1.Short-Term Risk Factors for Distal Junctional Kyphosis after Spinal Reconstruction Surgery in Patients with Osteoporotic Vertebrae
Yuta SAWADA ; Shinji TAKAHASHI ; Hidetomi TERAI ; Minori KATO ; Hiromitsu TOYODA ; Akinobu SUZUKI ; Koji TAMAI ; Akito YABU ; Masayoshi IWAMAE ; Hiroaki NAKAMURA
Asian Spine Journal 2024;18(1):101-109
Methods:
This study included 46 patients who underwent spinal reconstruction surgery for thoracolumbar osteoporotic vertebral fractures and kyphosis and were followed up for 1 year postoperatively. DJK was defined as an advanced kyphosis angle >10° between the LIV and one lower vertebra. The patients were divided into groups with and without DJK. The risk factors of the two groups, such as patient background, surgery-related factors, radiographic parameters, and clinical outcomes, were analyzed.
Results:
The DJK and non-DJK groups included 14 and 32 patients, respectively, without significant differences in patient background. Those with instability in the distal adjacent LIV disc had a significantly higher risk of DJK occurrence (28.6% vs. 3.2%, p=0.027). DJK occurrence significantly increased in those with the sagittal stable vertebra not included in the fixation range (57.1% vs. 18.8%, p=0.020). Other preoperative radiographic parameters were not significantly different. Instability in the distal adjacent LIV disc (adjusted odds ratio, 14.50; p=0.029) and the exclusion of the sagittal stable vertebra from the fixation range (adjusted odds ratio, 5.29; p=0.020) were significant risk factors for DJK occurrence.
Conclusions
Regarding spinal reconstruction surgery in patients with osteoporotic vertebral fractures, instability in the distal adjacent LIV disc and the exclusion of the sagittal stable vertebra from the fixation range were risk factors for DJK occurrence in the short term.
2.An Infant With a Low-grade Brain Tumor Presenting With Atypical Epileptic Seizures
Naoyuki KUROIWA ; Koji TAKAHASHI ; Kentarou SHIRAI ; Shota TAKAHASHI ; Shin HIROTA ; Shinji YAMAMOTO ; Akimitsu WATANABE
Journal of the Japanese Association of Rural Medicine 2023;72(4):325-331
Low-grade epilepsy-associated tumors (LEAT) are brain tumors that should be differentiated as a cause of symptomatic epilepsy in children. The most common initial symptom is epileptic seizure, particularly focal seizures. We present a case of LEAT in which an infant presented to our department with convulsive-like seizures that were observed from approximately 3 months of age. At the first visit, growth and development, including head circumference, were appropriate for age. The seizures were atypical, but ictal video electroencephalography showed abnormal waves indicative of left hemispheric epilepsy. The patient subsequently presented with somnolence and poor feeding, and a sudden increase in head circumference and hydrocephalus were observed. Thus, the patient was urgently admitted to the neurosurgery department of our hospital. Brain MRI showed a suspected brain tumor and elective craniotomy was performed. No epileptic seizures were observed postoperatively. When focal epileptic seizures are observed in infancy, a brain tumor should also be considered as a differential diagnosis, and further examination may be warranted.
3.Potential Applicability of Local Resection With Prophylactic Left Gastric Artery Basin Dissection for Early-Stage Gastric Cancer in the Upper Third of the Stomach
Yoshimasa AKASHI ; Koichi OGAWA ; Katsuji HISAKURA ; Tsuyoshi ENOMOTO ; Yusuke OHARA ; Yohei OWADA ; Shinji HASHIMOTO ; Kazuhiro TAKAHASHI ; Osamu SHIMOMURA ; Manami DOI ; Yoshihiro MIYAZAKI ; Kinji FURUYA ; Shoko MOUE ; Tatsuya ODA
Journal of Gastric Cancer 2022;22(3):184-196
Purpose:
Total or proximal gastrectomy of the upper-third early gastric cancer (u-EGC) often causes severe post-gastrectomy syndrome, suggesting that these procedures are extremely invasive for patients without pathologically positive lymph node (LN) metastasis. This study aimed to evaluate the clinical applicability of a stomach function-preserving surgery, local resection (LR), with prophylactic left gastric artery (LGA)-basin dissection (LGA-BD).
