; Mythily SUBRAMANIAM
Singapore medical journal 2019;60(2):104-104
9.Successful ageing in Singapore: prevalence and correlates from a national survey of older adults.
Mythily SUBRAMANIAM ; Edimansyah ABDIN ; Janhavi A VAINGANKAR ; Rajeswari SAMBASIVAM ; Esmond SEOW ; Louisa PICCO ; Hong Choon CHUA ; Rathi MAHENDRAN ; Li Ling NG ; Siow Ann CHONG
Singapore medical journal 2019;60(1):22-30
INTRODUCTION:
The current study aimed to estimate the overall prevalence and sociodemographic correlates of successful ageing, as defined by Rowe and Kahn, among a national sample of multiethnic adults aged 60 years and older in Singapore.
METHODS:
Data from older adults who participated in the Well-being of the Singapore Elderly study was analysed. Successful ageing was defined with five indicators: no major diseases; no disability; high cognitive functioning; high physical functioning; and active engagement with life.
RESULTS:
The prevalence of successful ageing was 25.4% in this older population. Older adults aged 75-84 years and ≥ 85 years had 0.3 times and 0.1 times the odds of successful ageing, respectively, than those aged 60-74 years. Compared to older adults of Chinese ethnicity, those of Malay (odds ratio [OR] 0.6) and Indian (OR 0.5) ethnicities were less likely to be associated with successful ageing. Older adults with lower education levels, who had no formal education (OR 0.2), some schooling but did not complete primary education (OR 0.4) or only primary education (OR 0.5), had lower odds of ageing successfully than those with tertiary education.
CONCLUSION
Older adults in Singapore tend to have much more active engagement with life as compared to their counterparts from other countries. Further research into this population is needed, both in terms of qualitative research to gain a better understanding of successful ageing from the older adult's perspective, as well as longitudinal studies that explore behavioural determinants of successful ageing.
Activities of Daily Living
;
Aged
;
Aged, 80 and over
;
Aging
;
Cognition
;
Cross-Sectional Studies
;
Disabled Persons
;
Ethnic Groups
;
Female
;
Health Services for the Aged
;
Health Status
;
Humans
;
Independent Living
;
Male
;
Middle Aged
;
Prevalence
;
Singapore
;
Social Class
;
Surveys and Questionnaires
10.Predictors of General Functioning and Correlates of Quality of Life: A Cross-Sectional Study among Psychiatric Outpatients.
Louisa PICCO ; Ying Wen LAU ; Shirlene PANG ; Anitha JEYAGURUNATHAN ; Janhavi A VAINGANKAR ; Edimansyah ABDIN ; Siow Ann CHONG ; Mythily SUBRAMANIAM
Annals of the Academy of Medicine, Singapore 2018;47(1):3-12
INTRODUCTIONFunctioning and quality of life (QOL) are negatively impacted as a result of mental illness. This study aimed to determine the: i) socio-demographic and clinical correlates of functioning and; ii) associations between functioning and QOL in a multiethnic sample of psychiatric outpatients.
MATERIALS AND METHODSThis was a cross-sectional study of outpatients receiving treatment from a tertiary psychiatric hospital. Functioning was assessed using the Global Assessment of Functioning (GAF) scale, while QOL was measured using the World Health Organization Quality of Life-BREF (WHOQOL-BREF) which comprises 4 domains: physical health, psychological health, social relationships and environment.
RESULTSVarious socio-demographic and clinical correlates were associated with functioning including employment and marital status, education and diagnosis. Depression was the only clinical characteristic which negatively correlated with functioning (= 0.035). Amongst the whole sample, multiple linear regressions revealed that functioning was positively associated with all 4 QOL domains (physical health [<0.001], psychological health [<0.001], social relationships [<0.001] and environment [<0.001]). Further analysis of each diagnostic group revealed that functioning was positively associated with all 4 QOL domains in the anxiety, depression and obsessive compulsive disorder subsamples, while in the schizophrenia subsample, functioning was only significantly associated with all environment domain.
CONCLUSIONFunctional impairments were associated with different socio-demographic and clinical characteristics, which should be addressed when planning tailored treatment and interventions. Given that functioning is significantly associated with QOL, it is crucial to regularly assess and monitor them (in addition to symptomatic outcomes and adopting a more holistic and biopsychosocial approach).

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