1.The role of percutaneous neurolysis in lumbar disc herniation: systematic review and meta-analysis
Laxmaiah MANCHIKANTI ; Emilija KNEZEVIC ; Nebojsa Nick KNEZEVIC ; Mahendra R. SANAPATI ; Alan D. KAYE ; Srinivasa THOTA ; Joshua A. HIRSCH
The Korean Journal of Pain 2021;34(3):346-368
		                        		
		                        			Background:
		                        			Recalcitrant disc herniation may result in chronic lumbar radiculopathy or sciatica. Fluoroscopically directed epidural injections and other conservative modalities may provide inadequate improvement in some patients. In these cases, percutaneous neurolysis with targeted delivery of medications is often the next step in pain management. 
		                        		
		                        			Methods:
		                        			An evidence-based system of methodologic assessment, namely, the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) was used. Multiple databases were searched from 1966 to January 2021. Principles of the best evidence synthesis were incorporated into qualitative evidence synthesis.The primary outcome measure was the proportion of patients with significant painrelief and functional improvement (≥ 50%). Duration of relief was categorized as short-term (< 6 months) and long-term (≥ 6 months). 
		                        		
		                        			Results:
		                        			This assessment identified one high-quality randomized controlled trial (RCT) and 5 moderate-quality non-randomized studies with an application of percutaneous neurolysis in disc herniation. Overall, the results were positive, with level II evidence. 
		                        		
		                        			Conclusions
		                        			Based on the present systematic review, with one RCT and 5 nonrandomized studies, the evidence level is II for percutaneous neurolysis in managing lumbar disc herniation.
		                        		
		                        		
		                        		
		                        	
2.The role of percutaneous neurolysis in lumbar disc herniation: systematic review and meta-analysis
Laxmaiah MANCHIKANTI ; Emilija KNEZEVIC ; Nebojsa Nick KNEZEVIC ; Mahendra R. SANAPATI ; Alan D. KAYE ; Srinivasa THOTA ; Joshua A. HIRSCH
The Korean Journal of Pain 2021;34(3):346-368
		                        		
		                        			Background:
		                        			Recalcitrant disc herniation may result in chronic lumbar radiculopathy or sciatica. Fluoroscopically directed epidural injections and other conservative modalities may provide inadequate improvement in some patients. In these cases, percutaneous neurolysis with targeted delivery of medications is often the next step in pain management. 
		                        		
		                        			Methods:
		                        			An evidence-based system of methodologic assessment, namely, the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) was used. Multiple databases were searched from 1966 to January 2021. Principles of the best evidence synthesis were incorporated into qualitative evidence synthesis.The primary outcome measure was the proportion of patients with significant painrelief and functional improvement (≥ 50%). Duration of relief was categorized as short-term (< 6 months) and long-term (≥ 6 months). 
		                        		
		                        			Results:
		                        			This assessment identified one high-quality randomized controlled trial (RCT) and 5 moderate-quality non-randomized studies with an application of percutaneous neurolysis in disc herniation. Overall, the results were positive, with level II evidence. 
		                        		
		                        			Conclusions
		                        			Based on the present systematic review, with one RCT and 5 nonrandomized studies, the evidence level is II for percutaneous neurolysis in managing lumbar disc herniation.
		                        		
		                        		
		                        		
		                        	
3.Extraparenchymal (Racemose) Neurocysticercosis and Its Multitude Manifestations: A Comprehensive Review.
Rohan R MAHALE ; Anish MEHTA ; Srinivasa RANGASETTY
Journal of Clinical Neurology 2015;11(3):203-211
		                        		
		                        			
		                        			Neurocysticercosis is an infection of the central nervous system caused by the larval form of the pork tapeworm Taenia solium. In the brain it occurs in two forms: parenchymal and extraparenchymal or racemose cysts. The clinical presentation of racemose cysts is pleomorphic, and is quite different from parenchymal cysticercosis. The clinical diagnosis of racemose cysts is quite challenging, with neuroimaging being the mainstay. However, the advent of newer brain imaging modalities has made a more accurate diagnosis possible. The primary focus of this article is racemose neurocysticercosis and its multitude manifestations, and includes a discussion of the newer diagnostic modalities and treatment options.
		                        		