Materials and Methods:
The data of patients with u-EGC (pathologically diagnosed as T1) were retrospectively analyzed. Total gastrectomy was performed in 30 patients, proximal gastrectomy in 45, and subtotal gastrectomy in 6; the LN status was evaluated assuming that the patients had already underwent LR + LGA-BD. This procedure was considered feasible in patients without LN metastases or in patients with cancer in the LGA basin. The reproducibility of the results was also evaluated using an external validation dataset.
Results:
Of the 82 eligible patients, 79 (96.3%) were cured after undergoing LR + LGA-BD, 74 (90.2%) were pathologically negative for LN metastases, and 5 (6.1%) had LN metastases, but these findings were only observed in the LGA basin. Similarly, of the 406 eligible tumors in the validation dataset, 396 (97.5%) were potentially curative. Tumors in the lesser curvature, post-endoscopic resection status, and small tumors (<20 mm) were considered to be stronger indicators of LR + LGA-BD as all subpopulation cases met our feasibility criteria.
Conclusions
More than 95% of the patients with u-EGC might be eligible for LR + LGA-BD.This function-preserving procedure may contribute to the development of u-EGC without pathological LN metastases, especially for tumors located at the lesser curvature.
4.Hochuekkito Prescribed for Qi Deficiency Effectively Shortened the Sleep time of a Woman with Hypersomnia: A Case Report
Journal of the Japanese Association of Rural Medicine 2022;71(1):69-72
The patient was a 36 year-old woman with cold sensitivity who had repeated episodes of herpes labialis. Her average sleep time was 13 h, and she experienced problems in her daily life when she could not get enough sleep, so she was diagnosed as having hypersomnia. She gave birth to her first child at the age of 35 years. She had herpes labialis at 1 month after birth, and lochia continued for 3 months. She also experienced repeated episodes of herpes labialis and continuation of lochia after giving birth to her second child at the age of 36 years. In the examination, abdominal tension was low, and because she reported frequent fatigue and infections, she was diagnosed as having Qi deficiency. Hochuekkito was started internally, and after 2 weeks, she had less lochia and the herpes labialis disappeared. In addition, as her symptoms of hypersomnia improved, she became able to maintain her physical strength without excessive daytime sleepiness even after sleeping for only 5 h. Hochuekkito, which is often used to treat Qi deficiency, may improve Qi deficiency-related symptoms and contribute to improving daily life by shortening the sleep time of people with hypersomnia.
5.Can Conventional Magnetic Resonance Imaging Substitute Three-Dimensional Magnetic Resonance Imaging in the Diagnosis of Lumbar Foraminal Stenosis?
Maruf Mohammad HASIB ; Kentaro YAMADA ; Masatoshi HOSHINO ; Eiji YAMADA ; Koji TAMAI ; Shinji TAKAHASHI ; Akinobu SUZUKI ; Hiromitsu TOYODA ; Hidetomi TERAI ; Hiroaki NAKAMURA
Asian Spine Journal 2021;15(4):472-480
Methods:
We investigated 154 foramina at L5–S1 in 77 patients. All the patients had degenerative lumbar disorders and had undergone both conventional MRI and 3D-MRI during the same visit. Differences between the FSRs calculated from conventional and 3D-MRI reconstructions and any correlations with the plain radiography findings were assessed.
Results:
In foramina that had a FSR of <50% on conventional MRI, the difference between the FSR obtained using conventional MRI and 3D-MRI was 5.1%, with a correlation coefficient of 0.777. For foramina with a FSR ≥50% on conventional MRI, the difference was 20.2%, with a correlation coefficient of 0.54. FSR obtained using 3D-MRI was significantly greater in patients who required surgery than in those who were successfully treated with conservative methods (88% and 42%, respectively). Segments with spondylolisthesis or lateral wedging showed higher FSRs than those without these conditions on both types of MRI.
