In Japan, Max von Pettenkofer is highly regarded as a pioneer of modern hygiene. The contribution of Edmund Alexander Parkes, however, is not yet sufficiently appreciated. This paper outlines the life and achievements of E.A. Parkes and discusses his influence in Japan.

Since the first paper by Milham et al. suggested that occupational exposure to an electromagnetic field (EMF) could increase the risk of adult leukemia, many epidemiological studies on this problem have been published. In this report the method of meta−analysis was used to summarize the results from these papers quantitatively. The combined relative risk of all leukemia (RR=1.11), as well as acute lymphocytic leukemia (RR=1.38), acute myeloid leukemia (RR=1.07) and chronic lymphocytic leukemia (RR=1.14) increased but not significantly. So far, it is difficult to make a consistent conclusion about the relationship of the occupational exposure to EMF and adult leukemia. Further carefully designed case−control and cohort studies using the more valid means of exposure assessment are required.
Leukemia ; Adult ; Risk ; Electromagnetic Fields ; Analysis of substances

Investigation was made on the characteristics of farmwork and its effects on the health of people who engage in mixed farming (rice growing and dairy farming), cultivation of lotus roots, tulip growing, highland vegetable growing, rush growing, greenhouse cultivation of lotus, green pepper growing, chrysanthemum growing and vineyard management. Based on our findings, we pointed out several problems associated with rural medicine. As for a way of making workload assessment, we proposed a new method for analyzing postures farmers assume while they are working. We also suggested a modification to the cumulative fatigue symptoms index (CFSI) so as to make it suitable for farmers.

In a series of studies of the workload of lotus growers and their health condition, we checked up on the results of group health screening of lotus growers in comparison with those of other farmers among Tsuchiura agricultural cooperative members in 1992. During that year, we also carried out a time study of lotus cultiration from planting through harvesting. In 1993, we investigated the lifestyle and behavioral pattern of lotus growers. In 1994, an index of cummulative fatigue symptoms was made for lotus growers and loads exerted on their circulatory system were examined.
These studies brought to light hard facts about lotus growing. The farmers have to work in muddy fields laboriously, and for many hours at that, planting in the hottest season and harvesting in the coldest season for many hours. Even when they feel ill, they cannot afford to leave toiling off for their health. We found many signs and symptoms of physical disorder resulting from overwork and peculiar to lotus growing. To improve the working conditions of lotus growing, we recommended the use of the lotus center as a labor saving mode of work so as to facilitate the introduction of power harvesters or the use of greenhouses.
Although there are many socioeconomic issues such as aging of the farming populace, lack of successors and decline in agricultural economy, we will continue to make efforts at health control to protect the health and welfare of farmers by accumulating our knowlege through studies of the state of lotus farming and the health condition of the lotus farmers in other areas as well.

An epidemiological survey on allergic conditions of 58 male (aged 38.6±11.8yrs) and 47 female (aged 42.2 ± 9.6yrs) farmers engaged in growing chrysanthemums.
Among the subjects, 47% of males and 62% of females had complaints of at least one of inquired allergic symptoms associated with the work. The immediate type of allergic reaction on nasal and/ or upper respiratory system raised in the process of sorting flowers in the working room and delayed ype of contact dermatitis in pinching the lateral bud of chrysanthemums or spraying agricultural chemicals in the field were the main complaints of those farmers.
Incidence of positive reaction for patch testing to six kinds of chrysanthemums was 5% for males and 17% for females and that of eight kinds at agricultural chemicals was 34% and 45% for each sex. And relatively high incidence was also observed in those subjects from other immunological tests such as determination of serum immunoglobulin, prick testing and calculation of eosinophil in blood and rhinorrhoea.
There were 39 (67%) males and 36 (77%) females who had at least one of the abnormal finding of those test items above mentioned. However, not the particular kind of Chrysanthemum cultivated in that area was found to be strong causative allergen for the observed allergic conditions.
From these results, it is indicated that relatively high incidence of allergic disorders may be found in the chrysanthemum growers due to inhalation and/or contact of some kinds of allergens introduced from the process of growing to forwarding, such allergen as Chrysanthemum itself, agricultural chemicals and other elements.

In order to observe the actual work types and the work load of female farmers in various kinds of agriculture that have gradually become a large part of agriculture in Japan as a result of changes in the structure of agricultural production, the authors performed a questionnaire and interview with a large number of female farmers (2, 113) and women in non-agricultural households.
Greenhouse farming was the most common work type for female farmers, followed by tobacco cultivation. The jobs conventionally undertaken by men, that have required a large dynamic work load, have been progressively mechanized, while auxiliary work before and after machinary work remain as manual labor by women. Some clear differences in the work type between full-time farming and part-time farming of female farmers were observed. On the other hand, it does not seem to be easy to estimate the work strain due to the work loads as mentioned above.