		                        		
		                        		
		                        			Brain
		                        			;
		                        		
		                        			Central Nervous System
		                        			;
		                        		
		                        			Cysticercosis
		                        			;
		                        		
		                        			Diagnosis
		                        			;
		                        		
		                        			Neurocysticercosis*
		                        			;
		                        		
		                        			Neuroimaging
		                        			;
		                        		
		                        			Taenia solium
		                        			
		                        		
		                        	
4.Short Axillary Vein and an Axillary Venous Ladder Formed by Basilic and Brachial Veins – An Anatomical and Clinical Perspective
Satheesha Nayak B ; Srinivasa RS ; Ashwini AP ; Naveen K ; Swamy RS ; Deepthinath R ; Surekha DS ; Prakashchandra S
Journal of Surgical Academia 2015;5(2):29-32
		                        		
		                        			
		                        			Knowledge of anatomic variants of veins in the arm and axilla play a key role in planning of successful venous
access. Possible anatomic variants of axillary vein, brachial vein and basilic vein and their clinical implications have
been well described in the literature. We report a rare case of formation of a short axillary vein associated with
complex venous communications between the basilic and brachial veins forming a venous ladder in the axilla, in
formalin embalmed male cadaver. Axillary vein was formed in the upper part of the axilla by the fusion of basilic
vein and unpaired brachial vein, and it was about 3cm in length. The higher-up confluence of basilic and brachial
veins was also associated with presence of three communicating veins between the basilic and brachial veins in the
axilla. Knowledge of reported venous variations is very useful during preoperative venous mapping and also for
planning and execution of various surgical invasive procedures involving these veins.
		                        		
		                        		
		                        		
		                        			Axillary Vein
		                        			
		                        		
		                        	
5.A Case of Bilateral Occipital Lobe Infarcts Following Indian Tree Viper Bite.
Rohan MAHALE ; Anish MEHTA ; Mahendra JAVALI ; R SRINIVASA
Journal of Stroke 2014;16(3):205-207
		                        		
		                        			
		                        			No abstract available.
		                        		
		                        		
		                        		
		                        			Occipital Lobe*
		                        			
		                        		
		                        	
6.A Case of Bilateral Occipital Lobe Infarcts Following Indian Tree Viper Bite.
Rohan MAHALE ; Anish MEHTA ; Mahendra JAVALI ; R SRINIVASA
Journal of Stroke 2014;16(3):205-207
		                        		
		                        			
		                        			No abstract available.
		                        		
		                        		
		                        		
		                        			Occipital Lobe*
		                        			
		                        		
		                        	
7.A Rare Unilateral Variation in the Course of External and Internal Carotid Arteries
Satheesha BN, Srinivasa RS, Swamy RS ; Deepthinath R ; Sudarshan S ; Naveen K
Journal of Surgical Academia 2014;4(2):35-37
		                        		
		                        			
		                        			Vascular variations in the neck region are not uncommon. Knowledge of incidence of morphological variations in
the course and branching of the carotid arteries is important for radiological interpretation and surgical correction
when they are symptomatic. Internal carotid artery (ICA) is known to show elongation in its extra cranial course.
Previous studies have demonstrated the incidence and clinical symptoms of this morphological entity. However, the
occurrence of elongation and looping of the external carotid artery (ECA) is seldom reported in the literature. During
regular dissections, we came across a rare case of unilateral morphological variation of both ECA and ICA, in a male
cadaver aged about 55 years. ICA presented a curved course with convexity directed posteriorly, at the level of the
C2-C3 vertebrae. ECA presented a pronounced kinking or coiling, one inch below the level of the angle of the
mandible. In addition, a linguo-facial trunk arising from the ECA also presented a pronounced kinking throughout its
entire length.
		                        		
		                        		
		                        		
		                        	
8.Unusual Path of Branches of Ilioinguinal Nerve: A Clinically Important Anatomic Variant
Satheesha BN ; Srinivasa RS ; Prakashchandra S ; Surekha DS ; Deepthinath R ; Raghu J ; Abhinitha P ; Jyothsna P
Journal of Surgical Academia 2014;4(2):59-61
		                        		
		                        			
		                        			Ilioinguinal nerve is a collateral branch of lumbar plexus. Its anatomical variations in relation to adjacent
musculoaponeurotic structures play a crucial role in the development of neuropathies associated with lower
abdominal surgeries. In this report, we present a rare case of unusual course and branches of the ilioinguinal nerve, in
a 55-year-old male cadaver. In the lateral part of inguinal canal ilioinguinal nerve gave three branches. Two of its
branches pierced the external oblique aponeurosis, about 6 cm above the pubic symphysis, to supply the skin of the
lower part of the anterior abdominal wall. Another branch pierced the conjoint tendon, in the medial part of the
inguinal canal about 2 cm above the superficial inguinal ring. Knowledge of unusual path of these branches may be
important to avoid injuries during the surgical repair of groin hernias. Further care should be taken while dealing
with the conjoint tendon in the Bassini procedure.
		                        		