Conclusions
FSRs <50% obtained using conventional MRI were sufficiently reliable; however, the results were inaccurate for FSRs ≥50%. Patients with high FSRs on 3D-MRI were more likely to require surgical treatment. Therefore, 3D-MRI is recommended in patients with suspected stenosis detected using conventional MRI or plain radiographs.
6.Can Conventional Magnetic Resonance Imaging Substitute Three-Dimensional Magnetic Resonance Imaging in the Diagnosis of Lumbar Foraminal Stenosis?
Maruf Mohammad HASIB ; Kentaro YAMADA ; Masatoshi HOSHINO ; Eiji YAMADA ; Koji TAMAI ; Shinji TAKAHASHI ; Akinobu SUZUKI ; Hiromitsu TOYODA ; Hidetomi TERAI ; Hiroaki NAKAMURA
Asian Spine Journal 2021;15(4):472-480
Methods:
We investigated 154 foramina at L5–S1 in 77 patients. All the patients had degenerative lumbar disorders and had undergone both conventional MRI and 3D-MRI during the same visit. Differences between the FSRs calculated from conventional and 3D-MRI reconstructions and any correlations with the plain radiography findings were assessed.
Results:
In foramina that had a FSR of <50% on conventional MRI, the difference between the FSR obtained using conventional MRI and 3D-MRI was 5.1%, with a correlation coefficient of 0.777. For foramina with a FSR ≥50% on conventional MRI, the difference was 20.2%, with a correlation coefficient of 0.54. FSR obtained using 3D-MRI was significantly greater in patients who required surgery than in those who were successfully treated with conservative methods (88% and 42%, respectively). Segments with spondylolisthesis or lateral wedging showed higher FSRs than those without these conditions on both types of MRI.
Conclusions
FSRs <50% obtained using conventional MRI were sufficiently reliable; however, the results were inaccurate for FSRs ≥50%. Patients with high FSRs on 3D-MRI were more likely to require surgical treatment. Therefore, 3D-MRI is recommended in patients with suspected stenosis detected using conventional MRI or plain radiographs.
7.Delayed surgical site infection after posterior cervical instrumented surgery in a patient with atopic dermatitis: a case report
Hiroshi TAKAHASHI ; Yasuchika AOKI ; Shinji TANIGUCHI ; Arata NAKAJIMA ; Masato SONOBE ; Yorikazu AKATSU ; Junya SAITO ; Manabu YAMADA ; Yasuhiro SHIGA ; Kazuhide INAGE ; Sumihisa ORITA ; Yawara EGUCHI ; Satoshi MAKI ; Takeo FURUYA ; Tsutomu AKAZAWA ; Masao KODA ; Masashi YAMAZAKI ; Seiji OHTORI ; Koichi NAKAGAWA
Journal of Rural Medicine 2020;15(3):124-129
Objective: Atopic dermatitis (AD) is one of the known risk factors for Staphylococcus aureus infection. The authors report the case of a patient with cervical spondylosis and AD who developed delayed surgical site infection after posterior cervical instrumented surgery.Patient: A 39-year-old male presented to our hospital with paralysis of the left upper extremity without any cause or prior injury. He had a history of severe AD. We performed C3–C7 posterior decompression and instrumented fusion based on the diagnosis of cervical spondylotic amyotrophy. One year after surgery, his deltoid and bicep muscle strength were fully recovered. Nevertheless, his neck pain worsened 2 years after surgery following worsening of AD. One month after that, he developed severe myelopathy and was admitted to our hospital. Radiographic findings showed that all the screws had loosened and the retropharyngeal space had expanded. Magnetic resonance imaging and computed tomography showed severe abscess formation and destruction of the C7/T1 vertebrae.Result: We diagnosed him with delayed surgical site infection. Methicillin-resistant Staphylococcus aureus was identified on abscess culture. The patient responded adequately to treatment with antibiotic therapy and two debridements and the infection subsided.Conclusion: We should consider the possibility of delayed surgical site infection when conducting instrumented spinal surgery in patients with severe AD.