In the farm household of “vegetable planting by plastic green house”, “mandarin orange”, “rush (igusa)”, “dairy-farming” and “silk worm”, measurement of energy expenditure in agricultural work and analysis of daily working hours were conducted at the busy season of each crops. The results are as follows:
The energy consumption per day are estimated respectively to be 3300 Cal for male and 2900 Cal for female in the household of the “plastic green house”; 3500 and 2500 Cal in the “mandarin orange”, 3800 and 3600 Cal in the “rush”, 3300 and 2700 Cal in the “dairy-farming”, 3400 and 2700 Cal in the “silk worm”.
The agricultural machines and tools are mainly operated by male and so attached muscular works not yet machanized are carried by female. And management of animals or crops specially required prudent care have a tendency to be also carried by female. Then the average relative metabolic rate (RMR) a working day is relatively higher in female than male, except “mandarin orange”.
In the “rush harvesting” and “dairy-farming”, having the most development of the agricultural mechanization it seems obviousely to be rising the labor efficiency, but because of expansion of management scale and decreasing number of employee the reduction of work load for a worker is not necessory obvious.

Mass health survey was conducted to discuss the relationship between obesity and some factors of agricultural managements and living and working conditions among 349 pairs of housewives and their husbands selected from the rural communities in Kumamoto prefecture.
The prevalence rates of obesity (20% over of the Minowa's standard weights) were 13.1% for housewives of farmers, 13.7% for their husbands and 15.6 % for housewives of non-farmers, 9.2% for their husbands. The significant correlationship was found in the degree of obesity by Minowa's standard between housewives and their husbands (r= 0.1566, P<0.05).
Being compared the prevalence of obesity according with the kinds of each household's producting crops, peoples of the household of “shiitake: cortinellus shiitake”, “vegetables by plastic greenhouse”, “tabacco” and “animal husbandary ” were more likely to be obese and, inversely, those of “barley”, “vegetables in upland” and “sericulture” were less, than those of “rice”, “mandarin orange” and “forestry”. In the household of “vegetables by plastic greenhouse”, “rice”, “barley”, “mandarin orange” and “vegetables in upland” husbands were more obese than housewives and, inversely, in the household of “shiitake” and “forestry” housewives were more obese than husbands.
Peoples of fishing households were less likely to be obese than those of the farm households and/or other profession. Among the households of non-farmers it was noteworthy that higher prevalence rates of obesity were found in housewives than husbands, being inverse finding in the farmers case.
The results suggested that the agricultural management and it's labor conditions, as well as the level of agricultural economics, might strongly affect the occurrence of obesity in the Japanese rural community.

One is inclined to imagine that the incidence of respiratory diseases will be negligible among rural people who live and work in fresh and clean air. On the contrary, however, we have reports on the high incidence of chronic obstructive pulmonary diseases and on the existence of a variety of specific respiratory diseases which are incidental to farm work. To clarify this situation, the Japanese Association of Rural Medicine organized a special study group and carried out various studies with grants from the Ministry of Health and Welfare. This is the study group's summary report of the four year research project prepared in conclusion of the project.
The actual state of respiratory diseases among rural people, as investigated by the present study group, can be summarized as follows:
1) In rural districts, in spite of its freedom air-pollution, there exist in high percentages people suffering from respiratory symptoms and patients of obstructive pulmonary diseases. As the important cause of this phenomenon, farm operations, especially thrashing, rice-hulling, compost preparation, scattering of agricultural chemicals can bementioned, which invite the development of symptoms and their aggravation.
2) Pathologically, farmer's pneumoconiosis attributable to farm operation dust was evidenced, crying for the necessity of dust prevention measure during farm operations.
3) In connection with atopic asthma the study group proved the antigenicity of rice-straw, wheat-straw, celiae of tea-sprout, young leaves, and chrysanthemum leaves. There are also anumber of already known antigens. It is necessary to establish measures for its prevention and treatment.
4) In rural districts of Japan, esp. in stock-raising farm houses, there are in comparatively high percentages those who react positive to fungous antigens which are the causes of farmer's lung. However, there have hitherto been reported only two cases, and the study group added one more. In the future, more extensive practice of immunological tests and clinical follow-ups of the positive cases will be necessary.
5) In view of the results reported above, it is considered that there are numerous questions concerning respiratory troubles and diseases in rural districts which are awaiting further study.