1.Research progress on biofilm microecology in chronic suppurative otitis media.
Xin Cheng ZHONG ; Xiao OUYANG ; Yu Bing LIAO ; Ming Zhu TAO ; Jiao PENG ; Zhi Qing LONG ; Xiang Jie GAO ; Ying CAO ; Ming Hua LUO ; Guo Jiang PENG ; Zhi Xiong ZHOU ; Guan Xiong LEI
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2023;58(6):621-625
2.Clinical spectrum of Tuberculosis Otitis Media (TBOM) and management outcomes
Generoso T. Abes ; Franco Louie LB. Abes ; Teresa Luisa G. Cruz ; Erasmo Gonzalo D.V. Llanes
Acta Medica Philippina 2023;57(9):121-132
		                        		
		                        			Objectives:
		                        			To determine the initial clinical diagnoses of patients with tuberculous otitis media (TBOM), to determine the value of PCR test, biopsy, and ancillary diagnostic procedures in detecting middle ear TB infection, and to establish the differences in treatment outcomes.
		                        		
		                        			Methods:
		                        			The clinical records of twenty-eight patients identified with middle ear TB infection by PCR test and biopsy, from January 2010 to December 2016, were reviewed to determine their initial clinical diagnoses. The positivity rates of PCR test and biopsy were compared. The records of 12 patients included in a previous publication were revisited and included in the present study population. The combined cases were classified according to clinical diagnosis to constitute a summary of demographic characteristics, clinical diagnoses, laboratory tests, and treatment outcomes. Results of diagnostic and surgical procedures were reviewed and analyzed. Clinical findings and hearing test results before and after treatment were compared.
		                        		
		                        			Results:
		                        			Of the 28 patients, eight different clinical diagnoses of patients confirmed with middle ear TB were determined. PCR test diagnosed most cases belonging to the early and chronic stages of the disease process. Biopsy diagnosed mostly the chronic cases but failed to diagnose acute cases and late cases with diagnosis of chronic suppurative otitis media with cholesteatoma. By including the twelve cases that were published in 2011, the range of clinical diagnoses was expanded and an outcome of eleven clinical diagnoses confirmed with TB infection was established. Analysis of treatment outcomes showed that the clinical and hearing outcomes were better for patients managed at the early stage of the disease than for those presenting at the late stages of the disease process who underwent more complicated surgical procedures.
		                        		
		                        			Conclusion
		                        			Our study supports the concept of tuberculous otitis media (TBOM) clinical spectrum, implying a paradigm shift in the established thinking that TBOM presents only as a chronic disease. The combined use of PCR and biopsy is a potential diagnostic tool to improve case detection rate, further broaden the scope of the clinical spectrum, and develop better control and preventive strategies for TBOM.
		                        		
		                        		
		                        		
		                        			Otitis Media, Suppurative
		                        			;
		                        		
		                        			 Polymerase Chain Reaction
		                        			
		                        		
		                        	
3.Acute Suppurative Thyroiditis Secondary to Tuberculosis with Superimposed Bacterial Infection: A case report
Siti Sanaa binti Wan Azman ; Masni binti Mohamad
Journal of the ASEAN Federation of Endocrine Societies 2021;36(2):209-212
		                        		
		                        			
		                        			Acute suppurative thyroiditis is a rare and potentially fatal condition. We present a case of an 18-year-old Malay female who presented with one-week history of painful right sided neck swelling, fever and odynophagia. Neck CT confirms ruptured  multiloculated  abscess  with  posterosuperior  extension  into  prevertebral  space.  Pus  and  tissue  cultured  Streptococcus  anginosus  and  Eikenella  corrodens  with  positive  TB  PCR.  She  responded  well  to  ampicillin/sulbactam  and anti-tuberculosis treatment with no evidence of residual collection from ultrasound.
		                        		
		                        		
		                        		
		                        			Thyroiditis, Suppurative
		                        			
		                        		
		                        	
4.Factors Related to Tympanic Membrane Perforation in Children with Acute Suppurative Otitis Media.
Chao-Yun XIE ; Dong CHEN ; Fu-Xiang LIU
Acta Academiae Medicinae Sinicae 2021;43(4):531-535
		                        		
		                        			
		                        			Objective To explore the factors related to tympanic membrane perforation in children with acute suppurative otitis media,and to provide reference for clinical practice. Methods We reviewed the clinical data of 1274 children with acute suppurative otitis media from February 2017 to May 2020,and analyzed the factors related to tympanic membrane perforation. Results Tympanic membrane perforation occurred in 67 out of the 1274 children with acute suppurative otitis media,with the incidence of 5.27%.The univariate analysis showed that 11 factors including the duration of onset(
		                        		
		                        		
		                        		
		                        			Child
		                        			;
		                        		
		                        			Chronic Disease
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Otitis Media, Suppurative/complications*
		                        			;
		                        		
		                        			Procalcitonin
		                        			;
		                        		
		                        			Risk Factors
		                        			;
		                        		
		                        			Tympanic Membrane Perforation/etiology*
		                        			
		                        		
		                        	
5.Citric Acid as an Alternative to Boric Acid in the Treatment of Chronic Suppurative Otitis Media
Basavraj NAGOBA ; Milind DAVANE
Korean Journal of Family Medicine 2019;40(4):278-279
		                        		
		                        			
		                        			No abstract available.
		                        		