9.Predictor of Activities of Daily Living (ADL) Disability in Patients Undergoing Cardiovascular Surgery
Shinji MIZUTA ; Shinya TAKAHASHI ; Mayo OSHITA ; Miwa ARAKAWA ; Akira KATAYAMA
Japanese Journal of Cardiovascular Surgery 2019;48(5):299-304
Objectives: The aim of this study was to investigate the relationship between preoperative 10m gait speed and ADL disability in patients undergoing cardiovascular surgery. Methods: There were 131 patients who underwent scheduled cardiovascular surgery and pre and postoperative ADL evaluation from June 2014 to December 2017 in our hospital. A total of 19 patients, including 13 whose Barthel Index (BI) was lower than before surgery at discharge and 6 who had a long-term hospital stay of 6 weeks or more after surgery, was defined as the ADL disability group. The other 119 patients were defined as the control group. We retrospectively compared the two groups and searched for predictors of postoperative ADL disability. Results and Conclusions: An independent predictor of postoperative ADL disability was identified: more than 7.04seconds for walking 10m.
10.Influence of Diabetes Mellitus on Surgical Outcomes in Patients with Cervical Myelopathy: A Prospective, Multicenter Study
Shinji TANISHIMA ; Tokumitsu MIHARA ; Atsushi TANIDA ; Chikako TAKEDA ; Masaaki MURATA ; Toshiaki TAKAHASHI ; Koji YAMANE ; Tsugutake MORISHITA ; Yasuo MORIO ; Hiroyuki ISHII ; Satoru FUKATA ; Yoshiro NANJO ; Yuki HAMAMOTO ; Toshiyuki DOKAI ; Hideki NAGASHIMA
Asian Spine Journal 2019;13(3):468-477
STUDY DESIGN: Multicenter, prospective study. PURPOSE: To investigate the effects of diabetes mellitus (DM) on surgical outcomes in patients with cervical myelopathy. OVERVIEW OF LITERATURE: To date, few studies have investigated the influence of postoperative blood glucose or glycated hemoglobin (HbA1c) levels on surgical outcomes. METHODS: The participants were patients who underwent surgery for the treatment of cervical spondylotic myelopathy and ossification of the posterior longitudinal ligament. The 61 cases were evaluated preoperatively and 1 year postoperatively using the Japanese Orthopaedic Association (JOA) scores and the JOA Cervical Myelopathy Evaluation Questionnaire (JOACMEQ). The study variables included fasting blood glucose and HbA1c levels measured preoperatively and at 1 week, 4 weeks, and 1 year postoperatively; the F-wave conduction velocity, latency, rate of occurrence, and M-wave latency in the ulnar and tibial nerves were measured preoperatively and at 1 year postoperatively. The patients were divided into a group without diabetes (N group, 42 patients) and a group with diabetes (DM group, 19 patients). We then assessed the associations between the surgical outcomes and each of the study variables. RESULTS: JOA scores significantly improved in both groups; however, no significant between-group differences were found. There was no significant improvement in the JOACMEQ scores, which assessed cervical function, upper and lower limb function, and bladder function in both groups. We then subdivided the DM group into those with a good control of HbA1c after 1 year (DMG group, 12 patients) and those with HbA1c deterioration after 1 year (DMB group, seven patients), prior to comparing the surgical outcomes. The JOACMEQ scores for upper and lower limb function significantly improved in the DMG group (p<0.01). Compared with the DMB group, there were no significant increases in upper or lower limb function scores in the DMG group. CONCLUSIONS: Poor glycemic control might prevent postoperative functional recovery of the spinal cord.
Asian Continental Ancestry Group
;
Blood Glucose
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Diabetes Mellitus
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Electromyography
;
Fasting
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Hemoglobin A, Glycosylated
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Humans
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Longitudinal Ligaments
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Lower Extremity
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Neck
;
Prospective Studies
;
Spinal Cord
;
Spinal Cord Compression
;
Spinal Cord Diseases
;
Tibial Nerve
;
Treatment Outcome
;
Urinary Bladder


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