		                        		
		                        		
		                        	
9.Unilateral duplication of vas deferens: a cadaveric case report.
Srinivasa Rao SIRASANAGANDLA ; Satheesha B NAYAK ; Raghu JETTI ; Kumar M R BHAT
Anatomy & Cell Biology 2013;46(1):79-81
		                        		
		                        			
		                        			Duplication of vas deferens is a rare congenital anomaly. All previously reported cases of this rare anomaly were identified during procedures such as orchiepexy, inguinal hernia repair, vasectomy, varicocoelectomy, and radical prostatectomy. Here, we report a case of unilateral duplicated vas deferens noted in an adult cadaver during regular dissection for medical students. The right spermatic cord contained 2 separate and completely developed cord-like structures. Both cords communicated separately with the tail of the epididymis. When traced cranially, both traversed the inguinal canal as content of the spermatic cord and finally fused at the level of the deep inguinal ring. No other variations were found in the testis or epididymis, and no variations were seen in the left spermatic cord. In addition, no associated renal abnormalities were noted.
		                        		
		                        		
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Cadaver
		                        			;
		                        		
		                        			Epididymis
		                        			;
		                        		
		                        			Hernia, Inguinal
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Inguinal Canal
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Prostatectomy
		                        			;
		                        		
		                        			Spermatic Cord
		                        			;
		                        		
		                        			Students, Medical
		                        			;
		                        		
		                        			Testis
		                        			;
		                        		
		                        			Vas Deferens
		                        			;
		                        		
		                        			Vasectomy
		                        			
		                        		
		                        	
10.Analysis of the morphometry and variations in the extensor digitorum brevis muscle: an anatomic guide for muscle flap and tendon transfer surgical dissection.
Srinivasa Rao SIRASANAGANDLA ; Ravindra S SWAMY ; Satheesha B NAYAK ; Nagabhooshana S SOMAYAJI ; Mohandas K G RAO ; Kumar M R BHAT
Anatomy & Cell Biology 2013;46(3):198-202
		                        		
		                        			
		                        			The extensor digitorum brevis muscle (EDB) is a practical option for use as an island flap or free flap when reconstructing soft tissue defects in the ankle as well as in the entire lower limb. It is frequently used to correct crossover toe deformity and other painful toe disorders. We evaluated the morphometry of the EDB in 44 formalin-fixed limbs. Length and width of the muscles were measured. Surface area was calculated as the product of length and width of the muscle. The length of each tendon was also measured from its origin to the point of distal attachment. Presence of any additional tendons was noted. Mean length, width, and surface area of the muscle were 7.39+/-0.71 cm, 4.1+/-0.37 cm, and 30.5+/-4.78 cm2 on the right side and 7.2+/-0.84 cm, 3.9+/-0.37 cm, and 28.4+/-5.35 cm2 on the left side, respectively. Morphometry of the tendons revealed that the tendon of the great toe had the highest mean length (9.5 cm) and the tendon of the fourth toe had the lowest mean length (6.3 cm). Four of the limbs studied (9.09%) had only three tendons. Three of the limbs studied (6.81%) had five tendons, and in one exceptional case (2.27%), six tendons were detected. These observations have significant value and are applicable to plastic and orthopedic surgery.
		                        		
		                        		
		                        		
		                        			Animals
		                        			;
		                        		
		                        			Ankle
		                        			;
		                        		
		                        			Congenital Abnormalities
		                        			;
		                        		
		                        			Extremities
		                        			;
		                        		
		                        			Free Tissue Flaps
		                        			;
		                        		
		                        			Lower Extremity
		                        			;
		                        		
		                        			Muscles
		                        			;
		                        		
		                        			Orthopedics
		                        			;
		                        		
		                        			Plastics
		                        			;
		                        		
		                        			Tendon Transfer
		                        			;
		                        		
		                        			Tendons
		                        			;
		                        		
		                        			Toes
		                        			
		                        		
		                        	
            
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