		                        		
		                        		
		                        			Citric Acid
		                        			;
		                        		
		                        			Otitis Media, Suppurative
		                        			
		                        		
		                        	
6.Clinical analysis of otogenic Mouret abscess: a case report.
Xin Ping HAO ; Biao CHEN ; Yong Xin LI
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2018;32(6):472-473
		                        		
		                        			
		                        			Mouret abscess is a rare extracranial complication of suppurative otitis media. It is generally believed to be a deep neck abscess caused by inflammation leading to the rupture of the bony tip of the mastoid tip. The location of Mouret abscess is deep. The symptoms are insidious at the onset, but may eventually spread to the surrounding tissue, and even lead to mediastinal abscess, cavernous sinus thrombosis, meningitis, dyspnea and other serious complications. At present, with the popularization of antibiotics, the occurrence rate of Mouret abscess is very low, and only sporadic cases have been reported.In this paper, a case of Mouret abscess caused by cholesteatoma was analyzed to explore Mouret abscess in terms of the route of infection, clinical manifestations, imaging features, diagnosis and treatment.
		                        		
		                        		
		                        		
		                        			Abscess
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			drug therapy
		                        			;
		                        		
		                        			therapy
		                        			;
		                        		
		                        			Cholesteatoma
		                        			;
		                        		
		                        			complications
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Mastoid
		                        			;
		                        		
		                        			pathology
		                        			;
		                        		
		                        			Meningitis
		                        			;
		                        		
		                        			Neck
		                        			;
		                        		
		                        			pathology
		                        			;
		                        		
		                        			Otitis Media
		                        			;
		                        		
		                        			Otitis Media, Suppurative
		                        			;
		                        		
		                        			complications
		                        			
		                        		
		                        	
7.Nonshaved Ear Surgery: Effect of Hair on Surgical Site Infection of the Middle Ear/Mastoid Surgery and Patients' Preference for the Hair Removal
Dong Hee LEE ; Soonil YOO ; Eunhye SHIN ; Yesun CHO
Journal of Audiology & Otology 2018;22(3):160-166
		                        		
		                        			
		                        			BACKGROUND AND OBJECTIVES: This study aimed 1) to compare the rates of surgical site infection (SSI) between two groups with and without preoperative hair shaving, 2) to compare the bacterial colonization just before the skin incision between them, and 3) to evaluate people’s preference for the hair shaving. SUBJECTS AND METHODS: The retrospective study enrolled cases in which middle ear and mastoid surgery was performed with as well as without hair removal. Main measurement outcomes were the SSI rate within 3 months following the surgery, bacterial culture results obtained from the incision area just before the skin incision, and questionnaire to evaluate the preference for hair shaving from patients with chronic suppurative otitis media but without experience with the ear surgery. RESULTS: This study did not show any difference in the rates of SSI and bacterial colonization between two groups with and without preoperative hair shaving. Most patients without experience with the ear surgery chose the nonshaved ear surgery, even though the questionnaire presented a comment as follow; “Your hair will always grow back as the growth speed of about 1.25 cm per month.” CONCLUSIONS: There is no evidence showing that preoperative shaving of the surgical site is helpful for the SSI than no hair removal. Nonshaved middle ear and mastoid surgery via postauricular approach appears to be preferable. Contrary to doctors’ popular belief, the hair shaving can cause psychological discomfort, especially for women. Now is the time to keep the balance between the professional’s perspective and the patients’ preferences.
		                        		
		                        		
		                        		
		                        			Colon
		                        			;
		                        		
		                        			Ear
		                        			;
		                        		
		                        			Ear, Middle
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Hair Removal
		                        			;
		                        		
		                        			Hair
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Mastoid
		                        			;
		                        		
		                        			Otitis Media, Suppurative
		                        			;
		                        		
		                        			Otologic Surgical Procedures
		                        			;
		                        		
		                        			Preoperative Care
		                        			;
		                        		
		                        			Retrospective Studies
		                        			;
		                        		
		                        			Skin
		                        			;
		                        		
		                        			Surgical Wound Infection
		                        			
		                        		
		                        	
