Aedes mosquito-borne diseases such as dengue, chikungunya and Zika are classified as emerging and re-emerging infectious diseases across the globe. There is no permanent treatment or vaccine developed and the effort is still on-going. Several mitigation methods were introduced to control Aedes mosquitoes and the outbreak of these diseases. However, they had only been temporarily effective due to the lack of practices and participation of all community members who can contribute to the prevention of Aedes mosquito-borne diseases. Awareness on these diseases is still limited while the knowledge, attitude and practice of an individual strongly determines their level of involvement at community level towards prevention. This review highlights an overview of knowledge, attitude and practice studies on Aedes mosquito-borne diseases among different communities in Malaysia, the limitation in the knowledge, attitude and practice studies and the improvement that can be made to the knowledge, attitude and practice approach to encourage a more inclusive community involvement in Malaysia.

Chikungunya is an infection caused by chikungunya virus which at present has spread to new countries and continents. Chikungunya is associated with self-limiting and non-fatal infection in the past. However, in recent times, increased severity of the disease has been reported resulting in health and economic burden. The threat and burden of chikungunya would grow in future in the absence of specific antiviral or vaccine to control or eliminate the infection. This review discusses chikungunya in general including transmission of its etiological agent and clinical manifestations of the disease. Subsequently, management and treatment of chikungunya virus will be reviewed with particular emphasis on natural products or their active compounds with potential anti-chikungunya virus activities.

Objective: To examine the proapoptotic properties of Oroxylum indicum methanol extract on cervical cancer cells. Methods: Methylene blue assay was used to determine the IC