Objective: Studies have reported that animal-assisted therapy (AAT) intervention can improve patient motivation to complete rehabilitation treatment.Methods: AAT was administered four times for a patient whose rehabilitation treatment was hindered by pain and depression following cervical myelopathy surgery. Ward nurses evaluated the patient's behavior and facial expressions before and during each AAT session using our hospital's own Faces Pain Scale. The AAT intervention was timed to coincide with the implementation of training items that were likely to induce pain.Results: The patient, who underwent cervical myelopathy surgery and whose rehabilitation treatment was severely hindered, reported significantly improved treatment motivation after the AAT intervention. A significantly better treatment response was obtained immediately after the AAT intervention. The Faces Pain Scale score was the worst prior to starting AAT (at 5). However, it peaked at 1 and remained there from the initial intervention to the fourth and final intervention. These results suggest immediate and lasting effects of AAT.Conclusion: Significant changes were observed after the initial AAT intervention, suggesting that its effect was more significant for the awareness of pain and motivation for rehabilitation than for pain relief.

Objective: Studies have reported that animal-assisted therapy (AAT) intervention can improve patient motivation to complete rehabilitation treatment.Methods: AAT was administered four times for a patient whose rehabilitation treatment was hindered by pain and depression following cervical myelopathy surgery. Ward nurses evaluated the patient's behavior and facial expressions before and during each AAT session using our hospital's own Faces Pain Scale. The AAT intervention was timed to coincide with the implementation of training items that were likely to induce pain.Results: The patient, who underwent cervical myelopathy surgery and whose rehabilitation treatment was severely hindered, reported significantly improved treatment motivation after the AAT intervention. A significantly better treatment response was obtained immediately after the AAT intervention. The Faces Pain Scale score was the worst prior to starting AAT (at 5). However, it peaked at 1 and remained there from the initial intervention to the fourth and final intervention. These results suggest immediate and lasting effects of AAT.Conclusion: Significant changes were observed after the initial AAT intervention, suggesting that its effect was more significant for the awareness of pain and motivation for rehabilitation than for pain relief.

Objective：We analyzed whether activities of daily living (ADL) had an additive effect on the discharge destination of hospitalized older patients with internal medicine.Methods：Of the 691 patients hospitalized for medical illness aged 65 years or older who received physical therapy during this study period, 186 patients were included in the analysis. The main outcome was the discharge destination. Participants were categorized in the home discharge group and other institution group. The Barthel Index (BI) was used to assess the ADL at the first physical therapy session. Multivariate logistic regression analysis was used to estimate the influence of the BI on determining the discharge destination. The cut-off point of the BI score was evaluated using a receiver operating characteristic curve.Results：During the follow-up period, 17 participants (9.1%) could not be discharged to their homes. Logistic regression analysis showed that the BI influenced discharge destinations (odds ratio：1.54；95% confidence intervals：1.23-1.89). The cut-off point of the BI score for determining home discharge was 72.5 (sensitivity, 0.80；specificity, 0.94；area under the curve, 0.94；positive predictive value：0.99, negative predictive value：0.32).Conclusions：These findings suggest that the BI is a useful predictor for determining the potential destination of hospitalized older patients following discharge. However, the results of this study have limitations such as a low negative predictive value and a limited number of subjects.

Objective：We analyzed whether activities of daily living (ADL) had an additive effect on the discharge destination of hospitalized older patients with internal medicine.Methods：Of the 691 patients hospitalized for medical illness aged 65 years or older who received physical therapy during this study period, 186 patients were included in the analysis. The main outcome was the discharge destination. Participants were categorized in the home discharge group and other institution group. The Barthel Index (BI) was used to assess the ADL at the first physical therapy session. Multivariate logistic regression analysis was used to estimate the influence of the BI on determining the discharge destination. The cut-off point of the BI score was evaluated using a receiver operating characteristic curve.Results：During the follow-up period, 17 participants (9.1%) could not be discharged to their homes. Logistic regression analysis showed that the BI influenced discharge destinations (odds ratio：1.54；95% confidence intervals：1.23-1.89). The cut-off point of the BI score for determining home discharge was 72.5 (sensitivity, 0.80；specificity, 0.94；area under the curve, 0.94；positive predictive value：0.99, negative predictive value：0.32).Conclusions：These findings suggest that the BI is a useful predictor for determining the potential destination of hospitalized older patients following discharge. However, the results of this study have limitations such as a low negative predictive value and a limited number of subjects.

Objective: In this study, we conducted a questionnaire survey of hospital pharmacists throughout Japan with the aim of identifying the most-requested in-hospital preparations and off-label use drugs, and exploring the possibility of commercializing them.Methods: The Commercialization Study Group of the Japanese Society of Hospital Pharmacists conducted a questionnaire survey on the Japanese Society of Hospital Pharmacists website targeting hospital pharmacists who are members of the Japanese Society of Hospital Pharmacists. The period of the survey was from February 1, 2019 until January 21, 2020. In the questionnaire, the respondents wrote specific product names (generic names), specifications, and dosage forms that they would like to see improved and made commercially available in a free-text format. In addition, respondents chose their reasons for wanting the product to be improved or made commercially available from a list.Results: A total of 1,627 drugs were requested to be made commercially available. After duplicates and insufficient descriptions were excluded, the total was 553. The drugs that were most frequently requested were Levothyroxine suppositories, followed by Mohs’ ointment and Ulinastatin vaginal suppositories.Discussion: This survey identified certain drugs that pharmacists want to be commercialized and the specific reasons why. In-hospital preparations not only benefit patients whose diseases are becoming more complex and difficult to treat with existing prescription drugs, but also enable pharmacists to demonstrate their abilities. We believe that the commercialization of these important in-hospital preparations and off-label drugs will help avoid various risks associated with dispensing them and enhance the pharmacy profession. For this reason, pharmaceutical drug companies should conduct further surveys on the actual use of and literature research on the efficacy and safety of the drugs that were ranked high on the questionnaire and start considering their commercialization.