8.Capillary Hemangioma of the temporal bone.
Jose Z FERNANDO ; Rosario R RICALDE
Philippine Journal of Otolaryngology Head and Neck Surgery 2017;32(1):37-40
OBJECTIVES: To discuss a rare case of temporal bone capillary hemangioma and its diagnosis and management.
METHODS:
Design: Case Report
Setting: Tertiary Government Hospital
Patient: One
RESULTS: A 44-year-old woman with a history of on-and-off right ear discharge, tinnitus and decreased hearing, and a pinkish, smooth-surfaced, non-friable, non-pulsating mass occluding the right external auditory canal, was initially treated for chronic suppurative otitis media with aural polyp. A punch biopsy due to persistence of disease despite medical treatment revealed capillary hemangioma. She underwent canal wall down mastoidectomy with obliteration to completely resect the tumor.
CONCLUSION: Capillary hemangiomas of the temporal bone are benign lesions that may lead to complications such as bone erosion, hearing loss, recurrent infection and bleeding if left untreated. Surgery remains the ideal treatment and recurrence is rare and the prognosis is good if resection is complete.
Human ; Female ; Middle Aged ; Ear Canal ; Otitis Media, Suppurative ; Tinnitus ; Hearing Loss ; Temporal Bone ; Deafness ; Mastoid ; Hemangioma, Capillary ; Prognosis ; Biopsy ; Polyps
9.A Case of Piriform Sinus Fistula Complicated with Suppurative Thyroiditis Treated with Chemocauterization Using Trichloroacetic Acid.
Kyung Lae SON ; So Young SHIN ; Ye Jee SHIM ; Heung Sik KIM ; Hee Jung LEE ; Chang Ki YEO
Keimyung Medical Journal 2015;34(1):59-63
		                        		
		                        			
		                        			A 23 months-old girl visited the hospital because of fever and left neck mass. She was diagnosed as acute suppurative thyroiditis with piriform sinus fistula. Thyroid sonography showed perithyroidal abscess formation and thyroid scan showed decreased uptake of Tc-99m pertechnate of both thyroid glands. Magnetic resonance imaging of neck showed abscess cavity extending to the swollen left thyroid gland. And there was tiny fistula between thyroid and piriform sinus in the barium esophagogram. Streptococcus gordonii was isolated on needle aspiration culture. We report a case of piriform sinus fistula of the neck complicated with suppurative thyroiditis. The fistula was treated with chemocauterization using trichloroacetic acid.
		                        		
		                        		
		                        		
		                        			Abscess
		                        			;
		                        		
		                        			Barium
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Fever
		                        			;
		                        		
		                        			Fistula*
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Magnetic Resonance Imaging
		                        			;
		                        		
		                        			Neck
		                        			;
		                        		
		                        			Needles
		                        			;
		                        		
		                        			Pyriform Sinus*
		                        			;
		                        		
		                        			Streptococcus gordonii
		                        			;
		                        		
		                        			Thyroid Gland
		                        			;
		                        		
		                        			Thyroiditis, Suppurative*
		                        			;
		                        		
		                        			Trichloroacetic Acid*
		                        			
		                        		
		                        	
10.Comparison of Arbekacin and Vancomycin in Treatment of Chronic Suppurative Otitis Media by Methicillin Resistant Staphylococcus aureus.
Ji Hee HWANG ; Ju Hyung LEE ; Jeong Hwan HWANG ; Kyung Min CHUNG ; Eun Jung LEE ; Yong Joo YOON ; Mi Kyoung MOON ; Ju Sin KIM ; Kyoung Suk WON ; Chang Seop LEE
Journal of Korean Medical Science 2015;30(6):688-693
		                        		
		                        			
		                        			Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of ear infections. We attempted to evaluate the clinical usefulness of arbekacin in treating chronic suppurative otitis media (CSOM) by comparing its clinical efficacy and toxicity with those of vancomycin. Efficacy was classified according to bacterial elimination or bacteriologic failure and improved or failed clinical efficacy response. Ninety-five subjects were diagnosed with CSOM caused by MRSA. Twenty of these subjects were treated with arbekacin, and 36 with vancomycin. The bacteriological efficacy (bacterial elimination, arbekacin vs. vancomycin: 85.0% vs. 97.2%) and improved clinical efficacy (arbekacin vs. vancomycin; 90.0% vs. 97.2%) were not different between the two groups. However, the rate of complications was higher in the vancomycin group (33.3%) than in the arbekacin group (5.0%) (P=0.020). In addition, a total of 12 adverse reactions were observed in the vancomycin group; two for hepatotoxicity, one for nephrotoxicity, eight for leukopenia, two for skin rash, and one for drug fever. It is suggested that arbekacin be a good alternative drug to vancomycin in treatment of CSOM caused by MRSA.
		                        		
		                        		
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Aged
		                        			;
		                        		
		                        			Anti-Bacterial Agents/administration & dosage
		                        			;
		                        		
		                        			Chronic Disease
		                        			;
		                        		
		                        			Dibekacin/administration & dosage/*analogs & derivatives
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Methicillin-Resistant Staphylococcus aureus/*drug effects
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Otitis Media, Suppurative/diagnosis/*drug therapy/microbiology
		                        			;
		                        		
		                        			Staphylococcal Infections/diagnosis/*drug therapy/microbiology
		                        			;
		                        		
		                        			Treatment Outcome
		                        			;
		                        		
		                        			Vancomycin/*administration & dosage
		                        			;
		                        		
		                        			Young Adult
		                        			
		                        		
		                        	
            

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